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  1. Article: Gastrostomy as a Preemptive Measure after Pancreatoduodenectomy against Delayed Gastric Emptying: A Small Case Series and a Review of the Literature.

    Floros, G / Galanis, I / Theodoropoulos, P / Bartziotas, D / Theodoropoulos, C / Metaxa, M / Giannos, G / Tsintavis, P / Stylianidis, G / Klimopoulos, S

    Case reports in surgery

    2021  Volume 2021, Page(s) 6649914

    Abstract: Delayed gastric emptying (DGE) is a common (20-30%) postoperative complication following pancreatoduodenectomy (PD) (Parmar et al., 2013). Various causes and preemptive measures have been suggested to decrease the occurrence of DGE. We added a simple ... ...

    Abstract Delayed gastric emptying (DGE) is a common (20-30%) postoperative complication following pancreatoduodenectomy (PD) (Parmar et al., 2013). Various causes and preemptive measures have been suggested to decrease the occurrence of DGE. We added a simple step in the procedure of 26 consecutive pancreatic head resections, which seems to alleviate DGE and has never been highlighted before.
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2021/6649914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Embedment of the gastroduodenal artery stump into the jejunal serosa: A new technique aiming to prevent post-pancreatectomy hemorrhage.

    Klimopoulos, Serafeim / Charakopoulou, Alexandra / Pantelis, Athanasios / Bouchagier, Konstantinos

    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique

    2019  Volume 26, Issue 4, Page(s) e32–e36

    Abstract: Post-pancreaticoduodenectomy hemorrhage has an estimated incidence of 5% and a mortality rate of 11-38%. Vascular erosion resulting from pancreatic leak and skeletonization of the arterial wall during pancreatic mobilization may be the two possible ... ...

    Abstract Post-pancreaticoduodenectomy hemorrhage has an estimated incidence of 5% and a mortality rate of 11-38%. Vascular erosion resulting from pancreatic leak and skeletonization of the arterial wall during pancreatic mobilization may be the two possible mechanisms responsible for this complication, which most commonly affects the gastroduodenal artery stump. A novel technique of wrapping up the gastroduodenal artery stump into the jejunal serosa to decrease postoperative hemorrhage is presented.
    MeSH term(s) Aged ; Digestive System Surgical Procedures/methods ; Duodenum/blood supply ; Duodenum/surgery ; Female ; Humans ; Jejunum/blood supply ; Jejunum/surgery ; Male ; Middle Aged ; Pancreatectomy/adverse effects ; Pancreatectomy/trends ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/trends ; Postoperative Hemorrhage/diagnosis ; Postoperative Hemorrhage/etiology ; Postoperative Hemorrhage/prevention & control ; Serous Membrane/blood supply ; Serous Membrane/surgery ; Stomach/blood supply ; Stomach/surgery
    Language English
    Publishing date 2019-12-27
    Publishing country Australia
    Document type Journal Article ; Technical Report
    ISSN 2561-8741
    ISSN (online) 2561-8741
    DOI 10.15586/jptcp.v26i4.652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Association between perineural infiltrations and delayed gastric emptying after Whipple procedure for periampullary tumours, and the relationship with other clinicopathological factors and overall survival.

    Bouchagier, Konstantinos / Mulita, Francesk / Verras, Georgios-Ioannis / Nehr, Steffen / Perdikaris, Ioannis / Tasios, Konstantinos / Antzoulas, Andreas / Samaras, Angelos / Klimopoulos, Serafeim / Maroulis, Ioannis

    Przeglad gastroenterologiczny

    2023  Volume 19, Issue 1, Page(s) 89–96

    Abstract: Introduction: Pancreaticoduodenectomy is a major procedure. Delayed gastric emptying (DGE) is a frequent postoperative complication that is attributed to several factors.: Aim: To investigate the probable association between perineural infiltrations ... ...

    Abstract Introduction: Pancreaticoduodenectomy is a major procedure. Delayed gastric emptying (DGE) is a frequent postoperative complication that is attributed to several factors.
    Aim: To investigate the probable association between perineural infiltrations and DGE, and the effects on overall survival.
    Material and methods: A total of 123 patients who underwent pancreaticoduodenectomy were enrolled in the study. Factors like the presence of perineural infiltrations and post-operative DGE along with age, gender, presence of postoperative fistula, and grade of fistula and postoperative haemorrhage were analysed, and survival analyses were conducted.
    Results: The presence of perineural infiltrations is statistically associated with DGE occurrence (
    Conclusions: This is the first study that proves a statistically significant association between the presence of perineural infiltrations and the occurrence of DGE. Moreover, perineural infiltrations are an important independent prognostic factor for overall survival, along with other clinical factors.
    Language English
    Publishing date 2023-07-17
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2596134-2
    ISSN 1897-4317 ; 1895-5770
    ISSN (online) 1897-4317
    ISSN 1895-5770
    DOI 10.5114/pg.2023.129464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Rare Case of Iatrogenic Diaphragm Defect following Laparoscopic Cholecystectomy Presented as Acute Respiratory Distress Syndrome.

    Bouchagier, Konstantinos / Solakis, Evangelos / Klimopoulos, Serafeim / Demesticha, Theano / Filippou, Dimitrios / Skandalakis, Panagiotis

    Case reports in surgery

    2018  Volume 2018, Page(s) 4165842

    Abstract: Laparoscopic cholecystectomy is considered as the gold standard in the treatment of gallbladder disease. Laparoscopy presents significant advantages including decreased hospital stay, better aesthetic results, faster rehabilitation, less pain, reduced ... ...

    Abstract Laparoscopic cholecystectomy is considered as the gold standard in the treatment of gallbladder disease. Laparoscopy presents significant advantages including decreased hospital stay, better aesthetic results, faster rehabilitation, less pain, reduced cost, and increased patient satisfaction. The complications' prevalence is low; however, the overall serious complication rate seems to be higher compared to open cholecystectomy, despite the increasing experience. Diaphragmatic injury following laparoscopic cholecystectomy is an extremely rare complication, and a high index of clinical suspicion is necessary to diagnose this situation that has a variety of clinical presentations and might be life-threatening. We present a unique case of postlaparoscopic cholecystectomy diaphragm defect with late onset. The clinical findings included those of respiratory distress syndrome along with small bowel incarceration and peritonitis.
    Language English
    Publishing date 2018-04-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2018/4165842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Inferior vena cava thrombosis as the initial presentation of IgG4-related retroperitoneal fibrosis: Case report and literature review.

    Simopoulou, Theodora / Klimopoulos, Serafim / Sampaziotis, Dimitrios / Tzortziotis, Apostolos / Bogdanos, Dimitrios / Sakkas, Lazaros I

    Journal of scleroderma and related disorders

    2018  Volume 3, Issue 3, Page(s) NP1–NP6

    Abstract: IgG4-related disease is an immune-mediated deposition of fibro-inflammatory tissue with IgG4-positive plasma cells and dense fibrosis in a single or multiple organs. It often raises concern for malignancy requiring biopsy for diagnosis. Presentation may ... ...

    Abstract IgG4-related disease is an immune-mediated deposition of fibro-inflammatory tissue with IgG4-positive plasma cells and dense fibrosis in a single or multiple organs. It often raises concern for malignancy requiring biopsy for diagnosis. Presentation may vary according to organ involved. IgG4-related retroperitoneal fibrosis accounts for two-thirds of the previously considered idiopathic retroperitoneal fibrosis cases. In IgG4-related retroperitoneal fibrosis, computed tomography scan or magnetic resonance imaging shows periaortic soft tissue that extends from below the kidneys to iliac arteries and entrap ureters causing hydronephrosis and renal failure. We present a rare case of IgG4-related retroperitoneal fibrosis presenting with leg swelling and pain due to inferior vena cava compression and thrombosis, and we review current concepts on disease pathogenesis, diagnosis and treatment.
    Language English
    Publishing date 2018-03-26
    Publishing country England
    Document type Case Reports
    ISSN 2397-1991
    ISSN (online) 2397-1991
    DOI 10.1177/2397198318764793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Delayed presentation of aortoesophageal fistula after endovascular repair.

    Kouritas, Vasileios K / Dedeilias, Panagiotis / Sotiriou, Konstantina / Klimopoulos, Serafim

    Asian cardiovascular & thoracic annals

    2016  Volume 24, Issue 1, Page(s) 51–53

    Abstract: The incidence of aortoesophageal fistula after thoracic endovascular aortic repair has increased following an increase in thoracic endovascular aortic procedures. A 68-year-old man was diagnosed with aortoesophageal fistula 6 years after thoracic ... ...

    Abstract The incidence of aortoesophageal fistula after thoracic endovascular aortic repair has increased following an increase in thoracic endovascular aortic procedures. A 68-year-old man was diagnosed with aortoesophageal fistula 6 years after thoracic endovascular aortic repair of a descending aortic aneurysm. Due to massive hematemesis and instability, he underwent a left thoracotomy, graft repair of the aorta with stent removal, gastrostomy, and proximal esophagostomy. Unfortunately, he died 1 week later due to sepsis. Aortoesophageal fistula may present long after thoracic endovascular aortic repair, and clinicians treating such cases should always be aware of this complication.
    MeSH term(s) Aged ; Aortic Aneurysm, Thoracic/surgery ; Aortography/methods ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation/adverse effects ; Blood Vessel Prosthesis Implantation/instrumentation ; Device Removal ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Esophageal Fistula/diagnosis ; Esophageal Fistula/etiology ; Esophageal Fistula/surgery ; Esophagostomy ; Fatal Outcome ; Gastrostomy ; Hematemesis/etiology ; Humans ; Male ; Reoperation ; Risk Factors ; Sepsis/etiology ; Stents ; Thoracotomy ; Time Factors ; Tomography, X-Ray Computed ; Vascular Fistula/diagnosis ; Vascular Fistula/etiology ; Vascular Fistula/surgery
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1400468-9
    ISSN 1816-5370 ; 0218-4923
    ISSN (online) 1816-5370
    ISSN 0218-4923
    DOI 10.1177/0218492314538035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Peritoneal dialysis without a physical peritoneal dialysis unit.

    Grapsa, E I / Klimopoulos, S / Tseke, P / Papaioannou, N / Tzanatos, H

    Clinical nephrology

    2010  Volume 73, Issue 6, Page(s) 449–453

    Abstract: Unlabelled: Under certain circumstances when patients need peritoneal dialysis (PD) but no physical unit or official staff are available, one has to improvise ways to serve such patients. In this study we describe our experience with such patients ... ...

    Abstract Unlabelled: Under certain circumstances when patients need peritoneal dialysis (PD) but no physical unit or official staff are available, one has to improvise ways to serve such patients. In this study we describe our experience with such patients without a physical peritoneal dialysis unit.
    Patients and methods: Since 1997 we trained 33 patients, mean age 61.7 +/- 12.8 years old. Catheter implantation was done in another hospital on them as out-patients. We used trained nurses made available by the company that supplies the PD solution. After 2004 the whole training was done at patients' home, after having been accepted by the patients.
    Results: Catheter implantation was successful in all 33 patients. Catheter was removed from 2 patients (one and 4 years after implantation) because of relapsing peritonitis in the first and fungal infection in the second. The overall peritonitis rate was 0.18 episodes/patient year or one episode every 63.5 patient months. Actuarial patient survival was 90%, at one year, 83% at second year and 55% at third year. First and second year technique survival were 96%, and 90% respectively.
    Conclusion: Our results, should encourage those who want to provide peritoneal dialysis to their patients even when a physical peritoneal dialysis unit is not available.
    MeSH term(s) Adult ; Aged ; Catheters, Indwelling ; Female ; Hernia/etiology ; Humans ; Male ; Middle Aged ; Patient Education as Topic ; Peritoneal Dialysis, Continuous Ambulatory/adverse effects ; Peritoneal Dialysis, Continuous Ambulatory/methods ; Peritonitis/etiology ; Quality of Life ; Treatment Outcome
    Language English
    Publishing date 2010-05-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185101-9
    ISSN 0301-0430
    ISSN 0301-0430
    DOI 10.5414/cnp73449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Low spigelian hernias: experience of 26 consecutive cases in 24 patients.

    Klimopoulos, S / Kounoudes, C / Validakis, A / Galanis, G

    The European journal of surgery = Acta chirurgica

    2001  Volume 167, Issue 8, Page(s) 631–633

    MeSH term(s) Diagnosis, Differential ; Hernia, Inguinal/diagnosis ; Hernia, Ventral/diagnosis ; Hernia, Ventral/surgery ; Humans
    Language English
    Publishing date 2001-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065288-7
    ISSN 1102-4151 ; 1102-416X ; 0001-5482 ; 1102-1101
    ISSN 1102-4151 ; 1102-416X ; 0001-5482 ; 1102-1101
    DOI 10.1080/110241501753171272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Recent advances in the management of intra-abdominal infections.

    Pissiotis, C A / Klimopoulos, S

    Surgery annual

    1993  Volume 25 Pt 2, Page(s) 59–83

    MeSH term(s) Abscess/therapy ; Bacterial Infections/physiopathology ; Bacterial Infections/therapy ; Humans ; Peritonitis/microbiology ; Peritonitis/physiopathology ; Peritonitis/therapy
    Language English
    Publishing date 1993
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391342-9
    ISSN 0081-9638
    ISSN 0081-9638
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Sclerosing encapsulating peritonitis secondary to CAPD: the effect of fibrotic debridement on further dialysis.

    Klimopoulos, S / Katsoulis, I E / Margellos, V / Nikolopoulou, N

    Journal of the Royal College of Surgeons of Edinburgh

    2002  Volume 47, Issue 2, Page(s) 485–490

    Abstract: Background: Sclerosing peritonitis (SCP) is a complication of continuous ambulatory peritoneal dialysis (CAPD) and is characterized by progressive fibrosis of the peritoneum. Entrapment of the intestine in a fibrous sac resulting in complete intestinal ... ...

    Abstract Background: Sclerosing peritonitis (SCP) is a complication of continuous ambulatory peritoneal dialysis (CAPD) and is characterized by progressive fibrosis of the peritoneum. Entrapment of the intestine in a fibrous sac resulting in complete intestinal obstruction is called sclerosing-encapsulating peritonitis (SEP) and represents the most severe form of the disease. Various reports have been pessimistic regarding the surgical outcome when SEP has caused complete intestinal obstruction. Continuation of CAPD after laparotomy is generally considered not feasible. The aim of this article is to present our experience in the surgical management of SEP and, in particular, in the postoperative continuation of CAPD.
    Material and methods: Seventeen consecutive patients with SCP among 175 patients undergoing CAPD during a period of 14 years in a single Unit were retrospectively reviewed. Two groups of patients were recognized. The SCP group included 9 patients with incomplete intestinal obstruction that were treated with single peritoneal catheter removal and switching to haemodialysis. The SEP group included 8 patients with complete obstruction that necessitated laparotomy for surgical debridement of the fibrotic tissue and release of the intestinal loops.
    Results: Switching to haemodialysis improved the majority of the group of patients. In 2 of the SEP group of patients (early in the series), where enterectomy was inevitable, performance of an intestinal anastomosis resulted in leakage with subsequent fatal outcome. Two of the SEP group of patients were transferred to haemodialysis after the laparotomy. In the remaining 4 SEP patients (50%), exposure of a significant portion of active peritoneal surface was achieved - called "neoperitonization"-and allowed effective continuation of peritoneal dialysis for an average duration of 16 months (range 1-32).
    Conclusions: In patients with SEP, careful release of the intestinal loops avoiding enterectomies and even inadvertent intestinal wounds is mandatory. Continuation of peritoneal dialysis after meticulous debridement and removal of the fibrotic tissue is possible and may be effective. To the best of our knowledge, there have not been previously reported cases of continuations of CAPD after laparotomy for SEP.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; Humans ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Male ; Middle Aged ; Peritoneal Dialysis, Continuous Ambulatory/adverse effects ; Peritonitis/etiology ; Peritonitis/surgery ; Retrospective Studies ; Sclerosis ; Tissue Adhesions/surgery
    Language English
    Publishing date 2002-04
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 390854-9
    ISSN 0035-8835
    ISSN 0035-8835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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