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  1. Article ; Online: CRC COVID

    Kontovounisios, C

    Colorectal Cancer Services during COVID-19 pandemic. Study protocol for service evaluation

    2020  

    Abstract: Introduction COVID-19 has had an impact on the provision of colorectal cancer care. The aim of the CRC COVID study is to describe the changes in colorectal cancer services in the UK and USA in response to the pandemic and to understand the long-term ... ...

    Abstract Introduction COVID-19 has had an impact on the provision of colorectal cancer care. The aim of the CRC COVID study is to describe the changes in colorectal cancer services in the UK and USA in response to the pandemic and to understand the long-term impact. Methods and analysis This study comprises 4 phases. Phase 1 is a survey of colorectal units that aims to evaluate adherences and deviations from the best practice guidelines during the COVID-19 pandemic. Phase 2 is a monthly prospective data collection of service provision that aims to determine the impact of the service modifications on the long-term cancer specific outcomes compared to the national standards. Phase 3 aims to predict costs attributable to the modifications of the CRC services and additional resources required to treat patients whose treatment has been affected by the pandemic. Phase 4 aims to compare the impact of COVID-19 on the NHS and USA model of healthcare in terms of service provision and cost, and to propose a standardised model of delivering colorectal cancer services for future outbreaks.
    Keywords covid19
    Publishing date 2020-07-30
    Publisher Elsevier
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: The Antineoplastic Effect of Heparin on Colorectal Cancer: A Review of the Literature.

    Giannas, Emmanuel / Kontovounisios, Christos

    Journal of clinical medicine

    2023  Volume 12, Issue 22

    Abstract: Heparin and derivatives are commonly used for thrombophylaxis in surgical colorectal cancer (CRC) patients. Recent studies have suggested that, besides its protective effect on the incidence of venous thromboembolism, heparin has an anti-cancer effect. ... ...

    Abstract Heparin and derivatives are commonly used for thrombophylaxis in surgical colorectal cancer (CRC) patients. Recent studies have suggested that, besides its protective effect on the incidence of venous thromboembolism, heparin has an anti-cancer effect. The aim of this review was to explore the literature and report the antineoplastic effect of heparin and derivatives on CRC. MEDLINE and EMBASE databases were searched for relevant articles. Nineteen studies were included (
    Language English
    Publishing date 2023-11-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12227173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Use of Mechanical Bowel Preparation and Oral Antibiotic Prophylaxis in Elective Colorectal Surgery: A Call for Change in Practice.

    Petrou, Nikoletta A / Kontovounisios, Christos

    Cancers

    2022  Volume 14, Issue 23

    Abstract: Elective colorectal surgery is associated with one of the highest rates of surgical site infections (SSIs), which result in prolonged length of stay, morbidity, and mortality for these patients and have a significant financial burden to healthcare ... ...

    Abstract Elective colorectal surgery is associated with one of the highest rates of surgical site infections (SSIs), which result in prolonged length of stay, morbidity, and mortality for these patients and have a significant financial burden to healthcare systems. In an effort to reduce the frequency of SSI rates associated with colorectal surgery, the 2018 World Health Organisation (WHO) guidelines recommend the routine use of mechanical bowel preparation (MBP) and oral antibiotic prophylaxis (OAP) in adult patients undergoing elective colorectal surgery. However, this recommendation remains a topic of debate internationally. The National Institute of Clinical Excellence (NICE) guidelines, last revised in 2019, recommend against the routine use of MBP and do not address the issue of OAP. In this communication, we reviewed the current guidelines and examined the most recent evidence from randomised-control trials (RCTs) and meta-analyses on the effect of MBP and OAP on SSI rates since the 2019 NICE guideline review. This recent evidence clearly demonstrated an SSI-risk-reduction benefit with the additional use of OAP and the combination of MBP and OAP in this group of patients, and we therefore highlight the need for change of the current NICE guidelines.
    Language English
    Publishing date 2022-12-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14235990
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Validation of a Tool-Based Visual Anorectal Examination Advanced Simulator for the Early Detection of Colorectal Cancer.

    Grayson, Niamh / Haghighi Osgouei, Reza / Huang, Renke / Tekkis, Paris / Bello, Fernando / Kontovounisios, Christos

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Rectal examination through proctoscopy or rigid sigmoidoscopy is a common investigation in clinical practice. It is an important diagnostic tool for the workup and management of anorectal pathologies. Performing the examination can be daunting not only ... ...

    Abstract Rectal examination through proctoscopy or rigid sigmoidoscopy is a common investigation in clinical practice. It is an important diagnostic tool for the workup and management of anorectal pathologies. Performing the examination can be daunting not only for patients but also for junior doctors. There are associated risks with the procedure, such as pain, diagnostic failure, and perforation of the bowel. Simulation-based training is recognised as an important adjunct in clinical education. It allows students and doctors to practice skills and techniques at their own pace in a risk-free environment. These skills can then be transferred to and developed further in clinical practice. There is extensive research published regarding the role of simulation-based training in endoscopy, however, we identified no published study regarding simulation-based training in rigid sigmoidoscopy or proctoscopy. This study aims to establish the initial face, content, and construct validity of a tool-based visual anorectal examination advanced simulator model for proctoscopy and rigid sigmoidoscopy. This innovative, highly realistic simulated environment aims to enhance the training of healthcare professionals and improve the efficiency of detecting and diagnosing distal colorectal disease.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051423
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Re-Do Plastic Reconstruction for Locally Advanced and Recurrent Colorectal Cancer Following a beyond Total Mesorectal Excision (TME) Operation-Key Considerations.

    Giannas, Emmanuel / Kavallieros, Konstantinos / Nanidis, Theodoros / Giannas, John / Tekkis, Paris / Kontovounisios, Christos

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Innovation in surgery and pelvic oncology have redefined the boundaries of pelvic exenteration for CRC. However, surgical approaches and outcomes following repeat exenteration and reconstruction are not well described. The resulting defect from a second ... ...

    Abstract Innovation in surgery and pelvic oncology have redefined the boundaries of pelvic exenteration for CRC. However, surgical approaches and outcomes following repeat exenteration and reconstruction are not well described. The resulting defect from a second beyond Total Mesorectal Excision (TME) presents a challenge to the reconstructive surgeon. The aim of this study was to explore reconstructive options for patients undergoing repeat beyond TME for recurrent CRC following previous beyond TME and regional reconstruction. MEDLINE and Embase were searched for relevant articles, yielding 2353 studies. However, following full text review and the application of the inclusion criteria, all the studies were excluded. This study demonstrated the lack of reporting on re-do reconstruction techniques following repeat exenteration for recurrent CRC. Based on this finding, we conducted a point-by-point discussion of certain key aspects that should be taken into consideration when approaching this patient cohort.
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Laparoscopic totally extraperitoneal hernia repair in patients with a history of previous abdominopelvic surgery.

    Hayward, Romilly / Smith, Jacob J / Kontovounisios, Christos / Qiu, Shengyang / Warren, Oliver J

    Updates in surgery

    2024  

    Abstract: A retrospective cohort study of patients undergoing laparoscopic inguinal hernia repair compared short- and long-term outcomes between individuals with or without history of previous abdominopelvic surgery, aiming to determine the feasibility of totally ... ...

    Abstract A retrospective cohort study of patients undergoing laparoscopic inguinal hernia repair compared short- and long-term outcomes between individuals with or without history of previous abdominopelvic surgery, aiming to determine the feasibility of totally extraperitoneal (TEP) repair within this population. All patients who underwent elective TEP inguinal hernia repair by one consultant surgeon across three London hospitals from January 2017 to May 2023 were retrospectively analysed to assess perioperative outcomes. Two hundred sixty-two patients were identified, of whom two hundred forty-three (93%) underwent laparoscopic TEP repair. The most frequent complications were haematoma (6.2%) and seroma (4.1%). Recurrence occurred in four cases (1.6% of operations, 1.1% of hernias). One hundred eighty-four patients (76%) underwent day-case surgery. There were no mesh infections or explanations, vascular or visceral injuries, port-site hernias, damage to testicle, or persisting numbness. There were no requirements for blood transfusion, returns to theatre, or readmissions within 30 days. There was one conversion to open and one death within 60 days of surgery. Eighty-three (34%) had a history of previous AP surgery. There was no significant difference in perioperative outcomes between the AP and non-AP arms. This finding carried true for subgroup analysis of 44 patients whose AP surgical history did not include previous inguinal hernia repair and for those undergoing repair of recurrent hernia. In expert hands, laparoscopic TEP repair is associated with excellent outcomes and low rates of long-term complications, and thus should be considered as standard for patients regardless of a history of AP surgery.
    Language English
    Publishing date 2024-04-23
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-024-01810-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 101: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The role of masterclasses in surgical oncology training: experience from a colorectal cancer surgery masterclass.

    Kontovounisios, Christos

    International journal of colorectal disease

    2015  Volume 31, Issue 5, Page(s) 1065–1066

    MeSH term(s) Colorectal Surgery/education ; Education, Medical, Graduate ; Humans ; Surgeons ; Surgical Oncology/education
    Language English
    Publishing date 2015-09-26
    Publishing country Germany
    Document type Letter
    ZDB-ID 84975-3
    ISSN 1432-1262 ; 0179-1958
    ISSN (online) 1432-1262
    ISSN 0179-1958
    DOI 10.1007/s00384-015-2387-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2121: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: 3D imaging and printing in pelvic colorectal cancer: 'The New Kid on the Block'.

    Kontovounisios, C / Tekkis, P / Bello, F

    Techniques in coloproctology

    2019  Volume 23, Issue 2, Page(s) 171–173

    MeSH term(s) Adult ; Colorectal Neoplasms/diagnostic imaging ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Male ; Models, Anatomic ; Pelvic Neoplasms/diagnostic imaging ; Pelvis/diagnostic imaging ; Printing, Three-Dimensional
    Language English
    Publishing date 2019-01-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-018-1922-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5842: Show issues Location:
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  9. Article ; Online: Is it the surgeon or the technology performing the operation?

    El-Bahnasawi, M / Tekkis, P / Kontovounisios, C

    Techniques in coloproctology

    2019  Volume 23, Issue 9, Page(s) 933–934

    MeSH term(s) Biomedical Technology/trends ; Clinical Competence ; Colorectal Surgery/trends ; Humans ; Surgeons/trends
    Language English
    Publishing date 2019-08-20
    Publishing country Italy
    Document type Letter
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-019-02063-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5842: Show issues Location:
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  10. Article ; Online: Rectal 3D MRI modelling for benign and malignant disease.

    Przedlacka, A / Cox, S / Tekkis, P / Bello, F / Kontovounisios, C

    The British journal of surgery

    2020  Volume 107, Issue 11, Page(s) e561–e562

    MeSH term(s) Humans ; Imaging, Three-Dimensional/methods ; Magnetic Resonance Imaging/methods ; Models, Anatomic ; Pelvis/diagnostic imaging ; Pelvis/pathology ; Rectal Diseases/diagnostic imaging ; Rectal Diseases/pathology ; Rectal Diseases/surgery ; Rectum/diagnostic imaging ; Rectum/pathology
    Language English
    Publishing date 2020-08-25
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11858
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