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  1. Article: Periarrestrhythmen – ein schmaler Grat. Teil I: der bradykarde Periarrest

    Kraft, Maximilian / Rusnak, Jonas / Biener, Moritz / Weilbacher, Frank

    NOTARZT

    2024  Volume 40, Issue 02, Page(s) 105–108

    Keywords Kreislaufstillstand ; Früherkennung ; Bradykardie ; kardiale Arrhythmien ; Schrittmachertherapie ; cardiac arrest ; early diagnosis ; bradycardia ; arrhythmias, cardiac ; cardiac pacing, artificial
    Language German
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2039417-2
    ISSN 1438-8693 ; 0177-2309
    ISSN (online) 1438-8693
    ISSN 0177-2309
    DOI 10.1055/a-2278-8542
    Database Thieme publisher's database

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  2. Article: Polytrauma- und Schwerverletztenbehandlung – aktuelle Leitlinienempfehlungen

    Hirsch, Svenja / Kraft, Maximilian / Weilbacher, Frank

    NOTARZT

    2023  Volume 39, Issue 04, Page(s) 221–227

    Keywords kritische Blutungen ; Atemwegsmanagement ; Notfallnarkose ; Schockraum ; Gerinnungsmanagement ; critical bleeding ; airway management ; emergency anesthesia ; shock room ; coagulation management
    Language German
    Publishing date 2023-08-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2039417-2
    ISSN 1438-8693 ; 0177-2309
    ISSN (online) 1438-8693
    ISSN 0177-2309
    DOI 10.1055/a-2101-3962
    Database Thieme publisher's database

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  3. Article ; Online: Developmental exposure to triclosan and benzophenone-2 causes morphological alterations in zebrafish (Danio rerio) thyroid follicles and eyes

    Kraft, Maximilian / Gölz, Lisa / Rinderknecht, Maximilian / Koegst, Johannes / Braunbeck, T. / Baumann, Lisa

    Environ Sci Pollut Res. 2023 Mar., v. 30, no. 12 p.33711-33724

    2023  

    Abstract: Thyroid hormones (THs) regulate a multitude of developmental and metabolic processes, which are responsible for vertebrate development, growth, and maintenance of homeostasis. THs also play a key role in neurogenesis of vertebrates and thus affect eye ... ...

    Abstract Thyroid hormones (THs) regulate a multitude of developmental and metabolic processes, which are responsible for vertebrate development, growth, and maintenance of homeostasis. THs also play a key role in neurogenesis of vertebrates and thus affect eye development, which is vital for foraging efficiency and for effective escape from predation. Currently, there are no validated test guidelines for the assessment of TH system-disrupting chemicals (THSDCs) in fish. Consequently, the present study was designed to demonstrate the suitability of novel thyroid-related endpoints in early life-stages of fish. Embryos of a transgenic zebrafish (Danio rerio) line expressing the reporter gene tg:mCherry in their thyrocytes were used to investigate the effects of the environmental THSDCs triclosan (TCS, antibacterial agent) and benzophenone-2 (BP-2, UV filter) on thyroid follicle and eye development. Both BP-2 and TCS caused thyroid follicle hyperplasia in transgenic zebrafish, thus confirming their role as THSDCs. The effect intensity on follicle size and fluorescence was comparable with a 1.7-fold increase for BP-2 and 1.6-fold for TCS. Alterations of the cellular structures of the retina indicate an impact of both substances on eye development, with a stronger impact of TCS. With respect to guideline development, results provide further evidence for the suitability of morphological changes in thyroid follicles and the eyes as novel endpoints for the sensitive assessment of THSD-related effects in fish.
    Keywords Danio rerio ; UV filters ; antibiotics ; benzophenones ; fish ; fluorescence ; genetically modified organisms ; guidelines ; homeostasis ; hyperplasia ; neurogenesis ; predation ; reporter genes ; retina ; triclosan
    Language English
    Dates of publication 2023-03
    Size p. 33711-33724.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-24531-2
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  4. Article ; Online: Developmental exposure to triclosan and benzophenone-2 causes morphological alterations in zebrafish (Danio rerio) thyroid follicles and eyes.

    Kraft, Maximilian / Gölz, Lisa / Rinderknecht, Maximilian / Koegst, Johannes / Braunbeck, Thomas / Baumann, Lisa

    Environmental science and pollution research international

    2022  Volume 30, Issue 12, Page(s) 33711–33724

    Abstract: Thyroid hormones (THs) regulate a multitude of developmental and metabolic processes, which are responsible for vertebrate development, growth, and maintenance of homeostasis. THs also play a key role in neurogenesis of vertebrates and thus affect eye ... ...

    Abstract Thyroid hormones (THs) regulate a multitude of developmental and metabolic processes, which are responsible for vertebrate development, growth, and maintenance of homeostasis. THs also play a key role in neurogenesis of vertebrates and thus affect eye development, which is vital for foraging efficiency and for effective escape from predation. Currently, there are no validated test guidelines for the assessment of TH system-disrupting chemicals (THSDCs) in fish. Consequently, the present study was designed to demonstrate the suitability of novel thyroid-related endpoints in early life-stages of fish. Embryos of a transgenic zebrafish (Danio rerio) line expressing the reporter gene tg:mCherry in their thyrocytes were used to investigate the effects of the environmental THSDCs triclosan (TCS, antibacterial agent) and benzophenone-2 (BP-2, UV filter) on thyroid follicle and eye development. Both BP-2 and TCS caused thyroid follicle hyperplasia in transgenic zebrafish, thus confirming their role as THSDCs. The effect intensity on follicle size and fluorescence was comparable with a 1.7-fold increase for BP-2 and 1.6-fold for TCS. Alterations of the cellular structures of the retina indicate an impact of both substances on eye development, with a stronger impact of TCS. With respect to guideline development, results provide further evidence for the suitability of morphological changes in thyroid follicles and the eyes as novel endpoints for the sensitive assessment of THSD-related effects in fish.
    MeSH term(s) Animals ; Triclosan/toxicity ; Triclosan/metabolism ; Zebrafish/genetics ; Thyroid Gland ; Benzophenones/toxicity ; Thyroid Hormones/metabolism ; Water Pollutants, Chemical/metabolism
    Chemical Substances Triclosan (4NM5039Y5X) ; 2,2',4,4'-tetrahydroxybenzophenone (PRR8K3H9VN) ; Benzophenones ; Thyroid Hormones ; Water Pollutants, Chemical
    Language English
    Publishing date 2022-12-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-24531-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  5. Book: Fabrikshygiene / 1

    Kraft, Max

    Darstellung der neuesten Vorrichtungen und Einrichtungen für Arbeiterschutz und Wohlfahrt ; nach den neuesten Erfahrungen, den einschlägigen Gesetzen und Verordnungen, der einschlägigen Statistik in Deutschland und Oesterreich

    1891  

    Author's details hrsg. von Max Kraft
    Collection Fabrikshygiene
    Language German
    Size VIII, 627 S. : zahlr. Ill.
    Publisher Spielhagen & Schurich
    Publishing place Wien
    Publishing country XA-AAAT
    Document type Book
    HBZ-ID HT006446603
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 7503 order for loan Magazin

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  6. Book ; Collection: Fabrikshygiene

    Kraft, Max

    Darstellung der neuesten Vorrichtungen und Einrichtungen für Arbeiterschutz und Wohlfahrt ; nach den neuesten Erfahrungen, den einschlägigen Gesetzen und Verordnungen, der einschlägigen Statistik in Deutschland und Oesterreich

    1891  

    Author's details hrsg. von Max Kraft
    Language German
    Dates of publication 1891-9999
    Publisher Spielhagen & Schurich
    Publishing place Wien
    Publishing country XA-AAAT
    Document type Book ; Collection (display volumes)
    HBZ-ID HT006446586
    Database Catalogue ZB MED Medicine, Health

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