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  1. Article ; Online: A review of hair removal modalities in pediatric patients: Ethical and clinical considerations.

    Sanfilippo, Eric / Castelo-Soccio, Leslie / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2024  

    Abstract: Unwanted hair is a common concern among patients presenting to pediatric dermatology clinics, and parents and patients alike inquire about the safety of methods employed for elective removal. Various methods of hair removal exist with different levels of ...

    Abstract Unwanted hair is a common concern among patients presenting to pediatric dermatology clinics, and parents and patients alike inquire about the safety of methods employed for elective removal. Various methods of hair removal exist with different levels of invasiveness and permanence, from simple mechanical depilation to light-based therapies. All methods of hair removal appear to be safe and generally well tolerated in children, and there are no age restrictions to any modality. In this review, we aim to address the available literature on the safety and efficacy of hair removal modalities in pediatric patients and propose guidance on how to manage requests for at-home and in-office therapies within an ethical framework.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The future of iPLEDGE: We pledge for more inclusive access to isotretinoin.

    Shah, Nidhi / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2021  Volume 38 Suppl 2, Page(s) 183–184

    MeSH term(s) Acne Vulgaris/drug therapy ; Dermatologic Agents/therapeutic use ; Humans ; Isotretinoin
    Chemical Substances Dermatologic Agents ; Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2021-06-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Severe reactive infectious mucocutaneous eruption mimicking drug-induced epidermal necrolysis triggered by norovirus.

    Sanfilippo, Eric / Habeshian, Kaiane / Cotton, Colleen H / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2023  Volume 41, Issue 1, Page(s) 84–86

    Abstract: Reactive infectious mucocutaneous eruption (RIME) is an eruptive mucositis with varying degrees of cutaneous involvement presumed to be due to an immunologic response to various infectious pathogens. Most reported cases occur after a prodromal upper ... ...

    Abstract Reactive infectious mucocutaneous eruption (RIME) is an eruptive mucositis with varying degrees of cutaneous involvement presumed to be due to an immunologic response to various infectious pathogens. Most reported cases occur after a prodromal upper respiratory illness. We present a patient with a particularly severe case mimicking drug-induced epidermal necrolysis found to be triggered by asymptomatic norovirus infection, a virus not previously reported in association with RIME.
    MeSH term(s) Humans ; Norovirus ; Stevens-Johnson Syndrome/etiology ; Stevens-Johnson Syndrome/complications ; Mucositis/complications
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Case Reports
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Feeling the burn: Sunburn recall in staphylococcal scalded skin syndrome.

    Khanna, Rayva / Guo, Emily L / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2022  Volume 39, Issue 2, Page(s) 330–332

    Abstract: Staphylococcal scalded skin syndrome (SSSS) occurs primarily in infants and young children due to hematogenous dissemination of Staphylococcus aureus (S. aureus) exfoliative toxin resulting in painful erythema and superficial desquamation of the skin. ... ...

    Abstract Staphylococcal scalded skin syndrome (SSSS) occurs primarily in infants and young children due to hematogenous dissemination of Staphylococcus aureus (S. aureus) exfoliative toxin resulting in painful erythema and superficial desquamation of the skin. Herein, we discuss a 7-year-old patient with SSSS in classic locations who additionally presented with photodistributed erythema without desquamation on the chest, arms, and back in locations of a recently healed sunburn. In this report, we discuss sunburn recall phenomenon as a result of SSSS.
    MeSH term(s) Child ; Child, Preschool ; Humans ; Infant ; Skin ; Staphylococcal Scalded Skin Syndrome/diagnosis ; Staphylococcus aureus ; Sunburn/complications
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The utility of laboratory testing for pediatric patients undergoing isotretinoin treatment.

    Parthasarathy, Varsha / Shah, Nidhi / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2022  Volume 39, Issue 5, Page(s) 731–733

    Abstract: Isotretinoin, the most effective treatment for severe cystic acne, involves laboratory monitoring. In this retrospective case series of 130 pediatric patients taking isotretinoin, there were significant increases in cholesterol (143.9 mg/dl to 155.3 mg/ ... ...

    Abstract Isotretinoin, the most effective treatment for severe cystic acne, involves laboratory monitoring. In this retrospective case series of 130 pediatric patients taking isotretinoin, there were significant increases in cholesterol (143.9 mg/dl to 155.3 mg/dl), triglycerides (81.8 mg/dl to 115.2 mg/dl), and low-density lipoprotein (82.0 mg/dl to 98.1 mg/dl), and a decrease in high-density lipoprotein (50.0 mg/dl to 44.7 mg/dl) from baseline to follow-up (p < .05); there were no significant changes in liver enzymes. None of the patients had clinical sequelae (triglyceride-induced pancreatitis, retinoid-induced hepatotoxicity) related to their abnormal lab values. These findings question the utility of laboratory monitoring for prevention of severe clinical sequelae in pediatric patients, and suggest testing based on individualized risk factors may be more appropriate.
    MeSH term(s) Acne Vulgaris/drug therapy ; Child ; Cholesterol/therapeutic use ; Humans ; Isotretinoin/adverse effects ; Lipoproteins, HDL/therapeutic use ; Lipoproteins, LDL/therapeutic use ; Retrospective Studies ; Triglycerides/therapeutic use
    Chemical Substances Lipoproteins, HDL ; Lipoproteins, LDL ; Triglycerides ; Cholesterol (97C5T2UQ7J) ; Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2022-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exploring the costs associated with isotretinoin treatment.

    Shah, Nidhi / Byrne, Morgan / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2021  Volume 38, Issue 5, Page(s) 1396–1399

    Abstract: The multistep process to obtain an isotretinoin prescription under the iPLEDGE program is challenging for patients, particularly female patients. This retrospective study evaluates the differences in treatment and costs between male and female patients. ... ...

    Abstract The multistep process to obtain an isotretinoin prescription under the iPLEDGE program is challenging for patients, particularly female patients. This retrospective study evaluates the differences in treatment and costs between male and female patients. While male patients had a higher total cost of treatment than female patients, female patients had a higher treatment cost when medication costs were excluded. Female patients who missed prescription windows had a longer treatment course and incurred significantly higher treatment costs than female patients who did not miss a prescription window. The iPLEDGE program places female patients at a disadvantage of incurring higher treatment costs as a consequence of the prescription window requirement.
    MeSH term(s) Acne Vulgaris/drug therapy ; Dermatologic Agents/therapeutic use ; Female ; Humans ; Isotretinoin ; Male ; Retrospective Studies
    Chemical Substances Dermatologic Agents ; Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2021-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evaluating provider knowledge, perception, and concerns about cannabinoid use in pediatric dermatology.

    Shah, Nidhi / Kirkorian, Anna Yasmine / Friedman, Adam J

    Pediatric dermatology

    2021  Volume 38, Issue 3, Page(s) 694–696

    Abstract: As the use of medical cannabinoids expands, the value and acceptance in pediatric dermatology is poorly characterized. To better assess the current climate, this survey evaluated pediatric dermatologists' familiarity and knowledge about medical cannabis ... ...

    Abstract As the use of medical cannabinoids expands, the value and acceptance in pediatric dermatology is poorly characterized. To better assess the current climate, this survey evaluated pediatric dermatologists' familiarity and knowledge about medical cannabis and their interest to research and use cannabinoids. While the fund of knowledge and acceptance was high, providers voiced concerns about psychoactive effects of cannabis and substance abuse among their pediatric patients.
    MeSH term(s) Cannabinoids/adverse effects ; Cannabis ; Child ; Dermatology ; Humans ; Perception ; Surveys and Questionnaires
    Chemical Substances Cannabinoids
    Language English
    Publishing date 2021-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ecthyma gangrenosum: The critical role of biofilms and other mechanisms of antibiotic resistance and implications for management.

    Russomanno, Kristen / Cardis, Michael / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2021  Volume 38, Issue 2, Page(s) 458–460

    Abstract: Ecthyma gangrenosum is a rare cutaneous infection that occurs classically in immunocompromised patients with Pseudomonas aeruginosa bacteremia and is associated with a high mortality rate. Causative pathogens may exhibit various antibiotic evasion ... ...

    Abstract Ecthyma gangrenosum is a rare cutaneous infection that occurs classically in immunocompromised patients with Pseudomonas aeruginosa bacteremia and is associated with a high mortality rate. Causative pathogens may exhibit various antibiotic evasion mechanisms, and thus, treatment may be challenging. We present a case of ecthyma gangrenosum in association with an implantable port in which cultures confirmed ten unique strains of Pseudomonas aeruginosa, highlighting the ability of this pathogen to form biofilms, rapidly mutate and ultimately evade antibiotic therapy. Dermatologists play a key role in the prompt diagnosis of this life-threatening condition, and a thorough understanding of pathogenic mechanisms is critical in selecting an efficacious treatment regimen.
    MeSH term(s) Biofilms ; Drug Resistance, Microbial ; Ecthyma/diagnosis ; Ecthyma/drug therapy ; Humans ; Pseudomonas Infections/diagnosis ; Pseudomonas Infections/drug therapy ; Pseudomonas aeruginosa
    Language English
    Publishing date 2021-01-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ulcerated diaper dermatitis: Child abuse mimicker.

    Caldas, Stella A / Murphy, Emily / Habeshian, Kaiane / Kirkorian, Anna Yasmine / Hinds, Tanya

    Pediatric dermatology

    2023  Volume 41, Issue 1, Page(s) 87–90

    Abstract: Irritant diaper dermatitis is a common dermatologic problem among infants and young children. Severe erosive presentations, although uncommon, are diagnostically challenging and can mimic non-accidental trauma (NAT). Diagnosing inflicted injury and NAT ... ...

    Abstract Irritant diaper dermatitis is a common dermatologic problem among infants and young children. Severe erosive presentations, although uncommon, are diagnostically challenging and can mimic non-accidental trauma (NAT). Diagnosing inflicted injury and NAT where it does not exist can cause parental distress, yet failing to diagnose inflicted injury and NAT can result in re-injury. We describe three cases of severe erosive diaper dermatitis in pediatric patients aged 2-6 years that were initially concerning for inflicted scald burn or neglect.
    MeSH term(s) Infant ; Humans ; Child ; Child, Preschool ; Diaper Rash/diagnosis ; Diaper Rash/etiology ; Burns/complications ; Child Abuse/diagnosis ; Diagnosis, Differential ; Parents
    Language English
    Publishing date 2023-06-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Giant Cutaneous Horn Arising in an Epidermal Nevus.

    Cardis, Michael A / Kirkorian, Anna Yasmine

    Pediatric dermatology

    2017  Volume 34, Issue 5, Page(s) e290–e291

    Abstract: Cutaneous horns, which rarely occur in children, can overlie a large array of pathologic lesions that range from benign to malignant. When a cutaneous horn is encountered, it is not the horn itself that is of relevance, it is the nature of the underlying ...

    Abstract Cutaneous horns, which rarely occur in children, can overlie a large array of pathologic lesions that range from benign to malignant. When a cutaneous horn is encountered, it is not the horn itself that is of relevance, it is the nature of the underlying disease that dictates overall prognosis and management. In this report we present a case of a cutaneous horn arising within a linear verrucous epidermal nevus and briefly review cutaneous horns, with an emphasis on their clinical implications and differential diagnosis.
    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.13221
    Database MEDical Literature Analysis and Retrieval System OnLINE

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