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Article ; Online: C-Reactive Protein Taken on Postoperative Day 3 Has No Role in Predicting Complications After Elective Colorectal Surgery: an Observational Study from the Randomized Multi-Center Prospective SOAP Trial.

Papp, G / Vereczkei, A / Kollár, D / Mersich, T / Bursics, A

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

2022 Volume 26, Issue 12, Page(s) 2595–2596

MeSH term(s)	Humans ; Colorectal Surgery ; C-Reactive Protein/metabolism ; Prospective Studies ; Elective Surgical Procedures/adverse effects ; Postoperative Period ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Colorectal Neoplasms/surgery ; Colorectal Neoplasms/complications
Chemical Substances	C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2022-07-19
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	2012365-6
ISSN	1873-4626 ; 1934-3213 ; 1091-255X
ISSN (online)	1873-4626 ; 1934-3213
ISSN	1091-255X
DOI	10.1007/s11605-022-05400-2
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Zs.A 5207: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Surgical Aspects of Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Oláh, A / Kollár, D

Chirurgia (Bucharest, Romania : 1990)

2015 Volume 110, Issue 5, Page(s) 413–417

Abstract: Intraductal papillary mucinous neoplasms (IPMN) play an important role mongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically ...

Abstract	Intraductal papillary mucinous neoplasms (IPMN) play an important role mongst exocrine tumours of the pancreas due to several causes. Although they count for only 1% of all the tumours, they represent some 20-30% of all cystic neoplasms, a histologically defined group that has gained a lot of attention lately. IPMNs of the main or the secondary (branch) pancreatic ducts have remarkably different rates of malignant transformation, prognosis and thus indication for surgery. Prognosis of a ductal carcinoma developing from IPMN does not differ from classic ductal adenocarcinoma, with a very poor (10%) 5-year survival rate. However, prognosis of IPMN can still be regarded favourable, because the above rate can be as high as 70% if the tumour is non-invasive. This fact leads to the importance of diagnosing and resecting IPMN before its malignant transformation into an invasive carcinoma.
MeSH term(s)	Adenocarcinoma, Mucinous/diagnosis ; Adenocarcinoma, Mucinous/mortality ; Adenocarcinoma, Mucinous/surgery ; Carcinoma, Pancreatic Ductal/diagnosis ; Carcinoma, Pancreatic Ductal/mortality ; Carcinoma, Pancreatic Ductal/surgery ; Carcinoma, Papillary/diagnosis ; Carcinoma, Papillary/mortality ; Carcinoma, Papillary/surgery ; Cell Transformation, Neoplastic ; Diagnosis, Differential ; Early Detection of Cancer ; Humans ; Hungary/epidemiology ; Incidence ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/surgery ; Risk Factors ; Survival Rate ; Treatment Outcome
Language	English
Publishing date	2015-09
Publishing country	Romania
Document type	Journal Article
ZDB-ID	419244-8
ISSN	1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
ISSN (online)	1842-368X
ISSN	1221-9118 ; 0009-4730 ; 0377-5003
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Zs.MO 620: Show issues

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Article ; Online: To Feed or Not to Feed - Nutritional Risk Assessment and Support in Elective Colorectal Surgery. A Prospective Study on the Effect of Screening.

Kollár, Dániel / Benedek-Tóth, Zoltán / Drozgyik, András / Molnár, Tamás F / Oláh, Attila

Nutrition and cancer

2022 Volume 74, Issue 10, Page(s) 3509–3517

Abstract: Colorectal cancer (CRC) is the third most common malignant tumor and resection remains the key element in its treatment. The correction of preoperative malnutrition reduces morbidity and mortality. Our study demonstrates a nutritional state mass ... ...

Abstract	Colorectal cancer (CRC) is the third most common malignant tumor and resection remains the key element in its treatment. The correction of preoperative malnutrition reduces morbidity and mortality. Our study demonstrates a nutritional state mass screening protocol to steer nutritional support. Two hundred fifty-nine patients with planned colorectal resection were prospectively enrolled. Preoperative telemedicinal assessment determined the risk of malnutrition using Nutritional Risk Screening 2002 (NRS 2002) score. Patients with a score ≥3 were offered optimized oral nutritional supplement. Three groups were investigated. Group I (NRS 2002 < 3,
MeSH term(s)	Colorectal Surgery ; Humans ; Length of Stay ; Malnutrition/etiology ; Mass Screening/methods ; Nutrition Assessment ; Nutritional Status ; Prospective Studies ; Risk Assessment
Language	English
Publishing date	2022-05-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	424433-3
ISSN	1532-7914 ; 0163-5581
ISSN (online)	1532-7914
ISSN	0163-5581
DOI	10.1080/01635581.2022.2077384
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Article: Primary healing of tuberculous otitis media on combined operative and streptomycin therapy.

KOLLAR, D

Acta oto-laryngologica

2002 Volume 42, Issue 4-5, Page(s) 399–403

MeSH term(s)	Disease ; Ear Diseases ; Ear, Middle ; Humans ; Otitis Media ; Streptomycin/therapeutic use ; Tuberculosis ; Wound Healing
Chemical Substances	Streptomycin (Y45QSO73OB)
Language	English
Publishing date	2002-11-26
Publishing country	England
Document type	Journal Article
ISSN	0001-6489
ISSN	0001-6489
DOI	10.3109/00016485209120367
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Article ; Online: Glasgow Prognostic Score: Another Global Positioning System to Assess Patients with Lung Cancer?

Molnar, Tamas F / Kollar, Daniel

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

2016 Volume 11, Issue 8, Page(s) 1194–1196

Language	English
Publishing date	2016-08
Publishing country	United States
Document type	Editorial
ZDB-ID	2432037-7
ISSN	1556-1380 ; 1556-0864
ISSN (online)	1556-1380
ISSN	1556-0864
DOI	10.1016/j.jtho.2016.06.009
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Zs.A 6664: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Complex oncologic therapy for loco-regionally advanced breast cancer associated with long-lasting SARS-CoV-2 PCR-positivity

Drozgyik, András / Kollár, Dániel / Knausz, Márta / Sipőcz, István / Molnár, F Tamás / Kullmann, Tamás

Orvosi hetilap

2021 Volume 162, Issue 16, Page(s) 611–614

Abstract: Összefoglaló. A COVID-19 mortalitását a súlyos társbetegségek, közöttük bizonyos daganatos betegségek is növelik. Immunszuppresszív hatásuk miatt felmerülhet a citotoxikus kezelések rizikónövelő hatása is. Ugyanakkor az onkológiai terápia megszakítása ... ...

Title translation	Tartós SARS-CoV-2-PCR-pozitivitáshoz társuló, lokoregionálisan előrehaladott emlődaganat komplex onkológiai kezelése.
Abstract	Összefoglaló. A COVID-19 mortalitását a súlyos társbetegségek, közöttük bizonyos daganatos betegségek is növelik. Immunszuppresszív hatásuk miatt felmerülhet a citotoxikus kezelések rizikónövelő hatása is. Ugyanakkor az onkológiai terápia megszakítása vagy halasztása, különösen az agresszívebb, kiterjedtebb és fiatalkorban jelentkező daganatok esetében ronthatja a kórjóslatot. Egy 39 éves nőbeteg esetét ismertetjük. A járvány során késlekedve felismert, lokoregionálisan kiterjedt emlődaganat miatt primer szisztémás kemoterápiában részesült. A kezelés 5. ciklusa során enyhe légúti tünetek kapcsán, az onkológiai ambulancián SARS-CoV-2-fertőzése igazolódott. Kemoterápiás kezelését felfüggesztettük. A diagnózistól számított 3. napon tünetmentessé vált, ám SARS-CoV-2-PCR-pozitivitása még a 43. napon is fennállt. A 19. napon hormongátló kezelést indítottunk. Az 51. napon mastectomia és axillaris block dissectio történt. A 82. napon a megszakított kemoterápiát a hormongátló kezelés leállítását követően G-CSF-profilaxis mellett újraindítottuk. A kezelés során fertőzéses szövődményt nem észleltünk. Kemoterápia és műtét SARS-CoV-2-fertőzött, tünetmentes daganatos betegnél szövődménymentesen végezhető elhúzódó virológiai pozitivitás esetén, felszabadító vizsgálat nélkül is. A daganatos betegek koronavírus-fertőzése esetén az onkológiai protokolltól történő eltérés egyénre szabott optimalizálásával és a multidiszciplináris team szorosabb együttműködésével az infektológiai és az onkológiai kockázat együttes alacsonyan tartása is megvalósítható. Orv Hetil. 2021; 162(16): 611-614. Summary. Mortality of COVID-19 is increased when certain co-morbidities, among others advanced malignancies are present. Deleterious effect of cytotoxic therapy, related to its immunosuppressive effect, may also be hypothesised. However, postponing or cancelling oncologic treatment, especially in younger patients with advanced and more aggressive tumors may worsen the prognosis. The case of a 39-year-old female patient is presented, who was diagnosed with loco-regionally advanced breast cancer during the pandemic. Primary systemic chemotherapy was started. The patient presented with acute respiratory tract symptoms during the fifth cycle and subsequently SARS-CoV-2 infection was diagnosed. Chemotherapy was cancelled. Symptoms resolved in three days after diagnosis. SARS-CoV-2 PCR remained positive up to day 43. Antihormonal therapy was introduced on day 19 and she underwent mastectomy with axillary lymph node dissection on day 51. Chemotherapy was reset postoperatively on day 82 with prophylactic G-CSF protection. No adverse event was observed throughout the treatment. Cytotoxic chemotherapy and surgery can be successfully delivered in breast cancer patients with prolonged asymptomatic SARS-CoV-2 PCR positivity, even without negative swab result. Individual optimisation of the therapy may require deviations from standard protocols. Closer multidisciplinary cooperation may contribute to the minimisation of both oncologic and infectious risks. Orv Hetil. 2021; 162(16): 611-614.
MeSH term(s)	Adult ; Breast Neoplasms/therapy ; COVID-19/complications ; COVID-19/diagnosis ; Female ; Humans ; Mastectomy ; Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Treatment Outcome
Language	Hungarian
Publishing date	2021-04-07
Publishing country	Hungary
Document type	Case Reports ; Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2021.32192
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Article ; Online: Perioperative nutritional state as a surgical risk in oncologic patients

Kollár, Dániel / Benedek-Tóth, Zoltán / Drozgyik, András / Molnár, F Tamás / Oláh, Attila

Orvosi hetilap

2021 Volume 162, Issue 13, Page(s) 504–513

Title translation	A perioperatív tápláltsági állapot mint kockázati tényező az onkológiai sebészetben.
MeSH term(s)	Female ; Humans ; Hungary ; Malnutrition/diagnosis ; Mass Screening/methods ; Neoplasms/surgery ; Perioperative Care ; Predictive Value of Tests ; Risk Factors
Language	Hungarian
Publishing date	2021-03-28
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2021.31987
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Article ; Online: Author response: Systemic versus oral and systemic antibiotic prophylaxis (SOAP) study in colorectal surgery: prospective randomized multicentre trial.

Papp, G / Saftics, G / Szabó, B E / Baracs, J / Vereczkei, A / Kollár, D / Oláh, A / Mészáros, P / Dubóczki, Z / Bursics, A

The British journal of surgery

2021 Volume 108, Issue 9, Page(s) e315

MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Colorectal Surgery ; Humans ; Prospective Studies ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/prevention & control
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-11-05
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	2985-3
ISSN	1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
ISSN (online)	1365-2168
ISSN	0263-1202 ; 0007-1323 ; 1355-7688
DOI	10.1093/bjs/znab190
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Article: Tompa pancreastrauma diagnózisa és kezelése.

Kollár, Dániel / Molnár, F Tamás / Zsoldos, Péter / Oláh, Attila

Orvosi hetilap

2018 Volume 159, Issue 2, Page(s) 43–52

Abstract: The management of thoracic and abdominal organ injuries has very thorough and extensive literature, including evidence-based protocols. Pancreatic trauma stands as an exception. Blunt or penetrating trauma of the pancreas is rather rare (less than 2% of ... ...

Title translation	Diagnosis and management of blunt pancreatic trauma.
Abstract	The management of thoracic and abdominal organ injuries has very thorough and extensive literature, including evidence-based protocols. Pancreatic trauma stands as an exception. Blunt or penetrating trauma of the pancreas is rather rare (less than 2% of all trauma cases, approximately 3-12% of all abdominal trauma), leading to the lack of high-level evidences regarding its treatment. Damage of the pancreas parenchyma can cause substantial morbidity and mortality, therefore it is essential to separate cases where conservative treatment suffices from those that need surgical approach. This study aims to review the conclusions of relevant articles of the past decades concerning the management of both adult and childhood pancreatic trauma. Classifications and their reliability are revised. We enlist scaling systems that can help in making decision whether to operate or to treat conservatively, from physical examination to diagnostic measures and complications. To date, the treatment principles of pancreatic trauma are not based either on prospective or on randomised trials. The database search of studies retrieved only retrospective and/or small case cohorts, case reports and expert opinions (levels 4 and 5 of evidence). However, it is a generally accepted conviction that the damage of the main pancreatic duct determines if the pancreatic injury is of low or high grade. Available classifications are based on the same principle. Conservative treatment is feasible given that the patient is hemodinamically stable and the pancreatic duct is unimpaired. If duct lesion is discovered, adult cases are to be treated with minimally invasive (percutaneous or endoscopic) measures or surgically (including reconstruction, resection and drainage). The management of childhood injuries has controversial literature. Many arguments can be enumerated on the operative as also on the non-operative approach, this confusion is to be clarified in the future. The highest morbidity rates are derived from the late diagnosis of the pancreatic duct, while increased mortality is seen in the polytrauma patient groups. Levels 1-2 evidence-based recommendations are needed, but planning of strong trials is critically limited due to the small number of cases and the heterogeneity of the relevant patient groups. Orv Hetil. 2018; 159(2): 43-52.
MeSH term(s)	Child ; Drainage/methods ; Humans ; Pancreas/injuries ; Pancreas/surgery ; Pancreatectomy/methods ; Retrospective Studies ; Wounds, Nonpenetrating/surgery
Language	Hungarian
Publishing date	2018-01
Publishing country	Hungary
Document type	Journal Article ; Review
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2018.30938
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Article ; Online: Systemic versus Oral and Systemic Antibiotic Prophylaxis (SOAP) study in colorectal surgery: prospective randomized multicentre trial.

Papp, G / Saftics, Gy / Szabó, B E / Baracs, J / Vereczkei, A / Kollár, D / Oláh, A / Mészáros, P / Dubóczki, Zs / Bursics, A

The British journal of surgery

2020 Volume 108, Issue 3, Page(s) 271–276

Abstract: Background: There is no consensus regarding the role of mechanical bowel preparation (MBP) and oral antibiotic prophylaxis (OABP) in reducing postoperative complications in colorectal surgery. The aim of this study was to examine the effect of OABP ... ...

Abstract	Background: There is no consensus regarding the role of mechanical bowel preparation (MBP) and oral antibiotic prophylaxis (OABP) in reducing postoperative complications in colorectal surgery. The aim of this study was to examine the effect of OABP given in addition to MBP in the setting of a prospective randomized trial. Methods: Patients awaiting elective colorectal surgery in four Hungarian colorectal centres were included in this multicentre, prospective, randomized, assessor-blinded study. Patients were randomized to receive MBP with or without OABP (OABP+ and OABP- groups respectively). The primary endpoints were surgical-site infection (SSI) and postoperative ileus. Secondary endpoints were anastomotic leak, mortality, and hospital readmission within 30 days. Results: Of 839 patients assessed for eligibility between November 2016 and June 2018, 600 were randomized and 529 were analysed. Trial participation was discontinued owing to adverse events in seven patients in the OABP+ group (2.3 per cent). SSI occurred in eight patients (3.2 per cent) in the OABP+ and 27 (9.8 per cent) in the OABP- group (P = 0.001). The incidence of postoperative ileus did not differ between groups. Anastomotic leakage occurred in four patients (1.6 per cent) in the OABP+ and 13 (4.7 per cent) in the OABP- (P = 0.02) group. There were no differences in hospital readmission (12 (4.7 per cent) versus 10 (3.6 per cent); P = 0.25) or mortality (3 (1.2 per cent) versus 4 (1.4 per cent); P = 0.39). Conclusion: OABP given with MBP reduced the rate of SSI and AL after colorectal surgery with anastomosis, therefore routine use of OABP is recommended.
MeSH term(s)	Aged ; Anastomotic Leak/etiology ; Anastomotic Leak/prevention & control ; Antibiotic Prophylaxis ; Cathartics/administration & dosage ; Colon/surgery ; Enema ; Female ; Hospital Mortality ; Humans ; Ileus/etiology ; Ileus/prevention & control ; Incidence ; Male ; Patient Readmission/statistics & numerical data ; Postoperative Complications/prevention & control ; Prospective Studies ; Rectum/surgery ; Surgical Wound Infection/etiology ; Surgical Wound Infection/prevention & control
Chemical Substances	Cathartics
Language	English
Publishing date	2020-12-07
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	2985-3
ISSN	1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
ISSN (online)	1365-2168
ISSN	0263-1202 ; 0007-1323 ; 1355-7688
DOI	10.1093/bjs/znaa131
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