LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Kolonko, Aureliusz"
  2. AU=Falagas M E
  3. AU="Dunstan, Melanie L"
  4. AU=Kacar Mark AU=Kacar Mark
  5. AU="Schaup, Rebecca Michaela"
  6. AU="Ye, Chaofu"
  7. AU="Tekin, Nur"
  8. AU="Martens, Dirk E"
  9. AU=Teos Leyla Y.
  10. AU="Sánchez-Garcia, Joaquín"
  11. AU="Schaller, Benoit"
  12. AU="Hernandez, A"
  13. AU="Nguyen, Thien H"
  14. AU="Park, Jung Wan"
  15. AU="Mahajan, Aman"
  16. AU="Hao, Yanling"
  17. AU="Eing, Lorenz"
  18. AU="Geoffroy, Pierre A"
  19. AU="Chapuis, J"
  20. AU="Berta, László"
  21. AU="Barzilay, Regina"
  22. AU="Schmidt, Michael Rahbek"
  23. AU=Tack J
  24. AU="Oh, Hye Min"
  25. AU=Gaffen Sarah L AU=Gaffen Sarah L
  26. AU="Schmitt, Christine"
  27. AU="McKay, Jackie"
  28. AU="Bellissimo, Catherine A"
  29. AU="Desai, Urja"
  30. AU="Chini, Maria Giovanna"
  31. AU="Xiao, Difei"
  32. AU="Ryan, Chris"
  33. AU="Omar Bazighifan"
  34. AU="Corominas Galbany, Jordi"
  35. AU=Fox Norma E
  36. AU="Hamilton, Shelia M"
  37. AU="Nichols, J Wylie"
  38. AU="Pesce R."
  39. AU="Gambitta, P"
  40. AU="Imran, Aqeel"
  41. AU="Sharma, Yashoda"
  42. AU="Kosai, Jordyn"
  43. AU="Aroca Ferri, María"
  44. AU="Laba, Stephanie"
  45. AU="Kim, Ye-Sel"

Suchergebnis

Treffer 1 - 10 von insgesamt 56

Suchoptionen

  1. Artikel ; Online: Safety of Antithymocyte Globulin Use in Kidney Graft Recipients During the COVID-19 Pandemic.

    Kolonko, Aureliusz / Więcek, Andrzej

    Annals of transplantation

    2021  Band 26, Seite(n) e933001

    Abstract: BACKGROUND There are many safety concerns regarding the use of antithymocyte globulin (ATG) in kidney transplant recipients (KTRs) during the ongoing COVID-19 pandemic. Hereby, we present our recent experience with ATG administration both as induction ... ...

    Abstract BACKGROUND There are many safety concerns regarding the use of antithymocyte globulin (ATG) in kidney transplant recipients (KTRs) during the ongoing COVID-19 pandemic. Hereby, we present our recent experience with ATG administration both as induction therapy and as an anti-rejection treatment. MATERIAL AND METHODS We retrospectively analyzed all patients transplanted during the first 12 months of the COVID-19 pandemic who were treated with thymoglobulin. The ATG dosing, lymphocyte number and percentage in blood smear, adverse effects (thrombocytopenia and infectious complications), and kidney graft function up to 12 months and patients' outcomes were analyzed and compared to KTRs who received basiliximab induction. RESULTS During pandemic, a total of 31 patients were treated with ATG and 59 received basiliximab. The median cumulative ATG doses were 275 (175-325) mg in the induction subgroup and 263 (200-275) mg in the anti-rejection treatment subgroup. Mild thrombocytopenia was noted in 7 (22.6%) and 13 (29.5%) patients, respectively. There were more infectious complications among patients treated with ATG as compared with the basiliximab subgroup (32.3 vs 10.2%, P<0.01), but there were similar incidence rates of thrombocytopenia. Kidney graft function up to 12 months after transplant was comparable (1.1 [1.0-1.9] vs 1.1 [1.0-1.4] mg/dl, respectively). CONCLUSIONS 1. ATG use in the induction protocol or as the anti-rejection treatment during the COVID-19 pandemic appears to be safe and the risk of adverse events is acceptable. 2. During the COVID-19 pandemic the necessary use of ATG should not be postponed, especially in KTRs with increased immunologic risk.
    Mesh-Begriff(e) Antilymphocyte Serum/adverse effects ; Antilymphocyte Serum/therapeutic use ; Basiliximab/therapeutic use ; COVID-19 ; Graft Rejection/epidemiology ; Graft Rejection/prevention & control ; Graft Survival ; Humans ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Kidney ; Kidney Transplantation ; Pandemics ; Retrospective Studies
    Chemische Substanzen Antilymphocyte Serum ; Immunosuppressive Agents ; Basiliximab (9927MT646M)
    Sprache Englisch
    Erscheinungsdatum 2021-10-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1484710-3
    ISSN 2329-0358 ; 1425-9524
    ISSN (online) 2329-0358
    ISSN 1425-9524
    DOI 10.12659/AOT.933001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5093: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel: Increased EBV DNAemia after Anti-SARS-CoV-2 Vaccination in Solid Organ Transplants.

    Musialik, Joanna / Kolonko, Aureliusz / Więcek, Andrzej

    Vaccines

    2022  Band 10, Heft 7

    Abstract: The reactivation of latent viruses during SARS-CoV-2 infection is well recognized, and coinfection with Epstein−Barr virus (EBV) has been associated with severe clinical cases of COVID-19 infection. In transplant patients, EBV infection presents a ... ...

    Abstract The reactivation of latent viruses during SARS-CoV-2 infection is well recognized, and coinfection with Epstein−Barr virus (EBV) has been associated with severe clinical cases of COVID-19 infection. In transplant patients, EBV infection presents a significant challenge. Assessing the potential impact of SARS-CoV-2 vaccinations on EBV infections in stable kidney and liver transplant recipients was the objective of our study. Ten solid-organ-transplant (SOT) patients (eight kidney and two liver) vaccinated with standard doses of mRNA COVID-19 vaccines were included. EBV DNA viral load measurements were conducted prior to the vaccination and during a follow-up period (at the first month and after six months) after the second vaccine dose. After the second dose, a significant increase in median viremia was observed (p < 0.01) in 9 patients, and in one patient, the reactivation of EBV infection was found. Six months later, the median viremia decreased significantly (p < 0.05). The EBV viral load should be closely monitored as it could lead to the earlier diagnosis and treatment of EBV-related complications. Despite experiencing a decrease in the viral load six months post-vaccination, some patients still had a viral load over the baseline, which increased the risk of potential complications.
    Sprache Englisch
    Erscheinungsdatum 2022-06-22
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10070992
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: Visual evoked potentials as a method for the prospective assessment of tacrolimus neurotoxicity in patients after kidney transplantation.

    Sirek, Sebastian / Kolonko, Aureliusz / Pojda-Wilczek, Dorota

    Documenta ophthalmologica. Advances in ophthalmology

    2022  Band 145, Heft 3, Seite(n) 197–209

    Abstract: Introduction: Neurotoxicity, including optic nerve injury, is one of the most common adverse effects of tacrolimus, the principal calcineurin inhibitor used after kidney transplantation (KTx). The electrophysiologic measurements of both pattern visual ... ...

    Abstract Introduction: Neurotoxicity, including optic nerve injury, is one of the most common adverse effects of tacrolimus, the principal calcineurin inhibitor used after kidney transplantation (KTx). The electrophysiologic measurements of both pattern visual evoked potentials (PVEP) and flash visual evoked potentials (FVEP) are valuable when drug-induced optic neuropathy is suspected.
    Objectives: To determine whether VEP measurement is a sensitive and repeatable method for monitoring tacrolimus neurotoxicity.
    Material and methods: This prospective study focused on 35 patients (20 M, 15F, 69 eyes, mean age 43 ± 11 years) who were at a median of 3.0 (IQR, 2.2-3.7) months after KTx at the time of the initial VEP evaluation and were treated with tacrolimus since KTx. The follow-up VEP examination was done after a median of 24 (22-27) months (both VEP measurements followed the ISCEV standards). The P100 wave latency and amplitude for the 1° and 15' PVEP simulations, and the P2 wave latency and amplitude for the FVEP were analyzed.
    Results: For the 1° checks, the P100 wave latency and amplitude values were significantly worse in the follow-up examination compared to the early post-transplant time-point. Independent associations between FVEP parameters and the tacrolimus blood trough level were observed in the follow-up examination but not at the early post-transplant period. The P2 wave latency correlated with the tacrolimus trough level only in patients treated with the twice-daily, but not the once-daily, tacrolimus formulation. The brain derived neurotrophic factor (BDNF) level correlated with the P100 (15') latency (R = 0.499; p = 0.005) and the P2 latency (R = 0.409; p = 0.025) only in patients treated with the once-daily, but not the twice-daily, tacrolimus formulation.
    Conclusion: The observations in this study may support the rationale for the use of VEP measurements as non-invasive monitoring of subclinical tacrolimus neurotoxicity.
    Mesh-Begriff(e) Humans ; Adult ; Middle Aged ; Evoked Potentials, Visual ; Prospective Studies ; Tacrolimus/adverse effects ; Kidney Transplantation/adverse effects ; Electroretinography
    Chemische Substanzen Tacrolimus (WM0HAQ4WNM)
    Sprache Englisch
    Erscheinungsdatum 2022-10-26
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 212594-8
    ISSN 1573-2622 ; 0012-4486
    ISSN (online) 1573-2622
    ISSN 0012-4486
    DOI 10.1007/s10633-022-09898-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Ul I Zs.100: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel ; Online: Intestinal Permeability in Patients Early after Kidney Transplantation Treated with Two Different Formulations of Once-Daily Tacrolimus.

    Kolonko, Aureliusz / Słabiak-Błaż, Natalia / Pokora, Patrycja / Piecha, Grzegorz / Więcek, Andrzej

    International journal of molecular sciences

    2023  Band 24, Heft 9

    Abstract: Adequate tacrolimus blood exposure is crucial in the early post-renal transplant period and a gut epithelial barrier integrity may play a role. We prospectively investigated several markers of intestinal permeability in recent kidney transplant ... ...

    Abstract Adequate tacrolimus blood exposure is crucial in the early post-renal transplant period and a gut epithelial barrier integrity may play a role. We prospectively investigated several markers of intestinal permeability in recent kidney transplant recipients (KTRs) treated with different tacrolimus extended-release formulations. Within each of the 49 KTR pairs that received grafts from the same donor, an early randomized conversion was performed from twice-daily (Prograf) to once-daily tacrolimus formulation: Advagraf or Envarsus. Plasma zonulin, calprotectin, circulating lipopolysaccharide (LPS), LPS-binding protein (LBP), intestinal fatty acid binding protein (FABP-2), and CD-14 levels were measured. There was no difference in the recipient age, dialysis vintage, BMI, and residual diuresis between Advagraf and Envarsus groups. FABP-2 and LPS levels were significantly associated with tacrolimus trough level, 3-h level, and area under the curve (AUC) in the Envarsus but not in the Advagraf group. AUC was independently increased by LPS and decreased by age, FABP-2 concentration, and the use of Envarsus formulation as compared with Advagraf. Functional changes of gastrointestinal tract in patients treated with Envarsus may influence intestinal tacrolimus absorption to a greater extent than in Advagraf-treated KTRs and may lead to inadequate variability of tacrolimus exposure early after kidney transplantation.
    Mesh-Begriff(e) Humans ; Tacrolimus ; Kidney Transplantation ; Immunosuppressive Agents ; Lipopolysaccharides ; Renal Dialysis ; Delayed-Action Preparations ; Graft Rejection
    Chemische Substanzen Tacrolimus (WM0HAQ4WNM) ; Immunosuppressive Agents ; Lipopolysaccharides ; Delayed-Action Preparations
    Sprache Englisch
    Erscheinungsdatum 2023-05-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24098344
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: Clinical Outcomes of Transplanted Kidneys from Deceased Donors Using Different Generic Preservation Solutions.

    Kolonko, Aureliusz / Słabiak-Błaż, Natalia / Król, Robert / Więcek, Andrzej

    Medicina (Kaunas, Lithuania)

    2022  Band 58, Heft 11

    Abstract: Background and Objectives: StoreProtect Plus® is a preserving solution for cold organ storage, with a composition identical to Institute Georges Lopez (IGL-1) solution. The aim of this single center study was to compare the clinical performance of ... ...

    Abstract Background and Objectives: StoreProtect Plus® is a preserving solution for cold organ storage, with a composition identical to Institute Georges Lopez (IGL-1) solution. The aim of this single center study was to compare the clinical performance of StoreProtect Plus with the generic counterpart of University of Wisconsin preservation fluid, named SPS-1®. Materials and Methods: The clinical outcomes of 168 consecutive organs preserved with StoreProtect Plus solution and 167 organs preserved with SPS-1 solution were compared. During an 18-month post-transplant follow-up period, kidney graft function, the frequency of acute rejection, post-transplant diabetes, and infectious complications, as well as patient and graft survival were analyzed. Results: There was significantly more immediate graft function (IGF) (39.3 vs. 24.0%; p < 0.01) and less slow graft function (SGF) (38.7 vs. 51.5%; p < 0.05) in the StoreProtect Plus group in comparison with the SPS-1 group, whereas the occurrence of DGF was similar in both groups. Long-term kidney graft function was comparable. Multivariate regression analysis showed that the use of StoreProtect Plus vs. SPS-1 solution (rpartial = 0.217; p < 0.001) and the amount of residual diuresis (rpartial = 0.147; p < 0.001) independently increased the occurrence of IGF, whereas Scr > 1.5 mg/dL prior to organ procurement (rpartial = −0.198; p < 0.001), longer CIT (rpartial = −0.170; p < 0.01), and CVD donor death (rpartial = −0.214; p < 0.001) were associated with SGF. Conclusions: The higher occurrence of IGF was found in kidney transplant recipients whose organs were preserved using StoreProtect Plus solution as compared with SPS-1 solution. The two groups did not differ in kidney graft function, the frequency of post-transplant complications, as well as patient and graft survival.
    Mesh-Begriff(e) Humans ; Tissue Donors ; Graft Survival ; Kidney Transplantation/adverse effects ; Tissue and Organ Procurement ; Kidney/surgery
    Sprache Englisch
    Erscheinungsdatum 2022-11-02
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58111579
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6270: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  6. Artikel ; Online: COVID-19 infection in solid organ transplant recipients: A single-center experience with patients immediately after transplantation.

    Kolonko, Aureliusz / Dudzicz, Sylwia / Wiecek, Andrzej / Król, Robert

    Transplant infectious disease : an official journal of the Transplantation Society

    2020  Band 23, Heft 1, Seite(n) e13381

    Abstract: In our transplant center, infection with SARS-CoV-2 virus was confirmed in 4 organ transplant recipients (3 kidney and 1 liver transplant recipients) during their early post-transplant hospital stay. In this paper, we report the basic characteristics, ... ...

    Abstract In our transplant center, infection with SARS-CoV-2 virus was confirmed in 4 organ transplant recipients (3 kidney and 1 liver transplant recipients) during their early post-transplant hospital stay. In this paper, we report the basic characteristics, management, clinical course, and outcomes of these patients.
    Mesh-Begriff(e) Adult ; COVID-19/complications ; Fatal Outcome ; Humans ; Immunocompromised Host ; Immunosuppressive Agents/administration & dosage ; Kidney Transplantation ; Liver Transplantation ; Male ; Middle Aged ; SARS-CoV-2 ; Transplant Recipients ; Young Adult
    Chemische Substanzen Immunosuppressive Agents
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-07-06
    Erscheinungsland Denmark
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13381
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5100: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  7. Artikel: Association between Kidney Donor Risk Index, kidney graft function and histological changes in early post-transplant graft biopsy.

    Słabiak-Błaż, Natalia / Kujawa-Szewieczek, Agata / Kolonko, Aureliusz / Ziółkowska, Joanna / Karkoszka, Henryk / Więcek, Andrzej / Piecha, Grzegorz

    Clinical kidney journal

    2023  Band 16, Heft 11, Seite(n) 2226–2234

    Abstract: Background: Proper assessment of donor organ quality is crucial for optimal kidney allocation and best long-term outcomes. The aim of this study was to analyze the association between the Kidney Donor Risk Index (KDRI) and histological parameters in ... ...

    Abstract Background: Proper assessment of donor organ quality is crucial for optimal kidney allocation and best long-term outcomes. The aim of this study was to analyze the association between the Kidney Donor Risk Index (KDRI) and histological parameters in early post-transplant graft biopsy in a Polish cohort of kidney transplant recipients.
    Methods: In 418 consecutive kidney transplant recipients, a histological evaluation of very early [at median 11 (9-13) post-transplant day] protocol core needle biopsy was performed and analyzed according to the Banff classification. Subjects were divided into quartiles of the KDRI value. Kidney graft function, patient and graft survival were also analyzed over a median follow-up period of 44 (26-56) months.
    Results: There was a significant trend toward greater intensity of chronic histology changes along the KDRI quartiles (χ
    Conclusion: The KDRI values correlate with chronic histological changes found in early post-implantation kidney biopsies and can also be helpful in the prediction of graft outcome.
    Sprache Englisch
    Erscheinungsdatum 2023-06-15
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad124
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6587: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  8. Artikel ; Online: Lung Ultrasound B-lines Occurrence in Relation to Left Ventricular Function and Hydration Status in Hemodialysis Patients.

    Pardała, Agnieszka / Lupa, Mariusz / Chudek, Jerzy / Kolonko, Aureliusz

    Medicina (Kaunas, Lithuania)

    2019  Band 55, Heft 2

    Abstract: Background and objective: Reliable assessment of the fluid status in hemodialysis (HD) patients is often difficult. A lung ultrasound with an assessment of the B-lines ("lung comets" (LCs)) number is a novel hydration status measure. However, the ... ...

    Abstract Background and objective: Reliable assessment of the fluid status in hemodialysis (HD) patients is often difficult. A lung ultrasound with an assessment of the B-lines ("lung comets" (LCs)) number is a novel hydration status measure. However, the occurrence of left ventricular dysfunction may have a significant effect on pulmonary congestion and further modulate the LC number. The aim of this study was to analyze to what extent left ventricular dysfunction, pulmonary hypertension, and hypervolemia affect the occurrence of LC in a cohort of prevalent HD patients.
    Material and methods: This cross-sectional study included 108 assessments performed in 54 patients who attended thrice weekly outpatient HD. Each patient's fluid status was evaluated twice, prior to HD sessions, using echocardiography, LC number assessment, measurement of inferior vena cava (IVC) diameters, and bioelectric impedance analysis (BIA). Patients were stratified into three subgroups according to their LC number.
    Results: There were 76 separate assessments with mild (<14), 16 with moderate (14⁻30), and 16 with severe (>30) LC occurrence. There was a negative correlation between the LC number and left ventricular ejection fraction (LVEF), and positive correlations between the LC number and mitral gradient, and the left and right atrium area and volume, but not with the BIA-derived relative fluid overload. Multivariate linear regression analysis revealed that the LC number was proportionally related to the mitral gradient (β = 0.407 (0.247⁻0.567), p < 0.001) and IVC max diameter (β = 0.219 (0.060⁻0.378), p < 0.01), and was inversely related to LVEF (β = -0.431 (-0.580 to -0.282), p < 0.001).
    Conclusions: The number of LCs appears to reflect both overhydration and left ventricular dysfunction in our HD patients cohort. Therefore, heart failure must be considered as an important factor limiting the usefulness of LCs number assessment in this population.
    Mesh-Begriff(e) Aged ; Carotid Artery, Common/diagnostic imaging ; Cohort Studies ; Cross-Sectional Studies ; Echocardiography ; Electric Impedance ; Extravascular Lung Water/diagnostic imaging ; Extravascular Lung Water/physiology ; Female ; Humans ; Hypertension, Pulmonary/etiology ; Linear Models ; Lung/diagnostic imaging ; Male ; Middle Aged ; Organism Hydration Status ; Renal Dialysis/adverse effects ; Renal Insufficiency, Chronic/therapy ; Ultrasonography ; Vena Cava, Inferior/physiology ; Ventricular Dysfunction, Left/etiology ; Ventricular Function, Left/physiology
    Sprache Englisch
    Erscheinungsdatum 2019-02-12
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina55020045
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 6270: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  9. Artikel ; Online: Advanced Leiomyosarcoma of the Retroperitoneal Space in a Kidney Transplant Recipient with a History of Peritoneal Dialysis: A Case Report.

    Kaźmierczak, Olga / Kozaczka, Anna / Kolonko, Aureliusz / Kajor, Maciej / Pająk, Jacek / Chudek, Jerzy

    The American journal of case reports

    2021  Band 22, Seite(n) e933267

    Abstract: BACKGROUND Leiomyosarcoma frequently occurs in patients who are on immunosuppressive therapy. It is the second most common sarcoma in this population and is often associated with Epstein-Barr virus (EBV) infection. We present a case of advanced ... ...

    Abstract BACKGROUND Leiomyosarcoma frequently occurs in patients who are on immunosuppressive therapy. It is the second most common sarcoma in this population and is often associated with Epstein-Barr virus (EBV) infection. We present a case of advanced leiomyosarcoma of the retroperitoneal space in a kidney transplant recipient and discuss additional risk factors for oncogenesis. CASE REPORT A 44-year-old woman with a history of peritoneal dialysis and kidney transplantation was diagnosed with multiple liver lesions. PET-CT scanning showed a metabolically active tumor in the left lumbar region with numerous liver focal lesions. The histological examination of the liver lesion biopsy identified advanced retroperitoneal leiomyosarcoma with a high proliferative index and liver involvement. Unexpectedly, the relation with EBV infection was not proven. The patient was treated with first-line doxorubicin, with the simultaneous reduction of immunosuppression. Owing to disease progression after 6 cycles, the patient received second-line chemotherapy based on gemcitabine and docetaxel, which was terminated owing to unacceptable toxicity, despite an observed response. Third-line trabectedin-based therapy with good tolerance and stabilization of disease after 20 months was being maintained at the time of this report. CONCLUSIONS The increased cancer mortality in solid-organ transplant recipients requires an individualized approach and increased post-transplantation screening according to additional specific cancer risk factors. A further consideration is the hypothetical relevance of long-term peritoneal membrane irritation in peritoneal dialysis patients.
    Mesh-Begriff(e) Adult ; Epstein-Barr Virus Infections ; Female ; Herpesvirus 4, Human ; Humans ; Kidney Transplantation/adverse effects ; Leiomyosarcoma/complications ; Peritoneal Dialysis/adverse effects ; Positron Emission Tomography Computed Tomography ; Retroperitoneal Space
    Sprache Englisch
    Erscheinungsdatum 2021-10-25
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.933267
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  10. Artikel: COVID-19 infection in solid organ transplant recipients: A single-center experience with patients immediately after transplantation

    Kolonko, Aureliusz / Dudzicz, Sylwia / Wiecek, Andrzej / Król, Robert

    Transpl Infect Dis

    Abstract: In our transplant center, infection with SARS-CoV-2 virus was confirmed in 4 organ transplant recipients (3 kidney and 1 liver transplant recipients) during their early post-transplant hospital stay. In this paper, we report the basic characteristics, ... ...

    Abstract In our transplant center, infection with SARS-CoV-2 virus was confirmed in 4 organ transplant recipients (3 kidney and 1 liver transplant recipients) during their early post-transplant hospital stay. In this paper, we report the basic characteristics, management, clinical course, and outcomes of these patients.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #610837
    Datenquelle COVID19

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang