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Book: Psychological aspects of inflammatory bowel disease

Knowles, Simon R. / Mikocka-Walus, Antonina A.

a biopsychosocial approach

2015

Author's details	ed. by Simon R. Knowles and Antonina A. Mikocka-Walus
Keywords	Inflammatory Bowel Diseases / psychology ; Inflammatory Bowel Diseases / complications ; Inflammatory Bowel Diseases / therapy ; Comorbidity ; Anxiety ; Depression
Language	English
Size	XXIV, 226 S.
Publisher	Routledge
Publishing place	London
Publishing country	Great Britain
Document type	Book
Note	Includes bibliographical references
HBZ-ID	HT018395321
ISBN	978-0-415-74125-5 ; 9781315815374 ; 0-415-74125-4 ; 1315815370
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2014 A 3924	available for loan (reading room)	Lesesaal EG

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Article ; Online: Development and validation of a brain fog scale for coeliac disease.

Knowles, Simon R / Apputhurai, Pragalathan / Tye-Din, Jason A

Alimentary pharmacology & therapeutics

2024 Volume 59, Issue 10, Page(s) 1260–1270

Abstract: Background: Brain fog is a subjective cognitive impairment commonly reported in coeliac disease. A standardised tool to define and assess it is an important unmet need.: Aims: To develop a patient-informed tool to assess brain fog in coeliac disease ... ...

Abstract	Background: Brain fog is a subjective cognitive impairment commonly reported in coeliac disease. A standardised tool to define and assess it is an important unmet need. Aims: To develop a patient-informed tool to assess brain fog in coeliac disease to support clinical care, research and drug development. Methods: A pilot online study defined patient descriptors of brain fog. A second study evaluated the factor structure and performance of the scale across two-time points ('Now' and in the 'Past week'). One month later, participants were invited to repeat the study with two online cognitive processing tests, the Stroop task and the trail making test. Results: Among adults with treated coeliac disease, 37 (91.9% F) participated in the pilot study and 510 (88.8% F) in the second study of whom 99 repeated the study 1 month later with 51 completing cognitive testing. The most common brain fog descriptors were 'difficulty focusing', 'difficulty thinking' and 'difficulty finding the right words and communicating'. The 12-item scale reflects 'cognitive impairment' and 'somatic and affective experience' and demonstrates strong psychometric properties. It tracked with patients report of brain fog being present or absent across two-time points. It did not significantly correlate with the cognitive tests. Conclusion: The brain fog assessment and severity scale is the first patient-informed clinical outcomes assessment tool measuring brain fog in coeliac disease. It is brief and validated for two time-based formats. Further research coupling it with biomarker discovery is needed to confirm its validity as a predictor of cognitive performance.
MeSH term(s)	Humans ; Celiac Disease/psychology ; Celiac Disease/complications ; Celiac Disease/physiopathology ; Female ; Male ; Middle Aged ; Pilot Projects ; Adult ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Psychometrics ; Aged ; Neuropsychological Tests ; Reproducibility of Results
Language	English
Publishing date	2024-03-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
ZDB-ID	639012-2
ISSN	1365-2036 ; 0269-2813 ; 0953-0673
ISSN (online)	1365-2036
ISSN	0269-2813 ; 0953-0673
DOI	10.1111/apt.17942
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Article ; Online: A Phenomenological Investigation of Trauma in 18 Adults Living With Inflammatory Bowel Disease.

Glynn, Heidi / Knowles, Simon R

Clinical nursing research

2022 Volume 32, Issue 1, Page(s) 159–170

Abstract: While trauma is recognized as being common in Inflammatory Bowel Disease (IBD) cohorts, limited research has explored how trauma impacts the lived experience of IBD. The aim of this study was to develop an understanding of how trauma impacts the ... ...

Abstract	While trauma is recognized as being common in Inflammatory Bowel Disease (IBD) cohorts, limited research has explored how trauma impacts the lived experience of IBD. The aim of this study was to develop an understanding of how trauma impacts the experience of living with IBD and its subsequent management. An interpretative phenomenological analysis with thematic analysis was conducted. Eighteen adults with IBD participated in this qualitative research study. Key themes identified included: (1) Trauma was associated with the journey of IBD; (2) the impact of IBD and trauma, and (3) coping strategies. Pre-existing non-IBD trauma was prevalent, with several participants reporting links between traumatic events and their IBD diagnosis. Experiences of IBD trauma were described by participants across all stages of their illness journey. The study can assist healthcare professionals to better understand the experience of living with IBD and trauma and the factors that can contribute to traumatic responses.
MeSH term(s)	Adult ; Humans ; Inflammatory Bowel Diseases/complications ; Adaptation, Psychological ; Qualitative Research
Language	English
Publishing date	2022-02-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1146553-0
ISSN	1552-3799 ; 1054-7738
ISSN (online)	1552-3799
ISSN	1054-7738
DOI	10.1177/10547738221075649
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Zs.A 3652: Show issues

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Article ; Online: Editorial: Hospitalization Experiences and Post-traumatic Stress in Inflammatory Bowel Disease: Opportunities for Change.

Glynn, Heidi / Mikocka-Walus, Antonina / Knowles, Simon R

Inflammatory bowel diseases

2022 Volume 29, Issue 5, Page(s) 839–841

MeSH term(s)	Humans ; Stress Disorders, Post-Traumatic ; Inflammatory Bowel Diseases ; Surveys and Questionnaires ; Hospitalization
Language	English
Publishing date	2022-07-26
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	1340971-2
ISSN	1536-4844 ; 1078-0998
ISSN (online)	1536-4844
ISSN	1078-0998
DOI	10.1093/ibd/izac166
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Zs.A 4530: Show issues

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Article ; Online: Medication Adherence Across the Life Span in Inflammatory Bowel Disease: Implications and Recommendations for Nurses and Other Health Providers.

Knowles, Simon R / Alex, George

Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

2020 Volume 43, Issue 1, Page(s) 76–88

Abstract: This article reviews the differences and similarities in medication adherence between adolescent and adult cohorts with inflammatory bowel disease. The review covers the rates of medication adherence, as well as predictors, consequences, and related ... ...

Abstract	This article reviews the differences and similarities in medication adherence between adolescent and adult cohorts with inflammatory bowel disease. The review covers the rates of medication adherence, as well as predictors, consequences, and related interventions. Rates of adherence were more favorable among adolescents (65%-90%) than among adults (55%-70%). Major risk factors for poor adherence in adolescents include low medication knowledge, not establishing good medication habits initially, and peer victimization with low social support. For adults, nonadherence is more frequently unintentional (e.g., forgetting) and occurs more often in the context of a poor-quality patient-physician relationship, low medication knowledge, infrequent/missed appointments, busy lifestyle, and concurrent mental health concerns. Nonadherence to medication is associated with worsening of symptoms and risk of relapse in adults and adolescents. Nurses can play a significant role in influencing adherence to medication in patients with inflammatory bowel disease. In particular, nurses can help to impart knowledge on the importance of medication and identify factors that may help or hinder an individual in terms of adherence. Based on the current review, implications for practice and recommendations for nurses to promote medication adherence across both adolescent and adult cohorts are provided. Limitations of the currently available evidence and suggestions for future research are discussed.
MeSH term(s)	Adolescent ; Adult ; Age Factors ; Humans ; Inflammatory Bowel Diseases/drug therapy ; Inflammatory Bowel Diseases/psychology ; Medication Adherence ; Nurse's Role
Language	English
Publishing date	2020-01-25
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1109536-2
ISSN	1538-9766 ; 1042-895X
ISSN (online)	1538-9766
ISSN	1042-895X
DOI	10.1097/SGA.0000000000000467
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Zs.A 3422: Show issues

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Article ; Online: Development and Validation of the Gastrointestinal Unhelpful Thinking Scale (GUTs): A Brief Self-Report Measure for Clinical and Research Settings.

Knowles, Simon R / Apputhurai, Pragalathan / Burgell, Rebecca E / Keefer, Laurie

Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

2022 Volume 45, Issue 1, Page(s) E1–E12

Abstract: This article describes the development and validation of the Gastrointestinal Unhelpful Thinking scale. The purpose of the research was to develop the Gastrointestinal Unhelpful Thinking scale to assess in tandem the primary cognitive-affective drivers ... ...

Abstract	This article describes the development and validation of the Gastrointestinal Unhelpful Thinking scale. The purpose of the research was to develop the Gastrointestinal Unhelpful Thinking scale to assess in tandem the primary cognitive-affective drivers of brain-gut dysregulation, gastrointestinal-specific visceral anxiety, and pain catastrophizing. The research involved 3 phases which included undergraduate and community samples. In the first phase, an exploratory factor analysis revealed a 15-item 2-factor (visceral sensitivity and pain catastrophizing) scale (N= 323), which then was confirmed in the second phase: N = 399, χ2(26) = 2.08, p = .001, Tucker-Lewis Index = 0.94, comparative fit index = 0.96, standardized root mean square residual = 0.05, and root mean square error of approximation = 0.07. Demonstrating convergent validity, Gastrointestinal Unhelpful Thinking scale total and subscales were strongly correlated with the modified Manitoba Index, Irritable Bowel Syndrome Symptom Severity Scale scores, Visceral Sensitivity Index, and the Pain Catastrophizing Scale. A third phase (N = 16) established test-retest reliability for the Gastrointestinal Unhelpful Thinking scale (total and subscales). The test-retest reliability correlation coefficient for the Gastrointestinal Unhelpful Thinking scale total score was .93 (p < .001) and for the subscales was .86 (p < .001) and .94 (p < .001), respectively. The Gastrointestinal Unhelpful Thinking scale is a brief psychometrically valid measure of visceral anxiety and pain catastrophizing that can be useful for both clinicians and researchers who wish to measure these thinking patterns and relate them to changes in gastrointestinal and psychological symptoms.
MeSH term(s)	Factor Analysis, Statistical ; Humans ; Psychometrics ; Reproducibility of Results ; Self Report ; Surveys and Questionnaires
Language	English
Publishing date	2022-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1109536-2
ISSN	1538-9766 ; 1042-895X
ISSN (online)	1538-9766
ISSN	1042-895X
DOI	10.1097/SGA.0000000000000644
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Article ; Online: Exploring the Impact of Trauma and Psychosocial Processes on the Quality of Life in Individuals Living with Inflammatory Bowel Disease.

Glynn, Heidi / Apputhurai, Pragalathan / Moore, Gregory T / Knowles, Simon R

Journal of gastrointestinal and liver diseases : JGLD

2022 Volume 31, Issue 3, Page(s) 301–308

Abstract: Background and aims: Post traumatic stress disorder (PTSD) is common in individuals with inflammatory bowel diseases (IBD). Living with a medical condition has been linked to the development of PTSD and to adversely impact patient outcomes. The aim of ... ...

Abstract	Background and aims: Post traumatic stress disorder (PTSD) is common in individuals with inflammatory bowel diseases (IBD). Living with a medical condition has been linked to the development of PTSD and to adversely impact patient outcomes. The aim of this study is to extend the common sense model (CSM) and evaluate trauma as an additional psychosocial process in the relationship between IBD symptoms and quality of life (QoL). Method: A cross-sectional online study exploring trauma and IBD was performed. Results: 68 (32.2%) of the sample met the criteria for PTSD. Of this trauma group, 37 (54.4%) reported IBD related trauma, 21 (30.9%) reported non-IBD related trauma and 10 (14.7%) did not identify the trauma type. A structural equation model (SEM) based upon the CSM was found to have an excellent fit (χ2 (3)=1.10, p=0.35, RMSEA=0.02, SRMR=0.02, CFI=1.00, GFI=0.99). Results showed that trauma symptoms partially mediated the relationship between illness perceptions and QoL and fully mediated the relationship between maladaptive coping and QoL. Conclusion: This study extended the CSM and found that trauma symptoms functioned as a mediator between IBD activity and QoL. These results highlight the need for a holistic approach including psychological assessment and intervention in IBD.
MeSH term(s)	Chronic Disease ; Cross-Sectional Studies ; Humans ; Inflammatory Bowel Diseases/psychology ; Perception ; Quality of Life/psychology ; Surveys and Questionnaires
Language	English
Publishing date	2022-09-15
Publishing country	Romania
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2427021-0
ISSN	1842-1121 ; 1841-8724
ISSN (online)	1842-1121
ISSN	1841-8724
DOI	10.15403/jgld-4302
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Editorial: brain-gut research needs objective measures of disease activity and mental disorders.

Mikocka-Walus, Antonina / Knowles, Simon R

Alimentary pharmacology & therapeutics

2021 Volume 54, Issue 10, Page(s) 1359–1360

MeSH term(s)	Brain ; Humans ; Mental Disorders/diagnosis
Language	English
Publishing date	2021-11-12
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	639012-2
ISSN	1365-2036 ; 0269-2813 ; 0953-0673
ISSN (online)	1365-2036
ISSN	0269-2813 ; 0953-0673
DOI	10.1111/apt.16639
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Article ; Online: Understanding disease-specific and non-specific factors predicting disordered eating in adults with coeliac disease.

Fraser, Carley N / Möller, Stephan P / Knowles, Simon R

Appetite

2021 Volume 168, Page(s) 105744

Abstract: An adverse relationship between coeliac disease and the development of disordered eating patterns is well established. The aim of this study was to replicate and extend Satherley et al.'s (2016) study exploring coeliac-specific and non-specific factors ... ...

Abstract	An adverse relationship between coeliac disease and the development of disordered eating patterns is well established. The aim of this study was to replicate and extend Satherley et al.'s (2016) study exploring coeliac-specific and non-specific factors predicting disordered eating. An online survey was completed by 187 adults with coeliac disease (90.4% female; Mean age = 48.92; Mean years living with coeliac disease = 11.86). Results indicated that greater disordered eating correlated with being female, poorer dietary adherence, greater gastrointestinal and psychological symptoms, and more coeliac-related food concerns. Hierarchical regression analyses found that psychological distress remained the only predictor of disordered eating when both coeliac-specific and non-specific factors were considered. Age, body mass index, psychological distress, years with coeliac disease and dietary nonadherence were found to significantly predict binge eating severity. The findings suggest that psychological distress is a risk factor for disordered eating in coeliac disease and that binge eating behaviours may be a particularly relevant factor for dietary nonadherence in those living with coeliac disease.
MeSH term(s)	Adult ; Bulimia ; Celiac Disease/complications ; Feeding and Eating Disorders/complications ; Female ; Humans ; Male ; Middle Aged ; Psychological Distress ; Surveys and Questionnaires
Language	English
Publishing date	2021-10-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2021.105744
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Article ; Online: Editorial: type D personality and its relationship with depression and disease activity in inflammatory bowel disease.

Knowles, Simon R / Mikocka-Walus, Antonina

Alimentary pharmacology & therapeutics

2021 Volume 54, Issue 1, Page(s) 80–81

MeSH term(s)	Anxiety ; Colitis ; Depression ; Humans ; Inflammatory Bowel Diseases ; Type D Personality
Language	English
Publishing date	2021-06-09
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	639012-2
ISSN	1365-2036 ; 0269-2813 ; 0953-0673
ISSN (online)	1365-2036
ISSN	0269-2813 ; 0953-0673
DOI	10.1111/apt.16379
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