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Article: Platysmal Myocutaneous Flap for Intra Oral Defects:Is It an Underutilized Option? Our Experience of 10 Cases.

Sahni, Manish / Singh, Suresh / Kishor, Kamal / Patel, Pinakin / Sharma, Rajgovind

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2023 Volume 75, Issue 4, Page(s) 3581–3584

Abstract: Various methods of reconstruction are available for reconstructing oral cancer defects, but all of them have their inherent drawbacks. The superiorly based platysma myocutaneous flap is a common reconstruction option for intra-oral defects following oral ...

Abstract	Various methods of reconstruction are available for reconstructing oral cancer defects, but all of them have their inherent drawbacks. The superiorly based platysma myocutaneous flap is a common reconstruction option for intra-oral defects following oral cancer resections. We present our results of using platysmal flaps in reconstructing intraoral defects following oral cavity cancer resection in our 7 patients along with resection of three cases of premalignant conditions of oral cavity. All the patients were males of age ranging from 24 to 42 years and diagnosed as squamous cell carcinoma of oral cavity stage I and II were included in this study.Of 10 patients eight had no postoperative complications. One patient developed partial skin loss of neck donor site, which was managed conservatively. Other patient had complete flap loss which healed with secondary intention. We recommend this flap as incision is always away from the face, the scars are hidden beneath collars and the patients are very comfortable with good cosmetics and functional outcomes.\.
Language	English
Publishing date	2023-07-10
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-023-04055-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Sarcopenic Obesity as a Risk Factor for Cardiovascular Disease: An Underrecognized Clinical Entity.

Binu, Aditya John / Kapoor, Nitin / Bhattacharya, Saptarshi / Kishor, Kamal / Kalra, Sanjay

Heart international

2023 Volume 17, Issue 2, Page(s) 6–11

Abstract: Sarcopenic obesity (SO) is a chronic condition and an emerging health challenge, in view of the growing elderly population and the obesity epidemic. Due to a lack of awareness among treating doctors and the non-specific nauture of the associated symptoms, ...

Abstract	Sarcopenic obesity (SO) is a chronic condition and an emerging health challenge, in view of the growing elderly population and the obesity epidemic. Due to a lack of awareness among treating doctors and the non-specific nauture of the associated symptoms, SO remains grossly underdiagnosed. There is no consensus yet on a standard definition or diagnostic criteria for SO, which limits the estimation of the global prevalence of this condition. It has been linked to numerous metabolic derangements, cardiovascular disease (CVD) and mortality. The treatment of SO is multimodal and requires expertise across multiple specialties. While dietary modifications and exercise regimens have shown a potential therapeutic benefit, there is currently no proven pharmacological management for SO. However, numerous drugs and the role of bariatric surgery are still under trial, and have great scope for further research. This article covers the available literature regarding the definition, diagnostic criteria, and prevalence of SO, with available evidence linking it to CVD, metabolic disease and mortality, and an overview of current directives on management.
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2514156-9
ISSN	2036-2579 ; 2036-2579
ISSN (online)	2036-2579
ISSN	2036-2579
DOI	10.17925/HI.2023.17.2.6
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Article: Screening for heart failure in diabetes.

Kalra, Sanjay / Punyani, Hitesh / Kishor, Kamal

JPMA. The Journal of the Pakistan Medical Association

2021 Volume 70, Issue 12(A), Page(s) 2289–2290

Abstract: Heart failure (HF) is an important, yet under recognized and under diagnosed complication of diabetes. This communication describes the clinical features of heart failure, and shares a validated tool which helps identify HF. This information will be of ... ...

Abstract	Heart failure (HF) is an important, yet under recognized and under diagnosed complication of diabetes. This communication describes the clinical features of heart failure, and shares a validated tool which helps identify HF. This information will be of help to all health care professionals, especially those who work in primary care settings with minimal access to advanced imaging and biochemical investigations.
MeSH term(s)	Biomarkers ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/epidemiology ; Heart Failure/diagnosis ; Heart Failure/etiology ; Humans ; Mass Screening ; Natriuretic Peptide, Brain ; Peptide Fragments ; Stroke Volume
Chemical Substances	Biomarkers ; Peptide Fragments ; Natriuretic Peptide, Brain (114471-18-0)
Language	English
Publishing date	2021-01-21
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
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Article: Anginal Equivalents: As simple as ABCDE.

Kalra, Sanjay / Kishor, Kamal

JPMA. The Journal of the Pakistan Medical Association

2019 Volume 69, Issue 5, Page(s) 747–748

Abstract: This communication highlights the concept of angina equivalents as an important symptom of cardiovasculardisease in diabetes. The authors share two mnemonics, as simple as ABCDE, which can help identify atypical cardiovascular disease. Use of these ... ...

Abstract	This communication highlights the concept of angina equivalents as an important symptom of cardiovasculardisease in diabetes. The authors share two mnemonics, as simple as ABCDE, which can help identify atypical cardiovascular disease. Use of these learning tools should help improve early detection and management of cardiovascular disease.
MeSH term(s)	Acute Coronary Syndrome/diagnosis ; Acute Disease ; Angina Pectoris/diagnosis ; Cardiovascular Diseases/diagnosis ; Chronic Disease ; Diabetes Complications/diagnosis ; Diabetes Mellitus ; Humans ; Myocardial Ischemia/diagnosis
Language	English
Publishing date	2019-05-20
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
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Article: Sources, spatio-temporal distribution and depth variations in groundwater salinity of semi-arid Rohtak district, Haryana, India

Kishor, Kamal / Patel, Manvendra / Bhattacharya, Prosun / Pittman, Charles U. / Mohan, Dinesh

Groundwater for sustainable development. 2022 May 21,

2022

Abstract: Groundwater salinity problem was evaluated in the Rohtak district of the state of Haryana in northwestern India. The groundwater samples were collected from 82 villages of the district. Both post-monsoon and pre-monsoon samplings were carried out for two ...

Abstract	Groundwater salinity problem was evaluated in the Rohtak district of the state of Haryana in northwestern India. The groundwater samples were collected from 82 villages of the district. Both post-monsoon and pre-monsoon samplings were carried out for two consecutive years (2017–2019). A total of 620 samples in the four seasons (155 in each season) were collected under strict QAs and QCs from APHA. The co-existing hydro-chemical parameters of salinity, total dissolved solids (TDS) and electrical conductivity (EC) were determined. ArcGIS 10.5 was used for spatiotemporal distribution evaluation. Groundwater salinity values between 0.20 and 8.00 parts per thousand (ppt) were obtained. Hand pump water is more saline (0.3–7.5 ppt) than bore-well (0.2–1.8 ppt) and dug-well water (0.6–1.3 ppt), thus limiting the options for viable water sources. Higher groundwater salinity in the post-monsoon season as compared to pre-monsoon season was observed. Groundwater salinity in the Rohtak district decreases in the order: Lakhan-Majra < Meham < Rohtak < Sampla < Kalanaur. Safer groundwater salinity levels were found in deep bore wells (>20 m) versus shallow bore wells (<20 m). Thus, this study evaluates the spatio-temporal and depth variations in groundwater salinity of Rohtak district. At the end the study proposes possible remedial measures for salinity problems.
Keywords	groundwater ; sustainable development ; water salinity ; India
Language	English
Dates of publication	2022-0521
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ISSN	2352-801X
DOI	10.1016/j.gsd.2022.100790
Database	NAL-Catalogue (AGRICOLA)

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Article: Cardiovigilance in COVID 19.

Kishor, Kamal / Marwah, Rishabh / Anantharaj, Avinash / Kalra, Sanjay

JPMA. The Journal of the Pakistan Medical Association

2020 Volume 70Suppl 3, Issue 5, Page(s) S77–S80

Abstract: The COVID19 (Corona Virus Disease: pandemic started in 2019) pandemic has created not only a public health problem, but as a clinical challenge as well. To the cardiologist, COVID 19 presents a wide spectrum of possibilities for clinical decision-making ... ...

Abstract	The COVID19 (Corona Virus Disease: pandemic started in 2019) pandemic has created not only a public health problem, but as a clinical challenge as well. To the cardiologist, COVID 19 presents a wide spectrum of possibilities for clinical decision-making intervention and improvement. Cardiac dysfunction has been identified as a risk factor, a prognostic factor, a diagnostic tool, differential diagnosis, a complication of COVID 19, and a side effect of its treatment. Certain cardiotropic drugs have been implicated in the pathogenesis of COVID 19. The risk of transmission of COVID 19 is an occupational hazard which cannot be ignored by cardiologists. This review discusses the need and scope of cardio vigilance in COVID 19 management.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Clinical Decision-Making ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Heart Diseases/complications ; Heart Diseases/drug therapy ; Heart Diseases/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Risk Factors ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-06-09
Publishing country	Pakistan
Document type	Journal Article ; Review
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
DOI	10.5455/JPMA.14
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Article: Depolarized Mitochondrial Membrane Potential and Elevated Calcium in Platelets of Sickle Cell Disease.

Maharana, Samarjit / Roy, Chitrali Laha / Kishor, Kamal / Ranjan, Ravi / Ahmad, Firdos / Mahapatra, Manoranjan / Saxena, Renu / Kannan, Meganathan

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

2023 Volume 39, Issue 4, Page(s) 565–571

Abstract: Hemolysis, a crucial feature of Sickle cell disease (SCD), is a key player for cellular activation leading to various complications including thrombosis. In response to hemolysis, platelets get activated and release components that are necessary for ... ...

Abstract	Hemolysis, a crucial feature of Sickle cell disease (SCD), is a key player for cellular activation leading to various complications including thrombosis. In response to hemolysis, platelets get activated and release components that are necessary for further platelet activation and aggregation. Thus, it is believed that platelets contribute to the development of thrombotic complications. Platelets in SCD are expected to be affected due to common cause of hemolysis. To measure the surface markers of platelets including P-Selectin, Phosphatidyl Serine and integrin αIIbβ3 in SCD patients and healthy controls in order to understand the status of the platelets in SCD. To measure the surface markers of activated platelets using flow cytometry. Since mitochondria and calcium play an important role in cellular functions, the mitochondrial membrane potential and calcium content of platelets in SCD were also evaluated using flow cytometry. In the present study, we have observed significant increase of calcium level in SCD platelets. Further, the loss of mitochondrial membrane potential in SCD platelets was found to be significantly higher when compared to platelets of healthy controls. Though the surface markers of activated platelets in SCD remain unchanged, increased level of calcium and mitochondrial membrane potential loss suggest that the platelets in SCD are more prone to become activated. In order to understand the status of the platelets in SCD, apart from the surface markers, it is also important to assess the calcium levels and mitochondrial membrane potential of platelets.
Language	English
Publishing date	2023-03-04
Publishing country	India
Document type	Journal Article
ZDB-ID	2422370-0
ISSN	0974-0449 ; 0971-4502
ISSN (online)	0974-0449
ISSN	0971-4502
DOI	10.1007/s12288-023-01640-7
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Article: Atrial fibrillation: The endocrine connection.

Kalra, Sanjay / Kishor, Kamal / Khandelwal, Deepak

JPMA. The Journal of the Pakistan Medical Association

2019 Volume 69, Issue 11, Page(s) 1746–1749

Abstract: Atrial fibrillation (AF) is the most commonly encountered arrhythmia in cardiology practice. A diagnosis of AF implies a greater need for hospitalization, a higher risk of stroke and heart failure, and earlier mortality. These complications can be ... ...

Abstract	Atrial fibrillation (AF) is the most commonly encountered arrhythmia in cardiology practice. A diagnosis of AF implies a greater need for hospitalization, a higher risk of stroke and heart failure, and earlier mortality. These complications can be avoided if AF is diagnosed and treated in a timely manner. To achieve this, physicians need to maintain a high index of clinical suspicion, practice cardiovigilance, and screen for AF in appropriate clinical settings. This review describes the vast spectrum of endocrine and metabolic disease that are associated with AF. Through this perspective, it encourages physicians and endocrinologists to play an active role in AF detection, referral and long term management.
MeSH term(s)	Atrial Fibrillation/etiology ; Atrial Fibrillation/physiopathology ; Endocrine System Diseases/complications ; Endocrine System Diseases/physiopathology ; Gonadal Steroid Hormones ; Humans ; Risk Factors ; Vitamin D
Chemical Substances	Gonadal Steroid Hormones ; Vitamin D (1406-16-2)
Language	English
Publishing date	2019-11-19
Publishing country	Pakistan
Document type	Journal Article ; Review
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
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Article: Atrial fibillation in diabetes: Need for cardiovigilance.

Kalra, Sanjay / Kishor, Kamal / Batra, Aditya / Aggarwal, Sameer

JPMA. The Journal of the Pakistan Medical Association

2019 Volume 69, Issue 3, Page(s) 437–439

Abstract: Atrial fibrillation (AF), the commonest arrhythmia in clinical practice, is also the commonest arrhythmia for which hospitalization is required. AF is associated with a 5 fold increase in stroke, a 2 fold increase in all-cause mortality, and a higher ... ...

Abstract	Atrial fibrillation (AF), the commonest arrhythmia in clinical practice, is also the commonest arrhythmia for which hospitalization is required. AF is associated with a 5 fold increase in stroke, a 2 fold increase in all-cause mortality, and a higher risk of heart failure. Hence, it is imperative to focus on the risk factors and clinical features of this condition, so that it can be prevented and managed in a timely manner. AF is linked with multiple metabolic and endocrine morbidities. This implies that the endocrinologist has an important role to play in AF detection and referral. This review, the first of a two part series, encourages preventive cardiovigilance, and especially electro-cardiovigilance, in diabetes practice.
MeSH term(s)	Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/prevention & control ; Diabetes Mellitus ; Disease Management ; Electrocardiography ; Electrocardiography, Ambulatory ; Humans ; Stroke/etiology ; Stroke/prevention & control
Chemical Substances	Anticoagulants
Language	English
Publishing date	2019-03-19
Publishing country	Pakistan
Document type	Journal Article ; Review
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
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Article: Cardiovigilance in COVID 19

Kishor, Kamal / Marwah, Rishabh / Anantharaj, Avinash / Kalra, Sanjay

J Pak Med Assoc

Abstract	The COVID19 (Corona Virus Disease: pandemic started in 2019) pandemic has created not only a public health problem, but as a clinical challenge as well. To the cardiologist, COVID 19 presents a wide spectrum of possibilities for clinical decision-making intervention and improvement. Cardiac dysfunction has been identified as a risk factor, a prognostic factor, a diagnostic tool, differential diagnosis, a complication of COVID 19, and a side effect of its treatment. Certain cardiotropic drugs have been implicated in the pathogenesis of COVID 19. The risk of transmission of COVID 19 is an occupational hazard which cannot be ignored by cardiologists. This review discusses the need and scope of cardio vigilance in COVID 19 management.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32515382
Database	COVID19

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