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  1. Artikel ; Online: Recurrent tumefactive demyelination under fingolimod treatment.

    İriş, Merve / Kızılkılıç, Osman / Saip, Sabahattin / Uygunoğlu, Uğur

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2024  Band 45, Heft 5, Seite(n) 2377–2378

    Mesh-Begriff(e) Humans ; Fingolimod Hydrochloride/adverse effects ; Multiple Sclerosis/drug therapy ; Brain Neoplasms/drug therapy ; Magnetic Resonance Imaging
    Chemische Substanzen Fingolimod Hydrochloride (G926EC510T)
    Sprache Englisch
    Erscheinungsdatum 2024-01-15
    Erscheinungsland Italy
    Dokumenttyp Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-024-07310-4
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  2. Artikel ; Online: Unusual collaterals through interhemispheric connections in Moyamoya disease

    Bağcılar, Ömer / Korkmazer, Bora / Kızılkılıç, Osman / Işlak, Civan

    Diagnostic and interventional radiology (Ankara, Turkey)

    2023  Band 30, Heft 1, Seite(n) 72–73

    Mesh-Begriff(e) Humans ; Moyamoya Disease/diagnostic imaging ; Collateral Circulation ; Cerebral Angiography
    Sprache Englisch
    Erscheinungsdatum 2023-04-05
    Erscheinungsland Turkey
    Dokumenttyp Journal Article
    ZDB-ID 2184145-7
    ISSN 1305-3612 ; 1305-3612
    ISSN (online) 1305-3612
    ISSN 1305-3612
    DOI 10.4274/dir.2023.232140
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Delayed Enhancing White Matter Lesions, a Rare Complication After Stent-Assisted Coil Embolization: A Case Report.

    Kochan Kizilkilic, Esra / Unkun, Rumeysa / Karadeniz, Kağan Gökdeniz / Korkmazer, Bora / Kizilkilic, Osman / Delil, Sakir

    World neurosurgery

    2024  Band 187, Seite(n) 42–45

    Abstract: Background: Delayed enhancing white matter lesions are a rare complication that develops after endovascular treatment of cerebral aneurysms, the etiology of which remains unclear.: Methods and results: We present a 52-year-old female patient who was ... ...

    Abstract Background: Delayed enhancing white matter lesions are a rare complication that develops after endovascular treatment of cerebral aneurysms, the etiology of which remains unclear.
    Methods and results: We present a 52-year-old female patient who was symptomatic with a seizure-like condition and showed reversible cranial parenchymal changes with high-dose cortisone treatment after endovascular stent-assisted coil embolization for an unruptured aneurysm in the internal cerebral artery.
    Conclusions: Clinicians should be alert to this rare complication and should follow patients for a long time due to its fluctuating and long-term course.
    Sprache Englisch
    Erscheinungsdatum 2024-03-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2024.03.110
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  4. Artikel ; Online: Evaluation of short- and long-term results of Y-stent-assisted coiling with Leo stents in endovascular treatment of wide-necked intracranial bifurcation aneurysms.

    Suleyman, Kanullah / Korkmazer, Bora / Kocer, Naci / Islak, Civan / Kızılkılıc, Osman

    Neuroradiology

    2023  Band 65, Heft 4, Seite(n) 785–791

    Abstract: Purpose: This study aimed to evaluate the feasibility, safety, and efficacy of Y-stent-assisted coiling (Y-SAC) using LEO Baby® stents in treating of bifurcation aneurysms.: Methods: Patients who underwent Y-SAC using a braided stent (LEO Baby®, ... ...

    Abstract Purpose: This study aimed to evaluate the feasibility, safety, and efficacy of Y-stent-assisted coiling (Y-SAC) using LEO Baby® stents in treating of bifurcation aneurysms.
    Methods: Patients who underwent Y-SAC using a braided stent (LEO Baby®, Montmorency, France) for wide-necked intracranial aneurysms between 2009 and 2019 and whose radiological and clinical follow-up data for at least 6 months could be obtained were evaluated. Data were obtained from patient records and analyzed retrospectively.
    Results: We evaluated 111 patients with a mean age of 56.0 ± 10.8 years (range, 25-88 years). Most of the aneurysms were detected incidentally. Three patients had ruptured aneurysms. LEO Baby deployment and coiling were successful in all patients. Immediate aneurysm occlusion rates were determined as modified Raymond-Roy classification (mRRC) I 95.5% (n = 106), mRRC II 3.6% (n = 4), mRRC IIIa 0.9% (n = 1). In the sixth month, aneurysm occlusion rates were found to be complete and nearly complete in all patients (mRRC I 94.6%, n = 105 and mRRC II 4.5%; n = 5, respectively). Follow-up data of 91 patients for > 2 years were obtained. Of these, 88 had MRRCI obstruction and 3 had MRRC II obstruction. The overall complication rate was 4.8%, and one patient died during the post-procedural follow-up.
    Conclusion: The long-term follow-up results of Y-stenting with LEO Baby revealed that it provides stable closure of the aneurysm sac while preserving the main arterial structures. Therefore, it is a safe, durable, and effective method for treating wide-necked and complex bifurcation aneurysms.
    Mesh-Begriff(e) Intracranial Aneurysm/surgery ; Stents ; Endovascular Aneurysm Repair ; Humans ; Male ; Female ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Embolization, Therapeutic ; Treatment Outcome ; Turkey
    Sprache Englisch
    Erscheinungsdatum 2023-01-18
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 123305-1
    ISSN 1432-1920 ; 0028-3940
    ISSN (online) 1432-1920
    ISSN 0028-3940
    DOI 10.1007/s00234-023-03116-x
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  5. Artikel ; Online: Trigeminal neuropathy as presenting symptom of craniofacial venous metameric syndrome.

    Ser, Merve H / Kalındemirtaş, Celal / Kızılkılıç, Osman / Uygunoğlu, Uğur

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2022  Band 43, Heft 10, Seite(n) 6155–6157

    Abstract: Aims: Trigeminal neuropathy is more likely to suggest neuronal damage and occur due to secondary pathology than trigeminal neuralgia. Evaluation of underlying etiologies are necessary.: Case: A 29-year-old female patient presented with left sided ... ...

    Abstract Aims: Trigeminal neuropathy is more likely to suggest neuronal damage and occur due to secondary pathology than trigeminal neuralgia. Evaluation of underlying etiologies are necessary.
    Case: A 29-year-old female patient presented with left sided continuous burning pain likened to pins and needles at maxillary distribution for about a year. Her examination was normal except left-sided buccal swelling without any skin or mucosal change. Cranial MRI revealed asymmetrical dilation of left Meckel's cave, bilateral cerebral developmental venous anomaly and left sided slow flow venous malformation from superior temporal fossa to masseter muscle. Cerebral angiography confirmed widespread venous return anomaly in both cerebral hemispheres and slow-flow venous malformation that does not fill in the early arterial phase in the left buccal space and superficial temporal fossa. Cerebrofacial venous metameric syndrome is diagnosed. Percutaneous sclerotherapy with alcohol is planned in three separate sessions, the first of the three planned sessions is performed yet and the patient stated that her neuropathic pain decreased by 40% afterwards.
    Significance: Clinical manifestation of the cerebrofacial venous metameric syndrome depends on the localization of the lesions; therefore, venous anomalies in relation with the trigeminal branches can present with painful trigeminal neuropathy.
    Mesh-Begriff(e) Adult ; Female ; Humans ; Magnetic Resonance Imaging/adverse effects ; Trigeminal Nerve Diseases/diagnostic imaging ; Trigeminal Nerve Diseases/etiology ; Trigeminal Neuralgia/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2022-06-13
    Erscheinungsland Italy
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-06179-5
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  6. Artikel ; Online: A new ventricular index based on coronal brain magnetic resonance images in patients with idiopathic normal pressure hydrocephalus.

    Yılmazsoy, Yunus / Arslan, Serdar / Özdemir, Adnan / Korkmazer, Bora / Kızılkılıç, Osman / Kafadar, Ali Metin

    Turkish journal of medical sciences

    2023  Band 53, Heft 1, Seite(n) 282–288

    Abstract: Background: The aim of this study was to assess the effectiveness of a new quantitative index for the diagnosis of idiopathic normal pressure hydrocephalus.: Methods: This retrospective study was conducted at İstanbul University Cerrahpaşa Medical ... ...

    Abstract Background: The aim of this study was to assess the effectiveness of a new quantitative index for the diagnosis of idiopathic normal pressure hydrocephalus.
    Methods: This retrospective study was conducted at İstanbul University Cerrahpaşa Medical Faculty between January 2016 and November 2022. A total of 31 patients diagnosed with idiopathic normal pressure hydrocephalus were included in the study group and 48 patients were included in the control group. Measurement via the new Index was performed on a coronal section of magnetic resonance imaging at the level of the anterior commissure.
    Results: The new Index's mean diagnostic performance was 1.16 ± 0.08 in the study group, significantly lower (p < 0.0001) than the mean of 1.43 ± 0.10 in the control group. When a cutoff value of 1.23 was used for the new index, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rates were 96.1%, 90.7%, 80.6%, 98%, and 91.3%, respectively.
    Discussion: The new Index described here is an effective, feasible, reproducible, highly sensitive, and specific quantitative method that can contribute to the improved diagnosis of patients with idiopathic normal pressure hydrocephalus.
    Mesh-Begriff(e) Humans ; Hydrocephalus, Normal Pressure/diagnostic imaging ; Retrospective Studies ; Subarachnoid Space/pathology ; Magnetic Resonance Imaging/methods ; Brain/pathology
    Sprache Englisch
    Erscheinungsdatum 2023-02-22
    Erscheinungsland Turkey
    Dokumenttyp Journal Article
    ZDB-ID 1183461-4
    ISSN 1303-6165 ; 1300-0144
    ISSN (online) 1303-6165
    ISSN 1300-0144
    DOI 10.55730/1300-0144.5583
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Intracranial vessel wall imaging.

    Arslan, Serdar / Korkmazer, Bora / Kizilkilic, Osman

    Current opinion in rheumatology

    2020  Band 33, Heft 1, Seite(n) 41–48

    Abstract: Purpose of review: To give an overview regarding the potential usefulness of vessel wall imaging (VWI) in distinguishing various intracranial vascular diseases, their common imaging features, and potential pitfalls.: Recent findings: VWI provides ... ...

    Abstract Purpose of review: To give an overview regarding the potential usefulness of vessel wall imaging (VWI) in distinguishing various intracranial vascular diseases, their common imaging features, and potential pitfalls.
    Recent findings: VWI provides direct visualization of the vessel wall and allows the discrimination of different diseases such as vasculitis, atherosclerosis, dissection, Moyamoya disease, and reversible cerebral vasoconstriction syndrome. Recent studies showed that concentric and eccentric involvement in the vessel wall, as well as the enhancement pattern were found important for the distinguishing these diseases and evaluating their activity.
    Summary: Most of the imaging techniques currently used are based on luminal imaging. However, these imaging methods are not adequate to distinguish different diseases that can demonstrate similar radiological findings. VWI is being increasingly used as a noninvasive imaging method to offset this limitation.
    Mesh-Begriff(e) Adult ; Aged ; Atherosclerosis/diagnostic imaging ; Cerebrovascular Disorders/diagnostic imaging ; Child ; Female ; Humans ; Magnetic Resonance Angiography/methods ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Moyamoya Disease/diagnostic imaging ; Vasculitis/diagnostic imaging ; Vasculitis, Central Nervous System/diagnostic imaging
    Sprache Englisch
    Erscheinungsdatum 2020-11-13
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1045317-9
    ISSN 1531-6963 ; 1040-8711
    ISSN (online) 1531-6963
    ISSN 1040-8711
    DOI 10.1097/BOR.0000000000000759
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Superselective intra-arterial chemotherapy treatment for retinoblastoma: clinical experience from a tertiary referral centre.

    Batu Oto, Bilge / Sarıcı, Ahmet Murat / Kızılkılıç, Osman

    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

    2020  Band 55, Heft 5, Seite(n) 406–412

    Abstract: Objective: To evaluate the treatment outcomes of an alternative retrograde superselective ophthalmic artery catheterization (intra-arterial chemotherapy [IAC]), while treating retinoblastoma patients.: Methods: A retrospective review of IAC for 21 ... ...

    Abstract Objective: To evaluate the treatment outcomes of an alternative retrograde superselective ophthalmic artery catheterization (intra-arterial chemotherapy [IAC]), while treating retinoblastoma patients.
    Methods: A retrospective review of IAC for 21 treatment-naïve eyes (21 patients, primary group) and 10 eyes of previously treated 9 patients (secondary group). Statistical analysis was performed using Number Cruncher Statistical System 2007, Kaplan-Meier survival analysis, and Fisher's exact test.
    Results: Total fluoroscopy time ranged from 3 to 12 minutes. Globe salvage was 71.4% (15/21 eyes) and 80% (8/10 eyes) in the primary and secondary groups, respectively. Globe salvage rates were recorded as 100%, 100%, 70%, and 0% for group B, C, D, and E patients, respectively.
    Conclusions: Retrograde IAC is effective in tumour control with shorter fluoroscopy time and acceptable complication rates both for naïve and treated patients. Furthermore, controlling retinoblastoma in advanced group D eyes was efficacious.
    Mesh-Begriff(e) Humans ; Infant ; Infusions, Intra-Arterial ; Melphalan/therapeutic use ; Retinal Neoplasms/diagnosis ; Retinal Neoplasms/drug therapy ; Retinoblastoma/drug therapy ; Retrospective Studies ; Tertiary Care Centers
    Chemische Substanzen Melphalan (Q41OR9510P)
    Sprache Englisch
    Erscheinungsdatum 2020-06-08
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 80091-0
    ISSN 1715-3360 ; 0008-4182
    ISSN (online) 1715-3360
    ISSN 0008-4182
    DOI 10.1016/j.jcjo.2020.04.009
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  9. Artikel ; Online: Lacrimal gland enlargement and tear film changes in acromegaly patients: A controlled study.

    Mergen, Burak / Arici, Ceyhun / Kizilkilic, Osman / Tanriover, Necmettin / Kadioglu, Pinar

    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

    2021  Band 59, Seite(n) 101397

    Abstract: Purpose: Evaluation of the lacrimal gland volume (LGV) and its correlation with tear film functions, serum growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels in acromegaly patients compared to a control group was aimed.: Methods: ... ...

    Abstract Purpose: Evaluation of the lacrimal gland volume (LGV) and its correlation with tear film functions, serum growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels in acromegaly patients compared to a control group was aimed.
    Methods: This prospective case-control study included the eyes of 38 patients with uncontrolled (UA) and 48 patients with controlled acromegaly (CA) and 44 patients with nonfunctioning pituitary adenoma. LGV of the patients was evaluated at the baseline, 3rd, and 6th-month visits with magnetic resonance imaging. Schirmer's test, tear breakup time (TBUT), and ocular surface disease index (OSDI) scores were evaluated at the same visits. Their correlation with serum IGF-1 and GH was investigated. Main outcome measure was the difference in mean LGV.
    Results: The mean LGV of the acromegaly patients at the baseline visit (116.0 ± 33.2 mm
    Conclusion: Acromegaly patients may have larger lacrimal glands compared to the controls and this increase correlated with the increased IGF-1 and GH levels. Lacrimal gland volume may have no effect on its tear film related functions.
    Mesh-Begriff(e) Acromegaly/physiopathology ; Biomarkers/blood ; Case-Control Studies ; Female ; Follow-Up Studies ; Human Growth Hormone/blood ; Humans ; Insulin-Like Growth Factor I/analysis ; Lacrimal Apparatus/pathology ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Tears/chemistry
    Chemische Substanzen Biomarkers ; IGF1 protein, human ; Human Growth Hormone (12629-01-5) ; Insulin-Like Growth Factor I (67763-96-6)
    Sprache Englisch
    Erscheinungsdatum 2021-05-11
    Erscheinungsland Scotland
    Dokumenttyp Journal Article
    ZDB-ID 1436781-6
    ISSN 1532-2238 ; 1096-6374
    ISSN (online) 1532-2238
    ISSN 1096-6374
    DOI 10.1016/j.ghir.2021.101397
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  10. Artikel ; Online: Spontaneous internal carotid artery dissection in a child diagnosed by high resolution vessel wall MRI.

    Karaman, Ahmet Kursat / Korkmazer, Bora / Arslan, Serdar / Kızılkılıç, Osman / Koçer, Naci / Islak, Civan

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2022  Band 39, Heft 4, Seite(n) 1101–1105

    Abstract: Craniocervical dissection is one of the most common causes of stroke in children. Although the most common cause of dissection is trauma, spontaneous dissections in which no cause can be revealed may also occur. The diagnosis of this type of dissection ... ...

    Abstract Craniocervical dissection is one of the most common causes of stroke in children. Although the most common cause of dissection is trauma, spontaneous dissections in which no cause can be revealed may also occur. The diagnosis of this type of dissection in children can be challenging with the preferred non-invasive imaging methods (MRA, CTA). Intracranial vessel wall imaging is a promising novel method for identifying specific signs of dissection. We report an 11-year-old girl with spontaneous ICA dissection, whose diagnosis was confirmed by an MRI of the intracranial vessel wall. Vessel wall imaging has contributed substantially to the diagnosis and follow-up of this case.
    Mesh-Begriff(e) Female ; Humans ; Child ; Carotid Artery, Internal, Dissection/diagnostic imaging ; Carotid Artery, Internal, Dissection/complications ; Carotid Artery, Internal ; Magnetic Resonance Imaging/methods ; Stroke/etiology
    Sprache Englisch
    Erscheinungsdatum 2022-11-11
    Erscheinungsland Germany
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-022-05745-8
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