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  1. Book ; Audio / Video ; Thesis: Generierung einer ikbb1̱hn-1̱hn/1̱hn--Mauslinie und Charakterisierung der Funktion von I kappa B beta im angeborenen und erworbenen Immunsystem

    Klein, Bettina S.

    2003  

    Author's details vorgelegt von Bettina S. Klein
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 2003
    HBZ-ID HT013698322
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 MO 267 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Thesis: Generierung einer ikbb1̱hn-1̱hn/1̱hn--Mauslinie und Charakterisierung der Funktion von I kappa B beta im angeborenen und erworbenen Immunsystem

    Klein, Bettina S.

    2003  

    Author's details vorgelegt von Bettina S. Klein
    Language German
    Size VI, 104 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Ulm, Univ., Diss., 2003
    HBZ-ID HT013701571
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 D 1215 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Audio / Video ; Online: Interaction of PrPSc with the NF-kappaB signalling pathways

    Bourteele, Soizic / Oesterle, Katja / Klein, Bettina S. / Schmidt, R. / Ludwig. S. / Planz, Oliver

    2005  

    Language English
    Publishing date 2005-03-16
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book ; Audio / Video ; Online: NF-kB2 deficiency in mice leads to impaired immune response after LCMV infections ; NF-κB2 deficiency in mice leads to impaired immune response after LCMV infections

    Klein, Bettina S. / Bourteele, Soizic / Paxian, S. / Schmid, R.M. / Planz, Oliver

    2005  

    Language English
    Publishing date 2005-03-16
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book ; Audio / Video ; Online: NF-kB2 deficiency in mice leads to impaired immune response after LCMV infections ; NF-κB2 deficiency in mice leads to impaired immune response after LCMV infections

    Klein, Bettina S. / Bourteele, Soizic / Paxian, S. / Schmid, R.M. / Planz, Oliver

    2005  

    Keywords Text
    Language English
    Publishing date 2005-03-16
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book ; Audio / Video ; Online: Interaction of PrPSc with the NF-kappaB signalling pathways

    Bourteele, Soizic / Oesterle, Katja / Klein, Bettina S. / Schmidt, R. / Ludwig. S. / Planz, Oliver

    2005  

    Keywords Text
    Language English
    Publishing date 2005-03-16
    Publishing country de
    Document type Book ; Audio / Video ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Immune-mediated destruction of pancreatic islet cells

    Burkart, V. / Ichino, N. / Ohashi, A. / Klein, Bettina S. / Paxian, S. / Schmidt, R.

    Beta cell specific NFkappaB(p65) knock out protects from damage by inflammatory cytokines

    2004  

    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Immune-mediated destruction of pancreatic islet cells

    Burkart, V. / Ichino, N. / Ohashi, A. / Klein, Bettina S. / Paxian, S. / Schmidt, R.

    Beta cell specific NFkappaB(p65) knock out protects from damage by inflammatory cytokines

    2004  

    Keywords Text
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Conditional ablation of Notch signaling in pancreatic development

    Nakhai, Hassan / Siveke, Jens T / Klein, Bettina S. / Mendoza-Torres, Lidia / Mazur, Pawel K. / Algul, Hana / Radtke, Freddy / Strobl, Lothar / Zimber-Strobl, Ursula / Schmid, Roland M.

    2008  

    Abstract: The role of the Notch signaling members Notch1, Notch2 and Rbpj in exocrine pancreatic development is not well defined. We therefore analyzed conditional pancreas-specific Rbpj and combined Notch1/Notch2 knockout mice using Ptf1a(ﰪ(ex1)) mice crossed ... ...

    Abstract The role of the Notch signaling members Notch1, Notch2 and Rbpj in exocrine pancreatic development is not well defined. We therefore analyzed conditional pancreas-specific Rbpj and combined Notch1/Notch2 knockout mice using Ptf1a(ﰪ(ex1)) mice crossed with floxed Rbpj or Notch1/Notch2 mice. Mice were analyzed at different embryonic stages for pancreatic exocrine and endocrine development. The absence of Rbpj in pancreatic progenitor cells impaired exocrine pancreas development up to embryonic day 18.5 and led to premature differentiation of pancreatic progenitors into endocrine cells. In Rbpj-deficient pancreata, amylase-expressing acini and islets formed during late embryonic and postnatal development, suggesting an essential role of Rbpj in early but not late development. Contrary to this severe phenotype, the concomitant inactivation of Notch1 and Notch2 only moderately disturbed the proliferation of pancreatic epithelial cells during early embryonic development, and did not inhibit pancreatic development. Our results show that, in contrast to Rbpj, Notch1 and Notch2 are not essential for pancreatogenesis. These data favor a Notch-independent role of Rbpj in the development of the exocrine pancreas. Furthermore, our findings suggest that in late stages of pancreatic development exocrine cell differentiation and maintenance are independent of Rbpj
    Keywords Text ; ddc:630 ; CELL-DIFFERENTIATION ; CELLS ; COMPLEX ; conditional knockout mice ; development ; DIFFERENTIATION ; ENDOCRINE DEVELOPMENT ; EPITHELIAL-CELLS ; GERMANY ; INACTIVATION ; MICE ; MOUSE ; Notch ; pancreas ; PTF1 ; RBP-J ; Rbpj ; SUPPRESSOR
    Subject code 570
    Language English
    Publishing date 2008-08-15
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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