Article: [Brain-derived neurotrophic factor gene (BDNF) polymorphism among Moscow citizens].
2014 Volume 49, Issue 12, Page(s) 1432–1435
Abstract: Recent studies showed that brain-derived neurotrophic factor (BDNF) can participate in pathogenesis of various CNS disorders, being connected with proliferation, differentiation, and survival of neurons. In present study, analysis of occurrence rate was ... ...
| Abstract | Recent studies showed that brain-derived neurotrophic factor (BDNF) can participate in pathogenesis of various CNS disorders, being connected with proliferation, differentiation, and survival of neurons. In present study, analysis of occurrence rate was performed for three single nucleotide polymorphisms (SNPs) located in BDNF gene (rs6267 (A/G) allele A-0.265; rs2049046 (A/T) allele A-0.407; rs11030107 (A/G) allele A-0.872) in randomized selection of Moscow citizens. Linkage disequilibrium of rs6165 and rs2049046 loci was shown. Differences in allele frequencies in studied selection and populations of other re- gions were discovered. |
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| MeSH term(s) | Adolescent ; Adult ; Brain-Derived Neurotrophic Factor/genetics ; Female ; Gene Frequency ; Humans ; Linkage Disequilibrium ; Male ; Middle Aged ; Moscow ; Polymorphism, Single Nucleotide |
| Chemical Substances | Brain-Derived Neurotrophic Factor ; BDNF protein, human (7171WSG8A2) |
| Language | Russian |
| Publishing date | 2014-11-25 |
| Publishing country | Russia (Federation) |
| Document type | Journal Article |
| ZDB-ID | 216714-1 |
| ISSN | 0016-6758 |
| ISSN | 0016-6758 |
| DOI | 10.7868/s0016675813120047 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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