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  1. Article: Cutaneous anthrax in an unusual location: case report.

    Sari, Tugba / Koruk, Suda Tekin

    Le infezioni in medicina

    2015  Volume 23, Issue 4, Page(s) 370–373

    Abstract: Cutaneous anthrax is well known, unlike anthrax of the lumbar region, which is not reported elsewhere. We present a case of anthrax of the lumbar region in a 50-year-old man. The infection was characterised by a wide, black eschar and oedema on an ... ...

    Abstract Cutaneous anthrax is well known, unlike anthrax of the lumbar region, which is not reported elsewhere. We present a case of anthrax of the lumbar region in a 50-year-old man. The infection was characterised by a wide, black eschar and oedema on an erythematous ground. After isolation of the Gram-positive bacilli from the skin lesions, prompt antibiotic treatment (intravenous sulbactam-ampicillin 1.5 g every six hours) was initiated. Following eradication of the bacilli after 14 days of antibiotic treatment, a split-thickness skin graft was applied. A diagnosis of anthrax depends on clinical suspicion. Early diagnosis, antibiotic and surgical treatment can facilitate the treatment and prevent development of complications.
    MeSH term(s) Ampicillin/administration & dosage ; Anthrax/drug therapy ; Anthrax/pathology ; Anti-Bacterial Agents/therapeutic use ; Drug Therapy, Combination ; Humans ; Infusion Pumps ; Lumbosacral Region/pathology ; Male ; Middle Aged ; Skin Diseases, Bacterial/drug therapy ; Skin Diseases, Bacterial/pathology ; Sulbactam/administration & dosage ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents ; Ampicillin (7C782967RD) ; Sulbactam (S4TF6I2330)
    Language English
    Publishing date 2015-12-23
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2041081-5
    ISSN 1124-9390
    ISSN 1124-9390
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    Zs.A 5576: Show issues Location:
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  2. Article: Assessment of Growth and Development in Children With Hepatitis B Positivity.

    Sari, Tugba / Eren, Erdal / Koruk, Suda Tekin

    Gastroenterology research

    2014  Volume 7, Issue 5-6, Page(s) 131–136

    Abstract: Background: Chronic infections and liver diseases may influence the growth and development of children by leading to malnutrition. In this study, demographic characteristics, anthropometric measurements and laboratory findings for children with ... ...

    Abstract Background: Chronic infections and liver diseases may influence the growth and development of children by leading to malnutrition. In this study, demographic characteristics, anthropometric measurements and laboratory findings for children with hepatitis B positivity were analyzed.
    Methods: A total of 43 cases were admitted to our clinic between January 2012 and February 2013 and detected to have HBsAg positivity.
    Results: Malnutrition was detected in 11 cases (25.6%) and obesity in three cases (6.9%). Aspartate aminotransferase (AST) levels were significantly higher in malnourished patients compared to those without malnutrition. The weight to height was significantly higher in patients with positive HBeAg compared to children with negative HBeAg. We found that the weight standard deviation scores (SDS) ratios dropped as alanine aminotransferase (ALT) and AST levels increased and height SDS ratios decreased. In addition, body mass index (BMI) decreased as AST and alpha feto protein (AFP) values increased. While a significant relationship was not detected between insulin-like growth factor binding protein-3 (IGFBP-3) and insulin-like growth factor-1 (IGF-1) and ALT, a significantly negative correlation was detected between IGFBP-3 and IGF-1 and AST. We found a malnutrition rate of 25.6% in children with HBsAg positivity. We also found that weight and height SDS rates decreased as ALT and AST levels increased. In addition, we detected that BMI decreased as AST and AFP values increased.
    Conclusion: We consider that hepatic inflammation is the factor that affects growth. Monitoring of growth and development during follow-up of children who are detected to have HBsAg positivity would be beneficial to determine the mechanism and causes of growth retardation.
    Language English
    Publishing date 2014-12-27
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2475913-2
    ISSN 1918-2813 ; 1918-2805
    ISSN (online) 1918-2813
    ISSN 1918-2805
    DOI 10.14740/gr628e
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  3. Book ; Online: Oligosymptomatic kidney transplant patients with COVID-19

    Arpalı, Emre / Akyollu, Başak / Koçak, Burak / Yelken, Berna / Kalayoğlu, Münci / Türkmen, Aydın / Koruk, Süda Tekin / Kanbay, Mehmet (ORCID 0000-0002-1297-0675 & YÖK ID 110580)

    Transplantation Proceedings

    do they pose a risk to other recipients?

    2020  

    Abstract: The clinical course of viral infections in patients under immunosuppression can be atypical and/or fatal if not diagnosed and treated appropriately. The coronavirus disease 2019 (COVID-19) may also have an atypical presentation. Contrary to the general ... ...

    Abstract The clinical course of viral infections in patients under immunosuppression can be atypical and/or fatal if not diagnosed and treated appropriately. The coronavirus disease 2019 (COVID-19) may also have an atypical presentation. Contrary to the general opinion, transplant patients may be asymptomatic or oligosymptomatic, which could be a risk factor for underdiagnosis and the dissemination of this viral disease. This study presents the clinical features of 2 oligosymptomatic kidney transplant patients diagnosed with COVID-19. We suggest that new screening algorithms for COVID-19 should be reconsidered for the transplant patient population.
    Keywords Medicine ; Middle East respiratory syndrome coronavirus ; Coronavirus infections ; covid19
    Language English
    Publisher Elsevier
    Publishing country tr
    Document type Book ; Online
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  4. Article ; Online: Where do we stand in the control of rabies? Knowledge and practices among physicians in a health district in Turkey.

    Koruk, Suda Tekın / Koruk, Ibrahim / Kutlu, Seher

    Wilderness & environmental medicine

    2011  Volume 22, Issue 2, Page(s) 151–155

    Abstract: Objective: The aim of this study was to determine the level of knowledge of rabies transmission and control among physicians practicing in healthcare centers in Sanliurfa, Turkey where 2 cases of human rabies were reported in the past 12 months. ... ...

    Abstract Objective: The aim of this study was to determine the level of knowledge of rabies transmission and control among physicians practicing in healthcare centers in Sanliurfa, Turkey where 2 cases of human rabies were reported in the past 12 months. Implementation issues regarding the current guidelines will also be discussed.
    Methods: A cross-sectional study was conducted among 84 physicians practicing in healthcare centers in Sanliurfa, located in the Southeastern Anatolian region of Turkey.
    Results: Among physicians, average duration of medical practice was 8.5 ± 6.7 years. The correct incubation period of rabies cases was known by 57.1% of the physicians. While 88.1% of physicians were aware of possible exposure routes, only 44.0% of them had the information that mucosal contact may also lead to transmission. While 96.4% of the physicians correctly indicated that cats and dogs can transmit the disease, the fact that foxes also have a role in transmission was known by only 48.8%. Post-exposure prophylaxis was correctly indicated by 65.5% of participants, but only 17.9% had correct information about pre-exposure prophylaxis.
    Conclusion: An important approach in rabies control is to increase community awareness, particularly among healthcare providers. It was found that basic management issues and insufficient awareness still exist despite the presence of legal regulations. To control rabies, the issue must be dealt with locally, through both economic and social means, by supporting rabies control efforts of local health and agricultural directorate managers and by encouraging collaboration with academics.
    MeSH term(s) Adult ; Attitude of Health Personnel ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Practice Patterns, Physicians' ; Rabies/epidemiology ; Rabies/prevention & control ; Rabies/transmission ; Surveys and Questionnaires ; Turkey/epidemiology
    Language English
    Publishing date 2011-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1238909-2
    ISSN 1545-1534 ; 1080-6032
    ISSN (online) 1545-1534
    ISSN 1080-6032
    DOI 10.1016/j.wem.2010.12.008
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    Zs.A 3025: Show issues Location:
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  5. Article ; Online: Increased liver mast cells in patients with chronic hepatitis C.

    Koruk, Suda Tekin / Ozardali, Ilyas / Dincoglu, Dilnur / Bitiren, Muharrem

    Indian journal of pathology & microbiology

    2011  Volume 54, Issue 4, Page(s) 736–740

    Abstract: Background and aim: The aim of the study was to investigate the mast cell (MC) concentration in the liver tissue of patients diagnosed with chronic hepatitis C and to determine whether there was a correlation with clinical and pathological ... ...

    Abstract Background and aim: The aim of the study was to investigate the mast cell (MC) concentration in the liver tissue of patients diagnosed with chronic hepatitis C and to determine whether there was a correlation with clinical and pathological characteristics of patients.
    Materials and methods: The study was conducted on liver biopsy samples from 60 patients with chronic hepatitis C. Clinical and laboratory data were obtained from follow-up records. Stained liver biopsies were examined. Immunohistochemical staining was performed by using an anti-c-kit antibody. Patients were divided into four groups (minimal, mild, moderate, and severe) based on the intensity of inflammation and their hepatic activity index scores and into two groups (no-mild, moderate-severe) according to fibrosis grade.
    Results: Among patients enrolled, 60.0% (n=36) were men with a mean age of 48.3 ± 12.7 (range 18-64) years. The mean number of mast cells per portal area in the liver was 0.87 ± 0.86 (0-4.0). No correlation was found between alanine aminotransferase (ALT) and hepatitis C virus (HCV). Ribonucleic acid ( RNA ) levels and the degree of inflammation of cases with number of mast cells and liver steatosis (P>0.05). As the degree of fibrosis increased in the liver so did the number of mast cells in portal areas (P=0.001). On the other hand, no correlation was found between the degree of fibrosis and the number of MCs in the sinusoids and steatosis (P<0.05). The increase in the number of MCs in the portal areas correlated with an increase in liver steatosis (t: 0.02, P=0.04).
    Conclusion: In light of these findings, it appears possible that MC accumulation in chronic HCV patients may be used as an indicator of fibrosis and possibly be considered in the follow-up of these patients.
    MeSH term(s) Adolescent ; Adult ; Biopsy ; Female ; Hepatitis C, Chronic/diagnosis ; Hepatitis C, Chronic/pathology ; Humans ; Immunohistochemistry ; Liver/pathology ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/pathology ; Male ; Mast Cells/immunology ; Microscopy ; Middle Aged ; Prognosis ; Severity of Illness Index ; Young Adult
    Language English
    Publishing date 2011-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/0377-4929.91510
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  6. Article ; Online: Decreasing oxidative stress in response to treatment in patients with brucellosis: could it be used to monitor treatment?

    Karaagac, Leman / Koruk, Suda Tekin / Koruk, Ibrahim / Aksoy, Nurten

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2011  Volume 15, Issue 5, Page(s) e346–9

    Abstract: Objectives: The aims of this study were to evaluate oxidant and antioxidant status in patients with acute brucellosis before and after therapy, and to determine whether this index could be used to monitor the treatment of brucellosis.: Methods: ... ...

    Abstract Objectives: The aims of this study were to evaluate oxidant and antioxidant status in patients with acute brucellosis before and after therapy, and to determine whether this index could be used to monitor the treatment of brucellosis.
    Methods: Thirty patients with a diagnosis of acute brucellosis and 37 healthy volunteers were enrolled in the study. Total antioxidant status (TAS) and total oxidant status (TOS) were measured in patients before and after therapy, and an oxidative stress index (OSI) was calculated. These measurements were also taken for the healthy control group and the values were compared.
    Results: Plasma levels of TOS and OSI were significantly higher in patients with brucellosis before therapy as compared to the treated group (t: 11.19, p<0.000 and t: 9.91, p<0.000, respectively). After treatment, TOS and OSI levels were lower, whereas in contrast, TAS levels were significantly higher (t: -4.17, p<0.000). TOS and OSI levels were found to be significantly higher in the patients before treatment than in the control group (t: 15.01, p<0.000 and t: 15.00, p<0.000, respectively). TAS levels in patients before treatment were lower than in the controls and the difference was significant (t: -8.03, p<0.000). TOS and OSI levels were significantly higher in the treated group than in the control group (t: 4.58, p<0.000 and t: 9.91, p<0.000, respectively). TAS levels in the treated group were lower than in the control group and the difference was significant (t: -3.02, p<0.004).
    Conclusion: Reduced TAS capacity and elevated TOS levels may lead to considerable oxidative stress in brucellosis. Increased oxidative stress may cause severe oxidative damage in the body, and even though this damage ameliorates considerably with 6weeks of treatment, normal healthy levels are not attained. In addition, it appears possible that these oxidant and antioxidant parameters could be used to monitor treatment.
    MeSH term(s) Acute Disease ; Adolescent ; Adult ; Aged ; Antioxidants/analysis ; Brucellosis/metabolism ; Brucellosis/therapy ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Oxidants/blood ; Oxidative Stress/physiology ; Treatment Outcome
    Chemical Substances Antioxidants ; Oxidants
    Language English
    Publishing date 2011-05
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2011.01.009
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    Zs.A 4516: Show issues Location:
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  7. Article ; Online: Prolidase and oxidative stress in chronic hepatitis C.

    Duygu, Fazilet / Koruk, Suda Tekin / Karsen, Hasan / Aksoy, Nurten / Taskin, Abdullah / Hamidanoglu, Melek

    Journal of clinical laboratory analysis

    2012  Volume 26, Issue 4, Page(s) 232–237

    Abstract: Background: Hepatitis C infection represents a common healthcare issue worldwide. The present trial was designed to investigate the role of prolidase, an enzyme that is significantly involved in the biosynthesis of collagen, and of the oxidative stress ... ...

    Abstract Background: Hepatitis C infection represents a common healthcare issue worldwide. The present trial was designed to investigate the role of prolidase, an enzyme that is significantly involved in the biosynthesis of collagen, and of the oxidative stress that is considered to be involved in the pathogenesis of various diseases, in the chronic hepatitis C infection. The trial was performed to assess the serum prolidase enzyme level and the oxidative-antioxidative status and to determine the relation between the serum prolidase activity and the oxidative stress parameters.
    Methods: A total of 95 individuals, including 55 patients with chronic hepatitis C infection (CHC) and 40 healthy adults, were enrolled in the trial. The values for prolidase, the total antioxidant status (TAS), the total oxidative stress (TOS), the oxidative stress index (OSI), sulfhydryl (SH), lipid peroxidation LOOH, catalase (CAT), and ceruloplasmin were measured and compared between the patient groups.
    Results: The prolidase, TOS, LOOH, CAT, and the OSI values were higher in the chronic hepatitis C group compared to the control group (P < 0.001). The TAS, SH, and ceruloplasmin levels were lower in the CHC group relative to the control group (P < 0.001).
    Conclusion: We suppose that the values of prolidase and the oxidative stress are increased while the antioxidant levels are decreased in CHC. As a result, prolidase and the oxidative stress seem to be related with the progression of the disease.
    MeSH term(s) Adolescent ; Adult ; Aged ; Case-Control Studies ; Catalase/blood ; Dipeptidases/blood ; Dipeptidases/metabolism ; Female ; Hepatitis C, Chronic/blood ; Hepatitis C, Chronic/enzymology ; Hepatitis C, Chronic/pathology ; Humans ; Lipid Peroxidation ; Male ; Middle Aged ; Oxidative Stress/physiology ; Statistics, Nonparametric ; Sulfhydryl Compounds/blood
    Chemical Substances Sulfhydryl Compounds ; Catalase (EC 1.11.1.6) ; Dipeptidases (EC 3.4.13.-) ; proline dipeptidase (EC 3.4.13.9)
    Language English
    Publishing date 2012-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645095-7
    ISSN 1098-2825 ; 0887-8013
    ISSN (online) 1098-2825
    ISSN 0887-8013
    DOI 10.1002/jcla.21510
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    Zs.A 2471: Show issues Location:
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  8. Article: Decreasing oxidative stress in response to treatment in patients with brucellosis: could it be used to monitor treatment?

    Karaagac, Leman / Koruk, Suda Tekin / Koruk, Ibrahim / Aksoy, Nurten

    International journal of infectious diseases. 2011 May, v. 15, no. 5

    2011  

    Abstract: OBJECTIVES: The aims of this study were to evaluate oxidant and antioxidant status in patients with acute brucellosis before and after therapy, and to determine whether this index could be used to monitor the treatment of brucellosis. METHODS: Thirty ... ...

    Abstract OBJECTIVES: The aims of this study were to evaluate oxidant and antioxidant status in patients with acute brucellosis before and after therapy, and to determine whether this index could be used to monitor the treatment of brucellosis. METHODS: Thirty patients with a diagnosis of acute brucellosis and 37 healthy volunteers were enrolled in the study. Total antioxidant status (TAS) and total oxidant status (TOS) were measured in patients before and after therapy, and an oxidative stress index (OSI) was calculated. These measurements were also taken for the healthy control group and the values were compared. RESULTS: Plasma levels of TOS and OSI were significantly higher in patients with brucellosis before therapy as compared to the treated group (t: 11.19, p<0.000 and t: 9.91, p<0.000, respectively). After treatment, TOS and OSI levels were lower, whereas in contrast, TAS levels were significantly higher (t: −4.17, p<0.000). TOS and OSI levels were found to be significantly higher in the patients before treatment than in the control group (t: 15.01, p<0.000 and t: 15.00, p<0.000, respectively). TAS levels in patients before treatment were lower than in the controls and the difference was significant (t: −8.03, p<0.000). TOS and OSI levels were significantly higher in the treated group than in the control group (t: 4.58, p<0.000 and t: 9.91, p<0.000, respectively). TAS levels in the treated group were lower than in the control group and the difference was significant (t: −3.02, p<0.004). CONCLUSION: Reduced TAS capacity and elevated TOS levels may lead to considerable oxidative stress in brucellosis. Increased oxidative stress may cause severe oxidative damage in the body, and even though this damage ameliorates considerably with 6weeks of treatment, normal healthy levels are not attained. In addition, it appears possible that these oxidant and antioxidant parameters could be used to monitor treatment.
    Keywords antioxidants ; brucellosis ; oxidants ; oxidative stress ; patients ; stress response ; therapeutics ; volunteers
    Language English
    Dates of publication 2011-05
    Size p. e346-e349.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2011.01.009
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  9. Article: Molecular epidemiology of HIV-1 strains in the south-east and east of Turkey

    Çelen, Mustafa Kemal / Sayan, Murat / Dal, Tuba / Ayaz, Celal / Tekin, Alicem / Özekinci, Tuncer / Koruk, Suda Tekin / Barcin, Tunga / Tekin, Recep / Dal, Mehmet Sinan / Kalkanlı, Sevgi

    Hainan Medical University Asian Pacific Journal of Tropical Biomedicine. 2015 Sept., v. 5

    2015  

    Abstract: To detect the subtype characterization and drug-resistant mutations in HIV-1 strains after the refugee movement from Syria to Turkey between 2011 and 2014 in south east border lines.A total of 65 patients were included in this study, of which 57 (88%) ... ...

    Abstract To detect the subtype characterization and drug-resistant mutations in HIV-1 strains after the refugee movement from Syria to Turkey between 2011 and 2014 in south east border lines.A total of 65 patients were included in this study, of which 57 (88%) patients were antiretroviral therapy-naive patients. HIV-1 RNA was detected and quantified by real-time PCR assay. HIV-1 subtypes and circulating recombinant forms (CRFs) were identified by phylogenetic analysis (neighbor-joining method), and drug-resistant mutations were analyzed.Three major HIV groups were indicated. Two of these groups were located in subtype B. The other group showed heterogeneity. Subtype B (48/65, 73.8%), followed by CRFs (12/65, 18.5%) was the most common strain. Subtype of CRFs consisted of CRF01_AE (9/65, 13.8%) and CRF02_AG (3/65, 4.6%). Subtype C (1/65, 1.5%), sub-subtypes A1 (2/65, 3.1%) and F1 (2/65, 3.1%) were also detected with low prevalence. The rate of overall primary antiretroviral resistance was 4.9% (3/61). Drug-resistant rate for non-nucleoside reverse transcriptase inhibitors was 4.9%. The thymidine analogue mutation rate was 13.1% (8/61).HIV molecular epidemiology studies are necessary to determine transmission patterns and spread. Subtype B and CRF01_AE, CRF02_AG are the most prevalent strains in the south-east of Turkey. However, subtype C, sub-subtypes A1 and F1 are of low prevalence but persist in the south-east of Turkey. In the near future, changing of HIV epidemiology will be possible in Turkey due to migration movement in border lines and resistance testing will play an important role in HIV management.
    Keywords Human immunodeficiency virus 1 ; RNA ; RNA-directed DNA polymerase ; antiretroviral agents ; drug resistance ; enzyme inhibitors ; molecular epidemiology ; mutation ; mutation rate ; patients ; phylogeny ; quantitative polymerase chain reaction ; thymidine ; Syria ; Turkey (country)
    Language English
    Dates of publication 2015-09
    Size p. 773-777.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 2221-1691
    DOI 10.1016/j.apjtb.2015.07.009
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  10. Article ; Online: Comparative analysis of cerebrospinal fluid adenosine deaminase activity in meningitis.

    Karsen, Hasan / Koruk, Suda Tekin / Karahocagil, Mustafa Kasim / Calisir, Celal / Baran, Fatma Corcu

    Swiss medical weekly

    2011  Volume 141, Page(s) w13214

    Abstract: Aim: The purpose is to determine the cut-off value of adenosine deaminase (ADA) activity in cerebrospinal fluid (CSF) of patients with tuberculous and non-tuberculous meningitis, and to assess its value in differential diagnosis.: Material and methods! ...

    Abstract Aim: The purpose is to determine the cut-off value of adenosine deaminase (ADA) activity in cerebrospinal fluid (CSF) of patients with tuberculous and non-tuberculous meningitis, and to assess its value in differential diagnosis.
    Material and methods: This study was conducted in 91 patients with meningitis in two university hospitals in Turkey. 24 patients had tuberculous meningitis (TBM), 25 purulent meningitis (PM), 25 aseptic meningitis (AM) and 17 neurobrucellosis (BM). ADA activity of CSF was quantified by colorimetry.
    Results: In our study, mean ADA values in CSF were 28.34 ± 14.83 IU/L in TB cases, 8.71 ± 5.83 IU/L in BM, 6.18 ± 2.54 IU/L in PM and 3.43 ± 3.48 U/L in AM cases. If we accept for CSF ADA an activity cut-off value of 12.5 IU/L for differential diagnosis of TBM and BM, its sensitivity was 92% and specificity was 88%. If we accept 12.35 IU/L for differential diagnosis of TBM and PM, its sensitivity was 92% and specificity was 100%. If we accept 6.45 IU/L for differential diagnosis of TBM and AM, its sensitivity was 100% and specificity was 92%. Additionally, we examined the cases after dividing them into two groups, viz. TB and non-TB. If we accept an ADA activity cut-off level of 11 IU/L for differential diagnosis of TB and non-TB by applying ROC analysis, its sensitivity was 92% and specificity was 90%.
    Conclusion: The sensitivity and specificity for CSF ADA activity are markedly high in differential diagnosis of TB from non-TB. Hence CSF ADA activity may be used as a simple, cost-effective and reliable test for early differential diagnosis of TB.
    MeSH term(s) Adenosine Deaminase/cerebrospinal fluid ; Adolescent ; Adult ; Brucellosis/cerebrospinal fluid ; Brucellosis/diagnosis ; Brucellosis/enzymology ; Diagnosis, Differential ; Female ; Humans ; Male ; Meningitis, Aseptic/cerebrospinal fluid ; Meningitis, Aseptic/diagnosis ; Meningitis, Aseptic/enzymology ; Middle Aged ; Predictive Value of Tests ; ROC Curve ; Tuberculosis, Meningeal/cerebrospinal fluid ; Tuberculosis, Meningeal/diagnosis ; Tuberculosis, Meningeal/enzymology
    Chemical Substances Adenosine Deaminase (EC 3.5.4.4)
    Language English
    Publishing date 2011
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2036179-8
    ISSN 1424-3997 ; 1424-7860
    ISSN (online) 1424-3997
    ISSN 1424-7860
    DOI 10.4414/smw.2011.13214
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