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  1. Article: Calcium Hydroxylapatite (CaHA) and Aesthetic Outcomes: A Systematic Review of Controlled Clinical Trials.

    Amiri, Mojgan / Meçani, Renald / Llanaj, Erand / Niehot, Christa D / Phillips, Terri L / Goldie, Katherine / Kolb, Janina / Muka, Taulant / Daughtry, Hua

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Skin regeneration-related mechanisms of Calcium Hydroxylapatite (CaHA): a systematic review.

    Amiri, Mojgan / Meçani, Renald / Niehot, Christa D / Phillips, Terri / Kolb, Janina / Daughtry, Hua / Muka, Taulant

    Frontiers in medicine

    2023  Volume 10, Page(s) 1195934

    Abstract: Introduction: Calcium Hydroxylapatite (CaHA) is a common dermal filler used in aesthetic medicine for volumizing and contouring. Understanding mechanisms of actions of CaHA can help improve our understanding of its clinical applications.: Methods: We ...

    Abstract Introduction: Calcium Hydroxylapatite (CaHA) is a common dermal filler used in aesthetic medicine for volumizing and contouring. Understanding mechanisms of actions of CaHA can help improve our understanding of its clinical applications.
    Methods: We performed a systematic review to summarize the skin-regeneration related mechanisms of CaHA. Five bibliographic databases were searched for English-language publications that evaluated CaHA in skin regeneration outcomes including neocollagenesis, cell proliferation and growth factors, angiogenesis, vascular dynamic and inflammatory markers, among others. Methodological rigor of included studies was assessed.
    Results: Of 2,935 identified citations, 12 studies were included for final analysis. Collagen production was reported by nine studies, cell proliferation by four, elastic fibers and/or elastin by four, and three studies on angiogenesis, while limited studies were available on the other outcomes. Six were clinical/observational studies. Only seven studies had a control group. Overall, studies showed CaHA resulted in increased cell proliferation, increased collagen production and angiogenesis, as well as in higher elastic fiber and elastin formation. Limited and inconclusive evidence was available on the other mechanisms. The majority of the studies had methodological limitations.
    Discussion: Current evidence is limited but indicates several mechanisms through which CaHA could lead to skin regeneration, volume enhancement, and contouring.
    Systematic review registration: https://doi.org/10.17605/OSF.IO/WY49V.
    Language English
    Publishing date 2023-06-02
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1195934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; Thesis: Immunphänotypisierung von Patienten im Rahmen von Operationen an der Herz-Lungen-Maschine hinsichtlich der Entwicklung eines systemisch inflammatorischen Response-Syndroms

    Kolb, Janina [Verfasser] / Bode, Christian [Akademischer Betreuer] / Kalff, Jörg C. [Gutachter]

    2022  

    Author's details Janina Louisa Kolb ; Gutachter: Jörg C. Kalff ; Betreuer: Christian Bode
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek Bonn
    Publishing place Bonn
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Article ; Online: Genetic characterization of German Mycobacterium avium strains isolated from different hosts and specimens by multilocus sequence typing.

    Kolb, Janina / Hillemann, Doris / Möbius, Petra / Reetz, Jochen / Lahiri, Annesha / Lewin, Astrid / Rüsch-Gerdes, Sabine / Richter, Elvira

    International journal of medical microbiology : IJMM

    2014  Volume 304, Issue 8, Page(s) 941–948

    Abstract: Infections caused by Mycobacterium avium and its subspecies are reported as emerging disease in many countries worldwide. In our study we applied the multilocus sequence typing technology to 98 German M. avium strains originating from different hosts and ...

    Abstract Infections caused by Mycobacterium avium and its subspecies are reported as emerging disease in many countries worldwide. In our study we applied the multilocus sequence typing technology to 98 German M. avium strains originating from different hosts and specimens to examine the degree of the genetic diversity. By MLST, 80% of strains were identified as subspecies 'M. avium hominissuis', and 20% as subspecies M. avium avium/M. avium silvaticum. Distinctly different MLST profiles were identified for both subspecies. Based on the analysis of 4 and 5 loci, 87 and 106 SNPs and 1 codon deletion could be detected, respectively, resulting in 40 different strain profiles. Twelve out of these have recently been described for strains coming from different countries, yet in our study, additional new strain profiles (n=28) were found. The high degree of diversity within 'M. avium subsp. hominissuis' as well as the relatedness of human, porcine and environmental strains could be confirmed by IS1245 RFLP fingerprinting. The detection of ISMav6 and hsp65 code 15 in one adult patient strain being positive for IS901, but displaying 'M. avium subsp. hominissuis' MLST profile revealed that PCR for detection of IS901 is not a definitive proof of M. avium subsp. avium/M. avium subsp. silvaticum.
    MeSH term(s) Adult ; Animals ; Child ; Genetic Variation ; Genotype ; Humans ; Molecular Epidemiology ; Molecular Sequence Data ; Multilocus Sequence Typing ; Mycobacterium avium/classification ; Mycobacterium avium/genetics ; Mycobacterium avium/isolation & purification ; Sequence Analysis, DNA ; Tuberculosis/microbiology ; Tuberculosis/veterinary
    Language English
    Publishing date 2014-11
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2006518-8
    ISSN 1618-0607 ; 1438-4221
    ISSN (online) 1618-0607
    ISSN 1438-4221
    DOI 10.1016/j.ijmm.2014.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5333: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Amplified canonical transforming growth factor-β signalling

    Sibinska, Zaneta / Tian, Xia / Korfei, Martina / Kojonazarov, Baktybek / Kolb, Janina Susanne / Klepetko, Walter / Kosanovic, Djuro / Wygrecka, Malgorzata / Ghofrani, Hossein Ardeschir / Weissmann, Norbert / Grimminger, Friedrich / Seeger, Werner / Guenther, Andreas / Schermuly, Ralph T

    The European respiratory journal

    2017  Volume 49, Issue 2

    Abstract: Interstitial lung fibroblast activation coupled with extracellular matrix production is a pathological signature of idiopathic pulmonary fibrosis (IPF), and is governed by transforming growth factor (TGF)-β/Smad signalling. We sought to define the role ... ...

    Abstract Interstitial lung fibroblast activation coupled with extracellular matrix production is a pathological signature of idiopathic pulmonary fibrosis (IPF), and is governed by transforming growth factor (TGF)-β/Smad signalling. We sought to define the role of heat shock protein (HSP)90 in profibrotic responses in IPF and to determine the therapeutic effects of HSP90 inhibition in a murine model of pulmonary fibrosis.We investigated the effects of HSP90 inhibition
    Language English
    Publishing date 2017-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01941-2015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2322: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

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