LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Provins as an example of a “live museum”

    Kuśnierz-Krupa Dominika

    E3S Web of Conferences, Vol 49, p

    2018  Volume 00065

    Abstract: The article concerns the history, revalorisation and accessibility of the cultural heritage in the historic town of Provins, located to the southwest of Paris. The town was founded in the early medieval period, and in the 12th and 13th century it was one ...

    Abstract The article concerns the history, revalorisation and accessibility of the cultural heritage in the historic town of Provins, located to the southwest of Paris. The town was founded in the early medieval period, and in the 12th and 13th century it was one of the most prominent fair towns in Champagne. Many valuable monuments of that period have survived until the present time, such as the urban layout, the defensive walls, the Cesar tower supposedly relating to the legendary origins of the town dating back to the Roman period, churches and relics of residential buildings. In 2001, the above mentioned buildings were appreciated and distinguished by the UNESCO Committee which inscribed Provins in the World Heritage List. This distinction is not merely a matter of pride for the local authorities, but also an obligation to properly maintain the historic heritage, to revalorise it constantly and to educate the community regarding the protection of the town heritage. It must be stated that the authorities perfectly fulfil their responsibilities, which is worth presenting in this article to set an example of proper cultural heritage management for other historic towns.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Protection issues in selected European historic towns and their contemporary development

    Kuśnierz-Krupa Dominika

    E3S Web of Conferences, Vol 45, p

    2018  Volume 00043

    Abstract: The presented article is aimed at presenting a few selected examples of small European historic towns whose properly protected cultural heritage considerably contributes to their development in the 21st century. The issue of protection and revalorisation ...

    Abstract The presented article is aimed at presenting a few selected examples of small European historic towns whose properly protected cultural heritage considerably contributes to their development in the 21st century. The issue of protection and revalorisation of Polish towns, particularly the smaller ones, is relevant nowadays. Historic heritage seems to be a burden for local authorities and residents because very often they are not aware of how it could contribute to the multidirectional development of their towns. The local inhabitants and authorities of small historic towns in Western European countries respect their heritage much more than Poles, as they associate it with the idea of sustainable development, “place specificity”, and finally, with an opportunity for development, treating cultural heritage as a basis for economic progress and building new and modern infrastructure. It is worth drawing attention here, that sustainable development denotes changing the reality in such a way that the development would optimally satisfy the needs of modern man, without violating the needs of future generations. The testimony to the potential of the cultural heritage of historic towns in the context of their modern development is borne by the towns whose authorities and inhabitants were able to utilise their past for building their future. As examples one could name here French (e.g. Auxerre, Provins,) or German towns (e.g. Heppenheim, Lorsch).
    Keywords Environmental sciences ; GE1-350
    Subject code 710
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Impact of COVID-19 Pandemic on the Use of Antidepressant and Antianxiety Pharmaceuticals as Well as Sick Leave in Poland.

    Krupa, Dominika / Czech, Marcin / Pinkas, Jarosław / Mosiołek, Anna

    International journal of environmental research and public health

    2022  Volume 19, Issue 4

    Abstract: The COVID-19 pandemic caused a major upheaval to the lives of people and placed a strain on societal mental health. The aim of this research is to estimate the impact of the pandemic on the mental condition of the Polish population measured through the ... ...

    Abstract The COVID-19 pandemic caused a major upheaval to the lives of people and placed a strain on societal mental health. The aim of this research is to estimate the impact of the pandemic on the mental condition of the Polish population measured through the consumption of relevant medication and medical leave of absence from the workplace.
    Methods: We analyzed national-level data on the consumption of pharmaceuticals used in clinical practice in Poland in the treatment of depression and anxiety alongside medical absence in the workplace using the Interrupted Time Series model to estimate the significance of the pandemic.
    Results: We found no significant change regarding the consumption of pharmaceuticals with the development of the pandemic. Conversely, medical leaves of absence for psychiatric reasons increased significantly with the onset of COVID-19. The influence was strongest in the diagnosis of anxiety or reaction to severe stress and weakest in recurrent depression.
    Conclusion: The pandemic had a significant influence on the ability to work for psychiatric patients in Poland but did not change pharmaceutical use. Physicians should consider the mental health of patients impacted by the anti-epidemic measures. Further study is needed to fully understand the long-term impact of the pandemic on mental health in Poland.
    MeSH term(s) Antidepressive Agents/therapeutic use ; Anxiety/drug therapy ; Anxiety/epidemiology ; Anxiety/psychology ; COVID-19/drug therapy ; COVID-19/epidemiology ; Depression/drug therapy ; Depression/epidemiology ; Depression/psychology ; Humans ; Pandemics ; Pharmaceutical Preparations ; Poland/epidemiology ; SARS-CoV-2 ; Sick Leave
    Chemical Substances Antidepressive Agents ; Pharmaceutical Preparations
    Language English
    Publishing date 2022-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19042135
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Real World Evidence on the Effectiveness of Nusinersen within the National Program to Treat Spinal Muscular Atrophy in Poland.

    Krupa, Dominika / Czech, Marcin / Chudzyńska, Ewa / Koń, Beata / Kostera-Pruszczyk, Anna

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 10

    Abstract: Background: Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease resulting in children's mortality and disability. Nusinersen is available to all SMA patients in Poland since 2019.: Aim: To compare mortality or disease progression to ...

    Abstract Background: Spinal muscular atrophy (SMA) is a debilitating neuromuscular disease resulting in children's mortality and disability. Nusinersen is available to all SMA patients in Poland since 2019.
    Aim: To compare mortality or disease progression to mechanical ventilation in two patient cohorts before and after the program's introduction. Additionally, to describe the patient population treated with nusinersen and costs incurred by the public payer.
    Methods: We used the National Health Fund (NHF) database to identify patients born in either 2014 or 2019, who received at least two health services with an ICD10 G12 diagnosis. Outcomes were time to event: death or first mechanical ventilation. We identified all benefits received by nusinersen-treated patients, between 1 January 2019 and 31 May 2022.
    Results: Children with SMA born in 2019 had significantly lower mortality in the first years of their lives than children born in 2014. Approximately 875 patients (all age groups) were treated with nusinersen in the analysis period. The cost of causal drugs in this period amounted to €51.4 million. The cost of healthcare benefits amounted to €14.9 million.
    Conclusions: The drug program to treat SMA improved patient care in Poland. The NHF database was a reliable source to monitor resource-intensive therapies' costs, demography, and selected patient outcomes.
    Language English
    Publishing date 2023-05-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11101515
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: The Potential to Reduce Patient Co-Payment and the Public Payer Spending in Poland through an Optimised Implementation of the Generic Substitution: The Win-Win Scenario Suggested by the Real-World Big Data Analysis.

    Kardas, Przemysław / Lichwierowicz, Aneta / Urbański, Filip / Szadkowska-Opasiak, Beata / Karasiewicz, Ewa / Lewek, Paweł / Krupa, Dominika / Czech, Marcin

    Pharmaceutics

    2021  Volume 13, Issue 8

    Abstract: High medication costs are one of the major barriers to patient adherence. Medication affordability might be improved by generic substitution. The aim of this study was to assess the effectiveness of the implementation of generic substitution mechanisms ... ...

    Abstract High medication costs are one of the major barriers to patient adherence. Medication affordability might be improved by generic substitution. The aim of this study was to assess the effectiveness of the implementation of generic substitution mechanisms in Poland. This was a retrospective analysis of nationwide real-world big data corresponding to dispensation of metformin preparations in 2019 in Poland. Relevant prescription and dispensation data were compared to assess the prevalence of generic substitution and its economic consequences. Among the 1,135,863 e-prescriptions analysed, a generic substitution was found in only 4.81% of the packs dispensed, based on e-prescriptions issued for metformin under its originator version and 2.73% under generic drugs. It is estimated that if these values were applied to the total Polish drug market, patients could lose the opportunity to lower their co-payment by 15.91% and the national payer to reduce its reimbursement expenditures by 8.31%. Our results point at the suboptimal implementation of generic substitution in Poland. Therefore, relevant actions need to be taken in order to maximise the benefits provided by this mechanism. It could not only lead to the win-win scenario in which both patients and the national payer are secured substantial savings, but it could also have a positive impact on patient adherence.
    Language English
    Publishing date 2021-07-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13081165
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Residual symptoms and disease burden among patients with rheumatoid arthritis in remission or low disease activity: a systematic literature review.

    Ishida, Masato / Kuroiwa, Yuki / Yoshida, Emiko / Sato, Masayo / Krupa, Dominika / Henry, Nathaniel / Ikeda, Kei / Kaneko, Yuko

    Modern rheumatology

    2018  Volume 28, Issue 5, Page(s) 789–799

    Abstract: Objectives: To identify, describe and summarize evidence on residual symptoms and disease burdens in rheumatoid arthritis (RA) patients qualified as being in remission or low disease activity (LDA).: Methods: A systematic literature review (SLR) was ... ...

    Abstract Objectives: To identify, describe and summarize evidence on residual symptoms and disease burdens in rheumatoid arthritis (RA) patients qualified as being in remission or low disease activity (LDA).
    Methods: A systematic literature review (SLR) was conducted according to Cochrane collaboration guidelines. The population of interest was adult patients with RA in remission or LDA. The reported outcomes of interest were any symptoms or burdens.
    Results: Fifty-one publications were identified through an eDatabase search. Together with 17 articles found through other sources, 68 were included for full text review. The most commonly reported residual symptoms were pain (number of studies = 25), fatigue (n = 21) and morning stiffness (n = 5). Reported disease burdens included mental health (n = 15), sleep disturbances (n = 7) and work productivity (n = 5), impairment in quality of life (n = 21), and functional disability (n = 34). Substantial residual symptoms and disease burdens were found to be present in patients in remission or LDA.
    Conclusion: This is the first SLR to investigate residual symptoms and disease burdens in RA patients in remission or LDA. The results indicate that despite achieving conventional clinical targets, the disease continues to affect patients, suggesting the existence of unmet need under the current treatment paradigm.
    MeSH term(s) Adult ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Fatigue/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Pain/epidemiology ; Quality of Life ; Remission Induction
    Chemical Substances Antirheumatic Agents
    Language English
    Publishing date 2018-01-11
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2078157-X
    ISSN 1439-7609 ; 1439-7595
    ISSN (online) 1439-7609
    ISSN 1439-7595
    DOI 10.1080/14397595.2017.1416940
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2982: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top