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  1. Article ; Online: Infizierte, pathologische Humerusfraktur bei Sichelzellanämie – noch ein Einzelfall?

    Ballhause, Tobias Malte / Linke, Philip / Hättich, Annika / Klatte, Till Orla / Frosch, Karl-Heinz / Mader, Konrad

    Unfallchirurgie (Heidelberg, Germany)

    2023  Volume 127, Issue 2, Page(s) 146–150

    Abstract: The vaso-occlusive crises of sickle cell disease are accompanied by bone necrosis, which favors endogenous bacterial colonization and thus osteomyelitis. This poses a major challenge for eradication and fracture management.A 22-year-old patient with ... ...

    Title translation Infectious, pathologic humeral fracture in a patient with sickle cell disease-A rare case?
    Abstract The vaso-occlusive crises of sickle cell disease are accompanied by bone necrosis, which favors endogenous bacterial colonization and thus osteomyelitis. This poses a major challenge for eradication and fracture management.A 22-year-old patient with sickle cell disease sustained a multifragmentary, humeral shaft fracture. During surgical management, pus drained from the fracture site and further diagnostic work-up revealed osteomyelitis with evidence of Klebsiella aerogenes. Septicemia due to Klebsiella aerogenes had been treated 5 months prior to the accident, which occured because of a vaso-occlusive crisis. This is associated with clustered bone necrosis and endogenous germ colonization. Eradication of the germs and fracture care become a challenge. Repeated surgical procedures with segmental transfer can be a successful treatment option.
    MeSH term(s) Humans ; Young Adult ; Adult ; Anemia, Sickle Cell/complications ; Communicable Diseases/complications ; Osteomyelitis/complications ; Osteonecrosis/complications ; Fractures, Spontaneous/complications ; Hemoglobinopathies/complications
    Language German
    Publishing date 2023-06-04
    Publishing country Germany
    Document type Case Reports ; English Abstract ; Journal Article
    ISSN 2731-703X
    ISSN (online) 2731-703X
    DOI 10.1007/s00113-023-01334-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Glenoidfraktur

    Klatte, Till Orla / Mader, Konrad / Frosch, Karl-Heinz

    OP-JOURNAL

    2022  Volume 38, Issue 03, Page(s) 218–226

    Abstract: Glenoidfrakturen stellen im klinischen Alltag eine Rarität da. Neben hochenergetischen Traumata finden sich häufig Luxationsereignisse als Ursache. Nicht nur die Frakturmorphologie, sondern auch das zugrunde liegende Trauma haben einen Einfluss ...

    Abstract Glenoidfrakturen stellen im klinischen Alltag eine Rarität da. Neben hochenergetischen Traumata finden sich häufig Luxationsereignisse als Ursache. Nicht nur die Frakturmorphologie, sondern auch das zugrunde liegende Trauma haben einen Einfluss auf die richtige Entscheidung für die weitere konservative oder operative Behandlung. Insbesondere für größere anteriore Glenoidfrakturen zeigt die aktuelle Literatur gute Ergebnisse für die konservative Behandlung. Hingegen zeigen kleinere Bony-Bankart-Verletzungen eine höhere Instabilitätsrate beim jungen Patienten unter konservativer Therapie. Für die operativen Versorgungstechniken bieten sich zunehmend, neben offenen Verfahren, eine Reihe arthroskopischer Techniken an.
    Keywords Glenoid ; Glenoidfraktur ; Bony-Bankart-Fraktur-Verletzung ; glenoid ; fracture glenoid ; bony bankart lesion
    Language German
    Publishing date 2022-09-27
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2375266-X
    ISSN 1439-2496 ; 0178-1715
    ISSN (online) 1439-2496
    ISSN 0178-1715
    DOI 10.1055/a-1757-7221
    Database Thieme publisher's database

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  3. Book ; Online ; Thesis: Periprothetische Infektionen mit Enterokokken bei Knie-Totalendoprothesen: Resultate nach einzeitig-septischem Wechsel

    Minde, Thore [Verfasser] / Klatte, Till Orla [Akademischer Betreuer]

    2022  

    Author's details Thore Alexis Minde ; Betreuer: Till Orla Klatte
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language Multiple languages
    Publisher Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Article ; Online: Genomics of Invasive Cutibacterium acnes Isolates from Deep-Seated Infections.

    Both, Anna / Huang, Jiabin / Hentschke, Moritz / Tobys, David / Christner, Martin / Klatte, Till Orla / Seifert, Harald / Aepfelbacher, Martin / Rohde, Holger

    Microbiology spectrum

    2023  , Page(s) e0474022

    Abstract: Cutibacterium acnes, formerly known as Propionibacterium acnes, is a commensal of the human pilosebaceous unit but also causes deep-seated infection, especially in the context of orthopedic and neurosurgical foreign materials. Interestingly, little is ... ...

    Abstract Cutibacterium acnes, formerly known as Propionibacterium acnes, is a commensal of the human pilosebaceous unit but also causes deep-seated infection, especially in the context of orthopedic and neurosurgical foreign materials. Interestingly, little is known about the role of specific pathogenicity factors for infection establishment. Here, 86 infection-associated and 103 commensalism-associated isolates of
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04740-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mid-term clinical and sonographic outcomes of minimally invasive acromioclavicular joint reconstruction: mini-open versus arthroscopically assisted.

    Behrens, A / Behrendt, P / Heintzen, M J / Finn, J / Seekamp, A / Mader, K / Lippross, S / Klatte, T O

    Archives of orthopaedic and trauma surgery

    2023  Volume 144, Issue 2, Page(s) 807–814

    Abstract: Introduction: The current literature describes various operative stabilization strategies which achieve good clinical outcomes after acute acromioclavicular joint (ACJ) dislocation. The aim of this study was to compare the mid-term clinical and ... ...

    Abstract Introduction: The current literature describes various operative stabilization strategies which achieve good clinical outcomes after acute acromioclavicular joint (ACJ) dislocation. The aim of this study was to compare the mid-term clinical and sonographic treatment outcomes after minimally invasive mini-open and arthroscopic reconstruction.
    Materials and methods: We conducted a retrospective two-center study of patients with acute ACJ dislocation. Surgical treatment was performed using either a mini-open approach (MIOP) or an arthroscopic technique (AR). The primary outcome parameters of this study were the sonographically measured acromioclavicular (ACD) and coracoclavicular distances (CCD). Secondary outcome parameters included the Constant-Murley score (CS), range of motion (ROM), postoperative pain scale (VAS), return to daily routine, return to sports, complications, as well as operative revisions.
    Results: After a mean follow-up of 29 months, 30 patients were included in this study with an average age of 41.3 ± 14.8 years (MIOP) and 41.2 ± 15.4 years (AR). The sonographic ACD (MIOP 9.11 mm vs. AR 8.93 mm, p = 0.41) and CCD (MIOP 25.08 mm vs. AR 24.36 mm, p = 0.29) distances showed no statistically significant differences. Furthermore, there was no statistically significant difference when compared to the contralateral side (p = 0.42). With both techniques, patients achieved excellent clinical outcome parameters without statistically significant differences in CS (MIOP 95 vs. AR 97, p = 0.11) and VAS (MIOP 1.76 vs. AR 1.14, p = 0.18). The return to daily activity and return to sport rates did not differ. There were neither complications nor revisions in both groups.
    Conclusion: Both minimally invasive techniques for acute ACJ stabilization achieved excellent clinical and sonographic outcomes without one technique being statistically superior to the other.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Acromioclavicular Joint/diagnostic imaging ; Acromioclavicular Joint/surgery ; Joint Dislocations/surgery ; Retrospective Studies ; Arthroscopy/methods ; Shoulder Dislocation/surgery ; Treatment Outcome ; Arthroplasty, Replacement
    Language English
    Publishing date 2023-11-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80407-1
    ISSN 1434-3916 ; 0003-9330 ; 0344-8444
    ISSN (online) 1434-3916
    ISSN 0003-9330 ; 0344-8444
    DOI 10.1007/s00402-023-05110-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Utility of histopathological examination in aseptic revision total hip arthroplasty: a preliminary analysis.

    Rossmann, Markus / Aljawabra, Alaa / Mau, Hans / Citak, Mustafa / Gehrke, Thorsten / Klatte, Till Orla / Abdelaziz, Hussein

    Hip international : the journal of clinical and experimental research on hip pathology and therapy

    2023  Volume 34, Issue 2, Page(s) 201–206

    Abstract: Introduction: The utility of a routine histopathological examination in aseptic revision total hip arthroplasty (THA) has not been well explored. We aim to describe the approach and present the results of histopathological examination, focusing on its ... ...

    Abstract Introduction: The utility of a routine histopathological examination in aseptic revision total hip arthroplasty (THA) has not been well explored. We aim to describe the approach and present the results of histopathological examination, focusing on its clinical usefulness in the setting of aseptic revision THA.
    Method: We retrospectively reviewed 285 performed aseptic revision THA with available histopathological reports between 2015 and 2017 at a single institution. We described histopathological requests by the surgical team. Preoperative diagnoses, intraoperative findings, as well as histopathology and culture results were analysed.
    Results: 13 painful THAs (4.5%) had preoperatively unknown diagnoses. In 10 of them, potential causes of pain were intraoperatively identified. Histopathology confirmed these findings in 8 THAs. 19 THAs (6.7%) revealed unexpected positive cultures (UPC). Histopathology was negative for infection in 18 of them. Among 16 consultants, 3 surgeons requested histopathology in 47% of the cases (130/285), usually to exclude infection (101/285; 35%). Documentation for tissue sample location was lacking in 51% (145/285), and for question asked by the surgeon in 47% (135/285).
    Conclusions: Histopathology is deemed a useful confirmatory tool in the context of ruling out infection in UPCs, and in documenting intraoperative findings in painful THAs with unknown preoperative diagnoses. Importantly, the approach to requesting histopathology should be optimised. Further large-scale studies, including cost analyses, are warranted to explore the usefulness of histopathology in routine utility.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Hip/adverse effects ; Retrospective Studies ; Prosthesis-Related Infections/diagnosis ; Prosthesis-Related Infections/surgery ; Prosthesis-Related Infections/etiology ; Reoperation/methods ; Hip Prosthesis/adverse effects
    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1162513-2
    ISSN 1724-6067 ; 1120-7000
    ISSN (online) 1724-6067
    ISSN 1120-7000
    DOI 10.1177/11207000231197743
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    Zs.A 3810: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article: Posttraumatische Achsfehlstellung mit nachfolgender Ellenbogensteife. Posttraumatic axis malalignment with consecutive posttraumatic elbow stiffness

    Mader, Konrad / Wintges, Kristofer / Klatte, Till Orla

    OUP

    2021  Volume 10, Issue 1, Page(s) 26

    Language German
    Document type Article
    ZDB-ID 2645147-5
    ISSN 2193-5785
    Database Current Contents Medicine

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    Zs.A 6947: Show issues Location:
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  8. Conference proceedings: Performanceanalyse eines Multiplex-PCR Panels und mögliche klinische Anwendungen bei Gelenkinfektionen

    Krivec, Lukas / Berinson, Benjamin Hendrik / Spenke, Laura / Klatte, Till Orla / Rohde, Holger

    2023  , Page(s) AB37–2289

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2023); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2023
    Keywords Medizin, Gesundheit ; Gelenkinfektionen ; septische Arthritis ; mikrobiologischer Erregernachweis ; Multiplex-PCR
    Publishing date 2023-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkou162
    Database German Medical Science

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  9. Article ; Online: [No title information]

    Rolvien, Tim / Stürznickel, Julian / Klatte, Till Orla / Zustin, Jozef

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

    2020  Volume 193, Issue 1, Page(s) 80–82

    Title translation Intraossäres Hibernom der Lendenwirbelsäule.
    MeSH term(s) Female ; Humans ; Lipoma/diagnostic imaging ; Lipoma/pathology ; Lipoma/surgery ; Lumbar Vertebrae ; Magnetic Resonance Imaging/methods ; Middle Aged ; Spinal Neoplasms/diagnostic imaging ; Spinal Neoplasms/pathology ; Spinal Neoplasms/surgery
    Language German
    Publishing date 2020-06-09
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    ISSN (online) 1438-9010
    ISSN 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    DOI 10.1055/a-1172-6628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ue I Zs.12: Show issues Location:
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  10. Article: Influence of Fracture Reduction on the Functional Outcome after Intramedullary Nail Osteosynthesis in Proximal Humerus Fractures.

    Hättich, Annika / Harloff, Tim Jodokus / Sari, Hatice / Schlickewei, Carsten / Cramer, Christopher / Strahl, André / Frosch, Karl-Heinz / Mader, Konrad / Klatte, Till Orla

    Journal of clinical medicine

    2022  Volume 11, Issue 22

    Abstract: Background: Optimal treatment of proximal humeral fractures (PHF) is still controversial. Therefore, we aim to investigate the influence of fracture reduction after intramedullary nailing of a PHF on the clinical outcome. Methods: Patients treated with ... ...

    Abstract Background: Optimal treatment of proximal humeral fractures (PHF) is still controversial. Therefore, we aim to investigate the influence of fracture reduction after intramedullary nailing of a PHF on the clinical outcome. Methods: Patients treated with intramedullary nail for PHF from 2013−2018, (minimum follow-up 12 months) were retrospectively included. Constant Score (CS), DASH and Simple Shoulder Test (SST) were collected. Postoperative radiographs were used to determine head-shaft-alignment (HSA), head-shaft-displacement (HSD), integrity of the medial hinge and the cranialization of the greater tuberosity (CGT). The results of fracture reduction were categorized as either “anatomical”, “acceptable” or as “malreduction”. Malreduction exists when at least one of the following parameters are present: HSA > 150/< 110°, HSD >5 mm, CTM > 5 mm or lack of integrity of the medial hinge. Results: 42 patients (mean age 65.5 ± 14.1 years, 15 male, 27 female) with a mean follow-up time of 43 months were included. The average CS was 60 ± 30, DASH 49.8 ± 24.3 and SST 62.9 ± 26.9. There was an “anatomic” reduction in 9 (21.4%), “acceptable” in 7 (16.6%) and a “malreduction” in 26 (62%) patients. Comparing the combined “anatomical” and “acceptable” reduction group with the “malreduction” group, worse scores were observed in the “malreduction” group (CS 67.2 vs. 55.2, DASH 45.2 vs. 51.9, SST: 69.3 vs. 58.6) without statistical significance (CS: p = 0.095, DASH: p = 0.307, SST: p = 0.400). By means of multiple logistic regression analyses no statistically significant risk factors were identified for lower DASH, CS and SST scores. Conclusions: Anatomical fracture reduction using intramedullary nails has a positive effect on postoperative outcome for the 3 scores recorded, without reaching statistical significance.
    Language English
    Publishing date 2022-11-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11226861
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