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  1. Article ; Online: In Reply.

    Schmitt, Jochen / Schoffer, Olaf / Klinkhammer-Schalke, Monika

    Deutsches Arzteblatt international

    2024  Volume 121, Issue 6, Page(s) 203–204

    Language English
    Publishing date 2024-04-26
    Publishing country Germany
    Document type Letter
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2023.0265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: [No title information]

    Klinkhammer-Schalke, Monika

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

    2020  Volume 82, Issue 8-09, Page(s) 659–660

    Title translation Wir brauchen strukturierte inhaltliche und formale Vorgehensweisen zur Nutzung versorgungsnaher Daten.
    Language German
    Publishing date 2020-09-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/a-1021-8154
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  3. Article: Qualitätssicherung in der Viszeralonkologie - nur in Zentren möglich?

    Piso, P. / Rückher, J. / Klinkhammer-Schalke, M.

    Forum / Deutsche Krebsgesellschaft

    2022  Volume 37, Issue 1, Page(s) 28

    Language German
    Document type Article
    ZDB-ID 1218650-8
    ISSN 0947-0255
    Database Current Contents Medicine

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  4. Article ; Online: Qualitätsgesicherte Behandlung in zertifizierten Versorgungsnetzwerken von Patientinnen mit Mammakarzinom in der Region Oberfranken: Eine Analyse auf Basis von Bayerischen Krebsregisterdaten.

    Friebel, Sophie / Thater, Andrea / Völkel, Vinzenz / Klinkhammer-Schalke, Monika / Müller-Nordhorn, Jacqueline / Emmert, Martin

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

    2024  

    Abstract: Objectives: Breast cancer is the most common cancer and the most common cancer-related cause of death among women in Germany. The treatment in certified breast cancer centre networks is recommended to ensure high-quality care. The aim of the study was ... ...

    Title translation Quality-assured treatment in certified breast cancer centre networks in Upper Franconia, Germany: An analysis based on data of the Bavarian Cancer Registry.
    Abstract Objectives: Breast cancer is the most common cancer and the most common cancer-related cause of death among women in Germany. The treatment in certified breast cancer centre networks is recommended to ensure high-quality care. The aim of the study was to determine the percentage of breast cancer patients receiving cancer treatment in certified breast cancer centre networks in Upper Franconia, Germany.
    Methods: This study considered the location of treatment and the certification status of providers with regard to initial diagnosis, surgery, chemotherapy, and radiation during breast cancer care. Based on this, we compared patient characteristics receiving cancer care in certified and non-certified cancer centres and their networks. The evaluation was based on a dataset of the Bavarian Cancer Registry (4/2017-3/2022).
    Results: The analysis included 5,545 primary tumors from a total of 5,355 patients (age: 64.5±14.2 years; 99.2% female). The percentage of patients receiving care in certified breast cancer centre networks was 78.8% for initial diagnosis, 82.6% for surgery, 79.5% for chemotherapy, and 99.6% for radiation, respectively. The weighted mean across all treatment sequences was 84.3%. Patients receiving care in certified care networks were significantly younger for three therapy sequences (p+<+0.001). In addition, an above-average proportion of patients with advanced tumor stages were treated in non-certified care networks, especially for diagnosis and surgery (p+<+0.001).
    Conclusions: Regarding the different treatment sequences, we found differences in the proportion of patients who received quality-assured treatment in certified breast cancer centre networks in Upper Franconia. When comparing similar analysis, the results show an average care percentage of patients receiving care in certified care networks. Furthermore, it should be ensured that patients receive comprehensive information about receiving care in certified cancer centre networks.
    Language German
    Publishing date 2024-04-02
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/a-2251-5564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Assessment of the Potential of Concentrating Cancer Care in Hospitals With Certification Through Survival Analysis.

    Bierbaum, Veronika / Schmitt, Jochen / Klinkhammer-Schalke, Monika / Schoffer, Olaf

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))

    2023  Volume 85, Issue S 03, Page(s) S197–S204

    Abstract: Background: Certification programs seek to improve the quality of complex interdisciplinary models of care such as cancer treatment through structuring the process of care in accordance with evidence-based guidelines. In Germany, the German Cancer ... ...

    Title translation Potenzialabschätzung für die Konzentration der Versorgung von Krebspatient:innen in Kliniken mit DKG-Zertifizierung mittels Überlebenszeitanalyse.
    Abstract Background: Certification programs seek to improve the quality of complex interdisciplinary models of care such as cancer treatment through structuring the process of care in accordance with evidence-based guidelines. In Germany, the German Cancer Society (Deutsche Krebsgesellschaft, DKG) provides a certification programme for cancer care that covers more than one thousand centers. In a recent retrospective cohort study, it has been shown on a large, nationwide data set based on data from a statutory health insurance and selected clinical cancer registries, that there is a benefit in survival for cancer patients who have received initial treatment in hospitals certified by the DKG. Here, we deduce two absolute measures from the relative benefit in survival with the aim to quantify this benefit if all patients had been treated in a certified center.
    Methods: The WiZen study analysed survival of adult patients insured by the AOK with a cancer diagnosis between 2009 and 2017 in certified hospitals vs. non-certified hospitals. Besides Kaplan-Meier-estimators, Cox regression with shared frailty was used for 11 types of cancer in total, adjusting for patient-specific information such as demographic characteristics and comorbidities as well as hospital characteristics and temporal trend. Based on this regression, we predict adjusted survival curves that directly address the certification effect. From the adjusted survivals, we calculated years of life lost (YLL) and number needed to treat (NNT), along with a difference in deaths 5 years after diagnosis.
    Results: Based on our estimate for the 537,396 patients that were treated in a non-certified hospital included in the WiZen study, corresponding to 68,7% of the study population, we find a potential of 33,243 YLL per year in Germany based on the size of the German population as of 2017. The potential to avoid death cases 5 years from diagnosis totals 4,729 per year in Germany.
    Conclusion: While Cox regression is an important tool to evaluate the benefit that arises from variables with a potential impact on survival such as certification, its direct results are not well suited to quantify this benefit for decision makers in health care. The estimated years of life lost and the number of deaths that could have been avoided 5 years from diagnosis avoid mis-interpretation of the hazard ratios commonly used in survival analysis and should help to inform key stakeholders in health care without specialist background knowledge in statistics. Our measures, directly adressing the effect of certification, can furthermore be used as a starting point for health-economic calculations. Steering the care of cancer patients primarily to certified hospitals would have a high potential to improve outcomes.
    MeSH term(s) Adult ; Humans ; Retrospective Studies ; Germany/epidemiology ; Certification ; Neoplasms/diagnosis ; Neoplasms/therapy ; Hospitals ; Survival Analysis
    Language German
    Publishing date 2023-09-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/a-2132-6797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Registerbasierte Forschung und klinische Studien : Möglichkeiten, Limitationen, Perspektiven.

    Bierbaum, Thomas / Dreinhöfer, Karsten / Klinkhammer-Schalke, Monika / Schmitt, Jochen

    Orthopadie (Heidelberg, Germany)

    2023  Volume 52, Issue 6, Page(s) 447–454

    Abstract: Register-based research offers a good opportunity to generate knowledge on questions from the clinical practice. Methodologically high-quality register studies can complement clinical studies, especially for questions that cannot be answered with ... ...

    Title translation Register-based research and clinical studies : Possibilities, limitations and perspectives.
    Abstract Register-based research offers a good opportunity to generate knowledge on questions from the clinical practice. Methodologically high-quality register studies can complement clinical studies, especially for questions that cannot be answered with randomized controlled trials (RCT). The ad hoc committee on healthcare data of the German Network for Health Services Research (DNVF) has set methodological guidelines for register-based studies with a manual for methods and the use of healthcare data. The methodological advantages of both approaches can be integrated through RCTs embedded in registers. In Germany there is a diverse register landscape as shown by the register report commissioned by the Federal Ministry of Health, which, however, show a varying degree of internationally recognized quality criteria. The relevance of register-based studies for the clinical practice (e. g. guideline development) is shown in the examples of applications cited in the article. Although a lot has already been done here in Germany with existing register data, sustainable coordination and promotion of the research infrastructure and research culture, especially in international comparison are necessary.
    MeSH term(s) Delivery of Health Care ; Germany ; Health Services Research
    Language German
    Publishing date 2023-05-24
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7153
    ISSN (online) 2731-7153
    DOI 10.1007/s00132-023-04383-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Auswirkungen der COVID-19-Pandemie auf die Inzidenz und Therapie von Krebserkrankungen

    Inwald, E. C. / Klinkhammer-Schalke, M. / Müller-Nordhorn, J.

    Forum / Deutsche Krebsgesellschaft

    2022  Volume 37, Issue 3, Page(s) 198

    Language German
    Document type Article
    ZDB-ID 1218650-8
    ISSN 0947-0255
    Database Current Contents Medicine

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  8. Article ; Conference proceedings: Auswirkungen der COVID-19-Pandemie auf Diagnosestellung und Behandlung des Lungenkarzinoms: eine Analyse des Tumorzentrums Regensburg

    Piler, T / Fluhrer, T / Gerken, M / Klinkhammer-Schalke, M / Ried, M / Hofmann, H-S

    Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie

    2023  Volume 148, Issue S 01

    Event/congress 32. Jahrestagung der Deutschen Gesellschaft für Thoraxchirurgie, Regensburg, 2023-09-20
    Language German
    Publishing date 2023-08-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 200935-3
    ISSN 1438-9592 ; 0044-409X
    ISSN (online) 1438-9592
    ISSN 0044-409X
    DOI 10.1055/s-0043-1771056
    Database Thieme publisher's database

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  9. Article: [No title information]

    Klinkhammer-Schalke, Monika

    Das Gesundheitswesen

    2020  Volume 82, Issue 08/09, Page(s) 659–660

    Abstract: Für die Nutzung vorhandener Versorgungsdaten gibt es immer mehr gute Gründe, wobei v. a. die Nutzung von Registerdaten im Fokus steht. Das zugehörige, klar strukturierte methodische Vorgehen ist bisher noch ... ...

    Abstract Für die Nutzung vorhandener Versorgungsdaten gibt es immer mehr gute Gründe, wobei v. a. die Nutzung von Registerdaten im Fokus steht. Das zugehörige, klar strukturierte methodische Vorgehen ist bisher noch unzureichend zusammengeführt, aufbereitet und transparent dargestellt.
    Language German
    Publishing date 2020-09-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 1101426-x
    ISSN 1439-4421 ; 0941-3790 ; 0949-7013
    ISSN (online) 1439-4421
    ISSN 0941-3790 ; 0949-7013
    DOI 10.1055/a-1021-8154
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  10. Article ; Online: Colorectal cancer survivors' long-term recollections of their illness and therapy up to seven years after enrolment into a randomised controlled clinical trial.

    Völkel, Vinzenz / Steinger, Brunhilde / Koller, Michael / Klinkhammer-Schalke, Monika / Lindberg-Scharf, Patricia

    BMC cancer

    2023  Volume 23, Issue 1, Page(s) 149

    Abstract: Background: As a consequence of effective treatment procedures, the number of long-term survivors of colorectal cancer is ever increasing. Adopting the method of a previous study on breast cancer patients, the goal of the present research was to ... ...

    Abstract Background: As a consequence of effective treatment procedures, the number of long-term survivors of colorectal cancer is ever increasing. Adopting the method of a previous study on breast cancer patients, the goal of the present research was to investigate colorectal cancer patients' recollections of their illness and treatment experiences up to seven years after they have been enrolled in a randomised controlled clinical trial on the direct improvement of quality of life (RCT DIQOL).
    Methods: Colorectal cancer survivors in Bavaria, Germany were mailed a questionnaire on average 78·3 months after the start of their therapy and enrolment into RCT DIQOL. The questionnaire enquired about their worst experience during the colorectal cancer episode, positive aspects of the illness, and any advice they would give to newly diagnosed patients. Patient responses were categorised by two independent raters and cross-checked by a third independent rater. Frequencies of these categories were then quantitatively analysed using descriptive statistics.
    Results: Of 146 remaining survivors initially enrolled in RCT DIQOL, 96 (66%) returned the questionnaire. The majority (33%) of statements regarding the worst experience was referring to "psychological distress", followed by "indigestion and discomfort during defecation" (17%), and "cancer diagnosis" (16%). Among survivors with history of a stoma, the majority (36%) regarded "stoma" as their worst experience. With 45%, "change in life priorities" has been the most frequent positive category before "support by physicians/ nurses" (25%). 43% of the survivors deemed "fighting spirit" as most important advice to overcome the disease.
    Conclusion: Even after many years, colorectal cancer survivors clearly remember experiences from the time of their illness. Echoing the results of the previous breast cancer survivors' study, "psychological distress", "change in life priorities" and "fighting spirit" emerged as prominent concepts. In addition, some aspects like the impact of a stoma are of specific importance for colorectal cancer survivors. These findings can be used to inform programmes to improve patient- and quality of life centred aftercare of tumour patients.
    Clinical trial information: NCT04930016, date of registration 18.06.2021.
    MeSH term(s) Humans ; Female ; Cancer Survivors/psychology ; Quality of Life/psychology ; Colorectal Neoplasms/pathology ; Survivors/psychology ; Breast Neoplasms/therapy ; Breast Neoplasms/psychology
    Language English
    Publishing date 2023-02-13
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-023-10604-z
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