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  1. Book: Prophylaxe und Therapie von venösen Thromboembolien in der täglichen Praxis

    Langer, Florian / Grünewald, Martin / Koscielny, Jürgen K.

    ein Status quo zur parenteralen Antikoagulation

    (Praxis Report ; 10. Jahrgang, Heft 2 (März 2018))

    2018  

    Author's details Herausgeber [und Autor] PD Dr. med. Florian Langer; Mitautoren PD Dr. med. Martin Grünewald, PD Dr. med. Jürgen Koscielny
    Series title Praxis Report ; 10. Jahrgang, Heft 2 (März 2018)
    Collection
    Language German
    Size 11 Seiten, Illustrationen, Diagramme
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT019765861
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Modernes präoperatives Screening und Management primärer Hämostasestörungen

    Koscielny, Jürgen K.

    2004  

    Author's details vorgelegt von Koscielny, Jürgen
    Language German ; English
    Size 34 Bl.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Habil.-Schr., 2004
    Note Zsfassung in engl. Sprache
    HBZ-ID HT014348337
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Iso- und hypervolämische Hämodilution

    Koscielny, Jürgen K.

    1990  

    Author's details vorgelegt von Jürgen K. Koscielny
    Language German
    Size 2 Mikrofiches : 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Saarbrücken, Univ., Diss., 1990
    Note Mikroreprod. e. Ms.: Getr. Zählung : Ill., graph. Darst.
    HBZ-ID HT003714543
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online ; Thesis: Modernes präoperatives Screening und Management primärer Hämostasestörungen

    Koscielny, Jürgen K

    2004  

    Author's details von Koscielny, Jürgen
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Humboldt-Univ., Habil--Berlin, 2004
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book ; Online ; Thesis: Modernes präoperatives Screening und Management primärer Hämostasestörungen

    Koscielny, Jürgen K. [Verfasser]

    2004  

    Author's details von Koscielny, Jürgen
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  6. Book ; Thesis: Iso- und hypervolämische Hämodilution

    Koscielny, Jürgen K

    1990  

    Author's details Jürgen K. Koscielny
    Language Undetermined
    Size 2 Mikrofiches, 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis @Saarbrücken, Univ., Diss. : 1990
    Note Mikroreprod. e. Ms. Getr. Zählung : Ill., graph. Darst
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article: Capillary Microscopic and Rheological Dimensions for the Diagnosis of von Willebrand Disease in Comparison to other Haemorrhagic Diatheses

    Koscielny, Jürgen K. / Latza, Reinhard / Mürsdorf, Stefan / Mrowietz, Christof / Kiesewetter, Holger / Wenzel, Ernst / Jung, Friedrich

    Thrombosis and Haemostasis

    2000  Volume 83, Issue 12, Page(s) 981–988

    Abstract: It is known that angiodysplasia influence macrocirculation as well as microcirculation in patients with vWD. In the present study it was examined if intravital capillary microscopic dimensions (morphologic and dynamic) in skin (nailfold) in combination ... ...

    Abstract It is known that angiodysplasia influence macrocirculation as well as microcirculation in patients with vWD. In the present study it was examined if intravital capillary microscopic dimensions (morphologic and dynamic) in skin (nailfold) in combination with rheologic parameters could give indications for the presence of vWD in patients with haemorrhagic diathesis. Patients with vWD (n = 100; 92 type 1: definite type 1:78 and possible type 1:14; 8 type 2A) have in comparison to patients with other haemorrhagic diathesis [thrombocytopathy (n = 122), thrombocytopenia (n = 101), severe haemophilia A (n = 50) and severe haemophilia B (n = 20), congenital dysfibrinogenaemia (n = 22), oral anticoagulation with phenprocoumone (n = 112)] and to apparently healthy subjects (n = 100) a significantly increased capillary torquation (median index: 3.5), a venolar and an arteriolar capillary dilatation (median: 16.5 µm; median: 15.1 µm) and the highest part of microscopic bleedings (extravasates) with 40% in the video capillary microscopy as morphological changes. Only the congenital dysfibrinogenaemia appears with a larger dilatation in venolar capillaries (median: 14.5 µm). Microscopic bleedings are much less common in other haemorrhagic diatheses with a frequency between 4% and 13%. In the vWD a significantly reduced duration of reactive hyperaemia (median: 150 sec). This is the only dynamic change that can be taken as a possible hint for a loss of flexibility within the precapillary vessels. A significantly reduced plasma viscosity (< 1.25 mPas) is typical for the vWD due to the increase of the shear stress in blood plasma because of the reduction of vWF-activities. Changes of the capillary morphology (dilatation, extravasates, capillary torquation) and the hypoplasmaviscosity are most sensitive for the vWD (75%, 65%, 40%, 80%) with a fairly high specifity (up to 93%) and a positive predictive value of 99%. As a conclusion it seems reasonable to discuss the introduction of video capillary microscopy as a screening test for haemostasiological and angiological centers.
    Keywords vWD ; haemorrhagic diatheses ; capillary microscopy ; rheology ; microangiopathy
    Language English
    Publishing date 2000-01-01
    Publisher Schattauer GmbH
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0037-1614160
    Database Thieme publisher's database

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