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  1. Article ; Online: Letter to the Editor:

    Koh, Samuel Ji Quan / Sim, David Kheng Leng / Neo, Shirlyn Hui-Shan

    Journal of palliative medicine

    2023  Volume 26, Issue 7, Page(s) 893–895

    MeSH term(s) Humans ; Artificial Intelligence ; Heart Failure/therapy
    Language English
    Publishing date 2023-07-10
    Publishing country United States
    Document type Letter
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2023.0199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5440: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Residents' Report of COVID-19 Associated Training Disruptions, Stressors, and Opportunities During the Pandemic-The Singapore Experience.

    Koh, Samuel Ji Quan / Woon, Ting Hui / Fong, Warren / Kwan, Yu Heng / Lim, Swee Han / Lee, Jodie Ling Horng / Tan, Hak Koon

    Journal of graduate medical education

    2023  Volume 15, Issue 4, Page(s) 494–499

    Abstract: Background: The COVID-19 pandemic has disrupted residency training. Several studies have been performed to investigate the impact of the pandemic on residency training in Accreditation Council for Graduate Medical Education-International (ACGME-I)- ... ...

    Abstract Background: The COVID-19 pandemic has disrupted residency training. Several studies have been performed to investigate the impact of the pandemic on residency training in Accreditation Council for Graduate Medical Education-International (ACGME-I)-accredited institutions. However, these were either limited to certain specialties or failed to consider possible opportunities from the pandemic.
    Objective: To determine the stressors on residents as well as the opportunities that arose from the COVID-19 pandemic across multiple specialities in Singapore.
    Methods: A cross-sectional survey among SingHealth residents was conducted between July and September 2020. The survey assessed the balance between service and training during hospital postings, the pandemic's influence on examination and teaching, the psychological impact of the pandemic, the level of burnout, and the effect on morale of residents during the pandemic.
    Results: The response rate was 27.1% (253 of 934). Out of the 253 residents, 136 (53.8%) felt stressed during the pandemic. Concerns about family's health and safety pertaining to potential COVID-19 infection, progression in training, and completion of examinations were the top 3 stressors. One-hundred and three residents (40.7%) had their training disrupted either by being placed in an interim posting not part of their residency requirements or being deployed to care for patients with COVID-19. Although administrative support and information for virtual teaching were sufficient, only 108 (42.7%) agreed it had the same value as face-to-face sessions. Despite the challenges, 179 (70.8%) thought that experiencing this crisis provided more meaning in their career.
    Conclusions: The COVID-19 pandemic has brought about challenges and learning opportunities for residents.
    MeSH term(s) Humans ; COVID-19 ; Cross-Sectional Studies ; Internship and Residency ; Pandemics ; Singapore
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2578612-X
    ISSN 1949-8357 ; 1949-8357
    ISSN (online) 1949-8357
    ISSN 1949-8357
    DOI 10.4300/JGME-D-22-00569.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical outcomes in end stage renal disease on dialysis and severe coronary artery disease: A real-world study.

    Koh, Samuel Ji Quan / Yap, Jonathan / Jiang, Yilin / Sng, Gerald Gui Ren / Low, Yi Hua / Lau, Yee How / Sin, Yoong Kong Kenny / Yeo, Khung Keong

    International journal of cardiology

    2023  Volume 378, Page(s) 105–110

    Abstract: Background: The optimal management of patients with end-stage renal disease (ESRD) on dialysis with severe coronary artery disease (CAD) has not been determined.: Methods: Between 2013 and 2017, all patients with ESRD on dialysis who had left main ( ... ...

    Abstract Background: The optimal management of patients with end-stage renal disease (ESRD) on dialysis with severe coronary artery disease (CAD) has not been determined.
    Methods: Between 2013 and 2017, all patients with ESRD on dialysis who had left main (LM) disease, triple vessel disease (TVD) and/or severe CAD for consideration of coronary artery bypass graft (CABG) were included. Patients were divided into 3 groups based on final treatment modality: CABG, percutaneous coronary intervention (PCI), optimal medical therapy (OMT). Outcome measures include in-hospital, 180-day, 1-year and overall mortality and major adverse cardiac events (MACE).
    Results: In total, 418 patients were included (CABG 11.0%, PCI 65.6%, OMT 23.4%). Overall, 1-year mortality and MACE rates were 27.5% and 55.0% respectively. Patients who underwent CABG were significantly younger, more likely to have LM disease and have no prior heart failure. In this non-randomized setting, treatment modality did not impact on 1-year mortality, although the CABG group had significantly lower 1-year MACE rates (CABG 32.6%, PCI 57.3%, OMT 59.2%; CABG vs. OMT p < 0.01, CABG vs. PCI p < 0.001). Independent predictors of overall mortality include STEMI presentation (HR 2.31, 95% CI 1.38-3.86), prior heart failure (HR 1.84, 95% CI 1.22-2.75), LM disease (HR 1.71, 95% CI 1.26-2.31), NSTE-ACS presentation (HR 1.40, 95% CI 1.03-1.91) and increased age (HR 1.02, 95% CI 1.01-1.04).
    Conclusion: Treatment decisions for patients with severe CAD with ESRD on dialysis are complex. Understanding independent predictors of mortality and MACE in specific treatment subgroups may provide valuable insights into the selection of optimal treatment options.
    MeSH term(s) Humans ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/surgery ; Renal Dialysis ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Heart Failure/etiology
    Language English
    Publishing date 2023-02-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.02.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Subacute thyroiditis associated with COVID-19.

    Mattar, Shaikh Abdul Matin / Koh, Samuel Ji Quan / Rama Chandran, Suresh / Cherng, Benjamin Pei Zhi

    BMJ case reports

    2020  Volume 13, Issue 8

    Abstract: We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together ...

    Abstract We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together with consistent ultrasonographic evidence suggesting subacute thyroiditis. Treatment with corticosteroids resulted in rapid clinical resolution. This case illustrates that subacute thyroiditis associated with viruses such as SARS-CoV-2 should be recognised as a complication of COVID-19 and considered as a differential diagnosis when infected patients present with tachycardia without evidence of progression of COVID-19 illness.
    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Diagnosis, Differential ; Glucocorticoids/therapeutic use ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Prednisolone/therapeutic use ; SARS-CoV-2 ; Thyroiditis, Subacute/diagnosis ; Thyroiditis, Subacute/diagnostic imaging ; Thyroiditis, Subacute/drug therapy ; Thyroiditis, Subacute/virology ; Treatment Outcome ; Ultrasonography
    Chemical Substances Glucocorticoids ; Prednisolone (9PHQ9Y1OLM)
    Keywords covid19
    Language English
    Publishing date 2020-08-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-237336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Subacute thyroiditis associated with COVID-19

    Mattar, Shaikh Abdul Matin / Koh, Samuel Ji Quan / Rama Chandran, Suresh / Cherng, Benjamin Pei Zhi

    BMJ case reports

    Abstract: We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together ...

    Abstract We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together with consistent ultrasonographic evidence suggesting subacute thyroiditis. Treatment with corticosteroids resulted in rapid clinical resolution. This case illustrates that subacute thyroiditis associated with viruses such as SARS-CoV-2 should be recognised as a complication of COVID-19 and considered as a differential diagnosis when infected patients present with tachycardia without evidence of progression of COVID-19 illness.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #742203
    Database COVID19

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  6. Article ; Online: Subacute thyroiditis associated with COVID-19

    Mattar, Shaikh Abdul Matin / Koh, Samuel Ji Quan / Rama Chandran, Suresh / Cherng, Benjamin Pei Zhi

    BMJ Case Reports

    2020  Volume 13, Issue 8, Page(s) e237336

    Abstract: We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together ...

    Abstract We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection. The patient presented with tachycardia, anterior neck pain and thyroid function tests revealing hyperthyroidism together with consistent ultrasonographic evidence suggesting subacute thyroiditis. Treatment with corticosteroids resulted in rapid clinical resolution. This case illustrates that subacute thyroiditis associated with viruses such as SARS-CoV-2 should be recognised as a complication of COVID-19 and considered as a differential diagnosis when infected patients present with tachycardia without evidence of progression of COVID-19 illness.
    Keywords covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ISSN 1757-790X
    DOI 10.1136/bcr-2020-237336
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Impact of aortic annular size and valve type on haemodynamics and clinical outcomes after transcatheter aortic valve implantation.

    Koh, Samuel Ji Quan / Yap, Jonathan / Jiang, Yilin / Tay, Julian Cheong Kiat / Quah, Kevin Kien Hong / Thiagarajan, Nishanth / Tan, Swee Yaw / Amanullah, Mohammed Rizwan / Lim, Soo Teik / Aziz, Zameer Abdul / Govindasamy, Sivaraj / Chao, Victor Tar Toong / Ewe, See Hooi / Ho, Kay Woon

    Annals of the Academy of Medicine, Singapore

    2022  Volume 51, Issue 10, Page(s) 605–618

    Abstract: Introduction: Data on patients with small aortic annuli (SAA) undergoing transcatheter aortic valve implantation (TAVI) are limited. We aim to describe the impact of aortic annular size, particularly SAA and TAVI valve type on valve haemodynamics, ... ...

    Abstract Introduction: Data on patients with small aortic annuli (SAA) undergoing transcatheter aortic valve implantation (TAVI) are limited. We aim to describe the impact of aortic annular size, particularly SAA and TAVI valve type on valve haemodynamics, durability and clinical outcomes.
    Method: All patients in National Heart Centre Singapore who underwent transfemoral TAVI for severe symptomatic native aortic stenosis from July 2012 to December 2019 were included. Outcome measures include valve haemodynamics, prosthesis-patient mismatch (PPM), structural valve degeneration (SVD) and mortality.
    Results: A total of 244 patients were included. The mean Society of Thoracic Surgeons score was 6.22±6.08, with 52.5% patients with small aortic annulus (<23mm), 33.2% patients with medium aortic annulus (23-26mm) and 14.3% patients with large aortic annulus (>26mm). There were more patients with self-expanding valve (SEV) (65.2%) versus balloon-expandable valve (BEV) (34.8%). There were no significant differences in indexed aortic valve area (iAVA), mean pressure gradient (MPG), PPM, SVD or mortality across all aortic annular sizes. However, specific to the SAA group, patients with SEV had larger iAVA (SEV 1.19±0.35cm2/m2 vs BEV 0.88±0.15cm2/m2,
    Conclusion: Valve haemodynamics and durability were similar across the different aortic annular sizes. In the SAA group, SEV had better haemodynamics than BEV at 1 year, but no differences in PPM or mortality. There were no significant differences in mortality between aortic annular sizes, TAVI valve types or PPM.
    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement ; Heart Valve Prosthesis ; Aortic Valve Stenosis/surgery ; Aortic Valve/surgery ; Prosthesis Design ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Treatment Outcome ; Hemodynamics
    Language English
    Publishing date 2022-08-08
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2022167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2420: Show issues Location:
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