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  1. Article ; Online: Responsiveness to pembrolizumab in severe early-onset natalizumab associated PML-IRIS in patient with relapsing-remitting multiple sclerosis.

    Ercan, Merve Bahar / Kocer, Belgin / Altiparmak, Taylan / Arslan, Ilker

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2024  , Page(s) 13524585241231655

    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Letter
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/13524585241231655
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    Zs.A 4428: Show issues Location:
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  2. Article ; Online: Illustration of the Long-Term Efficacy of Deep Brain Stimulation of the Thalamic Ventral Intermediate Nucleus in a Patient with Holmes Tremor Secondary to Stroke.

    Onder, Halil / Kocer, Bilge / Turan, Aynur / Comoglu, Selcuk

    Movement disorders clinical practice

    2023  Volume 10, Issue 7, Page(s) 1143–1145

    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Case Reports
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.13741
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  3. Article ; Online: Reply to the editor: should multifocality be an indication for prophylactic neck dissection for papillary thyroid cancer?

    Ozdemir, Kayhan / Kocer, Belma / Bayhan, Zulfu

    Updates in surgery

    2023  Volume 75, Issue 8, Page(s) 2421

    Language English
    Publishing date 2023-09-08
    Publishing country Italy
    Document type Letter
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-023-01645-x
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    Zs.B 101: Show issues Location:
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  4. Article ; Online: CNS demyelination associated with nilotinib.

    Erturul, Ezgi / Kocer, Belgin / Gokce, Saliha / Ucar, Murat

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 44, Issue 9, Page(s) 3335–3339

    MeSH term(s) Humans ; Demyelinating Diseases/chemically induced ; Demyelinating Diseases/diagnostic imaging ; Pyrimidines/adverse effects
    Chemical Substances nilotinib (F41401512X) ; Pyrimidines
    Language English
    Publishing date 2023-05-03
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-06827-4
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  5. Book ; Thesis: Epidemiologische Untersuchungen am Kollektiv der Melanompatienten der Dermatologischen Klinik der Westfälischen Wilhelms-Universität Münster

    Koçer, Burak

    2000  

    Author's details vorgelegt von Burak Koçer
    Language German
    Size 90 Bl. : graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Münster (Westfalen), Univ., Diss., 2000
    HBZ-ID HT013275731
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2002 MB 1285 order for loan Magazin

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  6. Article: Critical care for lung cancer patients: surgical treatment during COVID-19 pandemic.

    Gokce, A / Hatipoglu, M / Akboga, S A / Sezen, A I / Akkas, Y / Kocer, B

    Bratislavske lekarske listy

    2022  Volume 123, Issue 2, Page(s) 125–128

    Abstract: Background: During the COVID-19 pandemic, some factors have led to changes in the management of patients with lung cancer. In our study, we aimed to present our surgical treatment approach to patients with NSCLC during the COVID-19 pandemic.: Methods!# ...

    Abstract Background: During the COVID-19 pandemic, some factors have led to changes in the management of patients with lung cancer. In our study, we aimed to present our surgical treatment approach to patients with NSCLC during the COVID-19 pandemic.
    Methods: Patients who underwent surgery for NSCLC in our thoracic surgery clinic between March 2020 and March 2021 were evaluated retrospectively. The patients operated on were retrospectively evaluated in terms of sex, age, tumor staging, lung resection type, histopathological type, COVID-19 status, length of stay, complications, and mortality.
    Results: Thirty-five patients, 27 men and 8 women, underwent surgery for lung cancer. The 2 most common types of surgery were lobectomy (in 32 patients) and pneumonectomy (in 3 patients). According to cancer staging based on 8th TNM, 14 patients were stage 2B, 12 patients were stage 2A, and 9 patients were stage 3A. The morbidity rate was 14 %. No postoperative mortality was observed. Nine patients had a history of COVID- 19 before surgery. No significant difference was found in terms of complications in patients with a preoperative history of COVID-19. In the postoperative period, COVID-19 was observed in no patient in our clinic.
    Conclusion: We think that surgical treatments should not be postponed for diseases such as lung cancer, where the mortality rate is high and early diagnosis and treatment are very important. There will be no delay or inadequacy in the treatment of patients if the rules determined during the COVID-19 pandemic and other types of pandemic possibly occurring in the future are followed (Tab. 1, Ref. 23).
    MeSH term(s) COVID-19 ; Critical Care ; Female ; Humans ; Lung Neoplasms/epidemiology ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Male ; Neoplasm Staging ; Pandemics ; Pneumonectomy ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2022-01-19
    Publishing country Slovakia
    Document type Journal Article
    ZDB-ID 127421-1
    ISSN 0006-9248
    ISSN 0006-9248
    DOI 10.4149/BLL_2022_019
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    Zs.B 355: Show issues Location:
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  7. Article ; Online: The effect of deep brain stimulation on lower extremity dexterity in people with Parkinson's disease.

    Gülşen, Çağrı / Koçer, Bilge / Söke, Fatih / Özcan Gülşen, Elvan / Yılmaz, Öznur / Çomoğlu, Selim Selçuk

    Disability and rehabilitation

    2024  , Page(s) 1–6

    Abstract: Purpose: To examine the effect of deep brain stimulation (DBS) on lower extremity dexterity in people with Parkinson's disease (PwPD) and to investigate the relationship between this effect and the effect of DBS on measures of different walking ... ...

    Abstract Purpose: To examine the effect of deep brain stimulation (DBS) on lower extremity dexterity in people with Parkinson's disease (PwPD) and to investigate the relationship between this effect and the effect of DBS on measures of different walking characteristics, and other features of Parkinson's disease.
    Materials and methods: Thirty-six PwPD were included. Assessment was performed twice with DBS "on" and DBS "off" state.
    Results: The LEDT scores of both extremities, the Unified Parkinson Disease Rating Scale-motor section (UPDRS-III), the 10-Meter Walk Test (TMWT), the Timed Up and Go Test (TUG), the Figure-of-Eight Walk Test (FEWT), and the Three-Meter Backward Walk Test (TMBWT) scores were significantly better in "on" DBS condition than "off" DBS condition. The effect of DBS on lower extremity dexterity is related to age and levodopa equivalent daily dosage (LEDD). The effect of DBS on lower extremity dexterity and the effect of DBS on the bradykinesia, TUG, the FEWT, and the TMBWT were also related.
    Conclusions: DBS has a positive effect on lower extremity dexterity. Clinical characteristics such as age and LEDD and the effect of DBS on bradykinesia, walking with turning, curved walking, and backward walking is related with the effect of DBS on lower extremity dexterity.
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104775-6
    ISSN 1464-5165 ; 0963-8288
    ISSN (online) 1464-5165
    ISSN 0963-8288
    DOI 10.1080/09638288.2024.2317997
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    Zs.A 1569: Show issues Location:
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  8. Article: Bilateral Posteroventral GPi-DBS in a Patient with Tourette's Syndrome - A Rapidly Effective But Under-utilized Therapy.

    Onder, Halil / Kertmen, Hayri / Kocer, Bilge / Ercan, Elif / Comoglu, Selcuk

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 4, Page(s) 574–577

    Language English
    Publishing date 2023-08-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_489_23
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  9. Article ; Online: The effect of subthalamic nucleus deep brain stimulation and dopaminergic treatment on dual-task manual dexterity in Parkinson's disease.

    Gülşen, Çağrı / Koçer, Bilge / Çomoğlu, Selim Selçuk / Gündüz, Arzu Güçlü

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 44, Issue 5, Page(s) 1633–1641

    Abstract: Background and purpose: Dual-task manual dexterity is required to perform activities of daily living and is affected by cognitive functions. This study aimed to investigate the effects of two main treatment options, subthalamic nucleus deep brain ... ...

    Abstract Background and purpose: Dual-task manual dexterity is required to perform activities of daily living and is affected by cognitive functions. This study aimed to investigate the effects of two main treatment options, subthalamic nucleus deep brain stimulation (STN-DBS) and dopaminergic treatment (DT), on dual-task manual dexterity and cognitive functions of people with Parkinson's disease (PwPD).
    Methods: Twenty-one PwPD were assessed in four different conditions as medication "on-off" and STN-DBS "on-off" in random order. Motor symptoms were measured with the Movement Disorder Society-Unified Parkinson Disease Rating Scale, motor section (MDS-UPDRS-III). Single and dual-task manual dexterity was assessed with the Nine-Hole Peg Test (NHPT) and cognitive functions were assessed with the Stroop Test (ST) and the Trail Making Test (TMT).
    Results: Both DT and STN-DBS enhanced MDS-UPDRS-III, and the combination of DT and STN-DBS provided further improvement. Only STN-DBS enhanced dominant hand single-task NHPT scores. Non-dominant single-task NHPT scores and dual-task NHPT scores improved with both treatments alone; however, STN-DBS resulted in more improvement than DT. Dual-task interference, ST, and TMT scores improved with both treatments alone; however, combining DT and STN-DBS did not provide more improvement.
    Conclusion: DT, STN-DBS, and combining both treatments have different effects on motor symptoms, single and dual-task manual dexterity, dual-task interference, and cognitive functions. These results indicate that DT and STN-DBS may affect motor and cognitive functions via different mechanisms. Effects of DT and STN-DBS on manual dexterity may depend on the degree of cognitive involvement in manual dexterity tasks.
    MeSH term(s) Humans ; Subthalamic Nucleus ; Parkinson Disease/complications ; Parkinson Disease/therapy ; Parkinson Disease/psychology ; Deep Brain Stimulation/methods ; Activities of Daily Living ; Treatment Outcome ; Dopamine
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2023-01-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-06589-5
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  10. Article ; Online: Idiopathic normal pressure hydrocephalus-like MRI features in patients with progressive supranuclear palsy: a comparative case-control study.

    Onder, Halil / Kocer, Bilge / Comoglu, Selcuk

    Neurological research

    2022  Volume 44, Issue 9, Page(s) 807–813

    Abstract: Background: The occurrence of neurodegenerative disease in patients with normal pressure hydrocephalus (NPH) is emphasized in recent reports. Based on this common co-occurrence, some of the hydrocephalic disorders appearing in late adulthood have been ... ...

    Abstract Background: The occurrence of neurodegenerative disease in patients with normal pressure hydrocephalus (NPH) is emphasized in recent reports. Based on this common co-occurrence, some of the hydrocephalic disorders appearing in late adulthood have been hypothesized to result from initially unapparent parenchymal abnormalities of neurodegenerative origin. Among these diseases, progressive supranuclear palsy (PSP) has been specifically remarked on. We aimed to comparatively investigate the neuroimaging clues of iNPH in our PSP subjects.
    Methods: Eighteen patients with a clinical diagnosis of PSP, 44 with Parkinson's disease (PD), and 44 healthy control (HC) individuals were enrolled. The disproportionately enlarged subarachnoid space hydrocephalus (DESH) score, the Evans' index (EI), and the callosal angle (CA) were measured on the conventional magnetic resonance imaging (MRI). The comparative analyses were performed using IBM SPSS Statistics 26.
    Results: We found that dilated Sylvian fissures score (p = 0.016) and focal sulcal dilatation score (p = 0.037) were higher in the PSP group in comparison to HC whereas the CA score was higher in PSP subjects in comparison to both PD patients and HC (p = 0.000). Remarkably, the DESH score was also found to be higher in the PSP group in comparison to the age-matched HC group (p = 0.024).
    Conclusions: We found that the NPH-like MRI features were more common in PSP subjects in comparison to PD subjects and age-matched HC. These results may provide critical contributions to the literature regarding the overlap between PSP and NPH.
    MeSH term(s) Adult ; Case-Control Studies ; Humans ; Hydrocephalus, Normal Pressure/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Neurodegenerative Diseases ; Parkinson Disease/diagnostic imaging ; Parkinson Disease/pathology ; Supranuclear Palsy, Progressive/diagnostic imaging
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 424428-x
    ISSN 1743-1328 ; 0161-6412
    ISSN (online) 1743-1328
    ISSN 0161-6412
    DOI 10.1080/01616412.2022.2052622
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