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  1. Article ; Online: Restenosis After Carotid Artery Stenting.

    Armstrong, Ehrin J / Kokkinidis, Damianos G

    Cardiovascular revascularization medicine : including molecular interventions

    2021  Volume 24, Page(s) 70–71

    MeSH term(s) Carotid Arteries ; Constriction, Pathologic ; Endarterectomy, Carotid ; Humans ; Stents
    Language English
    Publishing date 2021-01-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2021.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: RNA Interference-based Therapies for the Reduction of Cardiovascular Risk.

    Nazarenko, Natalia / Seo, Jiyoung / Nagraj, Sanjana / Palaiodimos, Leonidas / Kokkinidis, Damianos G

    Current molecular pharmacology

    2024  

    Abstract: Globally, there remains an unwavering increase in the incidence of cvd - from 271 million in 1990 to 523 million in 2019. Among the several modifiable and non-modifiable risk factors of heart disease, dyslipidemia is an important and prevalent risk ... ...

    Abstract Globally, there remains an unwavering increase in the incidence of cvd - from 271 million in 1990 to 523 million in 2019. Among the several modifiable and non-modifiable risk factors of heart disease, dyslipidemia is an important and prevalent risk factor mediated by both genetics and lifestyle factors. Hence, lowering lipid levels, specifically, ldl-c levels (low-density lipoprotein cholesterol), is a key strategy in decreasing the risk of cardiovascular disease. A reduction of 20 mg/dl in ldl-c levels has been found to prevent 2-3 cases of coronary artery disease (cad) for every 1000 individuals. Studies have also found reductions in ldl-c levels to be associated with a mortality benefit. However, ldl-c levels reduction may not eliminate the risk of significant cardiovascular events.
    Language English
    Publishing date 2024-02-29
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1874-4702
    ISSN (online) 1874-4702
    DOI 10.2174/0118761429264553231204115314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Contemporary Management of Deep Vein Thrombosis, Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension.

    Sagris, Marios / Kokkinidis, Damianos G / Bakoyiannis, Christos

    Current pharmaceutical design

    2022  Volume 28, Issue 7, Page(s) 511

    MeSH term(s) Humans ; Hypertension, Pulmonary/drug therapy ; Pulmonary Embolism/drug therapy ; Venous Thrombosis/drug therapy
    Language English
    Publishing date 2022-04-05
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/138161282807220221103233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Current developments in endovascular therapy of peripheral vascular disease.

    Kokkinidis, Damianos G / Armstrong, Ehrin J

    Journal of thoracic disease

    2020  Volume 12, Issue 4, Page(s) 1681–1694

    Abstract: More than 200 million people worldwide have peripheral artery disease (PAD) or its most severe manifestation, critical limb ischemia (CLI). While endovascular treatment has become first line therapy in most cases, a number of challenges remain for ... ...

    Abstract More than 200 million people worldwide have peripheral artery disease (PAD) or its most severe manifestation, critical limb ischemia (CLI). While endovascular treatment has become first line therapy in most cases, a number of challenges remain for optimal treatment of femoropopliteal (FP) or infrapopliteal (IP) disease, especially when these lesions are severely calcified, chronic total occlusions (CTOs) or in-stent restenosis (ISR). Continued evolution of technologies has significantly improved the outcomes for endovascular treatment. A number of new devices are in the pipeline right now, including new paclitaxel eluting stents and balloons, intravascular lithotripsy to treat severely calcified lesions, adventitial delivery of anti-restenotic agents to limit restenosis rates, and percutaneous femoro-popliteal bypass.
    Language English
    Publishing date 2020-08-09
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2019.12.130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unilateral Femoral Access for Transfemoral Approach in Transcatheter Aortic Valve Replacement: The Happy Medium?

    Armstrong, Ehrin J / Kokkinidis, Damianos G

    Cardiovascular revascularization medicine : including molecular interventions

    2020  Volume 21, Issue 4, Page(s) 486–488

    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Heart Valve Prosthesis ; Humans ; Transcatheter Aortic Valve Replacement
    Language English
    Publishing date 2020-06-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2020.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vascular Closure Devices for Large-Bore Mechanical Circulatory Support Devices: Becoming MANT(d)Atory?

    Armstrong, Ehrin J / Kokkinidis, Damianos G

    Cardiovascular revascularization medicine : including molecular interventions

    2020  Volume 21, Issue 7, Page(s) 879–881

    MeSH term(s) Catheterization, Peripheral ; Femoral Artery ; Humans ; Vascular Closure Devices
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2020.04.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: EDITORIAL: Eximo Medical's B-Laser for Infrainguinal Peripheral Artery Disease: The New Kid on the Block for Lesion Preparation in Complex Peripheral Interventions?

    Armstrong, Ehrin J / Kokkinidis, Damianos G

    Cardiovascular revascularization medicine : including molecular interventions

    2020  Volume 21, Issue 1, Page(s) 93–95

    MeSH term(s) Atherectomy ; Humans ; Peripheral Arterial Disease
    Language English
    Publishing date 2020-02-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2019.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hypertension Management in Peripheral Artery Disease: A Mini Review.

    Kharawala, Amrin / Nagraj, Sanjana / Pargaonkar, Sumant / Seo, Jiyoung / Kokkinidis, Damianos G / Altin, S Elissa

    Current hypertension reviews

    2023  

    Abstract: Lower extremity peripheral artery disease (PAD) affects over 230 million adults globally, with hypertension being one of the major risk factors for the development of PAD. Despite the high prevalence, patients with hypertension who have concomitant PAD ... ...

    Abstract Lower extremity peripheral artery disease (PAD) affects over 230 million adults globally, with hypertension being one of the major risk factors for the development of PAD. Despite the high prevalence, patients with hypertension who have concomitant PAD are less likely to receive adequate therapy. Through this review, we present the current evidence underlying hypertension management in PAD, guideline-directed therapies, and areas pending further investigation. Multiple studies have shown that both high and relatively lower blood pressure levels are associated with worse health outcomes, including increased morbidity and mortality. Hence, guideline-directed recommendation involves cautious management of hypertensive patients with PAD while ensuring hypotension does not occur. Although any antihypertensive medication can be used to treat these patients, the 2017 American Heart Association/American College of Cardiology (AHA/ACC), 2017 European Society of Cardiology (ESC), and 2022 Canadian guidelines favor the use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) as the initial choice. Importantly, data on blood pressure targets and treatment of hypertension in PAD are limited and largely stem from sub-group studies and post-hoc analysis. Large randomized trials in patients with PAD are required in the future to delineate hypertension management in this complex patient population.
    Language English
    Publishing date 2023-12-11
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1875-6506
    ISSN (online) 1875-6506
    DOI 10.2174/0115734021267004231122061712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Venous Thromboembolism in Pregnancy: Challenges and Solutions.

    Varrias, Dimitrios / Spanos, Michail / Kokkinidis, Damianos G / Zoumpourlis, Panagiotis / Kalaitzopoulos, Dimitrios Rafail

    Vascular health and risk management

    2023  Volume 19, Page(s) 469–484

    Abstract: Venous thromboembolism (VTE) is a serious medical condition that can lead to severe morbidity and mortality, making it a significant public health concern. VTE is a multifactorial condition that results from the interaction of genetic, acquired, and ... ...

    Abstract Venous thromboembolism (VTE) is a serious medical condition that can lead to severe morbidity and mortality, making it a significant public health concern. VTE is a multifactorial condition that results from the interaction of genetic, acquired, and environmental factors. Physiological changes during pregnancy increase the risk of VTE as they express Virchow's triad (increased coagulation factors, decreased fibrinolysis, trauma, and venous stasis). Moreover, pregnancy-related risk factors, such as advanced maternal age, obesity, multiple gestations, and cesarean delivery, further increase the risk of VTE. Managing VTE in pregnancy is challenging due to the complexity of balancing the risks and benefits of anticoagulant therapy for both the mother and the fetus. A multidisciplinary approach involving obstetricians, hematologists, and neonatologists, is necessary to ensure optimal outcomes for both the mother and baby. This review aims to discuss the current challenges associated with VTE in pregnancy and identify potential solutions for improving outcomes for pregnant women at risk for VTE.
    MeSH term(s) Pregnancy ; Female ; Humans ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/epidemiology ; Risk Factors ; Anticoagulants/adverse effects
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-07-20
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2186568-1
    ISSN 1178-2048 ; 1176-6344
    ISSN (online) 1178-2048
    ISSN 1176-6344
    DOI 10.2147/VHRM.S404537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Inflammation, anti-inflammatory agents, and the role of colchicine in carotid artery stenosis.

    Chlorogiannis, David-Dimitris / Pargaonkar, Sumant / Papanagiotou, Panagiotis / Bakogiannis, Nikolaos C / Bakoyiannis, Christos / Kokkinidis, Damianos G

    VASA. Zeitschrift fur Gefasskrankheiten

    2023  Volume 53, Issue 1, Page(s) 4–12

    Abstract: Cardiovascular disease is a major cause of morbidity and mortality worldwide. In the last few years, the role of inflammation and inflammatory modulatory medications is investigated for the optimal treatment of coronary artery disease. It can be ... ...

    Abstract Cardiovascular disease is a major cause of morbidity and mortality worldwide. In the last few years, the role of inflammation and inflammatory modulatory medications is investigated for the optimal treatment of coronary artery disease. It can be hypothesized that since inflammation is also involved in carotid artery stenosis development and progression, the same class of medication could be useful. Our objective with this review is to present the available evidence, published studies and promising ongoing trials on the role of anti-inflammatory medications - with a special emphasis on the most commonly used drug of this class: colchicine - in patients with carotid artery stenosis.
    MeSH term(s) Humans ; Colchicine/adverse effects ; Carotid Stenosis/complications ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/drug therapy ; Anti-Inflammatory Agents/adverse effects ; Inflammation/drug therapy ; Coronary Artery Disease
    Chemical Substances Colchicine (SML2Y3J35T) ; Anti-Inflammatory Agents
    Language English
    Publishing date 2023-12-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 120977-2
    ISSN 1664-2872 ; 0301-1526
    ISSN (online) 1664-2872
    ISSN 0301-1526
    DOI 10.1024/0301-1526/a001104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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