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  1. Book ; Online: Deeltjesfysica

    Koffeman, Els

    onvoorstelbare waarnemingen

    (VOR Natuurwetenschappen, Wiskunde en Informatica)

    2009  

    Abstract: In een 27 km lange tunnel onder de grond in de buurt van Genève wordt na een jarenlange voorbereiding de laatste hand gelegd aan een deeltjesversneller. De versneller is gemaakt om protonen met elkaar in botsing te brengen. De protonen krijgen een ... ...

    Institution ebrary, Inc
    Author's details Els Koffeman
    Series title VOR Natuurwetenschappen, Wiskunde en Informatica
    Abstract In een 27 km lange tunnel onder de grond in de buurt van Genève wordt na een jarenlange voorbereiding de laatste hand gelegd aan een deeltjesversneller. De versneller is gemaakt om protonen met elkaar in botsing te brengen. De protonen krijgen een ongeëvenaarde snelheid en op deze manier zullen de botsingen inzicht verschaffen in het diepst van de materie. Structuur der materie op een afstandschaal van 0.000000000000000001 meter ofwel een attometer. Onvoorstelbaar klein? Els Koffeman is bijzonder hoogleraar instrumentatie in de deeltjesfysica aan de Universiteit van Amsterdam en is werkzaam bi
    Keywords Particle accelerators ; Particles (Nuclear physics)
    Language Dutch
    Size Online-Ressource (18 p)
    Publisher Amsterdam University Press
    Publishing place Amsterdam
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9789056295332 ; 9056295330
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Proton Radiography With Timepix Based Time Projection Chambers.

    Biegun, Aleksandra K / Visser, Jan / Klaver, Tom / Ghazanfari, Nafiseh / van Goethem, Marc-Jan / Koffeman, Els / van Beuzekom, Martin / Brandenburg, Sytze

    IEEE transactions on medical imaging

    2016  Volume 35, Issue 4, Page(s) 1099–1105

    Abstract: The development of a proton radiography system to improve the imaging of patients in proton beam therapy is described. The system comprises gridpix based time projection chambers, which are based on the Timepix chip designed by the Medipix collaboration, ...

    Abstract The development of a proton radiography system to improve the imaging of patients in proton beam therapy is described. The system comprises gridpix based time projection chambers, which are based on the Timepix chip designed by the Medipix collaboration, for tracking the protons. This type of detector was chosen to have minimal impact on the actual determination of the proton tracks by the tracking detectors. To determine the residual energy of the protons, a BaF 2 crystal with a photomultiplier tube is used. We present data taken in a feasibility experiment with phantoms that represent tissue equivalent materials found in the human body. The obtained experimental results show a good agreement with the performed simulations.
    MeSH term(s) Image Processing, Computer-Assisted/methods ; Phantoms, Imaging ; Protons ; Radiography/instrumentation ; Radiography/methods
    Chemical Substances Protons
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 622531-7
    ISSN 1558-254X ; 0278-0062
    ISSN (online) 1558-254X
    ISSN 0278-0062
    DOI 10.1109/TMI.2015.2509175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The optimal balance between quality and efficiency in proton radiography imaging technique at various proton beam energies: A Monte Carlo study.

    Biegun, A K / van Goethem, M-J / van der Graaf, E R / van Beuzekom, M / Koffeman, E N / Nakaji, T / Takatsu, J / Visser, J / Brandenburg, S

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

    2017  Volume 41, Page(s) 141–146

    Abstract: Proton radiography is a novel imaging modality that allows direct measurement of the proton energy loss in various tissues. Currently, due to the conversion of so-called Hounsfield units from X-ray Computed Tomography (CT) into relative proton stopping ... ...

    Abstract Proton radiography is a novel imaging modality that allows direct measurement of the proton energy loss in various tissues. Currently, due to the conversion of so-called Hounsfield units from X-ray Computed Tomography (CT) into relative proton stopping powers (RPSP), the uncertainties of RPSP are 3-5% or higher, which need to be minimized down to 1% to make the proton treatment plans more accurate. In this work, we simulated a proton radiography system, with position-sensitive detectors (PSDs) and a residual energy detector (RED). The simulations were built using Geant4, a Monte Carlo simulation toolkit. A phantom, consisting of several materials was placed between the PSDs of various Water Equivalent Thicknesses (WET), corresponding to an ideal detector, a gaseous detector, silicon and plastic scintillator detectors. The energy loss radiograph and the scattering angle distributions of the protons were studied for proton beam energies of 150MeV, 190MeV and 230MeV. To improve the image quality deteriorated by the multiple Coulomb scattering (MCS), protons with small angles were selected. Two ways of calculating a scattering angle were considered using the proton's direction and position. A scattering angle cut of 8.7mrad was applied giving an optimal balance between quality and efficiency of the radiographic image. For the three proton beam energies, the number of protons used in image reconstruction with the direction method was half the number of protons kept using the position method.
    Language English
    Publishing date 2017-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1122650-x
    ISSN 1724-191X ; 1120-1797
    ISSN (online) 1724-191X
    ISSN 1120-1797
    DOI 10.1016/j.ejmp.2017.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Identification and manipulation of antigen specific T-cells with artificial antigen presenting cells.

    Koffeman, Eva / Keogh, Elissa / Klein, Mark / Prakken, Berent / Albani, Salvatore

    Methods in molecular medicine

    2007  Volume 136, Page(s) 69–86

    Abstract: T-cells specific for a particular antigen represent a small percentage of the overall T-cell population. Detecting the presence of antigen specific T-cells in patients, animal models or populations of cultured cells has presented a challenge to ... ...

    Abstract T-cells specific for a particular antigen represent a small percentage of the overall T-cell population. Detecting the presence of antigen specific T-cells in patients, animal models or populations of cultured cells has presented a challenge to researchers. The T-cell capture method described here utilizes a truly artificial method of antigen presentation and requires only 50,000 cells for the detection of the major histomcompatibility complex (MHC) class II and antigen restricted T-cells. With this method, liposomes, prepared with readily available materials, are loaded with neutravidin "rafts" comprised of MHC/peptide complexes, anti-CD28, a costimulatory molecule, and anti-LFA-1, an adhesion molecule. These artificial APCs are easily manipulated to include any MHC, antibodies to cell surface markers and/or costimulatory signals of interest thereby enabling not only T-cell identification but also the manipulation of mechanisms of T-cell activation.
    MeSH term(s) Animals ; Antigen-Presenting Cells/immunology ; Antigens/immunology ; Cell Separation/methods ; Flow Cytometry/methods ; Genes, MHC Class II ; Humans ; Lipids/chemistry ; Liposomes/metabolism ; Peptides/immunology ; Peptides/isolation & purification ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology
    Chemical Substances Antigens ; Lipids ; Liposomes ; Peptides
    Language English
    Publishing date 2007-10-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1543-1894
    ISSN 1543-1894
    DOI 10.1007/978-1-59745-402-5_6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Periodic fever as a presenting sign of childhood acute lymphoblastic leukaemia.

    Koffeman, E C / Wulffraat, N M / Bruin, M / Hogeman, P H G / Frenkel, J

    Rheumatology (Oxford, England)

    2005  Volume 44, Issue 12, Page(s) 1583–1584

    MeSH term(s) Anemia/etiology ; Child ; Familial Mediterranean Fever/etiology ; Female ; Humans ; Pain/etiology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications
    Language English
    Publishing date 2005-12
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1464822-2
    ISSN 1462-0332 ; 1462-0324
    ISSN (online) 1462-0332
    ISSN 1462-0324
    DOI 10.1093/rheumatology/kei089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Improvement of efficiency and occupancy performance by cluster threshold in si-strip detector readout

    Cesura, G / Koffeman, E / Lutz, G

    (MPI-PhE ; 96-11)

    1996  

    Author's details G. Cesura, E. Koffeman and G. Lutz
    Series title MPI-PhE ; 96-11
    Language English
    Size 14 S, graph. Darst, 30 cm
    Publisher Max-Planck-Inst. für Physik
    Publishing place München
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article ; Online: Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis.

    Roord, Sarah T A / Zonneveld-Huijssoon, Evelien / Le, Tho / Yung, Gisella Puga / Koffeman, Eva / Ronaghy, Arash / Ghahramani, Negar / Lanza, Paola / Billetta, Rosario / Prakken, Berent J / Albani, Salvatore

    PloS one

    2006  Volume 1, Page(s) e87

    Abstract: Innate and adaptive immunity contribute to the pathogenesis of autoimmune arthritis by generating and maintaining inflammation, which leads to tissue damage. Current biological therapies target innate immunity, eminently by interfering with single pro- ... ...

    Abstract Innate and adaptive immunity contribute to the pathogenesis of autoimmune arthritis by generating and maintaining inflammation, which leads to tissue damage. Current biological therapies target innate immunity, eminently by interfering with single pro-inflammatory cytokine pathways. This approach has shown excellent efficacy in a good proportion of patients with Rheumatoid Arthritis (RA), but is limited by cost and side effects. Adaptive immunity, particularly T cells with a regulatory function, plays a fundamental role in controlling inflammation in physiologic conditions. A growing body of evidence suggests that modulation of T cell function is impaired in autoimmunity. Restoration of such function could be of significant therapeutic value. We have recently demonstrated that epitope-specific therapy can restore modulation of T cell function in RA patients. Here, we tested the hypothesis that a combination of anti-cytokine and epitope-specific immunotherapy may facilitate the control of autoimmune inflammation by generating active T cell regulation. This novel combination of mucosal tolerization to a pathogenic T cell epitope and single low dose anti-TNFalpha was as therapeutically effective as full dose anti-TNFalpha treatment. Analysis of the underlying immunological mechanisms showed induction of T cell immune deviation.
    MeSH term(s) Amino Acid Sequence ; Animals ; Antigens, Bacterial/genetics ; Antigens, Bacterial/immunology ; Arthritis, Experimental/immunology ; Arthritis, Experimental/pathology ; Arthritis, Experimental/therapy ; Autoimmunity ; Base Sequence ; Chaperonin 60/genetics ; Chaperonin 60/immunology ; Cytokines/antagonists & inhibitors ; Cytokines/genetics ; Cytokines/metabolism ; DNA Primers/genetics ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/immunology ; Etanercept ; Hindlimb/pathology ; Humans ; Immunity, Mucosal ; Immunoglobulin G/administration & dosage ; Immunotherapy/methods ; Immunotherapy, Adoptive ; Male ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/immunology ; Rats ; Rats, Inbred Lew ; Receptors, Tumor Necrosis Factor/administration & dosage ; T-Lymphocytes/immunology ; T-Lymphocytes, Regulatory/immunology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Antigens, Bacterial ; Chaperonin 60 ; Cytokines ; DNA Primers ; Epitopes, T-Lymphocyte ; Immunoglobulin G ; Receptors, Tumor Necrosis Factor ; Tumor Necrosis Factor-alpha ; Etanercept (OP401G7OJC)
    Language English
    Publishing date 2006-12-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0000087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: The Control Unit of the KM3NeT Data Acquisition System

    Aiello, S. / Ameli, F. / Andre, M. / Androulakis, G. / Anghinolfi, M. / Anton, G. / Ardid, M. / Aublin, J. / Bagatelas, C. / Barbarino, G. / Baret, B. / Pree, S. Basegmez du / Bendahman, M. / Berbee, E. / Berg, A. M. van den / Bertin, V. / Biagi, S. / Biagioni, A. / Bissinger, M. /
    Boumaaza, J. / Bourret, S. / Bouta, M. / Bouvet, G. / Bouwhuis, M. / Bozza, C. / Branzas, H. / Bruchner, M. / Bruijn, R. / Brunner, J. / Buis, E. / Buompane, R. / Busto, J. / Calvo, D. / Capone, A. / Celli, S. / Chabab, M. / Chau, N. / Cherubini, S. / Chiarella, V. / Chiarusi, T. / Circella, M. / Cocimano, R. / Coelho, J. A. B. / Coleiro, A. / Molla, M. Colomer / Coniglione, R. / Coyle, P. / Creusot, A. / Cuttone, G. / D'Onofrio, A. / Dallier, R. / De Palma, M. / Di Palma, I. / Díaz, A. F. / Diego-Tortosa, D. / Distefano, C. / Domi, A. / Donà, R. / Donzaud, C. / Dornic, D. / Dörr, M. / Durocher, M. / Eberl, T. / Bojaddaini, I. El / Eljarrari, H. / Elsaesser, D. / Enzenhöfer, A. / Fermani, P. / Ferrara, G. / Filipovic, M. D. / Franco, A. / Fusco, L. A. / Gal, T. / Soto, A. Garcia / Garufi, F. / Gialanella, L. / Giorgio, E. / Gozzini, S. R. / Gracia, R. / Graf, K. / Grasso, D. / Grégoire, T. / Grella, G. / Guderian, D. / Guidi, C. / Hallmann, S. / Hamdaoui, H. / van Haren, H. / Heijboer, A. / Hekalo, A. / Hernández-Rey, J. J. / Hofestädt, J. / Huang, F. / Illuminati, G. / James, C. W. / de Jong, M. / de Jong, P. / Kadler, M. / Kalaczynski, P. / Kalekin, O. / Katz, U. F. / Chowdhury, N. R. Khan / van der Knaap, F. / Koffeman, E. N. / Kooijman, P. / Kouchner, A. / Kulikovskiy, V. / Lahmann, R. / Larosa, G. / Breton, R. Le / Leone, F. / Leonora, E. / Levi, G. / Lincetto, M. / Lonardo, A. / Longhitano, F. / Lopez-Coto, D. / Maggi, G. / Manczak, J. / Mannheim, K. / Margiotta, A. / Marinelli, A. / Markou, C. / Martignac, G. / Martin, L. / Martínez-Mora, J. A. / Martini, A. / Marzaioli, F. / Mazzou, S. / Mele, R. / Melis, K. W. / Migliozzi, P. / Migneco, E. / Mijakowski, P. / Miranda, L. S. / Mollo, C. M. / Morganti, M. / Moser, M. / Moussa, A. / Muller, R. / Musumeci, M. / Nauta, L. / Navas, S. / Nicolau, C. A. / Nielsen, C. / Fearraigh, B. O' / Organokov, M. / Orlando, A. / Panagopoulos, V. / Papalashvili, G. / Papaleo, R. / Pastore, C. / Pavalas, G. E. / Pellegrino, C. / Perrin-Terrin, M. / Piattelli, P. / Pieterse, C. / Pikounis, K. / Pisanti, O. / Poirè, C. / Polydefki, G. / Popa, V. / Post, M. / Pradier, T. / Puhlhofer, G. / Pulvirenti, S. / Quinn, L. / Raffaelli, F. / Randazzo, N. / Rapicavoli, A. / Razzaque, S. / Real, D. / Reck, S. / Reubelt, J. / Riccobene, G. / Richer, M. / Rigalleau, L. / Rovelli, A. / Salvadori, I. / Samtleben, D. F. E. / Losa, A. Sánchez / Sanguineti, M. / Santangelo, A. / Santonocito, D. / Sapienza, P. / Schnabel, J. / Sciacca, V. / Seneca, J. / Sgura, I. / Shanidze, R. / Sharma, A. / Simeone, F. / Sinopoulou, A. / Spisso, B. / Spurio, M. / Stavropoulos, D. / Steijger, J. / Stellacci, S. M. / Strandberg, B. / Stransky, D. / Taiuti, M. / Tayalati, Y. / Tenllado, E. / Thakore, T. / Tingay, S. / Tzamariudaki, E. / Tzanetatos, D. / Van Elewyck, V. / Vannoye, G. / Versari, F. / Viola, S. / Vivolo, D. / de Wasseige, G. / Wilms, J. / Wojaczynski, R. / de Wolf, E. / Zaborov, D. / Zegarelli, A. / Zornoza, J. D. / Zúñiga, J.

    2019  

    Abstract: The KM3NeT Collaboration runs a multi-site neutrino observatory in the Mediterranean Sea. Water Cherenkov particle detectors, deep in the sea and far off the coasts of France and Italy, are already taking data while incremental construction progresses. ... ...

    Abstract The KM3NeT Collaboration runs a multi-site neutrino observatory in the Mediterranean Sea. Water Cherenkov particle detectors, deep in the sea and far off the coasts of France and Italy, are already taking data while incremental construction progresses. Data Acquisition Control software is operating off-shore detectors as well as testing and qualification stations for their components. The software, named Control Unit, is highly modular. It can undergo upgrades and reconfiguration with the acquisition running. Interplay with the central database of the Collaboration is obtained in a way that allows for data taking even if Internet links fail. In order to simplify the management of computing resources in the long term, and to cope with possible hardware failures of one or more computers, the KM3NeT Control Unit software features a custom dynamic resource provisioning and failover technology, which is especially important for ensuring continuity in case of rare transient events in multi-messenger astronomy. The software architecture relies on ubiquitous tools and broadly adopted technologies and has been successfully tested on several operating systems.
    Keywords Astrophysics - Instrumentation and Methods for Astrophysics ; High Energy Physics - Experiment
    Subject code 303
    Publishing date 2019-09-30
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Deep sea tests of a prototype of the KM3NeT digital optical module

    Adrián-Martínez, S. / Ageron, M. / Aharonian, F. / Aiello, S. / Albert, A. / Ameli, F. / Anassontzis, E. G. / Anghinolfi, M. / Anton, G. / Anvar, S. / Ardid, M. / de Asmundis, R. / Balasi, K. / Band, H. / Barbarino, G. / Barbarito, E. / Barbato, F. / Baret, B. / Baron, S. /
    Belias, A. / Berbee, E. / Berg, A. M. van den / Berkien, A. / Bertin, V. / Beurthey, S. / van Beveren, V. / Beverini, N. / Biagi, S. / Bianucci, S. / Billault, M. / Birbas, A. / Rookhuizen, H. Boer / Bormuth, R. / Bouche, V. / Bouhadef, B. / Bourlis, G. / Bouwhuis, M. / Bozza, C. / Bruijn, R. / Brunner, J. / Cacopardo, G. / Caillat, L. / Calamai, M. / Calvo, D. / Capone, A. / Caramete, L. / Caruso, F. / Cecchini, S. / Ceres, A. / Cereseto, R. / Champion, C. / Chateau, F. / Chiarusi, T. / Christopoulou, B. / Circella, M. / Classen, L. / Cocimano, R. / Colonges, S. / Coniglione, R. / Cosquer, A. / Costa, M. / Coyle, P. / Creusot, A. / Curtil, C. / Cuttone, G. / D'Amato, C. / D'Amico, A. / De Bonis, G. / De Rosa, G. / Deniskina, N. / Destelle, J. -J. / Distefano, C. / Donzaud, C. / Dornic, D. / Dorosti-Hasankiadeh, Q. / Drakopoulou7, E. / Drouhin, D. / Drury, L. / Durand, D. / Eberl, T. / Eleftheriadis, C. / Elsaesser, D. / Enzenhofer, A. / Fermani, P. / Fusco, L. A. / Gajana, D. / Gal, T. / Galata, S. / Gallo, F. / Garufi, F. / Gebyehu, M. / Giordano, V. / Gizani, N. / Ruiz, R. Gracia / Graf, K. / Grasso, R. / Grella, G. / Grmek, A. / Habel, R. / van Haren, H. / Heid, T. / Heijboer, A. / Heine, E. / Henry, S. / Hernandez-Rey, J. J. / Herold, B. / Hevinga, M. A. / van der Hoek, M. / Hofestadt, J. / Hogenbirk, J. / Hugon, C. / Hosl, J. / Imbesi, M. / James, C. / Jansweijer, P. / Jochum, J. / de Jong, M. / Kadler, M. / Kalekin, O. / Kappes, A. / Kappos, E. / Katz, U. / Kavatsyuk, O. / Keller, P. / Kieft, G. / Koffeman, E. / Kok, H. / Kooijman, P. / Koopstra, J. / Korporaal, A. / Kouchner, A. / Koutsoukos, S. / Kreykenbohm, I. / Kulikovskiy, V. / Lahmann, R. / Lamare, P. / Larosa, G. / Lattuada, D. / Provost, H. Le / Leisos, A. / Lenis, D. / Leonora, E. / Clark, M. Lindsey / Liolios, A. / Alvarez, C. D. Llorens / Lohner, H. / Presti, D. Lo / Louis, F. / Maccioni, E. / Mannheim, K. / Manolopoulos, K. / Margiotta, A. / Maris, O. / Markou, C. / Martinez-Mora, J. A. / Martini, A. / Masullo, R. / Michael, T. / Migliozzi, P. / Migneco, E. / Miraglia, A. / Mollo, C. / Mongelli, M. / Morganti, M. / Mos, S. / Moudden, Y. / Musico, P. / Musumeci, M. / Nicolaou, C. / Nicolau, C. A. / Orlando, A. / Orzelli, A. / Papageorgiou, K. / Papaikonomou, A. / Papaleo, R. / Pavalas, G. E. / Peek, H. / Pellegrino, C. / Pellegriti, M. G. / Perrina, C. / Petridou, C. / Piattelli, P. / Pikounis, K. / Popa, V. / Pradier, Th. / Priede, M. / Puhlhofer, G. / Pulvirenti, S. / Racca, C. / Raffaelli, F. / Randazzo, N. / Rapidis, P. A. / Razis, P. / Real, D. / Resvanis, L. / Reubelt, J. / Riccobene, G. / Rovelli, A. / Royon, J. / Saldana, M. / Samtleben, D. F. E. / Sanguineti, M. / Santangelo, A. / Sapienza, P. / Savvidis, I. / Schmelling, J. / Schnabel, J. / Sedita, M. / Seitz, T. / Sgura, I. / Simeone, F. / Siotis, I. / Sipala, V. / Solazzo, M. / Spitaleri, A. / Spurio, M. / Stavropoulos, G. / Steijger, J. / Stolarczyk, T. / Stransky, D. / Taiuti, M. / Terreni, G. / Tezier, D. / Theraube, S. / Thompson, L. F. / Timmer, P. / Trapierakis, H. I. / Trasatti, L. / Trovato, A. / Tselengidou, M. / Tsirigotis, A. / Tzamarias, S. / Tzamariudaki, E. / Vallage, B. / Van Elewyck, V. / Vermeulen, J. / Vernin, P. / Viola, S. / Vivolo, D. / Werneke, P. / Wiggers, L. / Wilms, J. / de Wolf, E. / van Wooning, R. H. L. / Yatkin, K. / Zachariadou, K. / Zonca, E. / Zornoza, J. D. / Zúñiga, J. / Zwart, A.

    2014  

    Abstract: The first prototype of a photo-detection unit of the future KM3NeT neutrino telescope has been deployed in the deep waters of the Mediterranean Sea. This digital optical module has a novel design with a very large photocathode area segmented by the use ... ...

    Abstract The first prototype of a photo-detection unit of the future KM3NeT neutrino telescope has been deployed in the deep waters of the Mediterranean Sea. This digital optical module has a novel design with a very large photocathode area segmented by the use of 31 three inch photomultiplier tubes. It has been integrated in the ANTARES detector for in-situ testing and validation. This paper reports on the first months of data taking and rate measurements. The analysis results highlight the capabilities of the new module design in terms of background suppression and signal recognition. The directionality of the optical module enables the recognition of multiple Cherenkov photons from the same $^{40}$K decay and the localization bioluminescent activity in the neighbourhood. The single unit can cleanly identify atmospheric muons and provide sensitivity to the muon arrival directions.
    Keywords Astrophysics - Instrumentation and Methods for Astrophysics ; Physics - Instrumentation and Detectors
    Subject code 621
    Publishing date 2014-05-05
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Inclusive K(S);(0)K(S);(0) resonance production in ep collisions at HERA.

    Chekanov, S / Derrick, M / Magill, S / Musgrave, B / Nicholass, D / Repond, J / Yoshida, R / Mattingly, M C K / Antonioli, P / Bari, G / Bellagamba, L / Boscherini, D / Bruni, A / Bruni, G / Cindolo, F / Corradi, M / Iacobucci, G / Margotti, A / Nania, R /
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    Physical review letters

    2008  Volume 101, Issue 11, Page(s) 112003

    Abstract: Inclusive K_{S};{0}K_{S};{0} production in ep collisions at the DESY ep collider HERA was studied with the ZEUS detector using an integrated luminosity of 0.5 fb;{-1}. Enhancements in the mass spectrum were observed and are attributed to the production ... ...

    Abstract Inclusive K_{S};{0}K_{S};{0} production in ep collisions at the DESY ep collider HERA was studied with the ZEUS detector using an integrated luminosity of 0.5 fb;{-1}. Enhancements in the mass spectrum were observed and are attributed to the production of f_{2}(1270)/a_{2};{0}(1320), f_{2};{'}(1525) and f_{0}(1710). Masses and widths were obtained using a fit which takes into account theoretical predictions based on SU(3) symmetry arguments, and are consistent with the Particle Data Group values. The f_{0}(1710) state, which has a mass consistent with a glueball candidate, was observed with a statistical significance of 5 standard deviations. However, if this state is the same as that seen in gammagamma-->K_{S};{0}K_{S};{0}, it is unlikely to be a pure glueball state.
    Language English
    Publishing date 2008-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.101.112003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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