LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 683

Search options

  1. Book ; Online: Induction and Maintenance of Long-Term Immunological Memory Following Infection or Vaccination

    Vajdy, Michael / Mantis, Nicholas J. / Krammer, Florian

    2020  

    Keywords Medicine ; Immunology ; immunological memory ; B cell memory ; T cell memory ; vaccination ; adjuvant ; infection
    Size 1 electronic resource (125 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230829
    ISBN 9782889633739 ; 288963373X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  2. Article ; Online: The role of vaccines in the COVID-19 pandemic: what have we learned?

    Krammer, Florian

    Seminars in immunopathology

    2023  

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately 20 million lives. Vaccines were developed quickly, became available in the ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately 20 million lives. Vaccines were developed quickly, became available in the end of 2020, and had a tremendous impact on protection from SARS-CoV-2 mortality but with emerging variants the impact on morbidity was diminished. Here I review what we learned from COVID-19 from a vaccinologist's perspective.
    Language English
    Publishing date 2023-07-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2316828-6
    ISSN 1863-2300 ; 1863-2297
    ISSN (online) 1863-2300
    ISSN 1863-2297
    DOI 10.1007/s00281-023-00996-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: A correlate of protection for SARS-CoV-2 vaccines is urgently needed.

    Krammer, Florian

    Nature medicine

    2021  Volume 27, Issue 7, Page(s) 1147–1148

    MeSH term(s) Antibodies, Viral ; COVID-19 ; COVID-19 Vaccines ; Humans ; SARS-CoV-2 ; Viral Vaccines
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines ; Viral Vaccines
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-021-01432-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Profile of Katalin Karikó and Drew Weissman: 2023 Nobel laureates in Physiology or Medicine.

    Krammer, Florian / Palese, Peter

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Volume 121, Issue 9, Page(s) e2400423121

    MeSH term(s) Medicine ; Nobel Prize ; Physiology
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2400423121
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Correlates of protection from SARS-CoV-2 infection.

    Krammer, Florian

    Lancet (London, England)

    2021  Volume 397, Issue 10283, Page(s) 1421–1423

    MeSH term(s) Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19/immunology ; COVID-19/virology ; Humans ; Immunity, Mucosal ; Reinfection/immunology ; SARS-CoV-2 ; Viral Load
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral
    Language English
    Publishing date 2021-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)00782-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Pandemic Vaccines: How Are We Going to Be Better Prepared Next Time?

    Krammer, Florian

    Med (New York, N.Y.)

    2020  Volume 1, Issue 1, Page(s) 28–32

    Abstract: In response to the SARS-CoV-2 pandemic, we are currently witnessing the fastest vaccine development in history. While these vaccines will now make a significant impact on ending the pandemic, they were needed much earlier. Here I discuss how to ensure ... ...

    Abstract In response to the SARS-CoV-2 pandemic, we are currently witnessing the fastest vaccine development in history. While these vaccines will now make a significant impact on ending the pandemic, they were needed much earlier. Here I discuss how to ensure that vaccines will become available within 3-4 months after a new outbreak.
    MeSH term(s) COVID-19/epidemiology ; COVID-19 Vaccines/therapeutic use ; Humans ; Pandemics/prevention & control ; SARS-CoV-2 ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2020-12-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2666-6340
    ISSN (online) 2666-6340
    DOI 10.1016/j.medj.2020.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: SARS-CoV-2 vaccines in development.

    Krammer, Florian

    Nature

    2020  Volume 586, Issue 7830, Page(s) 516–527

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late 2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To mitigate the effects of the virus on public health, the economy and ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late 2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To mitigate the effects of the virus on public health, the economy and society, a vaccine is urgently needed. Here I review the development of vaccines against SARS-CoV-2. Development was initiated when the genetic sequence of the virus became available in early January 2020, and has moved at an unprecedented speed: a phase I trial started in March 2020 and there are currently more than 180 vaccines at various stages of development. Data from phase I and phase II trials are already available for several vaccine candidates, and many have moved into phase III trials. The data available so far suggest that effective and safe vaccines might become available within months, rather than years.
    MeSH term(s) Animals ; COVID-19 ; COVID-19 Vaccines ; Clinical Trials as Topic ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/virology ; Drug Development ; Drug Industry ; Humans ; Immunity, Mucosal ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; Viral Vaccines/adverse effects ; Viral Vaccines/immunology ; Viral Vaccines/supply & distribution
    Chemical Substances COVID-19 Vaccines ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-09-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-020-2798-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: We need to keep an eye on avian influenza.

    Krammer, Florian / Schultz-Cherry, Stacey

    Nature reviews. Immunology

    2023  Volume 23, Issue 5, Page(s) 267–268

    MeSH term(s) Animals ; Humans ; Influenza in Birds ; Influenza, Human/prevention & control
    Language English
    Publishing date 2023-12-21
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-023-00868-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Variant-adapted COVID-19 booster vaccines.

    Krammer, Florian / Ellebedy, Ali H

    Science (New York, N.Y.)

    2023  Volume 382, Issue 6667, Page(s) 157–159

    Abstract: Current vaccines should be tailored to combat future SARS-CoV-2 variants. ...

    Abstract Current vaccines should be tailored to combat future SARS-CoV-2 variants.
    MeSH term(s) Humans ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology ; Immunization, Secondary ; Vaccine Efficacy
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines
    Language English
    Publishing date 2023-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.adh2712
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: The human antibody response to influenza A virus infection and vaccination.

    Krammer, Florian

    Nature reviews. Immunology

    2019  Volume 19, Issue 6, Page(s) 383–397

    Abstract: The adaptive immune response to influenza virus infection is multifaceted and complex, involving antibody and cellular responses at both systemic and mucosal levels. Immune responses to natural infection with influenza virus in humans are relatively ... ...

    Abstract The adaptive immune response to influenza virus infection is multifaceted and complex, involving antibody and cellular responses at both systemic and mucosal levels. Immune responses to natural infection with influenza virus in humans are relatively broad and long-lived, but influenza viruses can escape from these responses over time owing to their high mutation rates and antigenic flexibility. Vaccines are the best available countermeasure against infection, but vaccine effectiveness is low compared with other viral vaccines, and the induced immune response is narrow and short-lived. Furthermore, inactivated influenza virus vaccines focus on the induction of systemic IgG responses but do not effectively induce mucosal IgA responses. Here, I review the differences between natural infection and vaccination in terms of the antibody responses they induce and how these responses protect against future infection. A better understanding of how natural infection induces broad and long-lived immune responses will be key to developing next-generation influenza virus vaccines.
    MeSH term(s) Adaptive Immunity ; Animals ; Antibodies, Viral/biosynthesis ; Antibodies, Viral/immunology ; Humans ; Immunogenicity, Vaccine ; Influenza A virus/immunology ; Influenza Vaccines/immunology ; Influenza, Human/immunology ; Influenza, Human/prevention & control
    Chemical Substances Antibodies, Viral ; Influenza Vaccines
    Language English
    Publishing date 2019-03-06
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-019-0143-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top