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Article: Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy.

Brody, Steven L / Pan, Jiehong / Huang, Tao / Xu, Jian / Xu, Huihui / Koenitizer, Jeffrey / Brennan, Steven K / Nanjundappa, Rashmi / Saba, Thomas G / Berical, Andrew / Hawkins, Finn J / Wang, Xiangli / Zhang, Rui / Mahjoub, Moe R / Horani, Amjad / Dutcher, Susan K

bioRxiv : the preprint server for biology

2024  

Abstract: Motile cilia have essential cellular functions in development, reproduction, and homeostasis. Genetic causes for motile ciliopathies have been identified, but the consequences on cellular functions beyond impaired motility remain unknown. Variants ... ...

Abstract Motile cilia have essential cellular functions in development, reproduction, and homeostasis. Genetic causes for motile ciliopathies have been identified, but the consequences on cellular functions beyond impaired motility remain unknown. Variants in
Language English
Publishing date 2024-03-21
Publishing country United States
Document type Preprint
DOI 10.1101/2024.03.20.585965
Database MEDical Literature Analysis and Retrieval System OnLINE

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