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  1. Book ; Thesis: Einfluss der Oberflächenmodifikation von vollkeramischen Dentalimplantaten auf die Wärmeentwicklung bei der Insertion in den Knochen

    König, Eugenie

    2015  

    Author's details vorgelegt von Eugenie König aus Taschkent
    Language German
    Size 241 Seiten, Illustrationen
    Publishing place Frankfurt am Main
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Johann Wolfgang Goethe-Universität Frankfurt am Main, 2016
    HBZ-ID HT019037628
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 D 710 order for loan Magazin

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  2. Article: Anatomical and Morphological Structure of the Skull of a Juvenile Specimen of

    Kłys, Grzegorz / Koenig, Elżbieta

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 8

    Abstract: Few studies analyze the morphology and anatomy of the bat skull, and most of them are incomplete. Some of the difficulties stem from the fact that, in the representatives of the order Chiroptera, the interosseous sutures disappear by fusing together ... ...

    Abstract Few studies analyze the morphology and anatomy of the bat skull, and most of them are incomplete. Some of the difficulties stem from the fact that, in the representatives of the order Chiroptera, the interosseous sutures disappear by fusing together before active flight begins, which takes place over only a few months. This study presents a detailed morphological and anatomical description of the skull of a juvenile specimen of
    Language English
    Publishing date 2024-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14081225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Endothelialer Mikrochimärismus nach Lebertransplantation

    König, Evelyn

    eine semiquantitative Analyse von Leberstanzbiopsien

    2008  

    Author's details vorgelegt von Evelyn König
    Language German
    Size 65 Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2010
    HBZ-ID HT016461712
    Database Catalogue ZB MED Medicine, Health

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    2010 E 2448 order for loan Magazin

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  4. Article: Frühe Hilfen digital bekannt machen - Elternansprache über Instagram

    König, Elena

    Forum Sexualaufklärung und Familienplanung

    2022  Volume -, Issue 1, Digitalisierung in der Beratung und Prävention, Page(s) 33

    Language German
    Document type Article
    ZDB-ID 1473859-4
    ISSN 2192-2152
    Database Current Contents Medicine

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    Zs.A 7003: Show issues Location:
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  5. Article: Frühe Hilfen digital bekannt machen - Elternansprache über Instagram

    König, Elena

    Forum Sexualaufklärung und Familienplanung

    2022  Volume -, Issue 1, Digitalisierung in der Beratung und Prävention, Page(s) 33

    Language German
    Document type Article
    ZDB-ID 1473859-4
    ISSN 2192-2152
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7003: Show issues Location:
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  6. Article ; Online: Treatment options for multidrug-resistant Gram-negatives in urinary tract infections.

    Zollner-Schwetz, Ines / König, Elisabeth

    Current opinion in urology

    2023  Volume 33, Issue 3, Page(s) 173–179

    Abstract: Purpose of review: Infections due to multidrug-resistant (MDR) Gram-negative bacteria are challenging to treat because of limited treatment options and potential side effects of less frequently used anti-infectives. In the past few years, several new ... ...

    Abstract Purpose of review: Infections due to multidrug-resistant (MDR) Gram-negative bacteria are challenging to treat because of limited treatment options and potential side effects of less frequently used anti-infectives. In the past few years, several new antimicrobial agents effective against MDR Gram-negatives have become available. This review focuses on the treatment options for complicated urinary tract infections (cUTIs) caused by MDR Gram-negatives.
    Recent findings: The novel combinations, betalactam or carbapenem and betalactamase inhibitor, ceftazidime/avibactam and meropenem/vaborbactam, are effective for infections caused by KPC-carbapenemase-producing pathogens. Imipenem/relebactam, another carbapenem/betalactamase inhibitor combination, has been approved for the treatment of cUTI. However, data on the efficacy of imipenem/relebactam against carbapenem-resistant pathogens is still limited. Ceftolozane/tazobactam is mainly used for the treatment of MDR Pseudomonas aeruginosa infections. For the treatment of cUTI caused by extended-spectrum betalactamases producing Enterobacterales aminoglycosides or intravenous fosfomycin should be considered.
    Summary: To ensure prudent use and to avoid the development of resistance to novel anti-infective substances, an interdisciplinary approach, including urologists, microbiologists, and infectious disease physicians, is strongly advised.
    MeSH term(s) Humans ; Gram-Negative Bacterial Infections/drug therapy ; Gram-Negative Bacterial Infections/chemically induced ; Anti-Bacterial Agents/adverse effects ; Urinary Tract Infections/drug therapy ; beta-Lactamase Inhibitors/pharmacology ; beta-Lactamase Inhibitors/therapeutic use ; Carbapenems/pharmacology ; Carbapenems/therapeutic use ; Imipenem/therapeutic use
    Chemical Substances relebactam (Y1MYA2UHFL) ; Anti-Bacterial Agents ; beta-Lactamase Inhibitors ; Carbapenems ; Imipenem (71OTZ9ZE0A)
    Language English
    Publishing date 2023-03-02
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000001084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3345: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Ultrasound-assisted catheter-directed thrombolysis in a patient with COVID-19 infection and bilateral intermediate-to-high-risk pulmonary embolism: a case report.

    Korosoglou, Grigorios / Mouselimis, Dimitrios / Koenig, Elke / Konstantinides, Stavros

    European heart journal. Case reports

    2024  Volume 8, Issue 1, Page(s) ytad628

    Abstract: Background: Acute pulmonary embolism (PE) is a common cardiovascular disorder, potentially associated with high morbidity and mortality rates.: Case summary: Herein, we report on a patient with COVID-19 infection and bilateral PE, who presented after ...

    Abstract Background: Acute pulmonary embolism (PE) is a common cardiovascular disorder, potentially associated with high morbidity and mortality rates.
    Case summary: Herein, we report on a patient with COVID-19 infection and bilateral PE, who presented after cardiovascular resuscitation with return of spontaneous circulation. Initially, an acute coronary syndrome was suspected but bedside echocardiography showed dilatation of the right ventricle (RV) and RV dysfunction, helping to establish the diagnosis of acute intermediate-to-high-risk PE, which was subsequently confirmed by contrast-enhanced computed tomography pulmonary angiography. The patient was successfully treated using low-dose (12 mg of tissue plasminogen) ultrasound-assisted catheter-directed thrombolysis, which resulted in prompt clinical improvement and reversal of RV dysfunction without bleeding complications.
    Discussion: This case demonstrates the importance of echocardiography for the differential diagnosis of PE and of catheter-directed thrombolysis for its treatment in patients with intermediate-to-high-risk and high-risk PEs.
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytad628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Frühe Hilfen digital bekannt machen - Elternansprache über Instagram

    König, Elena

    Forum Sexualaufklärung und Familienplanung

    2021  Volume -, Issue 2, Digitalisierung in Beratung und Prävention, Page(s) 33

    Language German
    Document type Article
    ZDB-ID 1473859-4
    ISSN 2192-2152
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7003: Show issues Location:
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  9. Article ; Online: Impact of the inaccessible genome on genotype imputation and genome-wide association studies.

    König, Eva / Mitchell, Jonathan Stewart / Filosi, Michele / Fuchsberger, Christian

    Human molecular genetics

    2024  

    Abstract: Genotype imputation is widely used in genome-wide association studies (GWAS). However, both the genotyping chips and imputation reference panels are dependent on next-generation sequencing (NGS). Due to the nature of NGS, some regions of the genome are ... ...

    Abstract Genotype imputation is widely used in genome-wide association studies (GWAS). However, both the genotyping chips and imputation reference panels are dependent on next-generation sequencing (NGS). Due to the nature of NGS, some regions of the genome are inaccessible to sequencing. To date, there has been no complete evaluation of these regions and their impact on the identification of associations in GWAS remains unclear. In this study, we systematically assess the extent to which variants in inaccessible regions are underrepresented on genotyping chips and imputation reference panels, in GWAS results and in variant databases. We also determine the proportion of genes located in inaccessible regions and compare the results across variant masks defined by the 1000 Genomes Project and the TOPMed program. Overall, fewer variants were observed in inaccessible regions in all categories analyzed. Depending on the mask used and normalized for region size, only 4%-17% of the genotyped variants are located in inaccessible regions and 52 to 581 genes were almost completely inaccessible. From the Cooperative Health Research in South Tyrol (CHRIS) study, we present a case study of an association located in an inaccessible region that is driven by genotyped variants and cannot be reproduced by imputation in GRCh37. We conclude that genotyping, NGS, genotype imputation and downstream analyses such as GWAS and fine mapping are systematically biased in inaccessible regions, due to missed variants and spurious associations. To help researchers assess gene and variant accessibility, we provide an online application (https://gab.gm.eurac.edu).
    Language English
    Publishing date 2024-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1108742-0
    ISSN 1460-2083 ; 0964-6906
    ISSN (online) 1460-2083
    ISSN 0964-6906
    DOI 10.1093/hmg/ddae062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3469: Show issues Location:
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  10. Article: Stellenwert der Blutkultur bei Endokarditis: nach wie vor das wichtigste mikrobiologische Endokarditis-Diagnosekriterium

    Krause, R. / König, E. / Valentin, T. / Zollner-Schwetz, I.

    Universum Innere Medizin

    2023  Volume -, Issue 3, Page(s) 30

    Language German
    Document type Article
    ZDB-ID 2475266-6
    ISSN 1607-8861
    Database Current Contents Medicine

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    Zs.A 7126: Show issues Location:
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