LIVIVO - Search results -

Search results

Result 1 - 10 of total 126

Search options

Article ; Online: The impact of PA/I38 substitutions and PA polymorphisms on the susceptibility of zoonotic influenza A viruses to baloxavir.

Taniguchi, Keiichi / Noshi, Takeshi / Omoto, Shinya / Sato, Akihiko / Shishido, Takao / Matsuno, Keita / Okamatsu, Masatoshi / Krauss, Scott / Webby, Richard J / Sakoda, Yoshihiro / Kida, Hiroshi

Archives of virology

2024 Volume 169, Issue 2, Page(s) 29

Abstract: Genetic reassortment of avian, swine, and human influenza A viruses (IAVs) poses potential pandemic risks. Surveillance is important for influenza pandemic preparedness, but the susceptibility of zoonotic IAVs to the cap-dependent endonuclease inhibitor ... ...

Abstract	Genetic reassortment of avian, swine, and human influenza A viruses (IAVs) poses potential pandemic risks. Surveillance is important for influenza pandemic preparedness, but the susceptibility of zoonotic IAVs to the cap-dependent endonuclease inhibitor baloxavir acid (BXA) has not been thoroughly researched. Although an amino acid substitution at position 38 in the polymerase acidic protein (PA/I38) in seasonal IAVs reduces BXA susceptibility, PA polymorphisms at position 38 are rarely seen in zoonotic IAVs. Here, we examined the impact of PA/I38 substitutions on the BXA susceptibility of recombinant A(H5N1) viruses. PA mutants that harbored I38T, F, and M were 48.2-, 24.0-, and 15.5-fold less susceptible, respectively, to BXA than wild-type A(H5N1) but were susceptible to the neuraminidase inhibitor oseltamivir acid and the RNA polymerase inhibitor favipiravir. PA mutants exhibited significantly impaired replicative fitness in Madin-Darby canine kidney cells at 24 h postinfection. In addition, in order to investigate new genetic markers for BXA susceptibility, we screened geographically and temporally distinct IAVs isolated worldwide from birds and pigs. The results showed that BXA exhibited antiviral activity against avian and swine viruses with similar levels to seasonal isolates. All viruses tested in the study lacked the PA/I38 substitution and were susceptible to BXA. Isolates harboring amino acid polymorphisms at positions 20, 24, and 37, which have been implicated in the binding of BXA to the PA endonuclease domain, were also susceptible to BXA. These results suggest that monitoring of the PA/I38 substitution in animal-derived influenza viruses is important for preparedness against zoonotic influenza virus outbreaks.
MeSH term(s)	Animals ; Dogs ; Humans ; Swine ; Influenza A virus/genetics ; Oxazines/pharmacology ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Influenza A Virus, H5N1 Subtype/genetics ; Thiepins/pharmacology ; Thiepins/therapeutic use ; Influenza, Human ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Orthomyxoviridae/genetics ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Amino Acid Substitution ; Endonucleases/genetics ; Drug Resistance, Viral/genetics ; Dibenzothiepins ; Morpholines ; Pyridones ; Triazines
Chemical Substances	baloxavir (4G86Y4JT3F) ; Oxazines ; Pyridines ; Thiepins ; Antiviral Agents ; Enzyme Inhibitors ; Endonucleases (EC 3.1.-) ; Dibenzothiepins ; Morpholines ; Pyridones ; Triazines
Language	English
Publishing date	2024-01-12
Publishing country	Austria
Document type	Journal Article
ZDB-ID	7491-3
ISSN	1432-8798 ; 0304-8608
ISSN (online)	1432-8798
ISSN	0304-8608
DOI	10.1007/s00705-023-05958-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.110: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Highly pathogenic avian influenza virus H5N2 (clade 2.3.4.4) challenge of mallards age appropriate to the 2015 midwestern poultry outbreak.

Hall, Jeffrey S / Grear, Daniel A / Krauss, Scott / Seiler, J Patrick / Dusek, Robert J / Nashold, Sean W / Webster, Robert G

Influenza and other respiratory viruses

2021 Volume 15, Issue 6, Page(s) 767–777

Abstract: Background: The 2015 highly pathogenic avian influenza virus (HPAIV) H5N2 clade 2.3.4.4 outbreak in upper midwestern U.S. poultry operations was not detected in wild birds to any great degree during the outbreak, despite wild waterfowl being implicated ... ...

Abstract	Background: The 2015 highly pathogenic avian influenza virus (HPAIV) H5N2 clade 2.3.4.4 outbreak in upper midwestern U.S. poultry operations was not detected in wild birds to any great degree during the outbreak, despite wild waterfowl being implicated in the introduction, reassortment, and movement of the virus into North America from Asia. This outbreak led to the demise of over 50 million domestic birds and occurred mainly during the northward spring migration of adult avian populations. Objectives: There have been no experimental examinations of the pathogenesis, transmission, and population impacts of this virus in adult wild waterfowl with varying exposure histories-the most relevant age class. Methods: We captured, housed, and challenged adult wild mallards (Anas platyrhynchos) with HPAIV H5N2 clade 2.3.4.4 and measured viral infection, viral excretion, and transmission to other mallards. Results: All inoculated birds became infected and excreted moderate amounts of virus, primarily orally, for up to 14 days. Cohoused, uninoculated birds also all became infected. Serological status had no effect on susceptibility. There were no obvious clinical signs of disease, and all birds survived to the end of the study (14 days). Conclusions: Based on these results, adult mallards are viable hosts of HPAIV H5N2 regardless of prior exposure history and are capable of transporting the virus over short and long distances. These findings have implications for surveillance efforts. The capture and sampling of wild waterfowl in the spring, when most surveillance programs are not operating, are important to consider in the design of future HPAIV surveillance programs.
MeSH term(s)	Animals ; Disease Outbreaks ; Ducks ; Humans ; Influenza A Virus, H5N2 Subtype/genetics ; Influenza in Birds/epidemiology ; Poultry ; Poultry Diseases/epidemiology
Language	English
Publishing date	2021-07-29
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2274538-5
ISSN	1750-2659 ; 1750-2640
ISSN (online)	1750-2659
ISSN	1750-2640
DOI	10.1111/irv.12886
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6568: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Predicting the next influenza virus.

Krauss, Scott / Webster, Robert G

Science (New York, N.Y.)

2012 Volume 337, Issue 6095, Page(s) 644

MeSH term(s)	Animals ; Birds ; Humans ; Influenza A Virus, H7N3 Subtype/genetics ; Influenza A Virus, H7N3 Subtype/pathogenicity ; Influenza in Birds/epidemiology ; Influenza in Birds/transmission ; Influenza in Birds/virology ; Influenza, Human/transmission ; Influenza, Human/virology ; Population Surveillance ; Poultry
Language	English
Publishing date	2012-08-10
Publishing country	United States
Document type	Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.337.6095.644-a
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 27: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 77: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Host diversity and behavior determine patterns of interspecies transmission and geographic diffusion of avian influenza A subtypes among North American wild reservoir species.

Hicks, Joseph T / Edwards, Kimberly / Qiu, Xueting / Kim, Do-Kyun / Hixson, James E / Krauss, Scott / Webby, Richard J / Webster, Robert G / Bahl, Justin

PLoS pathogens

2022 Volume 18, Issue 4, Page(s) e1009973

Abstract: Wild birds can carry avian influenza viruses (AIV), including those with pandemic or panzootic potential, long distances. Even though AIV has a broad host range, few studies account for host diversity when estimating AIV spread. We analyzed AIV genomic ... ...

Abstract	Wild birds can carry avian influenza viruses (AIV), including those with pandemic or panzootic potential, long distances. Even though AIV has a broad host range, few studies account for host diversity when estimating AIV spread. We analyzed AIV genomic sequences from North American wild birds, including 303 newly sequenced isolates, to estimate interspecies and geographic viral transition patterns among multiple co-circulating subtypes. Our results show high transition rates within Anseriformes and Charadriiformes, but limited transitions between these orders. Patterns of transition between species were positively associated with breeding habitat range overlap, and negatively associated with host genetic distance. Distance between regions (negative correlation) and summer temperature at origin (positive correlation) were strong predictors of transition between locations. Taken together, this study demonstrates that host diversity and ecology can determine evolutionary processes that underlie AIV natural history and spread. Understanding these processes can provide important insights for effective control of AIV.
MeSH term(s)	Animals ; Animals, Wild ; Birds ; Influenza A virus ; Influenza in Birds ; North America/epidemiology
Language	English
Publishing date	2022-04-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2205412-1
ISSN	1553-7374 ; 1553-7374
ISSN (online)	1553-7374
ISSN	1553-7374
DOI	10.1371/journal.ppat.1009973
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: NEUTRALIZING ANTIBODIES TO TYPE A INFLUENZA VIRUSES IN SHOREBIRDS AT DELAWARE BAY, NEW JERSEY, USA.

Bahnson, Charlie S / Poulson, Rebecca L / Krauss, Scott / Webster, Robert G / Stallknecht, David E

Journal of wildlife diseases

2018 Volume 54, Issue 4, Page(s) 708–715

Abstract: Influenza A virus (IAV) infections in shorebirds at Delaware Bay, New Jersey, US, have historically included avian hemagglutinin (HA) subtypes H1-13 and H16. In a given year, infections are characterized by a limited number of HA and neuraminidase ... ...

Abstract	Influenza A virus (IAV) infections in shorebirds at Delaware Bay, New Jersey, US, have historically included avian hemagglutinin (HA) subtypes H1-13 and H16. In a given year, infections are characterized by a limited number of HA and neuraminidase subtypes and a dominant HA subtype that often represents >50% of all isolates. Predominant HA subtypes shift between consecutive years. In addition, infection prevalence is consistently higher in Ruddy Turnstones (RUTU; Arenaria interpres morinella) compared to Red Knots (REKN; Calidris canutus rufa), despite comparable rates of exposure. To investigate a potential immunological basis for this phenomenon, a virus microneutralization assay was used to detect subtype-specific, neutralizing antibodies to H1-H12 in sera collected from RUTUs from 2012-16 and REKNs in 2012, 2013, and 2016. Neutralizing antibodies to one or more subtypes were detected in 36% (222/611) of RUTUs. Prevalence of antibodies to subtypes H6 and H11 remained high throughout the study, and these virus subtypes were isolated every year, suggesting a continual source of exposure. Antibody prevalence was intermediate for most IAV subtypes that were isolated in 2-3 of 5 yr (H1, H3, H5, H9, H10, and H12) but was low for H7 viruses, despite the isolation of this virus subtype in 3 of 5 yr. This suggests a reduced antigenicity of H7 IAVs compared to other subtypes. Antibody prevalence was low for H4 virus that was isolated once, and H2 and H8 viruses that were never isolated. Neutralizing antibodies were detected in 66% (169/257) of REKNs and subtype-specific antibody prevalences were higher in REKNs than RUTUs with few exceptions. The results suggest that population immunity influences which species is infected at Delaware Bay, indicate that IAV dynamics are subtype-dependent, and demonstrate the utility of the microneutralization assay as a supportive tool for field research.
MeSH term(s)	Animals ; Antibodies, Neutralizing ; Antibodies, Viral/blood ; Charadriiformes ; Influenza A virus/immunology ; Influenza in Birds/epidemiology ; Influenza in Birds/immunology ; New Jersey/epidemiology ; Prevalence ; Time Factors
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral
Language	English
Publishing date	2018-05-09
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	410709-3
ISSN	1943-3700 ; 0090-3558
ISSN (online)	1943-3700
ISSN	0090-3558
DOI	10.7589/2017-10-252
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1441: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Avian influenza virus surveillance and wild birds: past and present.

Krauss, Scott / Webster, Robert G

Avian diseases

2010 Volume 54, Issue 1 Suppl, Page(s) 394–398

Abstract: Influenza surveillance in wild birds has established that the aquatic birds of the world are the source of influenza A viruses, which occasionally spread to domestic avian species and to mammals, including humans, and cause mild to severe disease. With ... ...

Abstract	Influenza surveillance in wild birds has established that the aquatic birds of the world are the source of influenza A viruses, which occasionally spread to domestic avian species and to mammals, including humans, and cause mild to severe disease. With the realization that the pandemics of influenza in poultry and people originate from inapparent infections of aquatic birds, including the highly pathogenic H5N1 virus, much more attention has been given to understanding the ecology of influenza in wild aquatic birds. This article deals with the major events establishing the role of wild birds in the natural history of influenza and with some of the unresolved issues. These include 1) whether all H5 and H7 influenza viruses have high pandemic potential, 2) whether avian influenza (AI) is exchanged between Eurasia and the Americas, and 3) whether the highly pathogenic H5N1 AI virus is now being perpetuated in wild birds, one of the most important unresolved issues. Continued surveillance of wild birds for influenza is essential to resolve the many unanswered questions concerning the zoonotic spread of influenza and pandemicity.
MeSH term(s)	Animals ; Animals, Wild ; Birds ; Influenza in Birds/epidemiology ; Population Surveillance
Language	English
Publishing date	2010-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	40871-2
ISSN	1938-4351 ; 0005-2086
ISSN (online)	1938-4351
ISSN	0005-2086
DOI	10.1637/8703-031609-Review.1
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 526: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Influenza A Viruses in Ruddy Turnstones (Arenaria interpres); Connecting Wintering and Migratory Sites with an Ecological Hotspot at Delaware Bay

Poulson, Rebecca / Carter, Deborah / Beville, Shelley / Niles, Lawrence / Dey, Amanda / Minton, Clive / McKenzie, Pamela / Krauss, Scott / Webby, Richard / Webster, Robert / Stallknecht, David E

Viruses. 2020 Oct. 22, v. 12, no. 11

2020

Abstract: Each May for over three decades, avian influenza A viruses (IAVs) have been isolated from shorebirds and gulls (order Charadriiformes) at Delaware Bay (DE Bay), USA, which is a critical stopover site for shorebirds on their spring migration to arctic ... ...

Abstract	Each May for over three decades, avian influenza A viruses (IAVs) have been isolated from shorebirds and gulls (order Charadriiformes) at Delaware Bay (DE Bay), USA, which is a critical stopover site for shorebirds on their spring migration to arctic breeding grounds. At DE Bay, most isolates have been recovered from ruddy turnstones (Arenaria interpres), but it is unknown if this species is involved in either the maintenance or movement of these viruses outside of this site. We collected and tested fecal samples from 2823 ruddy turnstones in Florida and Georgia in the southeastern United States during four winter/spring sample periods—2010, 2011, 2012, and 2013—and during the winters of 2014/2015 and 2015/2016. Twenty-five low pathogenicity IAVs were recovered representing five subtypes (H3N4, H3N8, H5N9, H6N1, and H12N2). Many of these subtypes matched those recovered at DE Bay during the previous year or that year’s migratory cycle, suggesting that IAVs present on these southern wintering areas represent a source of virus introduction to DE Bay via migrating ruddy turnstones. Analyses of all IAV gene segments of H5N9 and H6N1 viruses recovered from ruddy turnstones at DE Bay during May 2012 and from the southeast during the spring of 2012 revealed a high level of genetic relatedness at the nucleotide level, suggesting that migrating ruddy turnstones move IAVs from wintering grounds to the DE Bay ecosystem.
Keywords	Arenaria interpres ; Influenza A virus ; Laridae ; avian influenza ; breeding sites ; ecosystems ; feces ; genes ; genetic relationships ; migratory behavior ; pathogenicity ; spring ; stopover sites ; viruses ; winter ; wintering grounds ; Arctic region ; Delaware Bay ; Florida ; Georgia
Language	English
Dates of publication	2020-1022
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2516098-9
ISSN	1999-4915
ISSN	1999-4915
DOI	10.3390/v12111205
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Global dissemination of influenza A virus is driven by wild bird migration through arctic and subarctic zones

Gass, Jonathon D., Jr / Dusek, Robert J. / Hall, Jeffrey S. / Hallgrimsson, Gunnar Thor / Halldórsson, Halldór Pálmar / Vignisson, Solvi Runar / Ragnarsdottir, Sunna Bjork / Jónsson, Jón Einar / Krauss, Scott / Wong, Sook‐San / Wan, Xiu‐Feng / Akter, Sadia / Sreevatsan, Srinand / Trovão, Nídia S. / Nutter, Felicia B. / Runstadler, Jonathan A. / Hill, Nichola J.

Molecular Ecology. 2023 Jan., v. 32, no. 1 p.198-213

2023

Abstract: Influenza A viruses (IAV) circulate endemically among many wild aquatic bird populations that seasonally migrate between wintering grounds in southern latitudes to breeding ranges along the perimeter of the circumpolar arctic. Arctic and subarctic zones ... ...

Abstract	Influenza A viruses (IAV) circulate endemically among many wild aquatic bird populations that seasonally migrate between wintering grounds in southern latitudes to breeding ranges along the perimeter of the circumpolar arctic. Arctic and subarctic zones are hypothesized to serve as ecologic drivers of the intercontinental movement and reassortment of IAVs due to high densities of disparate populations of long distance migratory and native bird species present during breeding seasons. Iceland is a staging ground that connects the East Atlantic and North Atlantic American flyways, providing a unique study system for characterizing viral flow between eastern and western hemispheres. Using Bayesian phylodynamic analyses, we sought to evaluate the viral connectivity of Iceland to proximal regions and how inter‐species transmission and reassortment dynamics in this region influence the geographic spread of low and highly pathogenic IAVs. Findings demonstrate that IAV movement in the arctic and subarctic reflects wild bird migration around the perimeter of the circumpolar north, favouring short‐distance flights between proximal regions rather than long distance flights over the polar interior. Iceland connects virus movement between mainland Europe and North America, consistent with the westward migration of wild birds from mainland Europe to Northeastern Canada and Greenland. Though virus diffusion rates were similar among avian taxonomic groups in Iceland, gulls play an outsized role as sinks of IAVs from other avian hosts prior to onward migration. These data identify patterns of virus movement in northern latitudes and inform future surveillance strategies related to seasonal and emergent IAVs with potential public health concern.
Keywords	Bayesian theory ; Influenza A virus ; ecology ; influenza ; migratory behavior ; monitoring ; public health ; viruses ; water birds ; wild birds ; Arctic region ; Canada ; Greenland ; Iceland
Language	English
Dates of publication	2023-01
Size	p. 198-213.
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	1126687-9
ISSN	1365-294X ; 0962-1083
ISSN (online)	1365-294X
ISSN	0962-1083
DOI	10.1111/mec.16738
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 2005/723: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Global dissemination of influenza A virus is driven by wild bird migration through arctic and subarctic zones.

Gass, Jonathon D / Dusek, Robert J / Hall, Jeffrey S / Hallgrimsson, Gunnar Thor / Halldórsson, Halldór Pálmar / Vignisson, Solvi Runar / Ragnarsdottir, Sunna Bjork / Jónsson, Jón Einar / Krauss, Scott / Wong, Sook-San / Wan, Xiu-Feng / Akter, Sadia / Sreevatsan, Srinand / Trovão, Nídia S / Nutter, Felicia B / Runstadler, Jonathan A / Hill, Nichola J

Molecular ecology

2022 Volume 32, Issue 1, Page(s) 198–213

Abstract	Influenza A viruses (IAV) circulate endemically among many wild aquatic bird populations that seasonally migrate between wintering grounds in southern latitudes to breeding ranges along the perimeter of the circumpolar arctic. Arctic and subarctic zones are hypothesized to serve as ecologic drivers of the intercontinental movement and reassortment of IAVs due to high densities of disparate populations of long distance migratory and native bird species present during breeding seasons. Iceland is a staging ground that connects the East Atlantic and North Atlantic American flyways, providing a unique study system for characterizing viral flow between eastern and western hemispheres. Using Bayesian phylodynamic analyses, we sought to evaluate the viral connectivity of Iceland to proximal regions and how inter-species transmission and reassortment dynamics in this region influence the geographic spread of low and highly pathogenic IAVs. Findings demonstrate that IAV movement in the arctic and subarctic reflects wild bird migration around the perimeter of the circumpolar north, favouring short-distance flights between proximal regions rather than long distance flights over the polar interior. Iceland connects virus movement between mainland Europe and North America, consistent with the westward migration of wild birds from mainland Europe to Northeastern Canada and Greenland. Though virus diffusion rates were similar among avian taxonomic groups in Iceland, gulls play an outsized role as sinks of IAVs from other avian hosts prior to onward migration. These data identify patterns of virus movement in northern latitudes and inform future surveillance strategies related to seasonal and emergent IAVs with potential public health concern.
MeSH term(s)	Animals ; Influenza A virus/genetics ; Influenza in Birds/epidemiology ; Bayes Theorem ; Animals, Wild ; Birds ; Animal Migration ; Phylogeny
Language	English
Publishing date	2022-10-26
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1126687-9
ISSN	1365-294X ; 0962-1083
ISSN (online)	1365-294X
ISSN	0962-1083
DOI	10.1111/mec.16738
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 2005/723: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Avian Influenza Virus Surveillance and Wild Birds: Past and Present

Krauss, Scott / Webster, Robert G

Avian diseases. 2010 Mar., v. 54, suppl. 1

2010

Abstract	Influenza surveillance in wild birds has established that the aquatic birds of the world are the source of influenza A viruses, which occasionally spread to domestic avian species and to mammals, including humans, and cause mild to severe disease. With the realization that the pandemics of influenza in poultry and people originate from inapparent infections of aquatic birds, including the highly pathogenic H5N1 virus, much more attention has been given to understanding the ecology of influenza in wild aquatic birds. This article deals with the major events establishing the role of wild birds in the natural history of influenza and with some of the unresolved issues. These include 1) whether all H5 and H7 influenza viruses have high pandemic potential, 2) whether avian influenza (AI) is exchanged between Eurasia and the Americas, and 3) whether the highly pathogenic H5N1 AI virus is now being perpetuated in wild birds, one of the most important unresolved issues. Continued surveillance of wild birds for influenza is essential to resolve the many unanswered questions concerning the zoonotic spread of influenza and pandemicity.
Keywords	Influenza A virus ; vertebrate viruses ; pathogenicity ; wild birds ; disease surveillance ; disease control ; history ; waterfowl ; disease reservoirs ; virus transmission ; disease outbreaks ; signs and symptoms (animals and humans) ; geographical distribution ; zoonoses
Language	English
Dates of publication	2010-03
Size	p. 394-398.
Document type	Article
Note	Summary in Spanish. ; Paper presented at the 7th International Symposium on Avian Influenza, held on April 5-8, 2009, in Athens, Georgia.
ZDB-ID	40871-2
ISSN	1938-4351 ; 0005-2086
ISSN (online)	1938-4351
ISSN	0005-2086
DOI	10.1637/8703-031609-Review.1
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.B 526: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito