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  1. Book ; Online: Die Inschriften des Stadtgottesackers in Halle an der Saale (1550-1700) : Quellen zum Bürgertum einer Stadt in der frühen Neuzeit

    Krüger, Klaus

    2021  

    Keywords Literary studies: classical, early & medieval ; Literary studies: c 1500 to c 1800 ; Medieval history ; Funerary monuments ; inscriptions ; sepulchral culture ; Halle (Saale)
    Size 1 electronic resource (560 pages)
    Publisher De Gruyter
    Publishing place Berlin/Boston
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT021048807
    ISBN 9783110700213 ; 3110700212
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Glukokortikoide als Begleitmedikation in der Therapie der rheumatoiden Arthritis

    Krüger, Klaus

    (Refresher Rheumatologie ; 2017, Nr. 2 (April 2017))

    2017  

    Author's details K. Krüger
    Series title Refresher Rheumatologie ; 2017, Nr. 2 (April 2017)
    Collection
    Language German
    Size 11 Seiten, Illustrationen
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT019800633
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7150 -2017,2- verfügbar in Königswinter Königswinter

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  3. Book ; Thesis: 3D-Perfusion mittels Cone-beam-CT: Evaluierung für das Monitoring der transarteriellen Chemoembolisation mit Doxorubicin-eluting beads bei Patienten mit Lebermetastasen des malignen Melanoms

    Krüger, Kristina

    2015  

    Author's details vorgelegt von Kristina Krüger
    Language German
    Size 60 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 2015
    HBZ-ID HT018815065
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 D 1125 order for loan Magazin

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  4. Article ; Online: DMARD(„disease-modifying antirheumatic drug“)-Therapie bei früherer und aktiver Tumorerkrankung.

    Krüger, Klaus

    Zeitschrift fur Rheumatologie

    2023  Volume 82, Issue 3, Page(s) 206–211

    Abstract: In contrast to the original fear that treatment with disease-modifying antirheumatic drugs (DMARDs) and especially with biologic DMARDs (bDMARDs), was associated with an increased risk of the induction of malignancies, this has meanwhile fortunately not ... ...

    Title translation DMARD (disease-modifying antirheumatic drug) treatment in patients with former or current cancer.
    Abstract In contrast to the original fear that treatment with disease-modifying antirheumatic drugs (DMARDs) and especially with biologic DMARDs (bDMARDs), was associated with an increased risk of the induction of malignancies, this has meanwhile fortunately not been confirmed over the long-term administration. Evaluations from register-based investigations as well as from other long-term cohort studies confirm that neither conventional DMARDs, such as methotrexate, nor tumor necrosis factor (TNF) inhibitors or biologics with a different mode of action show such a risk for induction of cancer or hematological malignancies (for skin tumors see the other article). Regarding the question whether recurrences of former malignancies can be induced by DMARDs, the database is considerably smaller; however, published investigations dealing with this topic so far signal that also in this respect no increased risk can be found. When comparing the individual substances with each other no substantial differences can be found. Although used in the treatment of hematological cancers, rituximab does not offer any advantages in comparison to other biologics. For the group of Janus kinase (JAK) inhibitors, which have been in use only for a few years, data outside the randomized controlled studies (which are limited in time and are conducted with a selected patient population) are limited so that a clear statement regarding the malignancy risk is not yet possible for these substances. In a solitary study comparing tofacitinib with TNF inhibitors in high-risk patients, the malignancy risk of the JAK inhibitor was increased compared to that under TNF inhibitor treatment; however, these results have not yet been confirmed by a second investigation.
    MeSH term(s) Humans ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Methotrexate/therapeutic use ; Biological Products/therapeutic use ; Janus Kinase Inhibitors/therapeutic use ; Neoplasms/drug therapy
    Chemical Substances Antirheumatic Agents ; Methotrexate (YL5FZ2Y5U1) ; Biological Products ; Janus Kinase Inhibitors
    Language German
    Publishing date 2023-02-09
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-023-01316-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Muss bei einer MTX-Therapie Folsäure/Folinsäure substituiert werden? Wenn ja, wie viel?

    Krüger, Klaus

    Zeitschrift fur Rheumatologie

    2023  Volume 82, Issue 3, Page(s) 246–247

    Title translation Must folic acid and folinic acid be substituted in methotrexate treatment? If yes, how much?
    MeSH term(s) Humans ; Folic Acid/therapeutic use ; Leucovorin/therapeutic use ; Methotrexate/therapeutic use ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy
    Chemical Substances Folic Acid (935E97BOY8) ; Leucovorin (Q573I9DVLP) ; Methotrexate (YL5FZ2Y5U1) ; Antirheumatic Agents
    Language German
    Publishing date 2023-02-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-023-01322-9
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  6. Book ; Online: Dante se mistieke reis : Tweede tog: Purgatorio, ingelei, vertaal, toegelig, vertolk

    Krüger, Kobus / van Aarde, Andries

    2020  

    Keywords Theology ; Dante ; Divina Commedia ; Purgatorio ; Middle Ages ; Virgil ; Hell ; Mysticism
    Size 1 electronic resource (464 pages)
    Publisher AOSIS
    Publishing place Durbanville
    Document type Book ; Online
    Note Afrikaans ; Open Access
    HBZ-ID HT021047309
    ISBN 9781928523260 ; 1928523269
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Book ; Thesis: Veno-venöse extrakorporale Membranoxygenerierung mit ausschließlich subkutaner, prophylaktischer Enoxaparin-Antikoagulation bei Patienten mit Lungenversagen

    Krüger, Kirsten

    eine retrospektive Studie

    2018  

    Author's details vorgelegt von Kirsten Brita Krüger
    Language German
    Size 47 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Freiburg im Breisgau
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg im Breisgau, 2018
    HBZ-ID HT019803697
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 E 1130 order for loan Magazin

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  8. Article ; Online: Komorbiditäten-Assessment durch die Fachassistentin – die ERIKO-Studie.

    Krüger, K

    Zeitschrift fur Rheumatologie

    2020  Volume 79, Issue Suppl 2, Page(s) 55–56

    Title translation Comorbidity assessment by nurses-the ERIKO study.
    MeSH term(s) Comorbidity ; Humans ; Nursing Assessment ; Surveys and Questionnaires
    Language German
    Publishing date 2020-09-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-020-00865-5
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  9. Article ; Online: Interstitielle Lungenerkrankung (ILD) – wann und wie behandeln?

    Krüger, K

    Zeitschrift fur Rheumatologie

    2020  Volume 79, Issue 8, Page(s) 780–781

    Title translation Interstitial Lung Disease (ILD)-when and how to treat.
    MeSH term(s) Humans ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/therapy ; Prognosis
    Language German
    Publishing date 2020-06-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-020-00829-9
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  10. Article ; Online: Neues zu Therapiestrategien bei der rheumatoiden Arthritis.

    Krüger, Klaus

    Zeitschrift fur Rheumatologie

    2022  Volume 81, Issue 2, Page(s) 118–124

    Abstract: Besides excellent guidelines and newly developed highly effective drugs, evidence-based strategic use of these new drugs has especially contributed to enormous advances in rheumatoid arthritis treatment, apparent especially since 2000. Currently, the ... ...

    Title translation Innovative strategies for treatment of rheumatoid arthritis.
    Abstract Besides excellent guidelines and newly developed highly effective drugs, evidence-based strategic use of these new drugs has especially contributed to enormous advances in rheumatoid arthritis treatment, apparent especially since 2000. Currently, the treat-to-target (T2T) strategy has proven to be the most successful in several studies and systematic reviews. The target is to achieve remission, which should be reached and sustained for an optimal outcome (i.e. stable over a long time period). If the initial disease-modifying antirheumatic drug (DMARD) treatment fails, the best strategy for continuing treatment is controversial, with swap or switch being open to debate (change within a class of drugs or change in the mechanism of action). Recent studies seem to indicate that switching to another mechanism of action is the most successful approach. A hotly discussed topic is the question whether DMARD treatment can or should be tapered when sustained remission has been achieved? Many patients wish for a reduction of drugs in cases of stable remission; however, the stable disease control might become destabilized by tapering. The main priority is the reduction or tapering of glucocorticoid treatment. When the decision for reduction of DMARD treatment is made together with the patient, a complete cessation bears a high risk of a flare, therefore, a careful step by step reduction of DMARD treatment should be preferred. In the case of a running combination, the question whether the conventional DMARD (mostly methotrexate), the biological (b)DMARD or targeted synthetic (ts)DMARD should be reduced first, must be decided on an individual basis. Most patients prefer to first reduce methotrexate and transfer to a monotherapy.
    MeSH term(s) Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Drug Administration Schedule ; Drug Therapy, Combination ; Humans ; Methotrexate/therapeutic use ; Remission Induction ; Treatment Outcome
    Chemical Substances Antirheumatic Agents ; Methotrexate (YL5FZ2Y5U1)
    Language German
    Publishing date 2022-01-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 124985-x
    ISSN 1435-1250 ; 0340-1855 ; 0301-6382
    ISSN (online) 1435-1250
    ISSN 0340-1855 ; 0301-6382
    DOI 10.1007/s00393-021-01144-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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