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Article ; Online: Sleep Quality and Evening Salivary Cortisol Levels in Association with the Psychological Resources of Parents of Children with Developmental Disorders and Type 1 Diabetes.

Ljubičić, Marija / Šare, Sonja / Kolčić, Ivana

Journal of autism and developmental disorders

2024

Abstract: Background: Sleep deprivation can decrease parental well-being and degrade mental and physical health in parents of children with chronic illness. The aim of this study was to explore the associations of sleep quality, psychological stress perception, ... ...

Abstract	Background: Sleep deprivation can decrease parental well-being and degrade mental and physical health in parents of children with chronic illness. The aim of this study was to explore the associations of sleep quality, psychological stress perception, and evening salivary cortisol concentration with self-esteem, optimism and happiness in parents of children with type 1 diabetes and developmental disorders compared to parents of healthy, typically developing children. Methods: We studied 196 parents of children with chronic conditions, including autistic spectrum disorder (N = 33), cerebral palsy (N = 18), Down syndrome (N = 33), and diabetes mellitus type 1 (N = 40) and parents of healthy children (N = 72). We evaluated parental sleep quality, evening salivary cortisol levels, self-esteem, optimism and happiness. Multiple linear regression models were used to assess associations between variables. Results: Compared with those of the control group, the parents of children with autistic spectrum disorders had higher evening cortisol concentrations (β = 0.17; p = 0.038) and lower perceptions of happiness (β=-0.17; p = 0.017), while parents of children with type 1 diabetes had disrupted sleep quality (β = 0.25; p = 0.003). Optimism was negatively associated with the evening cortisol concentration (β=-0.18; p = 0.023) and sleep quality index (β=-0.20; p = 0.012). Conclusions: Public health programs aimed at lifestyle habit improvement, respite care, and relaxation for parents of children with chronic conditions would be useful for improving parental sleep quality, self-esteem, optimism and happiness.
Language	English
Publishing date	2024-02-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	391999-7
ISSN	1573-3432 ; 0162-3257
ISSN (online)	1573-3432
ISSN	0162-3257
DOI	10.1007/s10803-024-06269-7
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Article ; Online: Differences between Health and Non-Health Science Students in Lifestyle Habits, Perceived Stress and Psychological Well-Being: A Cross-Sectional Study.

Marendić, Mario / Aranza, Diana / Aranza, Ivan / Vladislavić, Silvija / Kolčić, Ivana

Nutrients

2024 Volume 16, Issue 5

Abstract: The aim of this study was to investigate lifestyle habits in health and non-health science students from the University of Split, Croatia, and to evaluate their association with perceived stress and psychological well-being. We surveyed 783 students ... ...

Abstract	The aim of this study was to investigate lifestyle habits in health and non-health science students from the University of Split, Croatia, and to evaluate their association with perceived stress and psychological well-being. We surveyed 783 students during February-March 2021. Hierarchical multiple regression analysis was used in the analysis. Health science students spent less time using screens, were sitting less, slept less, but also showed better compliance with the Mediterranean diet compared to non-health science students (10.6% vs. 5.9%). There were no differences in stress and well-being perception between the two study groups. Female gender, lack of sleep, less daily sitting time, anxiety, and lower optimism were associated with higher stress in non-health science students, while anxiousness and more sitting were found to be significant among health students. Well-being among health science students was positively associated with BMI, having had COVID-19, being refreshed after waking up during working days, Mediterranean diet adherence, health perception, optimism, and quality of life, and negatively with TV time and anxiousness. Shorter sleep duration on non-working days, feeling refreshed after waking up on non-working days, higher quality of life and optimism, and lower anxiousness were associated with higher well-being among non-health students. Identifying unhealthy lifestyle habits in students is essential for implementing targeted interventions to better their health outcomes.
MeSH term(s)	Humans ; Female ; Cross-Sectional Studies ; Quality of Life ; Psychological Well-Being ; Life Style ; Students/psychology ; Habits ; Stress, Psychological ; Universities
Language	English
Publishing date	2024-02-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16050620
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Article: Family and Individual Quality of Life in Parents of Children with Developmental Disorders and Diabetes Type 1.

Ljubičić, Marija / Delin, Sanja / Kolčić, Ivana

Journal of clinical medicine

2022 Volume 11, Issue 10

Abstract: Background: This cross-sectional study assessed both family and individual quality of life (QOL), and their association with self-esteem, optimism, chronic psychological stress, anxiety, and depression in parents of children with chronic conditions.: ... ...

Abstract	Background: This cross-sectional study assessed both family and individual quality of life (QOL), and their association with self-esteem, optimism, chronic psychological stress, anxiety, and depression in parents of children with chronic conditions. Methods: Parents of children with Down syndrome (DS), autistic spectrum disorder (ASD), cerebral palsy (CP), diabetes mellitus type 1 (DMT1), and parents of children without chronic diseases with typical development (TD) were included. Multivariate linear regression analysis was used to assess parental characteristics associated with the domains of individual and family QOL. Results: Compared to the parents of TD children, parents of children with ASD and DS were more likely to report reduced family QOL in all domains, while parents of children with DMT1 had lower parental perception. Self-esteem was positively associated with all domains of individual QOL, while optimism was associated with the overall individual QOL perception and health. Higher stress perception was negatively associated with most of the domains of individual and family QOL. Conclusions: This study confirmed that parents of children with chronic conditions are more likely to have lower perception of both individual and family QOL, which were associated with self-esteem, chronic stress, anxiety, and depression. Interventions should focus not only on the child with a chronic condition but on parents too.
Language	English
Publishing date	2022-05-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11102861
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Article ; Online: Longitudinal Study on the Effect of Onboard Service on Seafarers' Health Statuses.

Russo, Andrea / Mulić, Rosanda / Kolčić, Ivana / Maleš, Matko / Jerončić Tomić, Iris / Pezelj, Luka

International journal of environmental research and public health

2023 Volume 20, Issue 5

Abstract: Seafaring is considered one of the most stressful professions. Stressors in seafaring lead to typical symptoms of stress, such as insomnia, loss of concentration, anxiety, lower tolerance of frustration, changes in eating habits, psychosomatic symptoms ... ...

Abstract	Seafaring is considered one of the most stressful professions. Stressors in seafaring lead to typical symptoms of stress, such as insomnia, loss of concentration, anxiety, lower tolerance of frustration, changes in eating habits, psychosomatic symptoms and diseases, and overall reduced productivity, with the possibility of burnout and chronic responsibility syndrome. It has been previously determined that seafarers belong to high-risk occupations in terms of developing metabolic syndrome, and according to their BMIs, almost 50% of all seafarers belong to the overweight and obesity categories. This is the first longitudinal study conducted with the aim of using the BIA method to determine the anthropometrical changes that occur during several weeks of continuous onboard service. This study included an observed group consisting of 63 professional seafarers with 8 to 12 weeks of continuous onboard service and a control group of 36 respondents from unrelated occupations. It was determined that Croatian seafarers fit into the current world trends regarding overweight and obesity among the seafaring population, with the following percentages in the BMI categories: underweight, 0%; normal weight, 42.86%; overweight, 39.68%; and obesity, 17.46%. It was established that the anthropometric statuses of the seafarers significantly changed during several weeks of continuous onboard service. Seafarers who served on board for 11 weeks lost 0.41 kg of muscle mass, whereas their total fat mass increased by 1.93 kg. Changes in anthropometric parameters could indicate deterioration of seafarers' health statuses.
MeSH term(s)	Humans ; Ships ; Overweight ; Longitudinal Studies ; Obesity/epidemiology ; Metabolic Syndrome/epidemiology ; Naval Medicine
Language	English
Publishing date	2023-03-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20054497
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Article: Double burden of malnutrition: A silent driver of double burden of disease in low- and middle-income countries.

Kolčić, Ivana

Journal of global health

2013 Volume 2, Issue 2, Page(s) 20303

Language	English
Publishing date	2013-01-03
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	2741629-X
ISSN	2047-2986 ; 2047-2978
ISSN (online)	2047-2986
ISSN	2047-2978
DOI	10.7189/jogh.02.020303
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Article ; Online: Achieving millennium development goals 4 and 5: do every mother and child really count?

Kolčić, Ivana

Croatian medical journal

2013 Volume 54, Issue 2, Page(s) 107–109

MeSH term(s)	Child ; Developing Countries ; Economic Development ; Female ; Goals ; Health Promotion ; Healthy People Programs ; Humans ; Male ; Primary Health Care
Language	English
Publishing date	2013-04-29
Publishing country	Croatia
Document type	Editorial
ZDB-ID	1157623-6
ISSN	1332-8166 ; 0353-9504
ISSN (online)	1332-8166
ISSN	0353-9504
DOI	10.3325/cmj.2013.54.107
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Zs.A 187: Show issues

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Article ; Online: Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk.

Gelemanović, Andrea / Ćatipović Ardalić, Tatjana / Pribisalić, Ajka / Hayward, Caroline / Kolčić, Ivana / Polašek, Ozren

International journal of molecular sciences

2023 Volume 24, Issue 8

Abstract: Infectious diseases still threaten global human health, and host genetic factors have been indicated as determining risk factors for observed variations in disease susceptibility, severity, and outcome. We performed a genome-wide meta-analysis on 4624 ... ...

Abstract	Infectious diseases still threaten global human health, and host genetic factors have been indicated as determining risk factors for observed variations in disease susceptibility, severity, and outcome. We performed a genome-wide meta-analysis on 4624 subjects from the 10,001 Dalmatians cohort, with 14 infection-related traits. Despite a rather small number of cases in some instances, we detected 29 infection-related genetic associations, mostly belonging to rare variants. Notably, the list included the genes CD28, INPP5D, ITPKB, MACROD2, and RSF1, all of which have known roles in the immune response. Expanding our knowledge on rare variants could contribute to the development of genetic panels that could assist in predicting an individual's life-long susceptibility to major infectious diseases. In addition, longitudinal biobanks are an interesting source of information for identifying the host genetic variants involved in infectious disease susceptibility and severity. Since infectious diseases continue to act as a selective pressure on our genomes, there is a constant need for a large consortium of biobanks with access to genetic and environmental data to further elucidate the complex mechanisms behind host-pathogen interactions and infectious disease susceptibility.
MeSH term(s)	Humans ; Genetic Predisposition to Disease ; Phenotype ; Risk Factors ; Genome-Wide Association Study ; Communicable Diseases/genetics ; Nuclear Proteins/genetics ; Trans-Activators/genetics
Chemical Substances	RSF1 protein, human ; Nuclear Proteins ; Trans-Activators
Language	English
Publishing date	2023-04-10
Publishing country	Switzerland
Document type	Meta-Analysis ; Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24087006
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Article ; Online: Variability of human Alpha-1-acid glycoprotein N-glycome in a Caucasian population.

Vučković, Frano / Novokmet, Mislav / Šoić, Dinko / Štambuk, Jerko / Kolčić, Ivana / Polašek, Ozren / Lauc, Gordan / Gornik, Olga / Keser, Toma

Glycobiology

2024 Volume 34, Issue 6

Abstract: Aim: Alpha-1-acid glycoprotein (AGP) is a highly glycosylated protein in human plasma and one of the most abundant acute phase proteins in humans. Glycosylation plays a crucial role in its biological functions, and alterations in AGP N-glycome have been ...

Abstract	Aim: Alpha-1-acid glycoprotein (AGP) is a highly glycosylated protein in human plasma and one of the most abundant acute phase proteins in humans. Glycosylation plays a crucial role in its biological functions, and alterations in AGP N-glycome have been associated with various diseases and inflammatory conditions. However, large-scale studies of AGP N-glycosylation in the general population are lacking. Methods: Using recently developed high-throughput glycoproteomic workflow for site-specific AGP N-glycosylation analysis, 803 individuals from the Croatian island of Korcula were analyzed and their AGP N-glycome data associated with biochemical and physiological traits, as well as different environmental factors. Results: After regression analysis, we found that AGP N-glycosylation is strongly associated with sex, somewhat less with age, along with multiple biochemical and physiological traits (e.g. BMI, triglycerides, uric acid, glucose, smoking status, fibrinogen). Conclusion: For the first time we have extensively explored the inter-individual variability of AGP N-glycome in a general human population, demonstrating its changes with sex, age, biochemical, and physiological status of individuals, providing the baseline for future population and clinical studies.
MeSH term(s)	Humans ; Orosomucoid/metabolism ; Male ; Female ; Glycosylation ; Middle Aged ; White People ; Adult ; Aged ; Croatia
Chemical Substances	Orosomucoid
Language	English
Publishing date	2024-04-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1067689-2
ISSN	1460-2423 ; 0959-6658
ISSN (online)	1460-2423
ISSN	0959-6658
DOI	10.1093/glycob/cwae031
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Zs.A 3150: Show issues

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Article ; Online: Awakening cortisol indicators, advanced glycation end products, stress perception, depression and anxiety in parents of children with chronic conditions.

Ljubičić, Marija / Baković, Lada / Ćoza, Martina / Pribisalić, Ajka / Kolčić, Ivana

Psychoneuroendocrinology

2020 Volume 117, Page(s) 104709

Abstract: This cross-sectional study aims to investigate awakening cortisol indicators and to explore their association with stress perception, advanced glycation end products (AGEs), depression and anxiety in parents of children with chronic conditions. We ... ...

Abstract	This cross-sectional study aims to investigate awakening cortisol indicators and to explore their association with stress perception, advanced glycation end products (AGEs), depression and anxiety in parents of children with chronic conditions. We included five parental groups according to children's diagnoses: Down syndrome (DS; N = 31), autistic spectrum disorder (ASD; N = 29), cerebral palsy (CP; N = 15), diabetes mellitus type 1 (DMT1; N = 38), and a control group of heathy children (CG; N = 33). Salivary cortisol and AGEs were measured, alongside with psychological indices. Partial correlation and multiple linear regression were used in the analysis to identify parental characteristics associated with total awakening cortisol output (area under the curve with respect to the ground, AUC
MeSH term(s)	Adult ; Anxiety/metabolism ; Anxiety/physiopathology ; Anxiety/psychology ; Child ; Chronic Disease ; Circadian Rhythm/physiology ; Cross-Sectional Studies ; Depression/metabolism ; Depression/physiopathology ; Depression/psychology ; Diabetes Mellitus, Type 1/nursing ; Disabled Children ; Female ; Glycation End Products, Advanced/metabolism ; Humans ; Hydrocortisone/metabolism ; Male ; Neurodevelopmental Disorders/nursing ; Parents/psychology ; Saliva ; Stress, Psychological/metabolism ; Stress, Psychological/physiopathology ; Stress, Psychological/psychology
Chemical Substances	Glycation End Products, Advanced ; Hydrocortisone (WI4X0X7BPJ)
Language	English
Publishing date	2020-05-19
Publishing country	England
Document type	Journal Article
ZDB-ID	197636-9
ISSN	1873-3360 ; 0306-4530
ISSN (online)	1873-3360
ISSN	0306-4530
DOI	10.1016/j.psyneuen.2020.104709
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Zs.A 1235: Show issues

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Article ; Online: Coronavirus epidemic in Croatia: case fatality decline during summer?

Kristić, Ivica / Pehlić, Marina / Pavlović, Mirjana / Kolarić, Branko / Kolčić, Ivana / Polašek, Ozren

Croatian medical journal

2021 Volume 61, Issue 6, Page(s) 501–507

Abstract: Aim: To describe the SARS-CoV-2 epidemic pattern in Croatia during February-September 2020 and compare the case fatality ratio (CFR) between spring and summer.: Methods: National data were used to calculate the weekly and monthly CFRs, stratified by ... ...

Abstract	Aim: To describe the SARS-CoV-2 epidemic pattern in Croatia during February-September 2020 and compare the case fatality ratio (CFR) between spring and summer. Methods: National data were used to calculate the weekly and monthly CFRs, stratified by three age groups: 0-64, 65-79, and 80+ years. We also calculated the standardized mortality ratios (SMR) to offset the differences in age composition. Results: The epidemic consisted of the initial wave, a trough in June, and two conjoined summer waves, yielding 17206 coronavirus disease 2019 cases and 290 deaths. While the number of confirmed cases nearly quadrupled during summer, case fatality estimates decreased; CFR in spring was 4.81 (95% confidence interval 3.91-5.71), compared with 1.24 (1.06-1.42) in summer. The SMR for summer was 0.45 (0.37-0.55), suggesting that the case fatality risk halved compared with spring. Cardiovascular comorbidity was an important risk factor for case fatality (SMR 2.63 [2.20-3.13] during spring and 1.28 [1.02-1.59] during summer). The risk of death in ventilated patients remained unchanged (SMR 0.98 [0.77-1.24]). Conclusions: The epidemic dynamics suggests summer decline in case fatality, except in ventilated patients. While the effect of comorbidity also decreased, cardiovascular comorbidity remained an important risk factor for death even during summer. A plethora of possible confounders and an ever-changing landscape of SARS-CoV-2 epidemic in Croatia require constant monitoring and evaluation, with an aim to prevent the uncontrolled spread of the virus and a disruption of health care functioning.
MeSH term(s)	Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/mortality ; Child ; Child, Preschool ; Comorbidity ; Croatia/epidemiology ; Epidemics ; Epidemiological Monitoring ; Female ; Hospitalization ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Risk Factors ; Seasons ; Young Adult
Language	English
Publishing date	2021-01-06
Publishing country	Croatia
Document type	Journal Article
ZDB-ID	1157623-6
ISSN	1332-8166 ; 0353-9504
ISSN (online)	1332-8166
ISSN	0353-9504
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