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Article ; Online: Small molecules that inhibit the late stage of Munc13-4-dependent secretory granule exocytosis in mast cells.

Bruinsma, Stephen / James, Declan J / Quintana Serrano, Melanie / Esquibel, Joseph / Woo, Sang Su / Kielar-Grevstad, Elle / Crummy, Ellen / Qurashi, Rehan / Kowalchyk, Judy A / Martin, Thomas F J

The Journal of biological chemistry

2018  Volume 293, Issue 21, Page(s) 8217–8229

Abstract: ... ...

Abstract Ca
MeSH term(s) Animals ; Cell Degranulation/drug effects ; Exocytosis ; Leukemia, Basophilic, Acute/drug therapy ; Leukemia, Basophilic, Acute/metabolism ; Leukemia, Basophilic, Acute/pathology ; Mast Cells/drug effects ; Mast Cells/pathology ; Membrane Fusion ; Proteins/genetics ; Proteins/metabolism ; Rats ; Secretory Vesicles/drug effects ; Secretory Vesicles/pathology ; Small Molecule Libraries/pharmacology ; Tumor Cells, Cultured
Chemical Substances Proteins ; Small Molecule Libraries ; Unc13d protein, rat
Language English
Publishing date 2018-04-03
Publishing country United States
Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID 2997-x
ISSN 1083-351X ; 0021-9258
ISSN (online) 1083-351X
ISSN 0021-9258
DOI 10.1074/jbc.RA117.001547
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