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Article ; Online: Skew Constacyclic Codes over a Non-Chain Ring.

Köroğlu, Mehmet Emin / Sarı, Mustafa

2023 Volume 25, Issue 3

Abstract: In this paper, we investigate the algebraic structure of the non-local ring Rq=Fq[v]/⟨v2+1⟩ and identify the automorphisms of this ring to study the algebraic structure of the skew constacyclic codes and their duals over this ring. Furthermore, we give a ...

Abstract	In this paper, we investigate the algebraic structure of the non-local ring Rq=Fq[v]/⟨v2+1⟩ and identify the automorphisms of this ring to study the algebraic structure of the skew constacyclic codes and their duals over this ring. Furthermore, we give a necessary and sufficient condition for the skew constacyclic codes over Rq to be linear complementary dual (LCD). We present some examples of Euclidean LCD codes over Rq and tabulate the parameters of Euclidean LCD codes over finite fields as the Φ-images of these codes over Rq, which are almost maximum distance separable (MDS) and near MDS. Eventually, by making use of Hermitian linear complementary duals of skew constacyclic codes over Rq and the map Φ, we give a class of entanglement-assisted quantum error correcting codes (EAQECCs) with maximal entanglement and tabulate parameters of some EAQECCs with maximal entanglement over finite fields.
Language	English
Publishing date	2023-03-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2014734-X
ISSN	1099-4300 ; 1099-4300
ISSN (online)	1099-4300
ISSN	1099-4300
DOI	10.3390/e25030525
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Article ; Online: Can quantitative surface antigen levels and systemic immune-inflammation index be predictive as a new indicator for the initiation of treatment in chronic hepatitis b?

Koroglu, Mehmet / Ayvaz, Muhammed Ali / Bakan, Suat Baran / Sirin, Abdullatif / Akyuz, Umit

European journal of gastroenterology & hepatology

2024 Volume 36, Issue 4, Page(s) 489–497

Abstract: Objectives: The natural history of chronic HBV infection (CHB) is generally divided into four phases: HBeAg-positive chronic HBV infection (EPCI) and -hepatitis (EPCH), HBeAg-negative chronic HBV infection (ENCI) and -hepatitis (ENCH). This study aimed ... ...

Abstract	Objectives: The natural history of chronic HBV infection (CHB) is generally divided into four phases: HBeAg-positive chronic HBV infection (EPCI) and -hepatitis (EPCH), HBeAg-negative chronic HBV infection (ENCI) and -hepatitis (ENCH). This study aimed to investigate changes in serum quantitative surface antigen (qHBsAg), systemic immune-inflammation index (SII) and systemic inflammatory response index (SIRI) in a large number of CHB patients. Method: Three hundred seventy-two CHB patients who underwent liver biopsy between January 2015 and February 2020 were evaluated. Results: The SII-values were strongly significant between EPCI-EPCH ( P = 0.002), however, there was significant difference between ENCI-ENCH ( P = 0.025). Considering the SIRI results, there was a significant difference between both EPCI-EPCH ( P = 0.009) and ENCI-ENCH ( P = 0.118). In HBeAg-positive patients HBV-DNA, qHBsAg, and SII were found to be predictive ( P = 0.029, P = 0.039, P = 0.027, respectively) while in HBeAg-negative patients, age, AST, HBV-DNA, qHBsAg, SII, and SIRI were found to be predictive ( P = 0.047, P = 0.084, P = <0.001, P = 0.001, P = 0.012, P = 0.002, respectively). In EPCH phase, whereby accuracy rate results of HBV-DNA, qHBsAg, and SII were 75.3%, 73.4%, and 60.4%, respectively, while in the ENCH phase the accuracy rates of age, AST, HBV-DNA, qHBsAg, SII, and SIRI values were 57.8%, 65.6%, 68.3%, 63.8%, 57.3% and 53.2%, respectively. Conclusion: HBV-DNA, qHBsAg, and SII are predictive in EPCH patients. Age, AST, HBV-DNA, qHBsAg, SII and SIRI are all predictive in ENCH patients. In patients with CHB, we recommend using SII to distinguish between EPCI-EPCH and ENCI-ENCH. Based on its sensitivity and features, we believe that qHBsAg and SII are suitable measuring instruments in discrimination both of EPCI-EPCH and ENCI-ENCH.
MeSH term(s)	Humans ; Hepatitis B, Chronic/diagnosis ; Hepatitis B, Chronic/drug therapy ; Hepatitis B virus/genetics ; Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Antigens, Surface ; DNA, Viral ; Inflammation
Chemical Substances	Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Antigens, Surface ; DNA, Viral
Language	English
Publishing date	2024-02-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1034239-4
ISSN	1473-5687 ; 0954-691X
ISSN (online)	1473-5687
ISSN	0954-691X
DOI	10.1097/MEG.0000000000002737
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Article ; Online: Investigation of in vitro efficacy of quercetin-meropenem combination in carbapenemase-producing Klebsiella pneumoniae isolates.

Aydemir, Özlem / Ormanoğlu, Gökçen / Ayhancı, Tuğba / Zengin, Mustafa / Köroğlu, Mehmet

Journal of infection in developing countries

2023 Volume 17, Issue 9, Page(s) 1325–1329

Abstract: Introduction: In recent years, the rapid spread of carbapenem-resistant K. pneumoniae, their higher mortality rates, and limited treatment alternatives cause difficulties in the treatment of these infections. New treatment alternatives are needed to ... ...

Abstract	Introduction: In recent years, the rapid spread of carbapenem-resistant K. pneumoniae, their higher mortality rates, and limited treatment alternatives cause difficulties in the treatment of these infections. New treatment alternatives are needed to cope with resistant strains. In recent years, natural products such as Quercetin have started to be preferred in combination studies due to their antimicrobial effects and low side-effect profiles. The aim of this study was to investigate the in vitro efficacy of the combination of Quercetin and Meropenem on carbapenemase-producing (blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP), carbapenem-resistant K.pneumoniae isolates using the checkerboard method. Methodology: Thirty Carbapenem-resistant K.pneumoniae strains in the culture collection of our laboratory were included in our study. Carbapenemase genes were determined using the Xpert® Carba-R (Cepheid, USA). Synergism with meropenem was assessed by checkerboard analysis, followed by FIC index, and combination index calculation. Results: Twenty (66.6%) strains had OXA-48, 6 (20%) NDM, 1 (3.3%) KPC, 1 (3.3%) OXA-48+NDM genes, and 2 strains (6.6%) gene could not be detected. In the Quercetin and Meropenem combination study, synergy was found in 24 (80%) of the strains; an additive effect was found in 5 (16.6%) and an antagonist effect in 1 (3.3%). In 19 (63.3%) of the strains, meropenem MIC values were below the sensitive limit (MIC ≤ 2 μg/mL). Conclusions: Although the combination of quercetin and meropenem has a high synergistic effect in carbapenem-resistant K. pneumoniae isolates, it seems that the carbapenemase species affects this situation. however, more work is needed on this subject.
MeSH term(s)	Humans ; Meropenem/pharmacology ; Anti-Bacterial Agents/pharmacology ; Klebsiella pneumoniae/genetics ; Quercetin/pharmacology ; Bacterial Proteins/genetics ; beta-Lactamases/genetics ; Carbapenems/pharmacology ; Carbapenem-Resistant Enterobacteriaceae/genetics ; Microbial Sensitivity Tests ; Klebsiella Infections
Chemical Substances	Meropenem (FV9J3JU8B1) ; carbapenemase (EC 3.5.2.6) ; Anti-Bacterial Agents ; Quercetin (9IKM0I5T1E) ; Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6) ; Carbapenems
Language	English
Publishing date	2023-09-30
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.17635
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Article: Major and minor subgroup profile of blood in patients receiving multiple transfusions and donors.

Orhan, Mehmet Fatih / Adigül, Merve Pilavci / Altindiş, Mustafa / Köroğlu, Mehmet

Asian journal of transfusion science

2022 Volume 16, Issue 2, Page(s) 219–223

Abstract: Objective: It was aimed to profile the blood subgroups of our region and to reveal the prevalence of auto/alloimmune sensitization in patients who had to undergo multiple erythrocyte transfusions and to establish the sensitization profile by screening ... ...

Abstract	Objective: It was aimed to profile the blood subgroups of our region and to reveal the prevalence of auto/alloimmune sensitization in patients who had to undergo multiple erythrocyte transfusions and to establish the sensitization profile by screening major and minor subgroups. Materials and methods: In this study, the distribution of ABO and Rh system major subgroups was studied in 100 donor blood. As the patient group, 50 patients who received three or more red blood cell transfusions were included. In addition to this group, Kell, Lewis, Duffy blood group systems were studied. Results: According to the ABO system, 35% of the donors were in O, 33% in A, 17% in AB, and 15% in B. According to the Rh system, 75% is Dvi positive. Rh system is 99% e positive and 33% E positive in major subgroups and Kell1 positivity is 8%. In the patient group, 22% D(-) was determined compared to Rh blood group. Among the major subgroups of Rh, C was 68%, E was 14%, c was 76%, and e positivity was found to be 100%. The Kell1 negativity rate is 96%. The highest negativity was found in 86% Lea antigen in Lewis system, in 36% S antigen in MNS system, 34% Fyb antigen in Duffy system, and 24% Jka antigen in Kidd system. When inappropriate blood is given for any antigen, a double population is formed. The double negativities we detected in our study occurred as follows according to blood group systems: E 18%, C 12%, c 8%, Cw 2%, Kell 1 2%, M 8%, N 4%, S 18%, s 6%, Fya 8%, Jka 6%, Jkb 22%. Indirect Agglutination Test (IAT) was negative in all patients. Conclusion: IAT negativity in all patient groups suggests that we do not develop alloimmunization, but the high rates of double population suggest a high risk of alloimmunization.
Language	English
Publishing date	2022-11-12
Publishing country	India
Document type	Journal Article
ZDB-ID	2267310-6
ISSN	1998-3565 ; 0973-6247
ISSN (online)	1998-3565
ISSN	0973-6247
DOI	10.4103/ajts.ajts_17_21
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Article ; Online: Determination of antibiotic susceptibility of bacteria by flow cytometric method.

Hatipoglu, Huseyin / Erman, Gulay / Toptan, Hande / Koroglu, Mehmet / Altindis, Mustafa

World journal of microbiology & biotechnology

2022 Volume 38, Issue 9, Page(s) 151

Abstract: In this study, it was aimed to determine the antibiotic susceptibility of bacterial strains by using flow cytometry method by comparing them with current standardized methods. Eleven clinical isolates and 6 standard bacterial strains were included in the ...

Abstract	In this study, it was aimed to determine the antibiotic susceptibility of bacterial strains by using flow cytometry method by comparing them with current standardized methods. Eleven clinical isolates and 6 standard bacterial strains were included in the study. MIC values were determined by broth microdilution method (BMD), VITEK 2® automated system and flow cytometric method (FCM). FCM was performed with the Accuri C6 flow cytometer. For all strains except P. aeuruginosa ATCC 27853 [BMD-FCM:r = 0.557(p = 0.048); VITEK 2-FCM:r = 0.529(p = 0.063)], E. faecalis ATCC 29212 [BMD-FCM:r = 0.393(p = 0.295); BMD-VITEK 2:r = 0.393(p = 0.295)], and vancomycin-resistant E. faecium clinical isolate [BMD-FCM:r = 0.452(p = 0.063)] r values were in the range of 0.802-0.969 for BMD-FCM (p < 0.001), 0.655-0.941 for BMD-VITEK 2 (p < 0.005) and 0.667-0.953 for FCM-VITEK 2 (p < 0.005). Correlation values of antibiotic susceptibility test results between three methods for Gram-negative bacteria were found as follows; r = 0.927(p < 0.001) for BMD-FCM, r = 0.851(p < 0.001) for BMD-VITEK 2, r = 0.807(p < 0.001) for VITEK 2-FCM. Correlation values were found as follows for Gram positive bacteria; r = 0.848(p < 0.001) for BMD-FCM, r = 0.877(p < 0.001) for BMD-VITEK 2, r = 0.800(p < 0.001) for VITEK 2-FCM. When all bacteria included in the study were evaluated as a total; it was r = 0.911(p < 0.001) for BMD-FCM, r = 0.888(p < 0.001) for BMD-VITEK 2, r = 0.835(p < 0.001) for VITEK 2-FCM. The methicillin resistance of the clinical methicillin resistant S. aureus isolate could not be detected by FCM. It was determined that there was a high level of correlation between methods. FCM shortens the duration of antibiotic susceptibility tests by 12-14 h and gives results within the same day. However, it has not been standardized to be widely used in microbiology laboratories and experienced personnel are needed for its implementation.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Flow Cytometry ; Gram-Negative Bacteria ; Methicillin-Resistant Staphylococcus aureus ; Microbial Sensitivity Tests
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-07-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1499109-3
ISSN	1573-0972 ; 0959-3993
ISSN (online)	1573-0972
ISSN	0959-3993
DOI	10.1007/s11274-022-03332-2
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Book ; Online: New entanglement-assisted MDS quantum codes from constacyclic codes

Koroglu, Mehmet E.

2018

Abstract: Construction of good quantum codes via classical codes is an important task for quantum information and quantum computing. In this work, by virtue of a decomposition of the defining set of constacyclic codes we have constructed eight new classes of ... ...

Abstract	Construction of good quantum codes via classical codes is an important task for quantum information and quantum computing. In this work, by virtue of a decomposition of the defining set of constacyclic codes we have constructed eight new classes of entanglement-assisted quantum maximum distance separable codes.
Keywords	Computer Science - Information Theory
Publishing date	2018-10-03
Publishing country	us
Document type	Book ; Online
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Article: Determination of antibiotic susceptibility of bacteria by flow cytometric method

Hatipoglu, Huseyin / Erman, Gulay / Toptan, Hande / Koroglu, Mehmet / Altindis, Mustafa

World journal of microbiology & biotechnology. 2022 Sept., v. 38, no. 9

2022

Abstract	In this study, it was aimed to determine the antibiotic susceptibility of bacterial strains by using flow cytometry method by comparing them with current standardized methods. Eleven clinical isolates and 6 standard bacterial strains were included in the study. MIC values were determined by broth microdilution method (BMD), VITEK 2® automated system and flow cytometric method (FCM). FCM was performed with the Accuri C6 flow cytometer. For all strains except P. aeuruginosa ATCC 27853 [BMD-FCM:r = 0.557(p = 0.048); VITEK 2-FCM:r = 0.529(p = 0.063)], E. faecalis ATCC 29212 [BMD-FCM:r = 0.393(p = 0.295); BMD-VITEK 2:r = 0.393(p = 0.295)], and vancomycin-resistant E. faecium clinical isolate [BMD-FCM:r = 0.452(p = 0.063)] r values were in the range of 0.802–0.969 for BMD-FCM (p < 0.001), 0.655–0.941 for BMD-VITEK 2 (p < 0.005) and 0.667–0.953 for FCM-VITEK 2 (p < 0.005). Correlation values of antibiotic susceptibility test results between three methods for Gram-negative bacteria were found as follows; r = 0.927(p < 0.001) for BMD-FCM, r = 0.851(p < 0.001) for BMD-VITEK 2, r = 0.807(p < 0.001) for VITEK 2-FCM. Correlation values were found as follows for Gram positive bacteria; r = 0.848(p < 0.001) for BMD-FCM, r = 0.877(p < 0.001) for BMD-VITEK 2, r = 0.800(p < 0.001) for VITEK 2-FCM. When all bacteria included in the study were evaluated as a total; it was r = 0.911(p < 0.001) for BMD-FCM, r = 0.888(p < 0.001) for BMD-VITEK 2, r = 0.835(p < 0.001) for VITEK 2-FCM. The methicillin resistance of the clinical methicillin resistant S. aureus isolate could not be detected by FCM. It was determined that there was a high level of correlation between methods. FCM shortens the duration of antibiotic susceptibility tests by 12–14 h and gives results within the same day. However, it has not been standardized to be widely used in microbiology laboratories and experienced personnel are needed for its implementation.
Keywords	antibiotic resistance ; biotechnology ; flow cytometry ; human resources ; methicillin ; methicillin-resistant Staphylococcus aureus ; minimum inhibitory concentration
Language	English
Dates of publication	2022-09
Size	p. 151.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1499109-3
ISSN	1573-0972 ; 0959-3993
ISSN (online)	1573-0972
ISSN	0959-3993
DOI	10.1007/s11274-022-03332-2
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Investigation of the

Kilic, Umit / Koroglu, Mehmet / Olmez, Mehmet / Altindis, Mustafa

Microbial drug resistance (Larchmont, N.Y.)

2020

Abstract: This study aimed at investigating ... ...

Abstract	This study aimed at investigating the
Language	English
Publishing date	2020-05-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1290490-9
ISSN	1931-8448 ; 1076-6294
ISSN (online)	1931-8448
ISSN	1076-6294
DOI	10.1089/mdr.2019.0498
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Article ; Online: Covid-19

ECE, Gülfem / KÖROĞLU, Mehmet

70-75 ; 2587-1641 ; Journal of Biotechnology and Strategic Health Research

Örnek Alinmasi, Taşinmasi ve Saklanmasi ; Covid-19: Sampling, Transport and Storage

2020

Abstract: Covid-19 tanısında şüpheli hasta tanımına uyan hasta örneklerinin doğru bir şekilde alınması ve transportu son derece önemlidir. Bu amaçla Dünya Sağlık Örgütünün yayınladığı enfeksiyon önleme ve kontrol klavuzlarına uyumlu rehberler geliştirilmiştir. Bu ... ...

Abstract	Covid-19 tanısında şüpheli hasta tanımına uyan hasta örneklerinin doğru bir şekilde alınması ve transportu son derece önemlidir. Bu amaçla Dünya Sağlık Örgütünün yayınladığı enfeksiyon önleme ve kontrol klavuzlarına uyumlu rehberler geliştirilmiştir. Bu bölümde Covid-19 örnek alımı, yöntemleri, zamanlaması ve transferine yönelik uygulamalar güncel rehberler eşliğinde paylaşılacaktır. Accurate collection and transportation of patient samples that meet the definition of suspicious patients are extremely important in the diagnosis of Covid-19. For this purpose, guidelines compatible with the infection prevention and control guidelines published by the World Health Organization have been developed. In this section, applications for Covid-19 sampling, methods, timing and transfer will be shared with current guides.
Keywords	Covid-19,örnek alma ; Covid-19,clinical sampling ; covid19
Language	Turkish
Publishing date	2020-04-30T00:00:00Z
Publisher	Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği
Publishing country	tr
Document type	Article ; Online
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Article ; Online: SARS-CoV-2 ; Enviromental Features of the Virus ; SARS-CoV-2; Virüsün Çevresel Özellikleri

ÖZÖZEN ŞAHİN, Elif / KÖROĞLU, Mehmet

55-64 ; 2587-1641 ; Journal of Biotechnology and Strategic Health Research

2020

Abstract: In order to find a solution to COVID-19 disease, which is a priority to the whole world, Sars CoV-2 virus is tried to be investigated in every aspect. Sars CoV-2 virus, which is the cause of covid-19 disease, tries to investigate in all points. No drugs ... ...

Abstract	In order to find a solution to COVID-19 disease, which is a priority to the whole world, Sars CoV-2 virus is tried to be investigated in every aspect. Sars CoV-2 virus, which is the cause of covid-19 disease, tries to investigate in all points. No drugs and vaccines have been found yet. It is therefore important to prevent further spread of this highly infectious virus. The contamination occurs from person to person and from contaminated surfaces. For this reason, it is an important issue to know how long the virus can survive in different environments. Because; necessary hygiene, disinfection and sterilization measures are evaluated by taking this information into consideration. These aspects of the virus are addressed in this review article and current information on this subject is tried to be presented to the reader. Tüm Dünya’nın gündeminde olan COVID-19 hastalığına çözüm bulmak adına hastalığının etkeni Sars CoV-2 virüsü her yönüyle araştırılmaya çalışılmaktadır. Henüz bir ilaç ve aşı bulunamadığından oldukça bulaşıcı olan bu virüsün daha fazla yayılmasını önlemek önemlidir. Bulaş insandan insana ve kontamine yüzeylerden olmaktadır. Bu nedenle virüsün hangi çevresel ortamlarda ne kadar süre ile canlı kalabildiği bilinmesi gereken önemli bir konudur. Çünkü gerekli hijyen, dezenfeksiyon ve sterilizasyon önlemleri bu bilgiler ışığında şekillenmektedir. Virüs, bu yönleri bu derleme yazısında ele alınmış ve bu konudaki güncel bilgiler okuyucuya sunulmaya çalışılmıştır.
Keywords	Sars CoV-2,COVID-19,contaminate,surface,environmental feature ; Sars-CoV-2,COVID-19,bulaş,yüzey,çevresel özellikler ; covid19
Language	Turkish
Publishing date	2020-04-30T00:00:00Z
Publisher	Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği
Publishing country	tr
Document type	Article ; Online
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