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  1. Article ; Online: Knochensequester beim Alpaka in Deutschland.

    Kobera, Ralph / Wagner, Henrik

    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere

    2018  Volume 46, Issue 2, Page(s) 109–114

    Abstract: Bone sequestration is relatively unknown in New-world camelids in Germany and is frequently wrongly addressed as neoplasia by veterinary practitioners. This clinical case report describes diagnosis and treatment for bone sequestration in alpacas based on ...

    Title translation Bone sequestration in alpacas in Germany - A practice report with 12 cases.
    Abstract Bone sequestration is relatively unknown in New-world camelids in Germany and is frequently wrongly addressed as neoplasia by veterinary practitioners. This clinical case report describes diagnosis and treatment for bone sequestration in alpacas based on 12 cases. The main symptom of the presented alpacas was moderate to severe lameness in one limb. Some of the patients had been treated with nonsteroidal anti-inflammatory drugs by the referring veterinarian. In eight alpacas, palpation of the swelling in the affected leg was painful and in five animals, exudation was observed. Radiographic imaging led to a correct diagnosis in all of the cases. Following surgical removal of the bone sequestrum, the lameness was already noticeably improved by the third postoperative day. In all patients, healing was achieved without any complications. These results show that bone sequestration in alpacas can be treated successfully by timely surgery. This is the first case report on this topic in alpacas in Germany.
    MeSH term(s) Animals ; Bone Diseases/diagnostic imaging ; Bone Diseases/therapy ; Bone Diseases/veterinary ; Camelids, New World ; Lameness, Animal/diagnostic imaging ; Lameness, Animal/therapy
    Language German
    Publishing date 2018-05-04
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ISSN 2567-5834
    ISSN (online) 2567-5834
    DOI 10.15653/TPG-170580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Knochensequester beim Alpaka in Deutschland

    Kobera, Ralph / Wagner, Henrik

    Tierärztliche Praxis G: Großtiere/Nutztiere

    2018  Volume 46, Issue 02, Page(s) 109–114

    Abstract: Das Auftreten eines Knochensequesters bei Neuweltkameliden ist in Deutschland relativ unbekannt und wird von praktizierenden Tierärzten oft fälschlicherweise als Tumorerkrankung angesprochen. Der Erfahrungsbericht aus der Praxis beschreibt anhand von 12 ... ...

    Abstract Das Auftreten eines Knochensequesters bei Neuweltkameliden ist in Deutschland relativ unbekannt und wird von praktizierenden Tierärzten oft fälschlicherweise als Tumorerkrankung angesprochen. Der Erfahrungsbericht aus der Praxis beschreibt anhand von 12 Fällen eines Knochensequesters beim Alpaka das diagnostische und therapeutische Vorgehen. Die vorgestellten Alpakas zeigten als Leitsymptom eine mittelbis hochgradige Lahmheit einer Gliedmaße. Einige Tiere waren vom Haustierarzt mit einem nichtsteroidalen Antiphlogistikum vorbehandelt worden. Bei acht Alpakas bestand an der betroffenen Gliedmaße weiterhin eine druckdolente Schwellung, aus der bei fünf Patienten Exsudat austrat. Die Röntgenuntersuchung führte bei allen Alpakas zur korrekten Diagnose. Nach chirurgischer Entfernung des Sequesters war die Lahmheit bereits am 3. Tag post operationem sichtbar besser. Bei allen Tieren kam es zu einer komplikationslosen Heilung. Die Resultate zeigen, dass Knochensequester beim Alpaka durch rechtzeitige Behandlung erfolgreich therapiert werden können. Dies ist der erste Praxisbericht zu dieser Thematik beim Alpaka in Deutschland.
    Keywords Neuweltkameliden ; Diagnostik ; Behandlung ; Lahmheit ; New world camelids ; diagnostics ; treatment ; lameness
    Language German
    Publishing date 2018-04-01
    Publisher Schattauer GmbH
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2178387-1
    ISSN 2567-5834 ; 1434-1220
    ISSN (online) 2567-5834
    ISSN 1434-1220
    DOI 10.15653/TPG-170580
    Database Thieme publisher's database

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  3. Article: New World camelids are sentinels for the presence of Borna disease virus

    Malbon, Alexandra J. / Dürrwald, Ralf / Kolodziejek, Jolanta / Nowotny, Norbert / Kobera, Ralph / Pöhle, Dietrich / Muluneh, Aemero / Dervas, Eva / Cebra, Christopher / Steffen, Frank / Paternoster, Giulia / Gerspach, Christian / Hilbe, Monika

    Transboundary and emerging diseases. 2022 Mar., v. 69, no. 2

    2022  

    Abstract: Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) ... ...

    Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV‐1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white‐toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission. Recently, BoDV‐1 attracted attention as a cause of fatal encephalitis in humans. Here, we report investigations on BoDV‐1‐infected llamas from a farm in a BD endemic area of Switzerland, and alpacas from holdings in a region of Germany where BD was last seen in the 1960s but not thereafter. All New World camelids showed apathy and abnormal behaviour, necessitating euthanasia. Histologically, severe non‐suppurative meningoencephalitis with neuronal Joest‐Degen inclusion bodies was observed. BoDV‐1 was confirmed by immunohistology, RT‐qPCR, and sequencing in selected animals. Analysis of the llama herd over 20 years showed that losses due to clinically suspected BD increased within the last decade. BoDV‐1 whole‐genome sequences from one Swiss llama and one German alpaca and—for comparison—from one Swiss horse and one German shrew were established. They represent the first published whole‐genome sequences of BoDV‐1 clusters 1B and 3, respectively. Our analysis suggests that New World camelids may have a role as a sentinel species for BoDV‐1 infection, even when symptomatic cases are lacking in other animal species.
    Keywords Borna disease ; Borna disease virus ; Camelidae ; Crocidura ; abnormal behavior ; alpacas ; euthanasia ; farms ; herds ; horses ; indicator species ; llamas ; meningoencephalitis ; neurons ; sheep ; shrews ; virus transmission ; Germany ; Switzerland
    Language English
    Dates of publication 2022-03
    Size p. 451-464.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.14003
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: New World camelids are sentinels for the presence of Borna disease virus.

    Malbon, Alexandra J / Dürrwald, Ralf / Kolodziejek, Jolanta / Nowotny, Norbert / Kobera, Ralph / Pöhle, Dietrich / Muluneh, Aemero / Dervas, Eva / Cebra, Christopher / Steffen, Frank / Paternoster, Giulia / Gerspach, Christian / Hilbe, Monika

    Transboundary and emerging diseases

    2021  Volume 69, Issue 2, Page(s) 451–464

    Abstract: Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white-toothed shrew (Crocidura leucodon) ... ...

    Abstract Borna disease (BD), a frequently fatal neurologic disorder caused by Borna disease virus 1 (BoDV-1), has been observed for decades in horses, sheep, and other mammals in certain regions of Europe. The bicoloured white-toothed shrew (Crocidura leucodon) was identified as a persistently infected species involved in virus transmission. Recently, BoDV-1 attracted attention as a cause of fatal encephalitis in humans. Here, we report investigations on BoDV-1-infected llamas from a farm in a BD endemic area of Switzerland, and alpacas from holdings in a region of Germany where BD was last seen in the 1960s but not thereafter. All New World camelids showed apathy and abnormal behaviour, necessitating euthanasia. Histologically, severe non-suppurative meningoencephalitis with neuronal Joest-Degen inclusion bodies was observed. BoDV-1 was confirmed by immunohistology, RT-qPCR, and sequencing in selected animals. Analysis of the llama herd over 20 years showed that losses due to clinically suspected BD increased within the last decade. BoDV-1 whole-genome sequences from one Swiss llama and one German alpaca and-for comparison-from one Swiss horse and one German shrew were established. They represent the first published whole-genome sequences of BoDV-1 clusters 1B and 3, respectively. Our analysis suggests that New World camelids may have a role as a sentinel species for BoDV-1 infection, even when symptomatic cases are lacking in other animal species.
    MeSH term(s) Animals ; Borna Disease/epidemiology ; Borna Disease/pathology ; Borna disease virus/genetics ; Camelids, New World ; Encephalitis/veterinary
    Language English
    Publishing date 2021-02-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.14003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  5. Book ; Thesis: Vergleichende Prüfung der klinischen Wirksamkeit von Cefquinom und Enrofloxacin bei der Behandlung des Mastitis-Metritis-Agalaktie-Komplexes der Sau

    Kobera, Ralph

    2000  

    Author's details von Ralph Kobera
    Language German
    Size 110 S, graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Leipzig, 2000
    Database Special collection on veterinary medicine and general parasitology

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