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  1. Book: Drug therapy supplement

    Kjeldsen, Sverre E.

    (Blood pressure ; 19, Suppl. 1)

    2010  

    Author's details ed. Sverre E. Kjeldsen
    Series title Blood pressure ; 19, Suppl. 1
    Collection
    Language English
    Size 16 S. : graph. Darst.
    Publisher Informa Healthcare
    Publishing place Stockholm
    Publishing country Sweden
    Document type Book
    HBZ-ID HT016424975
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The role of β-blockers in medical treatment.

    Kjeldsen, Sverre E / Grassi, Guido

    Current medical research and opinion

    2024  Volume 40, Issue sup1, Page(s) 1–2

    MeSH term(s) Humans ; Adrenergic beta-Antagonists/therapeutic use
    Chemical Substances Adrenergic beta-Antagonists
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Editorial
    ZDB-ID 80296-7
    ISSN 1473-4877 ; 0300-7995
    ISSN (online) 1473-4877
    ISSN 0300-7995
    DOI 10.1080/03007995.2024.2324138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Drug therapy supplement

    Kjeldsen, Sverre E.

    (Blood pressure ; 17, Suppl. 2)

    2008  

    Author's details ed. Sverre E. Kjeldsen
    Series title Blood pressure ; 17, Suppl. 2
    Collection
    Language English
    Size 40 S. : graph. Darst.
    Publisher Informa Healthcare
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015821054
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Randomized Clinical Outcome Trials in Hypertension.

    Mancia, Giuseppe / Kjeldsen, Sverre E

    Hypertension (Dallas, Tex. : 1979)

    2023  Volume 81, Issue 1, Page(s) 17–23

    MeSH term(s) Humans ; Hypertension/drug therapy ; Cardiovascular Diseases/drug therapy ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/pharmacology ; Blood Pressure
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.21725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Real-world data show the effect of statins in primary prevention.

    Mariampillai, Julian E / Kjeldsen, Sverre E

    European journal of preventive cardiology

    2023  Volume 30, Issue 17, Page(s) 1881–1882

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Hypertension ; Diabetes Mellitus ; Primary Prevention ; Primary Health Care
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwad231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Drug therapy supplement

    Narkiewicz, Krzysztof / Kjeldsen, Sverre E.

    (Blood pressure ; 20, Suppl. 1)

    2011  

    Author's details ed. Sverre E. Kjeldsen ; Krzysztof Narkiewicz
    Series title Blood pressure ; 20, Suppl. 1
    Collection
    Language English
    Size 25 S. : graph. Darst.
    Publisher Informa Healthcare
    Publishing place Stockholm
    Publishing country Sweden
    Document type Book
    HBZ-ID HT016835504
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: A 30th anniversary and a glimpse of the future.

    Burnier, Michel / Kjeldsen, Sverre E

    Blood pressure

    2022  Volume 31, Issue 1, Page(s) 1–3

    MeSH term(s) Anniversaries and Special Events ; History, 20th Century ; Humans
    Language English
    Publishing date 2022-01-21
    Publishing country England
    Document type Editorial ; Historical Article
    ZDB-ID 1170048-8
    ISSN 1651-1999 ; 1651-2480 ; 0803-7051 ; 0803-8023
    ISSN (online) 1651-1999 ; 1651-2480
    ISSN 0803-7051 ; 0803-8023
    DOI 10.1080/08037051.2021.2021638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Uric acid and left ventricular mass in prediction of cardiovascular risk-New insight from the URRAH study.

    Kjeldsen, Sverre E / Mariampillai, Julian E / Høieggen, Aud

    European journal of internal medicine

    2023  Volume 114, Page(s) 45–46

    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology ; Risk Factors ; Uric Acid ; Hypertension ; Heart Disease Risk Factors ; Hypertrophy, Left Ventricular
    Chemical Substances Uric Acid (268B43MJ25)
    Language English
    Publishing date 2023-05-11
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2023.05.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of antihypertensive treatment in isolated systolic hypertension (ISH) - systematic review and meta-analysis of randomised controlled trials.

    Brunström, Mattias / Carlberg, Bo / Kjeldsen, Sverre E

    Blood pressure

    2023  Volume 32, Issue 1, Page(s) 2226757

    Abstract: Background: Isolated systolic hypertension (ISH) in middle-aged and elderly is associated with high cardiovascular risk, but no randomised controlled trial has assessed the effect of antihypertensive treatment in ISH using today's definition, i.e. ... ...

    Abstract Background: Isolated systolic hypertension (ISH) in middle-aged and elderly is associated with high cardiovascular risk, but no randomised controlled trial has assessed the effect of antihypertensive treatment in ISH using today's definition, i.e. systolic blood pressure (SBP) ≥140 mmHg and diastolic blood pressure (DBP) <90 mmHg.
    Methods: A systematic review and meta-analysis of randomised controlled trials was performed. Studies with ≥1000 patient-years of follow-up, comparing more intensive versus less intensive BP targets, or active drug versus placebo, were included if the mean baseline SBP was ≥140 mmHg and the mean baseline DBP was <90 mmHg. The primary outcome was major adverse cardiovascular events (MACE). Relative risks from each trial were pooled in random-effects meta-analyses, stratified by baseline and attained SBP level.
    Results: Twenty-four trials, including 113,105 participants (mean age 67 years; mean blood pressure 149/83 mmHg) were included in the analysis. Overall, treatment reduced the risk of MACE by 9% (relative risk 0.91, 95% confidence interval 0.88-0.93). Treatment was more effective if baseline SBP was ≥160 mmHg (RR 0.77, 95% CIs 0.70-0.86) compared to 140-159 mmHg (RR 0.92, 95% CIs 0.89-0.95;
    Conclusions: These findings support antihypertensive treatment of isolated systolic hypertension, regardless of baseline SBP, to target SBP <140 mmHg and even <130 mmHg if well tolerated.
    MeSH term(s) Aged ; Middle Aged ; Humans ; Antihypertensive Agents/adverse effects ; Hypertension/drug therapy ; Isolated Systolic Hypertension ; Blood Pressure ; Heart
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 1170048-8
    ISSN 1651-1999 ; 1651-2480 ; 0803-7051 ; 0803-8023
    ISSN (online) 1651-1999 ; 1651-2480
    ISSN 0803-7051 ; 0803-8023
    DOI 10.1080/08037051.2023.2226757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: How to optimize the use of diuretics in patients with heart failure?

    Burnier, Michel / Narkiewicz, Krzysztof / Kjeldsen, Sverre E

    Kardiologia polska

    2023  Volume 81, Issue 10, Page(s) 944–949

    Abstract: Considering the pathophysiology and clinical presentation of heart failure, using diuretics or drugs with diuretic properties is indispensable for adequate management of heart failure patients. However, in clinical practice, fluid expansion is often ... ...

    Abstract Considering the pathophysiology and clinical presentation of heart failure, using diuretics or drugs with diuretic properties is indispensable for adequate management of heart failure patients. However, in clinical practice, fluid expansion is often undiagnosed, and diuretic therapy is not always adequately titrated. Today, several drug classes with diuretic properties are available in addition to classical thiazides, thiazide-like, and loop diuretics. The purpose of this short review is to discuss different ways to optimize diuretic therapy using currently available drugs. Several approaches are considered, including a combination of diuretics to obtain a sequential nephron blockade, use of a drug combining a blocker of the renin-angiotensin system (RAS) and an inhibitor of the metabolism of natriuretic peptides (ARNI), prescription of potassium binders to maintain and up-titrate RAS blockers and mineralocorticoid antagonists, and finally use of inhibitors of renal reabsorption of glucose through the sodium-glucose cotransporter 2 system. Optimal use of these various drug classes should improve the quality of life and reduce the need for hospital admissions and mortality in heart failure patients.
    MeSH term(s) Humans ; Diuretics/therapeutic use ; Quality of Life ; Sodium Chloride Symporter Inhibitors/adverse effects ; Heart Failure ; Glucose/therapeutic use
    Chemical Substances Diuretics ; Sodium Chloride Symporter Inhibitors ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2023-09-18
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/v.kp.97315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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