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Article ; Online: Post-Bariatric Panniculectomy: Postoperative Complications by Weight Loss Surgery Type.

Fahmy, Joseph N / Kong, Lingxuan / Benítez, Trista M / Sanders, Hayley M / Wang, Lu / Chung, Kevin C

2024

Abstract: Background: Over 250,000 patients undergo bariatric surgery each year in the United States. Approximately 21% will undergo subsequent body contouring after massive weight loss. Patients with prior bariatric surgery are at a greater risk for ... ...

Abstract	Background: Over 250,000 patients undergo bariatric surgery each year in the United States. Approximately 21% will undergo subsequent body contouring after massive weight loss. Patients with prior bariatric surgery are at a greater risk for complications relative to the general population. However, it is unknown if bariatric surgery type is associated with differential complication risk after panniculectomy. Methods: A retrospective chart review of post-bariatric who underwent abdominal panniculectomy at a single large quaternary care center was performed. Postoperative complications were graded according to the Clavien-Dindo classification. Descriptive statistics, multivariable logistic regression, and power calculations were performed. Results: In total, 216 patients were included. Restrictive bariatric surgery accounted for 48.6% while 51.3% had a history of malabsorptive bariatric surgery. The overall rate of complications was 34.3% (restrictive: 36.2%; malabsorptive: 32.8%, p=0.66). Wound complications were observed in 25.5% (n=55) of patients. Systemic complications occurred in 11.1% of patients overall, with statistically similar rates between restrictive and malabsorptive groups. After adjusting for both patient and operative factors, no significant difference in total complications (OR=1.15, 95% CI: 0.47 to 2.85, p=0.76), systemic complications (OR=0.26, 95% CI: 0.05 to 1.28, p=0.10), or wound complications (OR=2.31, 95% CI: 0.83 to 6.41, p=0.11) was observed. Conclusions: Complications following panniculectomy in bariatric surgery patients is high and predominantly related to wound healing. No significant difference between type of bariatric surgery and complication risk was found.
Language	English
Publishing date	2024-02-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000011365
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Article ; Online: Cimifugin Relieves Histamine-Independent Itch in Atopic Dermatitis via Targeting the CQ Receptor MrgprA3.

Zheng, Jie / Gu, Anqi / Kong, Lingxuan / Lu, Wenhan / Xia, Jingsheng / Hu, Huijuan / Hong, Min

ACS omega

2024 Volume 9, Issue 6, Page(s) 7239–7248

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2024-01-31
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c09697
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Article: Uptake and translocation mechanisms of different forms of organic selenium in rice (

Wang, Qi / Kong, Lingxuan / Huang, Qingqing / Li, Huafen / Wan, Yanan

Frontiers in plant science

2022 Volume 13, Page(s) 970480

Abstract: Selenium (Se) is an essential trace element for human and animal health, and toward an understanding of the uptake and translocation of Se in plants is important from the perspective of Se biofortification. In this study, we conducted hydroponic ... ...

Abstract	Selenium (Se) is an essential trace element for human and animal health, and toward an understanding of the uptake and translocation of Se in plants is important from the perspective of Se biofortification. In this study, we conducted hydroponic experiments to investigate the mechanisms of organic Se [selenomethionine (SeMet) and selenomethionine-oxide (SeOMet)] uptake, translocation, and the interactions between SeMet and SeOMet in rice. We also investigated differences in the dynamics of organic and inorganic Se uptake by rice roots. Concentration-dependent kinetic results revealed that SeMet uptake during a 1 h exposure was 3.19-16.0 times higher than that of three other Se chemical forms, with uptake capacity (
Language	English
Publishing date	2022-08-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2022.970480
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Article ; Online: Dual-Conductive and Stiffness-Morphing Microneedle Patch Enables Continuous In Planta Monitoring of Electrophysiological Signal and Ion Fluctuation.

Kong, Lingxuan / Wen, Hanqi / Luo, Yifei / Chen, Xiaodong / Sheng, Xing / Liu, Yuxin / Chen, Peng

ACS applied materials & interfaces

2023 Volume 15, Issue 37, Page(s) 43515–43523

Abstract: The use of conductive microneedles presents a promising solution for achieving high-fidelity electrophysiological recordings with minimal impact on the interfaced tissue. However, a conventional metal-based microneedle suffers from high electrochemical ... ...

Abstract	The use of conductive microneedles presents a promising solution for achieving high-fidelity electrophysiological recordings with minimal impact on the interfaced tissue. However, a conventional metal-based microneedle suffers from high electrochemical impedance and mechanical mismatch. In this paper, we report a dual-conductive (i.e., both ionic and electronic conductive) and stiffness-morphing microneedle patch (DSMNP) for high-fidelity electrophysiological recordings with reduced tissue damage. The polymeric network of the DSMNP facilitates electrolyte absorption and therefore allows the transition of stiffness from 6.82 to 0.5139 N m
MeSH term(s)	Ions ; Electric Conductivity ; Electric Impedance ; Action Potentials ; Agriculture ; Polymers
Chemical Substances	Ions ; Polymers
Language	English
Publishing date	2023-09-07
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c08783
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Article ; Online: Compound Muscle Action Potential Amplitude as a Predictor of Functional and Patient-Reported Outcomes in Ulnar Neuropathy at the Elbow.

Florczynski, Matthew M / Kong, Lingxuan / Burns, Patricia B / Wang, Lu / Chung, Kevin C

Plastic and reconstructive surgery

2023 Volume 151, Issue 6, Page(s) 1247–1255

Abstract: Background: Ulnar neuropathy at the elbow (UNE) is a debilitating upper extremity condition that often leaves patients with residual symptoms even after surgical treatment. The role of electrodiagnostic studies in guiding the treatment of UNE is not ... ...

Abstract	Background: Ulnar neuropathy at the elbow (UNE) is a debilitating upper extremity condition that often leaves patients with residual symptoms even after surgical treatment. The role of electrodiagnostic studies in guiding the treatment of UNE is not well established, and conventional electrodiagnostic parameters may not reflect the severity of disease. Compound muscle action potential (CMAP) amplitude is a parameter that corresponds with axonal injury and motor symptoms and may more accurately predict the severity of neurologic injury. Methods: This prospective multicenter study recruited 78 patients in the Surgery of the Ulnar Nerve project. Patients underwent electrodiagnostic testing and clinical assessment of motor and sensory function, and completed patient-reported outcome questionnaires, including the Michigan Hand Outcome Questionnaire; the Disabilities of the Arm, Shoulder and Hand questionnaire; and the Carpal Tunnel Questionnaire (CTQ). Correlations were measured among each of the electrodiagnostic parameters and outcomes and predictive models for each outcome were subsequently developed. Results: Of all the electrodiagnostic parameters measured, only CMAP amplitude was predictive of scores on the Michigan Hand Outcome Questionnaire; Disabilities of the Arm, Shoulder and Hand questionnaire; CTQ function scale, and motor impairment in grip and pinch strength. None of the parameters were predictive of scores on the CTQ symptom scale or sensory impairments as measured with two-point discrimination or Semmes-Weinstein monofilament testing. Conclusions: CMAP amplitude, but not other conventional electrodiagnostic parameters, is predictive of functional outcomes in UNE. This electrodiagnostic measurement can alert the clinician to severe cases of UNE and inform surgical decision-making. Clinical question/level of evidence: Risk, III.
MeSH term(s)	Humans ; Elbow/surgery ; Action Potentials/physiology ; Prospective Studies ; Ulnar Neuropathies/diagnosis ; Ulnar Neuropathies/surgery ; Ulnar Nerve ; Patient Reported Outcome Measures ; Carpal Tunnel Syndrome ; Muscles
Language	English
Publishing date	2023-01-03
Publishing country	United States
Document type	Multicenter Study ; Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000010163
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Article ; Online: Predictors and Variation in Steroid Injection Use for Carpal Tunnel Syndrome from a Multicenter Quality Collaborative.

Billig, Jessica I / Kotsis, Sandra V / Kong, Lingxuan / Wang, Lu / Chung, Kevin C

Plastic and reconstructive surgery

2023 Volume 153, Issue 5, Page(s) 1075–1082

Abstract: Background: Steroid injections are commonly used as first-line treatment for carpal tunnel syndrome (CTS); however, research has shown that their benefit is generally short term, and many patients go on to receive carpal tunnel release (CTR). The ... ...

Abstract	Background: Steroid injections are commonly used as first-line treatment for carpal tunnel syndrome (CTS); however, research has shown that their benefit is generally short term, and many patients go on to receive carpal tunnel release (CTR). The purpose of this study was to determine the variation in steroid injection use by hand surgeons. Methods: The authors analyzed data from a nine-center hand surgery quality collaborative. Data from 1586 patients (2381 hands) were included if they underwent elective CTR at one of the sites. Mixed effects logistic regression models were used to examine the association of receipt of steroid injection and association of receipt of more than one steroid injection among patient-level covariates. Results: Steroid injection use significantly varied by practice, ranging from 12% to 53% of patients. The odds of receiving a steroid injection were 1.4 times higher for women ( P < 0.01), 1.6 times higher for patients with chronic pain syndrome ( P < 0.01), 0.5 times lower for patients with moderate electromyography (EMG) classification, and 0.4 times lower for patients with severe EMG classification (both P < 0.01). Patients with high scores on the Six-Item CTS Scale ( P = 0.02) and patients with moderate ( P = 0.04) or severe EMG ( P = 0.05) classification had lower odds of receiving multiple steroid injections. Complete symptomatic improvement after steroid injection was significantly reported by patients with a high Six-Item CTS Scale score ( P = 0.03) and patients with severe EMG classification ( P = 0.02). Conclusions: The authors found wide patient-level and practice-level variation in the use of steroid injections before CTR. These findings underscore the need for improved data and standard practice guidelines regarding which patients benefit from steroid injection. Clinical question/level of evidence: Risk, III.
MeSH term(s)	Humans ; Carpal Tunnel Syndrome/drug therapy ; Carpal Tunnel Syndrome/surgery ; Female ; Male ; Middle Aged ; Aged ; Practice Patterns, Physicians'/statistics & numerical data ; Steroids/administration & dosage ; Adult ; Injections, Intra-Articular ; Injections ; Glucocorticoids/administration & dosage ; Treatment Outcome ; Retrospective Studies
Chemical Substances	Steroids ; Glucocorticoids
Language	English
Publishing date	2023-06-27
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000010899
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Uk I Zs.142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Impact of consensus guideline publication on the timing of elective pediatric umbilical hernia repair.

Benítez, Trista M / Kim, You J / Kong, Lingxuan / Wang, Lu / Chung, Kevin C

Surgery

2023 Volume 174, Issue 6, Page(s) 1281–1289

Abstract: Background: The American Academy of Pediatrics published consensus guidelines advising observation of asymptomatic umbilical hernias until age 4 or 5, given unnecessary risks of early intervention and substantial practice variation. Yet, the impact of ... ...

Abstract	Background: The American Academy of Pediatrics published consensus guidelines advising observation of asymptomatic umbilical hernias until age 4 or 5, given unnecessary risks of early intervention and substantial practice variation. Yet, the impact of guidelines on early repair (age <4) or if certain groups remain at risk for avoidable intervention is unclear. Methods: This retrospective study used data from children's hospitals participating in the Pediatric Health Information System database. Children aged 17 years and younger who underwent umbilical hernia repair from July 2017 to August 2022 were eligible for inclusion. Children with recurrent hernias, an emergency, or urgent presentation were excluded. An interrupted time series using segmented multivariable logistic regression estimated the association of guideline publication in November 2019 with the odds of guideline-adherent repair (age ≥4) after adjusting for sociodemographic characteristics and hospital-level random effects. Results: 16,544 children underwent repair, of which 3,115 (18.8%) were children <4 years old. After adjustment, guideline publication was associated with an immediate increase in guideline-adherent repairs (odds ratio = 1.25 95% confidence interval = 1.05-1.49). The interrupted time series found that each month after publication was associated with a 2% increase in the odds of guideline-adherent repair (odds ratio = 1.02, 95% confidence interval = 1.01-1.03). Children with public insurance were nearly 20% less likely to receive guideline-adherent repair than privately insured children (odds ratio = 0.82, 95% confidence interval = 0.74-0.91). Children in the Midwest had lower odds of guideline-adherent repair (Midwest versus Northeast: odds ratio = 0.45. 95% confidence interval = 0.24-0.84). Conclusion: Guideline publication was associated with greater odds of guideline-adherent repair, yet public insurance coverage and Midwest location remain significant predictors of early repair against recommendations.
MeSH term(s)	Humans ; Child ; Child, Preschool ; Hernia, Umbilical/surgery ; Retrospective Studies ; Consensus ; Databases, Factual ; Hospitals, Pediatric
Language	English
Publishing date	2023-08-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	202467-6
ISSN	1532-7361 ; 0039-6060
ISSN (online)	1532-7361
ISSN	0039-6060
DOI	10.1016/j.surg.2023.07.024
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Article ; Online: Association of Screen Time with Anxiety and Depressive Symptoms in College Students During COVID-19 Outbreak in Shanghai: Mediation Role of Sleep Quality.

Liu, Yiting / Sun, Yishan / Zheng, Kefeng / Zheng, Jiaxin / Kong, Lingxuan / Gu, Jianping / Huang, Tao

Cyberpsychology, behavior and social networking

2023 Volume 26, Issue 10, Page(s) 755–763

Abstract: The study aimed to investigate the associations between different types of screen time (ST) and anxiety and depressive symptoms in college students during the Coronavirus disease 2019 (COVID-19) outbreak in Shanghai, China; the potential mediation role ... ...

Abstract	The study aimed to investigate the associations between different types of screen time (ST) and anxiety and depressive symptoms in college students during the Coronavirus disease 2019 (COVID-19) outbreak in Shanghai, China; the potential mediation role of sleep quality was also examined. A total of 1,550 college students completed an online survey in May 2022. ST, Self-rating Anxiety Scale (SAS) score, Self-rating Depression Scale (SDS) score, Pittsburgh Sleep Quality Index (PSQI) score, and physical activity were self-reported. Multiple linear regression and mediation analysis were conducted. The results showed that more time spent in TV/movie viewing (>2 h/day) and recreational reading (>1 h/day) was associated with higher levels of anxiety, while more time spent in online social media (>2 h/day) was associated with a higher level of depressive symptoms. In contrast, time spent in online social media (1-2 h/day) was associated with a lower level of anxiety. Meanwhile, recreational reading (2-3 h/day) had a significant indirect effect on anxiety and depressive symptoms through sleep quality. During the COVID-19 outbreak, the associations of ST with anxiety and depressive symptoms varied by the type of screen viewing in college students. The associations of slightly excessive time spent on recreational reading with higher levels of anxiety and depressive symptoms were partially mediated by sleep quality.
Language	English
Publishing date	2023-09-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2545735-4
ISSN	2152-2723 ; 2152-2715
ISSN (online)	2152-2723
ISSN	2152-2715
DOI	10.1089/cyber.2022.0373
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Article ; Online: Screen-based sedentary behaviors but not total sedentary time are associated with anxiety among college students.

Huang, Tao / Zheng, Kefeng / Li, Shiyuan / Yang, Yanxiang / Kong, Lingxuan / Zhao, Ying

Frontiers in public health

2022 Volume 10, Page(s) 994612

Abstract: Objective: The purpose of the study was to investigate the associations of device-measured total sedentary time and screen-based sedentary time with anxiety in college students.: Methods: Three hundred and twenty-one college students (mean age = 19 ... ...

Abstract	Objective: The purpose of the study was to investigate the associations of device-measured total sedentary time and screen-based sedentary time with anxiety in college students. Methods: Three hundred and twenty-one college students (mean age = 19.72 ± 1.18, 55.8% females) were recruited from Shanghai, China. Total sedentary time was objectively measured using accelerometry, while screen-based sedentary time was self-reported. Anxiety symptom was evaluated using the Self-Rating Anxiety Scale. Linear regression modeling was used to assess the associations of total sedentary time and screen-based sedentary time with anxiety symptom. Results: Accelerometer-assessed total sedentary time was not associated with anxiety symptom. Prolonged sedentary time on TV and movie viewing (>2 h on weekdays) and social media using (>2 h on weekdays and weekend) were associated with a higher level of anxiety. However, time on video gaming and recreational reading was not associated with anxiety symptom. Conclusion: The findings indicated that screen-based sedentary behaviors but not total sedentary time were associated with anxiety symptom among college students. The associations of screen-based sedentary behaviors with anxiety symptom varied by the types of screen time.
MeSH term(s)	Female ; Humans ; Male ; Sedentary Behavior ; Cross-Sectional Studies ; China/epidemiology ; Students ; Anxiety/epidemiology
Language	English
Publishing date	2022-10-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.994612
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Article ; Online: Association Between Daytime vs Overnight Digit Replantation and Surgical Outcomes.

Lin, I-Chun F / Yoon, Alfred P / Kong, Lingxuan / Wang, Lu / Chung, Kevin C

JAMA network open

2022 Volume 5, Issue 9, Page(s) e2229526

Abstract: Importance: Recent evidence suggests that select delayed replantation may not adversely affect digit survival; however, whether surgical timing (overnight or daytime) is associated with digit replantation outcomes is unknown.: Objective: To assess ... ...

Abstract	Importance: Recent evidence suggests that select delayed replantation may not adversely affect digit survival; however, whether surgical timing (overnight or daytime) is associated with digit replantation outcomes is unknown. Objective: To assess whether digit survival, complication rate, and duration of surgery are associated with time of replantation. Design, setting, and participants: This retrospective case series study included all replantations performed at a single tertiary referral academic center between January 1, 2000, and August 1, 2021. Data were analyzed between October 2, 2021, and January 1, 2022. Four daytime surgery intervals were selected based on literature review. Daytime replantations started within the intervals whereas overnight replantations began outside the intervals. For each case, the procedure difficulty score and the attending surgeon expertise score were calculated. Logistic and linear regressions adjusting for confounders including procedure difficulty score and expertise score were used to assess surgical timing and outcomes. Participants were adults (aged ≥18 years) undergoing digit replantations between January 2000 and August 2021 with at least 1-month follow-up. Replantation was defined as the reattachment of a completely amputated digit that necessitated anastomosis of both artery and vein. Exposures: Daytime or overnight digit replantation. Main outcomes and measures: Viable replanted digit at 1-month follow-up, number of complications, and duration of surgery. Results: A total of 98 patients (mean [SD] age, 39.5 [15.3] years; 136 [93%] men) and 147 digits met inclusion criteria. Overall success rate was 55%. Between 4 pm and 7 am, overnight replantations were associated with 0.4 fewer complications (β, -0.4; 95% CI, -0.8 to -0.1) and 90.7 minutes shorter operative time (β, -90.7; 95% CI, -173.6 to -7.7). A 1-point increase in surgeon expertise score was associated with 1.7 times increased odds of replantation success for all intervals (adjusted odds ratio, 1.7; 95% CI, 1.2 to 2.4; P = .002). There were no differences in digit survival by surgical time. Conclusions and relevance: In this case series study of digit replantations, time of operation was not associated with replantation success. Overnight replantation was associated with fewer complications and shorter duration of surgery compared with daytime surgery. Results of this study suggest that overnight replantations may be performed with outcomes comparable to daytime replantations at a tertiary care academic center.
MeSH term(s)	Adolescent ; Adult ; Amputation, Traumatic/surgery ; Female ; Finger Injuries/surgery ; Humans ; Male ; Replantation ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2022-09-01
Publishing country	United States
Document type	Journal Article
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2022.29526
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