Article ; Online: Evaluation of Remineralizing Capacity of P11-4, CPP-ACP, Silver Diamine Fluoride, and NovaMin: An
The journal of contemporary dental practice
2021 Volume 22, Issue 4, Page(s) 357–360
Abstract: Aim and objective: To determine and compare remineralizing efficacy of NovaMin, CPP-ACP, silver diamine fluoride (SDF), and P11-4.: Materials and methods: Sixty permanent premolars were divided into four groups with 15 samples in each group; group I: ...
Abstract | Aim and objective: To determine and compare remineralizing efficacy of NovaMin, CPP-ACP, silver diamine fluoride (SDF), and P11-4. Materials and methods: Sixty permanent premolars were divided into four groups with 15 samples in each group; group I: self-assembling peptide (P11-4), group II: SDF, group III: Casein phosphopeptide-stabilized amorphous calcium phosphate (CPP-ACP), and group IV: NovaMin. Mineral content was assessed using a scanning electron microscope at 7, 14, and 21 days after remineralization with each agent. Results: The mean remineralization in group I at 7 days was 1.73 ± 0.02, at 14 days was 1.79 ± 0.01, and at 21 days was 1.90±0.03. Mean remineralization in group II was 1.61 ± 0.01, 1.64 ± 0.02, and 1.73 ± 0.03 at 7, 14, and 21 days, respectively. Mean remineralization in group III was 1.62 ± 0.01, 1.65 ± 0.02, and 1.74 ± 0.05 at 7, 14, and 21 days, respectively. Mean remineralization in group IV was 1.59 ± 0.02, 1.62 ± 0.07, and 1.70 ± 0.09 at 7, 14, and 21 days, respectively. The maximum value was obtained on day 21. There was a significant difference in mean remineralization values between group I vs group II, group I vs group III, and group I vs group IV ( Conclusion: Self-assembling peptides showed maximum remineralization in tested specimens followed by CPP-ACP, SDF, and NovaMin-containing toothpaste. Clinical significance: CPP-ACP, SDF, and NovaMin-containing toothpaste can be indicated for remineralization of initial caries in clinical use. |
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MeSH term(s) | Caseins ; Dental Enamel ; Fluorides, Topical ; Glass ; Quaternary Ammonium Compounds ; Silver Compounds ; Tooth Remineralization |
Chemical Substances | Caseins ; Fluorides, Topical ; NovaMin ; Quaternary Ammonium Compounds ; Silver Compounds ; casein phosphopeptide-amorphous calcium phosphate nanocomplex ; silver diamine fluoride (DDU19UEV1Y) |
Language | English |
Publishing date | 2021-04-01 |
Publishing country | India |
Document type | Journal Article |
ISSN | 1526-3711 |
ISSN (online) | 1526-3711 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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