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  1. Article ; Online: Longitudinal Aging Study Amsterdam COVID-19 exposure index: a cross-sectional analysis of the impact of the pandemic on daily functioning of older adults.

    Hoogendijk, Emiel O / Schuster, Noah A / van Tilburg, Theo G / Schaap, Laura A / Suanet, Bianca / De Breij, Sascha / Kok, Almar Al / Van Schoor, Natasja M / Timmermans, Erik J / de Jongh, Renate T / Visser, Marjolein / Huisman, Martijn

    BMJ open

    2022  Volume 12, Issue 11, Page(s) e061745

    Abstract: Objectives: The aim of this study was to develop an index to measure older adults' exposure to the COVID-19 pandemic and to study its association with various domains of functioning.: Design: Cross-sectional study.: Setting: The Longitudinal Aging ...

    Abstract Objectives: The aim of this study was to develop an index to measure older adults' exposure to the COVID-19 pandemic and to study its association with various domains of functioning.
    Design: Cross-sectional study.
    Setting: The Longitudinal Aging Study Amsterdam (LASA), a cohort study in the Netherlands.
    Participants: Community-dwelling older adults aged 62-102 years (n=1089) who participated in the LASA COVID-19 study (June-September 2020), just after the first wave of the pandemic.
    Primary outcome measures: A 35-item COVID-19 exposure index with a score ranging between 0 and 1 was developed, including items that assess the extent to which the COVID-19 situation affected daily lives of older adults. Descriptive characteristics of the index were studied, stratified by several sociodemographic factors. Logistic regression analyses were performed to study associations between the exposure index and several indicators of functioning (functional limitations, anxiety, depression and loneliness).
    Results: The mean COVID-19 exposure index score was 0.20 (SD 0.10). Scores were relatively high among women and in the southern region of the Netherlands. In models adjusted for sociodemographic factors and prepandemic functioning (2018-2019), those with scores in the highest tertile of the exposure index were more likely to report functional limitations (OR: 2.24; 95% CI: 1.48 to 3.38), anxiety symptoms (OR: 3.14; 95% CI: 1.82 to 5.44), depressive symptoms (OR: 2.49; 95% CI: 1.55 to 4.00) and loneliness (OR: 2.97; 95% CI: 2.08 to 4.26) than those in the lowest tertile.
    Conclusions: Among older adults in the Netherlands, higher exposure to the COVID-19 pandemic was associated with worse functioning in the physical, mental and social domain. The newly developed exposure index may be used to identify persons for whom targeted interventions are needed to maintain or improve functioning during the pandemic or postpandemic.
    MeSH term(s) Female ; Humans ; Aged ; Pandemics ; COVID-19/epidemiology ; Cross-Sectional Studies ; Cohort Studies ; Aging ; Depression/diagnosis
    Chemical Substances lipid-associated sialic acid
    Language English
    Publishing date 2022-11-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-061745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Longitudinal Aging Study Amsterdam COVID-19 exposure index: a cross-sectional analysis of the impact of the pandemic on daily functioning of older adults

    Hoogendijk, Emiel O / Schuster, Noah A / van Tilburg, Theo G / Schaap, Laura A / Suanet, Bianca / de Breij, Sascha / Kok, Almar AL / van Schoor, Natasja M / Timmermans, Erik J / de Jongh, Renate T / Visser, Marjolein / Huisman, Martijn

    medRxiv

    Abstract: Objectives: The aim of this study was to develop an index to measure older adults` exposure to the COVID-19 pandemic, and to study its association with various domains of functioning. Design: Cross-sectional study. Setting: The Longitudinal Aging Study ... ...

    Abstract Objectives: The aim of this study was to develop an index to measure older adults` exposure to the COVID-19 pandemic, and to study its association with various domains of functioning. Design: Cross-sectional study. Setting: The Longitudinal Aging Study Amsterdam (LASA), a cohort study in the Netherlands. Participants: Community dwelling older adults aged 62-102 years (n=1089) who participated in the LASA COVID-19 study (June-September 2020), just after the first wave of the pandemic. Primary outcome measures: A 35-item COVID-19 exposure index with a score ranging between 0 and 1 was developed, including items that assess the extent to which the COVID-19 situation affected daily lives of older adults. Descriptive characteristics of the index were studied, stratified by several socio-demographic factors. Logistic regression analyses were performed to study associations between the exposure index and several indicators of functioning (functional limitations, anxiety, depression, and loneliness). Results: The mean COVID-19 exposure index score was 0.20 (SD 0.10). Scores were relatively high among women and in the southern region of the Netherlands. In models adjusted for socio-demographic factors and pre-pandemic functioning (2018-2019), those with scores in the highest tertile of the exposure index were more likely to report functional limitations (OR: 2.23; 95% CI: 1.48 to 3.38), anxiety symptoms (OR: 3.87; 95% CI: 2.27 to 6.61), depressive symptoms (OR: 2.45; 95% CI: 1.53 to 3.93) and loneliness (OR: 2.97; 95% CI: 2.08-4.26) than those in the lowest tertile. Conclusions: Among older adults in the Netherlands, those with higher scores on a COVID-19 exposure index reported worse functioning in the physical, mental and social domain. The index may be used to identify persons for whom targeted interventions are needed to maintain or improve functioning during the pandemic or post-pandemic.
    Keywords covid19
    Language English
    Publishing date 2022-02-03
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2022.02.02.22270309
    Database COVID19

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