Article ; Online: Selective Versus Comprehensive Neck Dissection in Patients With T1 and T2 Oral Squamous Cell Carcinoma and cN0pN(+) Neck.
2016 Volume 74, Issue 6, Page(s) 1271–1276
Abstract: Purpose: There is still no consensus on the oncologic safety of selective neck dissection (SND) in the management of pathologically positive neck in patients with oral squamous cell carcinoma (OSCC). This study compared the clinical outcome between SND ... ...
| Abstract | Purpose: There is still no consensus on the oncologic safety of selective neck dissection (SND) in the management of pathologically positive neck in patients with oral squamous cell carcinoma (OSCC). This study compared the clinical outcome between SND and comprehensive neck dissection (CND) for patients with T1 and T2 OSCC and a clinically negative but pathologically positive neck. Materials and methods: Retrospective study of medical records of patients with T1 and T2 OSCC and clinical N0 but pathologic N(+) disease from March 2000 through March 2011 was performed. Thirty-seven patients underwent SND or CND. Median follow-up was 51 months. Regional control and disease-specific survival rates were statistically analyzed. Results: No significant differences in 3-year ipsilateral neck control rate (81.8 vs 91.7%; P = .590 by log-rank test) and overall regional control rate (72.7 vs 86.8%; P = .424 by log-rank test) were found between the SND and CND groups. Three-year disease-specific survival rates of the SND and CND groups were 72.7 and 82.1%, respectively. No significant difference was found between these 2 groups by log-rank test (P = .428). Conclusions: The results indicate that SND in conjunction with postoperative radiotherapy is effective in the management of patients with T1 and T2 OSCC and cN0pN(+) neck. |
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| MeSH term(s) | Adult ; Aged ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Mouth Neoplasms/pathology ; Mouth Neoplasms/surgery ; Neck Dissection/methods ; Retrospective Studies ; Survival Analysis | |||||
| Language | English | |||||
| Publishing date | 2016-06 | |||||
| Publishing country | United States | |||||
| Document type | Comparative Study ; Journal Article | |||||
| ZDB-ID | 392404-x | |||||
| ISSN | 1531-5053 ; 0278-2391 | |||||
| ISSN (online) | 1531-5053 | |||||
| ISSN | 0278-2391 | |||||
| DOI | 10.1016/j.joms.2016.01.001 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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