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  1. Book ; Thesis: Immunhistochemischer Nachweis der Domänen III und V von Perlecan im menschlichen Embryo

    Korn, Alexandra

    2005  

    Author's details vorgelegt von Alexandra Korn
    Language German
    Size 71 Bl., Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Göttingen, Univ.. Diss., 2005
    HBZ-ID HT014887720
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2003 MB 2209 order for loan Magazin

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  2. Book ; Thesis: Inactivation of human tumour cells by hydrostatic pressure

    Korn, Andreas

    2007  

    Author's details vorgelegt von Andreas Korn
    Subject code 616.99
    Language English
    Size 33 Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Erlangen, Nürnberg, Univ., Diss., 2007
    Note Enth. 3 Sonderabdr. aus verschiedenen Zeitschr.
    HBZ-ID HT015331771
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2007 E 2136 order for loan Magazin

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  3. Article: Das Infraspinatus-Syndrom

    Korn, Andreas

    Naturheilpraxis

    2019  Volume 72, Issue 7, Page(s) 17

    Language German
    Document type Article
    ZDB-ID 2836713-3
    ISSN 0177-6754 ; 2366-4576
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1101: Show issues Location:
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  4. Article ; Online: Conformation of Pyroglutamated Amyloid β (3-40) and (11-40) Fibrils - Extended or Hairpin?

    Scheidt, Holger A / Korn, Alexander / Schwarze, Benedikt / Krueger, Martin / Huster, Daniel

    The journal of physical chemistry. B

    2024  Volume 128, Issue 7, Page(s) 1647–1655

    Abstract: Amyloid β (Aβ) is a hallmark protein of Alzheimer's disease. One physiologically important Aβ variant is formed by initial N-terminal truncation at a glutamic acid position (either ... ...

    Abstract Amyloid β (Aβ) is a hallmark protein of Alzheimer's disease. One physiologically important Aβ variant is formed by initial N-terminal truncation at a glutamic acid position (either E
    MeSH term(s) Humans ; Amyloid beta-Peptides/chemistry ; Alzheimer Disease/metabolism ; Molecular Conformation ; Molecular Structure ; Magnetic Resonance Spectroscopy ; Amyloid ; Peptide Fragments/chemistry
    Chemical Substances Amyloid beta-Peptides ; Amyloid ; Peptide Fragments
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c07285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [COMPARISON OF HIGH GAMMA ELECTROCORTICOGRAPHY AND DIRECT CORTICAL STIMULATION MAPPING OF CORTICAL FUNCTION IN AWAKE CRANIOTOMY: INITIAL EXPERIENCE].

    Shahar, Tal / Gonen, Lior / Michaeli, Avner / Korn, Akiva / Margalit, Nevo

    Harefuah

    2023  Volume 162, Issue 4, Page(s) 221–227

    Abstract: Introduction: The use of intraoperative electrical cortical stimulation (ECS) to map function is the standard of care in modern neurosurgery. Recently, high gamma electrocorticography (hgECOG) mapping has had encouraging results. In this study we aim to ...

    Abstract Introduction: The use of intraoperative electrical cortical stimulation (ECS) to map function is the standard of care in modern neurosurgery. Recently, high gamma electrocorticography (hgECOG) mapping has had encouraging results. In this study we aim to compare hgECOG and fMRI with ECS for motor and language mapping.
    Methods: We retrospectively evaluated medical records of patients who underwent awake surgery for tumor resection between January 2018 and December 2021. The first 10 consecutive patients who underwent ECS and hgECOG for mapping of motor and language functions were defined as the study group. Pre- and intra-operative imaging and electrophysiology data were used for analysis.
    Results: ECS and hgECOG motor mapping demonstrated functional motor areas in 71.4% and 85.7% of patients, respectively. All motor areas identified with ECS were also demonstrated using hgECOG. In 2 patients, hgECOG-based mapping demonstrated motor areas not demonstrated with ECS but present in preoperative fMRI imaging. Of the 15 hgECOG tasks performed for language mapping, the findings of 6 (40%) were in accordance with the ECS mapping. Two (13.3%), showed language areas that were demonstrated using ECS and in addition, showed areas that were not. Four mappings (26.7%) showed language areas that were not demonstrated using ECS. In 3 mappings (20%), the functional areas identified by ECS were not demonstrated by hgECOG.
    Conclusions: Intraoperative hgECOG for mapping of motor and language functions provide a fast and reliable method without the risk of stimulation-induced seizures. Further studies are needed to assess functional outcome of patients undergoing hgECOG-guided tumor resection.
    MeSH term(s) Humans ; Electrocorticography ; Brain Neoplasms/surgery ; Wakefulness ; Retrospective Studies ; Brain Mapping/methods ; Craniotomy/methods ; Magnetic Resonance Imaging/methods
    Language Hebrew
    Publishing date 2023-04-29
    Publishing country Israel
    Document type English Abstract ; Journal Article
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 291: Show issues Location:
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  6. Article: Atomic diffusion and mixing in old stars - VIII. Chemical abundance variations in the globular cluster M4 (NGC 6121).

    Nordlander, T / Gruyters, P / Richard, O / Korn, A J

    Monthly notices of the Royal Astronomical Society

    2023  Volume 527, Issue 4, Page(s) 12120–12139

    Abstract: Variations in chemical abundances with evolutionary phase have been identified among stars in globular and open clusters with a wide range of metallicities. In the metal-poor clusters, these variations compare well with predictions from stellar structure ...

    Abstract Variations in chemical abundances with evolutionary phase have been identified among stars in globular and open clusters with a wide range of metallicities. In the metal-poor clusters, these variations compare well with predictions from stellar structure and evolution models considering the internal diffusive motions of atoms and ions, collectively known as atomic diffusion, when moderated by an additional mixing process with a fine-tuned efficiency. We present here an investigation of these effects in the Galactic globular cluster NGC 6121 (M4) ([Fe/H] = -1.13) through a detailed chemical abundance analysis of 86 stars using high-resolution ESO Very Large Telescope (VLT) Fibre Large Array Multi Element Spectrograph (FLAMES) spectroscopy. The stars range from the main-sequence turnoff point (TOP) to the red giant branch (RGB) just above the bump. We identify C-N-O and Mg-Al-Si abundance anticorrelations, and confirm the presence of a bimodal population differing by 1 dex in nitrogen abundance. The composition of the second-generation stars imply pollution from both massive (20-40 [Formula: see text]) and asymptotic giant branch stars. We find evolutionary variations in chemical abundances between the TOP and RGB, which are robust to uncertainties in stellar parameters and modelling assumptions. The variations are weak, but match predictions well when employing efficient additional mixing. Without correcting for Galactic production of lithium, we derive an initial lithium abundance 2.63 ± 0.10, which is marginally lower than the predicted primordial big-bang nucleosynthesis value.
    Language English
    Publishing date 2023-12-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 207232-4
    ISSN 0035-8711
    ISSN 0035-8711
    DOI 10.1093/mnras/stad3973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  7. Book ; Thesis: Monoklonale Antikörper zur Untersuchung der Wechselwirkung von Lipopolysaccharid mit Makrophagen

    Korn, Alexander

    1992  

    Author's details vorgelegt von Alexander Korn
    Language German
    Size V, 156 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Darmstadt, Techn. Hochsch., Diss., 1993
    Note 2 Mikrofiches
    HBZ-ID HT006503277
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1995 MB 159 order for loan Magazin

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  8. Article: Integrated safety system technology is here.

    Korn, Alan

    Occupational health & safety (Waco, Tex.)

    2013  Volume 82, Issue 3, Page(s) 41–42

    MeSH term(s) Accidents, Traffic/prevention & control ; Humans ; Motor Vehicles/standards ; Occupational Health ; Organizational Culture ; Safety Management/methods
    Language English
    Publishing date 2013-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752994-6
    ISSN 0362-4064
    ISSN 0362-4064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Un I Zs.378: Show issues Location:
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  9. Article ; Online: Post-laminectomy Dorsal Cord Migration Resulting in Immediate Neurologic Deterioration during Ventral Meningioma Resection: Proposed Mechanism of Injury and Prevention Technique.

    Harel, Ran / Kimchi, Gil / Perry, Avital / Korn, Akiva / Knoller, Nachshon

    Journal of neurological surgery. Part A, Central European neurosurgery

    2022  Volume 84, Issue 5, Page(s) 498–505

    Abstract: Background:  Ventral thoracic meningiomas may pose a technical challenge owing to a limited surgical corridor and the presence of long-standing ventral cord compression. Unopposed dorsal spinal cord migration may occur following a laminectomy resulting ... ...

    Abstract Background:  Ventral thoracic meningiomas may pose a technical challenge owing to a limited surgical corridor and the presence of long-standing ventral cord compression. Unopposed dorsal spinal cord migration may occur following a laminectomy resulting in immediate neurologic injury. We discuss the possible mechanism underlying such a phenomenon, suggesting alternative approach to prevent neurologic injury.
    Methods:  Two patients operated on for ventral thoracic meningioma and sustained neurologic compromise were retrospectively evaluated. Image editing software was used for 3D modeling to simulate the possible underlying mechanism of injury. Cases where ventral thoracic meningiomas were approached via unilateral hemilaminectomy, performed in 2020, were retrospectively analyzed and compared with the laminectomy approach cohort.
    Results:  Two patients sustained postoperative neurologic function decline following resection of ventral thoracic meningioma via the laminectomy approach. Both exhibited permanent abolishment of transcranial motor evoked potentials (MEPs) following laminectomy. Based on the extrapolated 3D models for these two cases, dorsal cord migration was postulated as the cause for the acute neurologic compromise.
    Conclusion:  Laminectomy for resection of thoracic ventral meningioma may lead in some cases to dorsal cord migration resulting in grave neurologic deterioration. Unilateral approach to these tumors restricts the dorsal migration and may mitigate neurologic outcomes.
    MeSH term(s) Humans ; Meningioma/surgery ; Laminectomy/adverse effects ; Laminectomy/methods ; Retrospective Studies ; Meningeal Neoplasms/surgery ; Magnetic Resonance Imaging
    Language English
    Publishing date 2022-04-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2651663-9
    ISSN 2193-6323 ; 2193-6315
    ISSN (online) 2193-6323
    ISSN 2193-6315
    DOI 10.1055/a-1832-3393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [INTRAOPERATIVE ELECTROPHYSIOLOGY MAPPING OF CORTICAL FUNCTION: A BRIEF HISTORY AND EVOLVING ALTERNATIVE].

    Shahar, Tal / Gonen, Lior / Michaeli, Avner / Korn, Akiva / Margalit, Nevo

    Harefuah

    2022  Volume 162, Issue 4, Page(s) 236–242

    Abstract: Introduction: Multiple studies have demonstrated that the improved extent of resection for patients with glioma is associated with improved survival. The use of intraoperative electrophysiology cortical mapping to demonstrate function became a standard ... ...

    Abstract Introduction: Multiple studies have demonstrated that the improved extent of resection for patients with glioma is associated with improved survival. The use of intraoperative electrophysiology cortical mapping to demonstrate function became a standard of care in modern neurosurgery and an indispensable tool to achieve the goal of maximal safe resection in tumor surgery. In this study, we review the brief history of intraoperative electrophysiology cortical mapping from the first cortical mapping study back in 1870 to the innovative tool of broad gamma cortical mapping used today.
    MeSH term(s) Humans ; Brain Neoplasms/surgery ; Brain Mapping ; Glioma/pathology ; Glioma/surgery ; Neurosurgical Procedures ; Electrophysiology
    Language Hebrew
    Publishing date 2022-01-21
    Publishing country Israel
    Document type Review ; English Abstract ; Journal Article
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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