Article ; Online: Impact of Body Mass Index on Complications and Survival after Surgery for Esophageal and Gastro-Esophageal-Junction Cancer.
2017 Volume 106, Issue 4, Page(s) 305–310
Abstract: Background and aims: The impact of body mass index on complications and survival in patients undergoing esophagectomy has been extensively studied with conflicting results. In this study, we assess the impact of body mass index on complications and ... ...
| Abstract | Background and aims: The impact of body mass index on complications and survival in patients undergoing esophagectomy has been extensively studied with conflicting results. In this study, we assess the impact of body mass index on complications and survival following surgery for esophageal and gastro-esophageal-junction cancer in a Danish population. Material and methods: We identified 285 consecutive patients, who underwent curative-intended treatment for esophageal and gastro-esophageal-junction cancer in the period 2003-2010. We manually reviewed the electronic medical records of all patients included in the study. Body mass index was calculated as weight in kilograms divided by height in meters squared. We grouped patients according to their body mass index, using the World Health Organization definition, as underweight (body mass index < 18.5 kg/m Results: Median age at surgery was 65 years (range: 27-84 years), of which 207 (72.6%) were males. Patients with the lowest body mass index and the obese patients seemed to have a higher frequency of minor complications. Anastomotic leakage occurred in less than 10% of the patients and was equally distributed across the groups as was the other major complications. There were no differences in the 1-, 2-, or 5-year survival rates between the four body mass index groups after adjustment for possible confounders. Five-year survival rates for the four body mass index groups were 31.8%, 28.7%, 27.9%, and 26.1%, respectively. Conclusion: Body mass index over 30 or under 18.5 does not seem to affect survival rates or the presence of serious postoperative complications following esophagectomy in patients with esophageal and gastro-esophageal-junction cancers not receiving neoadjuvant oncological treatment. |
|---|---|
| MeSH term(s) | Adenocarcinoma/mortality ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/surgery ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/surgery ; Esophagectomy/mortality ; Esophagogastric Junction/surgery ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Overweight/complications ; Overweight/diagnosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Retrospective Studies ; Risk Factors ; Stomach Neoplasms/mortality ; Stomach Neoplasms/surgery ; Treatment Outcome |
| Language | English |
| Publishing date | 2017-12 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2077691-3 |
| ISSN | 1799-7267 ; 1457-4969 |
| ISSN (online) | 1799-7267 |
| ISSN | 1457-4969 |
| DOI | 10.1177/1457496916683097 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Uk I Zs.224: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.