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  1. Article ; Online: A Novel CT Score Reveals More About Air Trapping in Asthma.

    Svenningsen, Sarah / Kirby, Miranda

    American journal of respiratory and critical care medicine

    2024  

    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202312-2284ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
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  2. Article ; Online: Improving strategic planning for nature: Panacea or pandora's box for the built and natural environment?

    Scott, Alister / Kirby, Matthew

    Ambio

    2024  

    Abstract: This paper assesses how strategic planning for nature can be improved for England's built and natural environment using mainstreaming and landscape-scale concepts. Whilst both concepts feature in academic literature, there has been limited attention on ... ...

    Abstract This paper assesses how strategic planning for nature can be improved for England's built and natural environment using mainstreaming and landscape-scale concepts. Whilst both concepts feature in academic literature, there has been limited attention on their role as catalytic agents for strategic planning. Addressing this gap, evidence is used from two stakeholder workshops involving 62 senior policy experts managing a range of operational and hypothetical strategic spatial planning challenges. The results reveal a significantly weakened strategic planning arena characterised by policy disintegration, short termism and uncertainty. Key findings highlight the fallacy of pursuing strategic planning for nature in isolation from wider policy integration fusing environmental, economic and social components from the outset. Current barriers to progress include institutional inertia, technocratic vocabularies and neoliberalist priorities exacerbated by a weak underlying theory. Conversely opportunities for mainstreaming processes may help knowledge generation and exchange within transdisciplinary partnerships, whilst landscape scale thinking can improve understanding of issues using natures inherent geometry transforming processes and outcomes. The paper recommends the adoption of strategic planning pathways using mainstreaming and landscape-scale approaches working in tandem. Whilst focused on the English context, our findings are transferable to other planning systems in the Global North, especially those championing neoliberal market led policies.
    Language English
    Publishing date 2024-03-15
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 120759-3
    ISSN 1654-7209 ; 0044-7447
    ISSN (online) 1654-7209
    ISSN 0044-7447
    DOI 10.1007/s13280-024-01995-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  3. Article ; Online: Are CT-based exacerbation prediction models ready for use in chronic obstructive pulmonary disease?

    Makimoto, Kalysta / Kirby, Miranda

    The Lancet. Digital health

    2023  Volume 5, Issue 2, Page(s) e54–e55

    MeSH term(s) Humans ; Pulmonary Disease, Chronic Obstructive ; Disease Progression ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2589-7500
    ISSN (online) 2589-7500
    DOI 10.1016/S2589-7500(22)00237-0
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  4. Article ; Online: Quantitative CT Scan Imaging of the Airways for Diagnosis and Management of Lung Disease.

    Kirby, Miranda / Smith, Benjamin M

    Chest

    2023  Volume 164, Issue 5, Page(s) 1150–1158

    Abstract: CT scan imaging provides high-resolution images of the lungs in patients with chronic respiratory diseases. Extensive research over the last several decades has focused on developing novel quantitative CT scan airway measurements that reflect abnormal ... ...

    Abstract CT scan imaging provides high-resolution images of the lungs in patients with chronic respiratory diseases. Extensive research over the last several decades has focused on developing novel quantitative CT scan airway measurements that reflect abnormal airway structure. Despite many observational studies demonstrating that associations between CT scan airway measurements and clinically important outcomes such as morbidity, mortality, and lung function decline, few quantitative CT scan measurements are applied in clinical practice. This article provides an overview of the relevant methodologic considerations for implementing quantitative CT scan airway analyses and provides a review of the scientific literature involving quantitative CT scan airway measurements used in clinical or randomized trials and observational studies of humans. We also discuss emerging evidence for the clinical usefulness of quantitative CT scan imaging of the airways and discuss what is required to bridge the gap between research and clinical application. CT scan airway measurements continue to improve our understanding of disease pathophysiologic features, diagnosis, and outcomes. However, a literature review revealed a need for studies evaluating clinical benefit when quantitative CT scan imaging is applied in the clinical setting. Technical standards for quantitative CT scan imaging of the airways and high-quality evidence of clinical benefit from management guided by quantitative CT scan imaging of the airways are required.
    MeSH term(s) Humans ; Lung Diseases/diagnostic imaging ; Lung ; Tomography, X-Ray Computed/methods ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.02.044
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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.45: Show issues Location:
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  5. Article ; Online: Please Stop Smoking: 10-year Emphysema Progression in the COPDGene Study.

    Parraga, Grace / Kirby, Miranda

    Radiology

    2023  Volume 307, Issue 4, Page(s) e230429

    MeSH term(s) Humans ; Pulmonary Emphysema/diagnostic imaging ; Smoking/adverse effects ; Emphysema ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.230429
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    In stock of ZB MED Cologne/Königswinter

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  6. Article: HIV and HCV Epidemics: Lessons for Lawyers and Policymakers.

    Kirby, Michael

    Journal of law and medicine

    2019  Volume 26, Issue 3, Page(s) 583–594

    Abstract: This article arises from a summary offered by the author to an international conference held at Wilton Park, England, on policy and action necessary to respond effectively to the epidemics caused by the Human Immunodeficiency Virus (HIV) and Hepatitis C ... ...

    Abstract This article arises from a summary offered by the author to an international conference held at Wilton Park, England, on policy and action necessary to respond effectively to the epidemics caused by the Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). The article begins with 10 lessons derived by the author from his involvement with the HIV epidemic since 1989. These lessons compare and contrast the features of the HIV/AIDS epidemic and those of the HCV epidemic. Although there is overlap between the persons exposed to the respective viruses, HCV is different in two important respects. First, unlike HIV, Hepatitis C can be cured with available but usually expensive therapy. No cure or vaccine has yet been developed for HIV. Second, HIV resulted in a major international response stimulated by engagement with people living with that virus. HCV attracts event greater stigma. Because of national and international treaty law and national criminal law, stigma is even greater in the case of HCV. The article identifies 10 lessons to be learned, including the need for reform of national and international drug control law. It concludes with a list of urgent initiatives that are needed globally to combat the growing but treatable HCV epidemic.
    MeSH term(s) England ; Epidemics ; HIV Infections/epidemiology ; Health Policy ; Hepacivirus ; Hepatitis C/epidemiology ; Humans ; Lawyers ; Substance Abuse, Intravenous
    Language English
    Publishing date 2019-04-29
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1236328-5
    ISSN 1320-159X
    ISSN 1320-159X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4288: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: The impact of climate change, population growth and development on sustainable water security in Bangladesh to 2100.

    Kirby, Mac / Mainuddin, Mohammed

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 22344

    Abstract: There are concerns that groundwater use for irrigation and for urban water supply is unsustainable in some parts of Bangladesh, particularly in the agriculturally productive northwest region. We use an integrated population - GDP - food - water model to ... ...

    Abstract There are concerns that groundwater use for irrigation and for urban water supply is unsustainable in some parts of Bangladesh, particularly in the agriculturally productive northwest region. We use an integrated population - GDP - food - water model to examine water demand to 2100 in Bangladesh in development scenarios relevant to food and water security. The results indicate that irrigation water demand is projected to increase in coming decades, but later in the century it may decrease due to increasing crop yields and a falling population. The increased demand is greatest in the northwest region and, if unchecked, would increase concerns there about the unsustainable use of groundwater. The growth in demand is determined particularly by growth in crop yields, population growth and the fraction of food demand satisfied by imports. An extreme hot-dry climate change scenario has a lesser impact. This suggests that, in principle, Bangladesh can offset the impacts of climate change on irrigation water demand through its domestic policies. Urban water use currently also leads to concerns over unsustainable groundwater use. Our results suggest that urban water demand is likely to grow proportionately significantly more than irrigation water demand. Alternative sources for urban water are therefore urgently required.
    MeSH term(s) Population Growth ; Climate Change ; Bangladesh ; Water ; Models, Theoretical ; Water Supply ; Growth and Development
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2022-12-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-26807-6
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  8. Article ; Online: Linking stress and inflammation - is there a missing piece in the puzzle?

    Pinhasov, Albert / Kirby, Michael

    Expert review of clinical immunology

    2022  Volume 18, Issue 4, Page(s) 321–323

    MeSH term(s) Brain ; Humans ; Hypothalamo-Hypophyseal System ; Inflammation ; Pituitary-Adrenal System
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Editorial
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2022.2052045
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6661: Show issues Location:
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  9. Article ; Online: Imaging in Asthma-Chronic Obstructive Pulmonary Disease Overlap.

    Svenningsen, Sarah / Kirby, Miranda

    Immunology and allergy clinics of North America

    2022  Volume 42, Issue 3, Page(s) 601–614

    Abstract: The purpose of this article is to review the imaging features in patients defined by researchers as having asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO), highlight the existing imaging studies investigating patients with ACO when ... ...

    Abstract The purpose of this article is to review the imaging features in patients defined by researchers as having asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO), highlight the existing imaging studies investigating patients with ACO when compared with those with asthma and COPD alone, and, finally, discuss some remaining gaps in the understanding of ACO that imaging may help resolve.
    MeSH term(s) Asthma/diagnosis ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnostic imaging
    Language English
    Publishing date 2022-06-30
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2022.04.003
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  10. Article ; Online: The Honourable Dr Donald James Grimes AO.

    Kirby, Michael / Warn, Patti

    The Medical journal of Australia

    2022  Volume 217, Issue 3, Page(s) 136–137

    Language English
    Publishing date 2022-07-11
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.51644
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