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  1. Article ; Online: Goats diagnosed with neoplasia display variability in clinical presentations, treatments, and outcomes.

    Krus, Catherine B / Mullins, Caitlyn / Oman, Rachel

    Journal of the American Veterinary Medical Association

    2023  Volume 261, Issue 5, Page(s) 661–667

    Abstract: Objective: To describe clinical presentation, treatment, and short- and long-term outcomes of goats diagnosed with neoplasia.: Animals: 46 goats with a definitive diagnosis of ≥ 1 neoplastic process admitted over a 15-year period.: Procedures: ... ...

    Abstract Objective: To describe clinical presentation, treatment, and short- and long-term outcomes of goats diagnosed with neoplasia.
    Animals: 46 goats with a definitive diagnosis of ≥ 1 neoplastic process admitted over a 15-year period.
    Procedures: Medical records for all goats admitted to the Colorado State University Veterinary Teaching Hospital over a 15-year period were reviewed to identify animals diagnosed with neoplasia. Signalment, presenting complaint, duration of clinical signs, diagnostic testing, treatment, and short-term outcomes were recorded. When available, long-term follow-up data were collected via email or telephone interview with owners.
    Results: 46 goats with 58 neoplasms were identified. The prevalence of neoplasia within the study population was 3.2%. The most commonly diagnosed neoplasms were squamous cell carcinoma, thymoma, and mammary carcinoma. The Saanen breed was the most common breed noted in the study population. Evidence of metastasis was found in 7% of the goats. Long-term follow-up was available in 5 goats with mammary neoplasia that underwent bilateral mastectomy. No evidence of mass regrowth or metastasis was noted in any of the goats 5 to 34 months postoperatively.
    Clinical relevance: Goats are increasingly treated as companion rather than strictly production animals, making it important for veterinarians to provide more evidence-based and advanced clinical care. This study provided a clinical overview of presentation, treatment, and outcome for goats diagnosed with neoplasia and highlighted the challenges associated with the wide variety of neoplastic processes affecting goats.
    MeSH term(s) Animals ; Goats/surgery ; Hospitals, Animal ; Mastectomy/veterinary ; Hospitals, Teaching ; Thymus Neoplasms/veterinary ; Retrospective Studies ; Goat Diseases/diagnosis ; Goat Diseases/epidemiology ; Goat Diseases/therapy
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.22.11.0530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Yersinia pseudotuberculosis

    Krus, Catherine B / Patino, Cristian / Barrington, George M / Burbick, Claire

    The Canadian veterinary journal = La revue veterinaire canadienne

    2023  Volume 65, Issue 1, Page(s) 37–41

    Abstract: A 6-year-old female huacaya alpaca was referred to the clinic for evaluation with a 1-month history of rapid weight loss, inappetence, lethargy, and severe leukocytosis refractory to medical management. Physical examination revealed a body condition ... ...

    Abstract A 6-year-old female huacaya alpaca was referred to the clinic for evaluation with a 1-month history of rapid weight loss, inappetence, lethargy, and severe leukocytosis refractory to medical management. Physical examination revealed a body condition score of 1 out of 5 and a large, firm structure palpable in the right caudoventral abdomen. Abdominal ultrasonographic examination revealed 3 masses with hyperechoic, swirling centers. The largest mass measured 15 cm in diameter with a 2-centimeter capsule, and extended from right of midline into the left inguinal region. Transrectal ultrasonography identified a small uterus and clear delineation between the abdominal masses. Complete blood (cell) count findings were consistent with marked systemic inflammation. Based on initial examination and laboratory findings, exploratory laparotomy was elected. Multiple mesenteric masses strongly adhered to the jejunum were observed within the abdomen. Due to the inoperable conditions and the poor long-term prognosis, the alpaca was euthanized under general anesthesia. Bacterial culture of fluid aspirated from the largest mass revealed
    MeSH term(s) Female ; Animals ; Yersinia pseudotuberculosis ; Camelids, New World ; Leukocytosis/veterinary ; Laparotomy/veterinary
    Language English
    Publishing date 2023-12-18
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 41603-4
    ISSN 0008-5286
    ISSN 0008-5286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Abnormal behavior, and whole-body tremors in a two-year-old Tennessee Fainting Goat cross wether.

    Migliorisi, Alessandro / Acutt, Elizabeth V / Krus, Catherine / Simpson, Katharine M

    Journal of the American Veterinary Medical Association

    2023  Volume 261, Issue 4, Page(s) 573–575

    MeSH term(s) Male ; Animals ; Tennessee ; Goats ; Tremor/veterinary ; Syncope/veterinary ; Goat Diseases/diagnosis
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.22.11.0501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A comparison of Mini-FLOTAC and McMaster techniques, overdispersion and prevalence of parasites in naturally infected North American bison (

    Johnson, William L / Reynolds, Samantha / Adkins, Colton L / Wehus-Tow, Bradly / Brennan, Jameson / Krus, Catherine B / Buttke, Danielle / Martin, Jeff M / Jesudoss Chelladurai, Jeba R J

    Current research in parasitology & vector-borne diseases

    2022  Volume 2, Page(s) 100103

    Abstract: Several quantitative diagnostic techniques are available to estimate gastrointestinal parasite counts in the feces of ruminants. Comparing egg and oocyst magnitudes in naturally infected samples has been a recommended approach to rank fecal techniques. ... ...

    Abstract Several quantitative diagnostic techniques are available to estimate gastrointestinal parasite counts in the feces of ruminants. Comparing egg and oocyst magnitudes in naturally infected samples has been a recommended approach to rank fecal techniques. In this study, we compared the Mini-FLOTAC (sensitivity of 5 eggs per gram (EPG)/oocysts per gram (OPG)) and different averaged replicates of the modified McMaster techniques (sensitivity of 33.33 EPG/OPG) in 387 fecal samples from 10 herds of naturally infected North American bison in the Central Great Plains region of the USA. Both techniques were performed with fecal slurries homogenized in a fill-FLOTAC device. In the study population, prevalence of strongyle eggs,
    Language English
    Publishing date 2022-11-08
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-114X
    ISSN (online) 2667-114X
    DOI 10.1016/j.crpvbd.2022.100103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cardiovascular resistance to thrombosis in 13-lined ground squirrels.

    Bonis, Alison / Anderson, Leah / Talhouarne, Gaëlle / Schueller, Emily / Unke, Jenna / Krus, Catherine / Stokka, Jordan / Koepke, Anna / Lehrer, Brittany / Schuh, Anthony / Andersen, Jeremiah J / Cooper, Scott

    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology

    2018  Volume 189, Issue 1, Page(s) 167–177

    Abstract: 13-lined ground squirrels (Ictidomys tridecemlineatus) enter hibernation as a survival strategy during extreme environmental conditions. Typical ground squirrel hibernation is characterized by prolonged periods of torpor with significantly reduced heart ... ...

    Abstract 13-lined ground squirrels (Ictidomys tridecemlineatus) enter hibernation as a survival strategy during extreme environmental conditions. Typical ground squirrel hibernation is characterized by prolonged periods of torpor with significantly reduced heart rate, blood pressure, and blood flow, interrupted every few weeks by brief interbout arousals (IBA) during which blood flow fluctuates dramatically. These physiological conditions should increase the risk of stasis-induced blood clots and myocardial ischemia. However, ground squirrels have adapted to survive repeated bouts of torpor and IBA without forming lethal blood clots or sustaining lethal ischemic myocardial damage. The purpose of this study was to determine if ground squirrels are resistant to thrombosis and myocardial ischemia during hibernation. Blood markers of coagulation, fibrinolysis, thrombosis, and ischemia, as well as histological markers of myocardial ischemia were measured throughout the annual hibernation cycle. Hibernating ground squirrels were also treated with isoprenaline to induce myocardial ischemia. Thrombin-antithrombin complex levels were significantly reduced (p < 0.05) during hibernation, while D-dimer level remained unchanged throughout the annual cycle, both consistent with an antithrombotic state. During torpor, the ground squirrels were in a hyperfibrinolytic state with an elevated ratio of tissue plasminogen activator complexed with plasminogen activator inhibitor to total plasminogen activator inhibitor (p < 0.05). Histological markers of myocardial ischemia were reversibly elevated during hibernation with no increase in markers of myocardial cell death in the blood. These data suggest that ground squirrels do not form major blood clots during hibernation through suppression of coagulation and a hyperfibrinolytic state. These animals also demonstrate myocardial resistance to ischemia.
    MeSH term(s) Animals ; Antithrombins/metabolism ; Blood Coagulation/physiology ; Myocardial Ischemia/pathology ; Myocardium/pathology ; Plasminogen Activator Inhibitor 1/blood ; Plasminogen Activator Inhibitor 1/genetics ; Sciuridae/blood ; Sciuridae/physiology ; Thrombin/metabolism ; Thrombosis ; Tissue Plasminogen Activator/blood ; Torpor/physiology ; Troponin T/blood
    Chemical Substances Antithrombins ; Plasminogen Activator Inhibitor 1 ; Troponin T ; Thrombin (EC 3.4.21.5) ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2018-10-13
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 231245-1
    ISSN 1432-136X ; 0174-1578
    ISSN (online) 1432-136X
    ISSN 0174-1578
    DOI 10.1007/s00360-018-1186-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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