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Article: [Vitamins and Immune System Health].

Kong, Wei-Li / Lu, Xin-Rong / Hou, Lin-Lin / Sun, Xiu-Fa / Sun, Gui-Qin / Chen, Li

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

2023 Volume 54, Issue 1, Page(s) 7–13

Abstract: Keeping the immune system healthy forms an effective way to fight infections. Past experience has shown that, in addition to effective interventions including vaccination, drug therapy, and non-pharmaceutical intervention (NPI), dietary nutrition and ... ...

Abstract	Keeping the immune system healthy forms an effective way to fight infections. Past experience has shown that, in addition to effective interventions including vaccination, drug therapy, and non-pharmaceutical intervention (NPI), dietary nutrition and mental health are also key factors in maintaining immune system health and combating emerging and sudden outbreaks of infections. As the main dietary nutrients, vitamins are active regulators of the immune response and exert a critical impact on the immunity of the human body. Vitamin deficiency causes increased levels of inflammation and decreased immunity, which usually starts in the oral tissues. Appropriate vitamin supplementation can help the body optimize immune function, enhance oral immunity, and reduce the negative impact of pathogen infection on the human body, which makes it a feasible, effective, and universally applicable anti-infection solution. This review focuses on the immunomodulatory effects of vitamin A, B, C, D, and E and proposes that an omics-based new systemic approach will lead to a breakthrough of the limitations in traditional single-factor single-pathway research and provide the direction for the basic and applied research of vitamin immune regulation and anti-infection in all aspects.
MeSH term(s)	Humans ; Vitamins/therapeutic use ; Vitamins/pharmacology ; Vitamin A/pharmacology ; Immune System/physiology ; Vitamin K/pharmacology ; Inflammation/drug therapy ; Dietary Supplements
Chemical Substances	Vitamins ; Vitamin A (11103-57-4) ; Vitamin K (12001-79-5)
Language	Chinese
Publishing date	2023-01-16
Publishing country	China
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	2106840-9
ISSN	1672-173X
ISSN	1672-173X
DOI	10.12182/20230160107
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Article: Sclerotic Liposarcoma in the Deep Temporal Space of a 7-year-old Child.

Kong, Wei-Li / Li, Wen

Chinese medical journal

2017 Volume 130, Issue 14, Page(s) 1759–1760

MeSH term(s)	Child ; Female ; Humans ; Liposarcoma/metabolism ; Liposarcoma/surgery ; Retroperitoneal Neoplasms/metabolism ; Retroperitoneal Neoplasms/surgery
Language	English
Publishing date	2017-07-03
Publishing country	China
Document type	Case Reports ; Letter
ZDB-ID	127089-8
ISSN	0366-6999 ; 1002-0187
ISSN	0366-6999 ; 1002-0187
DOI	10.4103/0366-6999.209907
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Article ; Online: Lysosome-targetable brightly green fluorescence carbon dots for real-time monitoring in cell and highly efficient removal in environment of hypochlorite.

Zou, Wen-Sheng / Xu, Yu / Li, Weihua / Kong, Wei-Li / Li, Haibin / Qu, Qishu / Wang, Yaqin

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

2022 Volume 281, Page(s) 121591

Abstract: Due to the lacks of lysosome localization group and reaction/interaction site for hypochlorite ( ... ...

Abstract	Due to the lacks of lysosome localization group and reaction/interaction site for hypochlorite (ClO
MeSH term(s)	Carbon ; Fluorescent Dyes ; Hypochlorous Acid ; Lysosomes ; Quantum Dots ; Spectrometry, Fluorescence/methods
Chemical Substances	Fluorescent Dyes ; Hypochlorous Acid (712K4CDC10) ; Carbon (7440-44-0)
Language	English
Publishing date	2022-07-04
Publishing country	England
Document type	Journal Article
ZDB-ID	210413-1
ISSN	1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
ISSN (online)	1873-3557
ISSN	0370-8322 ; 0584-8539 ; 1386-1425
DOI	10.1016/j.saa.2022.121591
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Article ; Online: Branchiogenic carcinoma in the parotid gland.

Zeng, Bin / Li, Wen / Yang, Liu / Kong, Wei-Li

Chinese medical journal

2019 Volume 132, Issue 19, Page(s) 2388–2389

MeSH term(s)	Aged, 80 and over ; Branchioma/pathology ; Humans ; Male ; Parotid Neoplasms/pathology
Language	English
Publishing date	2019-09-30
Publishing country	China
Document type	Case Reports ; Journal Article
ZDB-ID	127089-8
ISSN	2542-5641 ; 0366-6999 ; 1002-0187
ISSN (online)	2542-5641
ISSN	0366-6999 ; 1002-0187
DOI	10.1097/CM9.0000000000000451
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Article ; Online: Dinuclear magnesium, zinc and aluminum complexes supported by bis(iminopyrrolide) ligands: synthesis, structures, and catalysis toward the ring-opening polymerization of ε-caprolactone and rac-lactide.

Kong, Wei-Li / Wang, Zhong-Xia

Dalton transactions (Cambridge, England : 2003)

2014 Volume 43, Issue 24, Page(s) 9126–9135

Abstract: Synthesis and characterization of novel dinuclear magnesium, zinc and aluminum complexes supported by bis(iminopyrrolide) ligands and their catalysis toward the ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) and rac-lactide (rac-LA) were ... ...

Abstract	Synthesis and characterization of novel dinuclear magnesium, zinc and aluminum complexes supported by bis(iminopyrrolide) ligands and their catalysis toward the ring-opening polymerization (ROP) of ε-caprolactone (ε-CL) and rac-lactide (rac-LA) were carried out. The ligand precursors [(5-Bu(t)-2-C4H2NH)CH=N(CH2)2]2NH (H2L(Bu), 1) and [(2-C4H3NH)CH=N(CH2)2]2NH (H2L(H), 2) were prepared by condensation of diethylene triamine with 5-tert-butyl-1H-pyrrole-2-carbaldehyde and 1H-pyrrole-2-carbaldehyde, respectively. Treatment of 1 with 2 equiv. of Bu(n)MgOBn in toluene at 70 °C produced dinuclear magnesium complex [(μ-OBn)2Mg2L(Bu)] (3). Similar treatment of 1 with EtZnOBn generated [(μ-OBn)2Zn2L(Bu)] (4). Reaction of 2 with 2 equiv. of Me2AlOBn in toluene at 70 °C afforded aluminum complex [Me2Al(μ-OBn)2AlL(H)] (5). Complexes 3-5 were characterized by (1)H and (13)C NMR spectroscopy, elemental analyses, and single crystal X-ray diffraction techniques. Each of complexes 3-5 is active for the ROP of ε-CL and rac-LA. Kinetic studies of the polymerization reactions were performed.
MeSH term(s)	Aluminum/chemistry ; Amines/chemistry ; Caproates/chemistry ; Catalysis ; Crystallography, X-Ray ; Dioxanes/chemistry ; Lactones/chemistry ; Ligands ; Magnesium/chemistry ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Polymerization ; Polymers/chemistry ; Probability ; Solvents ; Temperature ; Toluene/chemistry ; X-Ray Diffraction ; Zinc/chemistry
Chemical Substances	Amines ; Caproates ; Dioxanes ; Lactones ; Ligands ; Polymers ; Solvents ; Toluene (3FPU23BG52) ; caprolactone (56RE988L1R) ; dilactide (95-96-5) ; Aluminum (CPD4NFA903) ; Magnesium (I38ZP9992A) ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2014-06-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/c4dt00431k
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Identification of m6a-related signature genes in esophageal squamous cell carcinoma by machine learning method.

Shang, Qi-Xin / Kong, Wei-Li / Huang, Wen-Hua / Xiao, Xin / Hu, Wei-Peng / Yang, Yu-Shang / Zhang, Hanlu / Yang, Lin / Yuan, Yong / Chen, Long-Qi

Frontiers in genetics

2023 Volume 14, Page(s) 1079795

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-01-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2023.1079795
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Article: Effect of circumferential resection margin status on survival and recurrence in esophageal squamous cell carcinoma with neoadjuvant chemoradiotherapy.

Gu, Yi-Min / Yang, Yu-Shang / Kong, Wei-Li / Shang, Qi-Xin / Zhang, Han-Lu / Wang, Wen-Ping / Yuan, Yong / Che, Guo-Wei / Chen, Long-Qi

Frontiers in oncology

2022 Volume 12, Page(s) 965255

Abstract: Background: The aim of this study was to investigate whether circumferential resection margin (CRM) status has an impact on survival and recurrence in esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy.: Methods: We screened ... ...

Abstract	Background: The aim of this study was to investigate whether circumferential resection margin (CRM) status has an impact on survival and recurrence in esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy. Methods: We screened patients with esophageal squamous cell carcinoma who underwent esophagectomy from January 2017 to December 2019. The CRM was reassessed. Patients were grouped into a CRM of 1 mm or less (0 < CRM ≤ 1 mm) and a CRM greater than 1 mm (CRM>1 mm). The impact of CRM on survival was investigated using Kaplan-Meier analysis and Cox regression modeling. The optimal CRM cut point was evaluated using restricted cubic spline curve. Results: A total of 89 patients were enrolled in this study. The CRM status was an independent risk factor for the prognosis (HR: 0.35, 95% CI: 0.16-0.73). Compared with a CRM of 1 mm or less, a CRM greater than 1 mm had better overall survival (HR: 0.35, 95% CI: 0.16-0.73, log-rank Conclusions: A CRM greater than 1 mm had better survival and less recurrence compared to a CRM of 1 mm or less. A more radical resection with adequate CRM could benefit survival in patients with esophageal squamous cell carcinoma after neoadjuvant therapy.
Language	English
Publishing date	2022-09-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2022.965255
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Article ; Online: Synthesis of N,N,O-chelate zinc and aluminum complexes and their catalysis in the ring-opening polymerization of ε-caprolactone and rac-lactide.

Kong, Wei-Li / Chai, Zuo-Yun / Wang, Zhong-Xia

Dalton transactions (Cambridge, England : 2003)

2014 Volume 43, Issue 38, Page(s) 14470–14480

Abstract: Zinc and aluminum complexes supported by N,N,O-chelate ligands were synthesized and characterized. The zinc complexes [Zn(Et){2-{OC(R(1))=CH}-6-(3,5-Me2C3HN2)C5H3N}]2 (R(1) = Ph, 1a; R(1) = Bu(t), 1b) were synthesized by reaction of ligand precursors 2-{ ... ...

Abstract	Zinc and aluminum complexes supported by N,N,O-chelate ligands were synthesized and characterized. The zinc complexes [Zn(Et){2-{OC(R(1))=CH}-6-(3,5-Me2C3HN2)C5H3N}]2 (R(1) = Ph, 1a; R(1) = Bu(t), 1b) were synthesized by reaction of ligand precursors 2-{R(1)C(O)CH2}-6-(3,5-Me2C3HN2)C5H3N (R(1) = Ph, HL(1); R(1) = Bu(t), HL(2)) with ZnEt2. The aluminum complexes [Al(R)2{2-{OC(Ph)=CH}-6-(3,5-Me2C3HN2)C5H3N}] (R = Me, 2a; R = Et, 2b) were synthesized by reaction of HL(1) with AlMe3 or AlEt3. Similar treatment of the ligand precursor 2-{Ph2C(OH)CH2}-6-(3,5-Me2C3HN2)C5H3N (HL(3)) with AlMe3 or AlEt3 afforded aluminum complexes [Al(R)2{2-{OC(Ph)2CH2}-6-(3,5-Me2C3HN2)C5H3N}] (R = Me, 3a; R = Et, 3b). The complexes were characterized by (1)H and (13)C{(1)H} NMR spectroscopy, elemental analyses and single crystal X-ray diffraction (for 1a, 1b, 2b and 3a). All the complexes are active to catalyze the ring-opening polymerization of ε-caprolactone in the presence of BnOH, leading to polycaprolactone with good molecular weight control and relatively narrow molecular weight distribution. The zinc complexes/BnOH showed good catalytic activity for the ring-opening polymerization of rac-lactide, displaying good molecular weight control and very narrow molecular weight distributions. The PLA catalyzed by complex 1a/BnOH showed somewhat hetero-stereoselectivity with Pr up to 0.73 when the polymerization was performed in THF at 0 °C. Complex 1a/BnOH also catalyzed block copolymerization of ε-CL and rac-LA with good molecular weight control of the polymer. Kinetic studies of the polymerization reactions were performed.
MeSH term(s)	Aluminum/chemistry ; Caproates/chemistry ; Catalysis ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Crystallography, X-Ray ; Dioxanes/chemistry ; Lactones/chemistry ; Ligands ; Models, Molecular ; Polymerization ; Zinc/chemistry
Chemical Substances	Caproates ; Coordination Complexes ; Dioxanes ; Lactones ; Ligands ; caprolactone (56RE988L1R) ; dilactide (95-96-5) ; Aluminum (CPD4NFA903) ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2014-10-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/c4dt01364f
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Article ; Online: A composite consisting of bromine-doped carbon dots and ferric ions as a fluorescent probe for determination and intracellular imaging of phosphate.

Zou, Wen-Sheng / Kong, Wei-Li / Zhao, Qin-Chun / Zhang, Jun / Zhao, Xiaoli / Zhao, Donglin / Wang, Ya-Qin

Mikrochimica acta

2019 Volume 186, Issue 8, Page(s) 576

Abstract: A composite probe has been developed for fluorometric determination and imaging of phosphate in real water samples and in cells. The method is based on the use of weakly blue fluorescent bromine-doped carbon dots (C-dots) containing aromatic carbon- ... ...

Abstract	A composite probe has been developed for fluorometric determination and imaging of phosphate in real water samples and in cells. The method is based on the use of weakly blue fluorescent bromine-doped carbon dots (C-dots) containing aromatic carbon-bromine groups and loaded with Fe
MeSH term(s)	Bromine/chemistry ; Carbon/chemistry ; Ferric Compounds/chemistry ; Fluorescent Dyes/chemistry ; Fresh Water/analysis ; HeLa Cells ; Humans ; Ions/chemistry ; Limit of Detection ; Microscopy, Confocal ; Phosphates/analysis ; Quantum Dots/chemistry ; Spectrometry, Fluorescence
Chemical Substances	Ferric Compounds ; Fluorescent Dyes ; Ions ; Phosphates ; Carbon (7440-44-0) ; Bromine (SBV4XY874G)
Language	English
Publishing date	2019-07-25
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	89-9
ISSN	1436-5073 ; 0026-3672
ISSN (online)	1436-5073
ISSN	0026-3672
DOI	10.1007/s00604-019-3700-6
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Article: Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in <i>Staphylococcus aureus</i> from Various Veterinary Hospitals

Chen, Lin / Tang, Zi-Yun / Cui, Shi-Yun / Ma, Zhen-Bao / Deng, Hua / Kong, Wei-Li / Yang, Li-Wen / Lin, Chao / Xiong, Wen-Guang / Zeng, Zhen-Ling

Pathogens. 2020 Apr. 04, v. 9, no. 4

2020

Abstract: ... Staphylococcus aureus ... ( ... S. aureus ... ) is one of the most clinically important zoonotic pathogens, but an understanding of the prevalence, biofilm formulation ability, virulence, and antimicrobial resistance genes of ... S. aureus ... from ... ...

Abstract	Staphylococcus aureus (S. aureus) is one of the most clinically important zoonotic pathogens, but an understanding of the prevalence, biofilm formulation ability, virulence, and antimicrobial resistance genes of S. aureus from veterinary hospitals is lacking. By characterizing S. aureus in different origins of veterinary hospitals in Guangzhou, China, in 2019, we identified with the presence of S. aureus in pets (17.1%), veterinarians (31.7%), airborne dust (19.1%), environmental surfaces (4.3%), and medical device surfaces (10.8%). Multilocus sequence typing (MLST) and Staphylococcus protein A (spa) typing analyses demonstrated methicillin-sensitive S. aureus (MSSA) ST398-t571, MSSA ST188-t189, and methicillin-resistant S. aureus (MRSA) ST59-t437 were the most prevalent lineage. S. aureus with similar pulsed-field gel electrophoresis (PFGE) types distributed widely in different kinds of samples. The crystal violet straining assays revealed 100% (3/3) of MRSA ST59 and 81.8% (9/11) of MSSA ST188 showed strong biofilm formulation ability, whereas other STs (ST1, ST5, ST7, ST15, ST88, ST398, ST3154 and ST5353) showed weak biofilm production ability. Polymerase chain reaction (PCR) confirmed the most prevalent leucocidin, staphylococcal enterotoxins, ica operon, and adhesion genes were lukD-lukE (49.0%), sec-sel (15.7%), icaA-icaB-icaC-icaR (100.0%), and fnbB-cidA-fib-ebps-eno (100.0%), respectively. Our study showed that the isolates with strong biofilm production ability had a higher prevalence in clfA, clfB, fnbA and sdrC genes compared to the isolates with weak biofilm production ability. Furthermore, 2 ST1-MRSA isolates with tst gene and 1 ST88-MSSA isolate with lukS/F-PV gene were detected. In conclusion, the clonal dissemination of S. aureus of different origins in veterinary hospitals may have occurred; the biofilm production capacity of S. aureus is strongly correlated with ST types; some adhesion genes such as clfA, clfB, fnbA, and sdrC may pose an influence on biofilm production ability and the emergence of lukS/F-PV and tst genes in S. aureus from veterinary hospitals should raise our vigilance.
Keywords	antibiotic resistance genes ; assays ; biofilm ; cell adhesion molecules ; dust ; enterotoxins ; gentian violet ; methicillin-resistant Staphylococcus aureus ; multilocus sequence typing ; operon ; pathogens ; pets ; polymerase chain reaction ; prevalence ; pulsed-field gel electrophoresis ; sampling ; surfaces ; veterinarians ; veterinary clinics ; virulence ; China
Language	English
Dates of publication	2020-0404
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
Note	NAL-light
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens9040264
Database	NAL-Catalogue (AGRICOLA)

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