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  1. Article: ICU Admission Tool for Congenital Heart Catheterization (iCATCH): A Predictive Model for High Level Post-Catheterization Care and Patient Management.

    Quinn, Brian P / Shirley, Lauren C / Yeh, Mary J / Gauvreau, Kimberlee / Ibla, Juan C / Kotin, Sarah G / Porras, Diego / Bergersen, Lisa J

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2022  Volume 23, Issue 10, Page(s) 822–830

    Abstract: Objectives: Currently, there are no prediction tools available to identify patients at risk of needing high-complexity care following cardiac catheterization for congenital heart disease. We sought to develop a method to predict the likelihood a patient ...

    Abstract Objectives: Currently, there are no prediction tools available to identify patients at risk of needing high-complexity care following cardiac catheterization for congenital heart disease. We sought to develop a method to predict the likelihood a patient will require intensive care level resources following elective cardiac catheterization.
    Design: Prospective single-center study capturing important patient and procedural characteristics for predicting discharge to the ICU. Characteristics significant at the 0.10 level in the derivation dataset (July 1, 2017 to December 31, 2019) were considered for inclusion in the final multivariable logistic regression model. The model was validated in the testing dataset (January 1, 2020 to December 31, 2020). The novel pre-procedure cardiac status (PCS) feature, collection started in January 2019, was assessed separately in the final model using the 2019 through 2020 dataset.
    Setting: Tertiary pediatric heart center.
    Patients: All elective cases coming from home or non-ICU who underwent a cardiac catheterization from July 2017 to December 2020.
    Interventions: None.
    Measurements and main results: A total of 2,192 cases were recorded in the derivation dataset, of which 11% of patients ( n = 245) were admitted to the ICU, while 64% ( n = 1,413) were admitted to a medical unit and 24% ( n = 534) were discharged home. In multivariable analysis, the following predictors were identified: 1) weight less than 5 kg and 5-9.9 kg, 2) presence of systemic illness, 3) recent cardiac intervention less than 90 days, and 4) ICU Admission Tool for Congenital Heart Catheterization case type risk categories (1-5), with C -statistics of 0.79 and 0.76 in the derivation and testing cohorts, respectively. The addition of the PCS feature fit into the final model resulted in a C -statistic of 0.79.
    Conclusions: The creation of a validated pre-procedural risk prediction model for ICU admission following congenital cardiac catheterization using a large volume, single-center, academic institution will improve resource allocation and prediction of capacity needs for this complex patient population.
    MeSH term(s) Cardiac Catheterization/adverse effects ; Child ; Heart Defects, Congenital/epidemiology ; Heart Defects, Congenital/surgery ; Humans ; Intensive Care Units ; Logistic Models ; Patient Admission ; Prospective Studies ; Risk Factors
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000003028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Catheterization for Congenital Heart Disease Adjustment for Risk Method II.

    Quinn, Brian P / Gunnelson, Lauren C / Kotin, Sarah G / Gauvreau, Kimberlee / Yeh, Mary J / Hasan, Babar / Lozier, John / Barry, Oliver M / Shahanavaz, Shabana / Batlivala, Sarosh P / Salavitabar, Arash / Foerster, Susan / Goldstein, Bryan / Divekar, Abhay / Holzer, Ralf / Nicholson, George T / O'Byrne, Michael L / Whiteside, Wendy / Bergersen, Lisa

    Circulation. Cardiovascular interventions

    2024  Volume 17, Issue 3, Page(s) e012834

    Abstract: Background: Current metrics used to adjust for case mix complexity in congenital cardiac catheterization are becoming outdated due to the introduction of novel procedures, innovative technologies, and expanding patient subgroups. This study aims to ... ...

    Abstract Background: Current metrics used to adjust for case mix complexity in congenital cardiac catheterization are becoming outdated due to the introduction of novel procedures, innovative technologies, and expanding patient subgroups. This study aims to develop a risk adjustment methodology introducing a novel, clinically meaningful adverse event outcome and incorporating a modern understanding of risk.
    Methods: Data from diagnostic only and interventional cases with defined case types were collected for patients ≤18 years of age and ≥2.5 kg at all Congenital Cardiac Catheterization Project on Outcomes participating centers. The derivation data set consisted of cases performed from 2014 to 2017, and the validation data set consisted of cases performed from 2019 to 2020. Severity level 3 adverse events were stratified into 3 tiers by clinical impact (3a/b/c); the study outcome was clinically meaningful adverse events, severity level ≥3b (3bc/4/5).
    Results: The derivation data set contained 15 224 cases, and the validation data set included 9462 cases. Clinically meaningful adverse event rates were 4.5% and 4.2% in the derivation and validation cohorts, respectively. The final risk adjustment model included age <30 days, Procedural Risk in Congenital Cardiac Catheterization risk category, and hemodynamic vulnerability score (C statistic, 0.70; Hosmer-Lemeshow
    Conclusions: CHARM II (Congenital Heart Disease Adjustment for Risk Method II) risk adjustment methodology allows for equitable comparison of clinically meaningful adverse events among institutions and operators with varying patient populations and case mix complexity performing pediatric cardiac catheterization.
    MeSH term(s) Child ; Humans ; Infant ; Risk Factors ; Treatment Outcome ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/methods ; Heart Defects, Congenital/diagnosis ; Heart Defects, Congenital/therapy ; Hemodynamics ; Risk Adjustment/methods
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2450797-0
    ISSN 1941-7632 ; 1941-7640
    ISSN (online) 1941-7632
    ISSN 1941-7640
    DOI 10.1161/CIRCINTERVENTIONS.123.012834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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