LIVIVO - Search results -

Search results

Result 1 - 9 of total 9

Search options

Article: The in-patient colonoscopy: a difficult endeavor.

Enns, Robert / Krygier, Darin

Canadian journal of gastroenterology = Journal canadien de gastroenterologie

2008 Volume 22, Issue 11, Page(s) 900–902

MeSH term(s)	Colonic Diseases/diagnosis ; Colonoscopy/methods ; Diagnosis, Differential ; Humans ; Inpatients ; Patient Selection ; Reproducibility of Results
Language	English
Publishing date	2008-08-22
Publishing country	Canada
Document type	Journal Article ; Review
ZDB-ID	639439-5
ISSN	1916-7237 ; 0835-7900
ISSN (online)	1916-7237
ISSN	0835-7900
DOI	10.1155/2008/826271
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: The inpatient colonoscopy: a worthwhile endeavour.

Krygier, Darin / Enns, Robert

Canadian journal of gastroenterology = Journal canadien de gastroenterologie

2008 Volume 22, Issue 12, Page(s) 977–979

MeSH term(s)	Appointments and Schedules ; Colonoscopy/methods ; Hospitalization ; Humans ; Inpatients ; Preoperative Care
Language	English
Publishing date	2008-09-24
Publishing country	Canada
Document type	Journal Article
ZDB-ID	639439-5
ISSN	1916-7237 ; 0835-7900
ISSN (online)	1916-7237
ISSN	0835-7900
DOI	10.1155/2008/576987
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: How to manage difficult Crohn's disease: optimum delivery of anti-TNFs.

Krygier, Darin S / Ko, Hin Hin / Bressler, Brian

Expert review of gastroenterology & hepatology

2009 Volume 3, Issue 4, Page(s) 407–415

Abstract: Crohn's disease is a chronic inflammatory condition that can involve any portion of the GI tract, leading to disabling symptoms and complications. Standard treatment with 5-aminosalicylic acid, antibiotics, corticosteroids and immunosuppressives has ... ...

Abstract	Crohn's disease is a chronic inflammatory condition that can involve any portion of the GI tract, leading to disabling symptoms and complications. Standard treatment with 5-aminosalicylic acid, antibiotics, corticosteroids and immunosuppressives has limited efficacy and is associated with serious potential adverse events. The anti-TNF-alpha agents are effective in the induction and maintenance of remission in luminal and fistulizing Crohn's disease. Recent evidence suggests that early treatment with anti-TNF agents and immunosuppressives may alter the natural history of the disease and prevent late complications. In those patients who have lost response to, or are intolerant of, a single anti-TNF agent, increasing the dose of the medication or switching to alternate biologic agents, such as another anti-TNF drug or natalizumab, have been shown to be effective treatments.
MeSH term(s)	Adalimumab ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/adverse effects ; Anti-Inflammatory Agents/therapeutic use ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized ; Certolizumab Pegol ; Crohn Disease/drug therapy ; Crohn Disease/immunology ; Crohn Disease/pathology ; Drug Resistance ; Drug Therapy, Combination ; Gastrointestinal Agents/administration & dosage ; Gastrointestinal Agents/adverse effects ; Gastrointestinal Agents/therapeutic use ; Humans ; Immunoglobulin Fab Fragments/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Infliximab ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Polyethylene Glycols/therapeutic use ; Treatment Outcome ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Wound Healing/drug effects
Chemical Substances	Anti-Inflammatory Agents ; Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Gastrointestinal Agents ; Immunoglobulin Fab Fragments ; Immunosuppressive Agents ; Tumor Necrosis Factor-alpha ; Polyethylene Glycols (30IQX730WE) ; Infliximab (B72HH48FLU) ; Adalimumab (FYS6T7F842) ; Certolizumab Pegol (UMD07X179E)
Language	English
Publishing date	2009-08
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2481021-6
ISSN	1747-4132 ; 1747-4124
ISSN (online)	1747-4132
ISSN	1747-4124
DOI	10.1586/egh.09.25
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6978: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Clozapine-induced fatal fulminant hepatic failure: a case report.

Chang, Albert / Krygier, Darin S / Chatur, Nazira / Yoshida, Eric M

Canadian journal of gastroenterology = Journal canadien de gastroenterologie

2009 Volume 23, Issue 5, Page(s) 376–378

Abstract: Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in a person who previously had a normal liver or had wellcompensated liver disease. The potential causes of ... ...

Abstract	Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in a person who previously had a normal liver or had wellcompensated liver disease. The potential causes of FHF are numerous, but viral or toxin-induced hepatitis are the most common. Clozapineinduced hepatotoxicity has rarely been reported in the literature, occurs via an unknown mechanism and results in liver biochemical abnormalities that are usually of no clinical significance. In approximately 30% to 50% of patients treated with clozapine, there is an asymptomatic rise in serum aminotransaminase levels; however, there are no current guidelines for routine monitoring of liver function tests and liver enzymes during its use. Fatal fulminant hepatitis has only been reported in three patients receiving clozapine. A case of fatal FHF that occurred in a schizophrenic woman who began clozapine therapy shortly before her illness developed is described.
MeSH term(s)	Antipsychotic Agents/adverse effects ; Clozapine/adverse effects ; Diagnosis, Differential ; Fatal Outcome ; Female ; Humans ; Liver Failure, Acute/chemically induced ; Liver Failure, Acute/diagnosis ; Middle Aged ; Schizophrenia, Paranoid/drug therapy
Chemical Substances	Antipsychotic Agents ; Clozapine (J60AR2IKIC)
Language	English
Publishing date	2009-05-18
Publishing country	Canada
Document type	Case Reports ; Journal Article
ZDB-ID	639439-5
ISSN	1916-7237 ; 0835-7900
ISSN (online)	1916-7237
ISSN	0835-7900
DOI	10.1155/2009/503916
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: The impact of patient education on the quality of inpatient bowel preparation for colonoscopy.

Rosenfeld, Greg / Krygier, Darin / Enns, Robert A / Singham, Janakie / Wiesinger, Holly / Bressler, Brian

Canadian journal of gastroenterology = Journal canadien de gastroenterologie

2010 Volume 24, Issue 9, Page(s) 543–546

Abstract: Background: For patients requiring colonoscopy while admitted to hospital, achieving adequate cleansing of the colon is often difficult.: Objectives: To assess the impact of patient education, in the form of both counselling and written instructions, ...

Abstract	Background: For patients requiring colonoscopy while admitted to hospital, achieving adequate cleansing of the colon is often difficult. Objectives: To assess the impact of patient education, in the form of both counselling and written instructions, on bowel cleanliness at colonoscopy. Methods: A total of 38 inpatients at a tertiary care hospital in Vancouver, British Columbia, who were referred to the gastroenterology service for colonoscopy were enrolled in the present study. Sixteen patients were randomly assigned to the intervention group, while 22 patients comprised the control group. Both groups received a clear liquid diet and 4 L of a commercially available bowel preparation. The intervention group also received a brief counselling session and written instructions outlining the methods and rationale for bowel preparation before colonoscopy. Bowel cleanliness was assessed by the endoscopist using a five-point rating scale. Results: The two groups were similar with respect to demographics, the indication for colonoscopy and findings at colonoscopy. The median bowel cleanliness scores in the control group and the enhanced-instruction group were 3.0 and 2.0, respectively (P=0.001). Conclusion: Patient counselling and written instructions are inexpensive, safe and simple interventions. Such interventions are an effective means of optimizing colonoscopy preparation in the inpatient setting.
MeSH term(s)	Aged ; Cathartics/administration & dosage ; Colonoscopy/methods ; Directive Counseling/methods ; Female ; Humans ; Male ; Patient Education as Topic/methods
Chemical Substances	Cathartics
Language	English
Publishing date	2010-11-30
Publishing country	Canada
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	639439-5
ISSN	1916-7237 ; 0835-7900
ISSN (online)	1916-7237
ISSN	0835-7900
DOI	10.1155/2010/718628
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: The Soma of RPeD1 must be present for long-term memory formation of associative learning in Lymnaea.

Scheibenstock, Andi / Krygier, Darin / Haque, Zara / Syed, Naweed / Lukowiak, Ken

Journal of neurophysiology

2002 Volume 88, Issue 4, Page(s) 1584–1591

Abstract: The cellular basis of long-term memory (LTM) storage is not completely known. We have developed a preparation where we are able to specify that a single identified neuron, Right Pedal Dorsal 1 (RPeD1), is a site of LTM formation of associative learning ... ...

Abstract	The cellular basis of long-term memory (LTM) storage is not completely known. We have developed a preparation where we are able to specify that a single identified neuron, Right Pedal Dorsal 1 (RPeD1), is a site of LTM formation of associative learning in the pond snail, Lymnaea stagnalis. We demonstrated this by ablating the soma of the neuron but leaving behind its functional primary neurite, as evidenced by electrophysiological and behavioral analyses. The soma-less RPeD1 neurite continues to be a necessary participant in the mediation of aerial respiratory behavior, associative learning, and intermediate-term memory (ITM); however, LTM cannot be formed. However, if RPeD1's soma is ablated after LTM consolidation has occurred, LTM can still be accessed. Thus the soma of RPeD1 is a site of LTM formation.
MeSH term(s)	Animals ; Association Learning/physiology ; Conditioning, Operant/physiology ; Denervation ; Lymnaea ; Memory/physiology ; Neurites/physiology ; Neurons/physiology ; Neurons/ultrastructure ; Respiration
Language	English
Publishing date	2002-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80161-6
ISSN	1522-1598 ; 0022-3077
ISSN (online)	1522-1598
ISSN	0022-3077
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.224: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Parvovirus B19 induced hepatic failure in an adult requiring liver transplantation.

Krygier, Darin S / Steinbrecher, Urs P / Petric, Martin / Erb, Siegfried R / Chung, Stephen W / Scudamore, Charles H / Buczkowski, Andrzej K / Yoshida, Eric M

World journal of gastroenterology

2009 Volume 15, Issue 32, Page(s) 4067–4069

Abstract: Parvovirus B19 induced acute hepatitis and hepatic failure have been previously reported, mainly in children. Very few cases of parvovirus induced hepatic failure have been reported in adults and fewer still have required liver transplantation. We report ...

Abstract	Parvovirus B19 induced acute hepatitis and hepatic failure have been previously reported, mainly in children. Very few cases of parvovirus induced hepatic failure have been reported in adults and fewer still have required liver transplantation. We report the case of a 55-year-old immunocompetent woman who developed fulminant hepatic failure after acute infection with Parvovirus B19 who subsequently underwent orthotopic liver transplantation. This is believed to be the first reported case in the literature in which an adult patient with fulminant hepatic failure associated with acute parvovirus B19 infection and without hematologic abnormalities has been identified prior to undergoing liver transplantation. This case suggests that Parvovirus B19 induced liver disease can affect adults, can occur in the absence of hematologic abnormalities and can be severe enough to require liver transplantation.
MeSH term(s)	Acute Disease ; DNA, Viral/metabolism ; Female ; Hepatitis/therapy ; Hepatitis/virology ; Humans ; Liver Failure, Acute/therapy ; Liver Failure, Acute/virology ; Liver Transplantation/methods ; Middle Aged ; Parvoviridae Infections/therapy ; Parvoviridae Infections/virology ; Parvovirus B19, Human/metabolism ; Polymerase Chain Reaction ; Treatment Outcome
Chemical Substances	DNA, Viral
Language	English
Publishing date	2009-08-25
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.15.4067
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6039: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: The use of budesonide in the treatment of autoimmune hepatitis in Canada.

Zandieh, Iman / Krygier, Darin / Wong, Victor / Howard, John / Worobetz, Lawrence / Minuk, Gerald / Witt-Sullivan, Helga / Yoshida, Eric M

Canadian journal of gastroenterology = Journal canadien de gastroenterologie

2008 Volume 22, Issue 4, Page(s) 388–392

Abstract: Background: Autoimmune hepatitis (AIH) is a chronic inflammatory disease that is successfully treated with prednisone and/or azathioprine immunosuppressive therapy in 70% to 80% of patients. The remaining patients are intolerant or refractory to these ... ...

Abstract	Background: Autoimmune hepatitis (AIH) is a chronic inflammatory disease that is successfully treated with prednisone and/or azathioprine immunosuppressive therapy in 70% to 80% of patients. The remaining patients are intolerant or refractory to these standard medications. Budesonide, a synthetic glucocorticoid, undergoes a high degree of first-pass metabolism, reducing its systemic bioavailability, and has a 15-fold greater affinity for the glucocorticoid receptor than prednisolone. Budesonide may be a potentially useful systemic steroid-sparing immunosuppressive agent in the treatment of AIH. Objective: To review the Canadian experience using budesonide to treat AIH. Methods: Patients with AIH currently or previously treated with budesonide were identified through the Canadian Association for the Study of the Liver membership. Data were collected regarding their clinical and treatment history. Results: A total of nine patients were identified. All patients were female, with an average age of 39 years (range 12 to 66 years). The indications for budesonide were adverse side effects of prednisone in two patients, noncompliance with prednisone and azathioprine in one patient and intolerance to azathioprine resulting in prednisone dependence in the remaining six patients. Patients were treated in doses ranging from 9 mg daily to 3 mg every other day for 24 weeks to eight years. Seven of nine patients had a complete response, defined as sustained normalization of the aminotransferase levels. The remaining two patients were classified as nonresponders (less than a 50% reduction in pretreatment aminotransferase levels). Conclusions: In Canada, budesonide has been successfully used in seven of nine patients with autoimmune hepatitis who were either intolerant to prednisone and azathioprine or prednisone-dependent. No adverse effects were reported with budesonide. Budesonide is potentially a valuable treatment option for AIH patients refractory or intolerant to standard therapy, and is deserving of further study.
MeSH term(s)	Adolescent ; Adult ; Aged ; Alanine Transaminase/blood ; Budesonide/therapeutic use ; Canada ; Child ; Female ; Glucocorticoids/therapeutic use ; Hepatitis, Autoimmune/blood ; Hepatitis, Autoimmune/drug therapy ; Humans ; Middle Aged ; Retrospective Studies ; Treatment Outcome
Chemical Substances	Glucocorticoids ; Budesonide (51333-22-3) ; Alanine Transaminase (EC 2.6.1.2)
Language	English
Publishing date	2008-04-16
Publishing country	Canada
Document type	Journal Article
ZDB-ID	639439-5
ISSN	1916-7237 ; 0835-7900
ISSN (online)	1916-7237
ISSN	0835-7900
DOI	10.1155/2008/509459
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2360: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Does training and experience influence the accuracy of computed tomography colonography interpretation?

Rosenfeld, Greg / Fu, Yi Tzu Nancy / Quiney, Brendan / Qian, Hong / Krygier, Darin / Brown, Jacquie / Vos, Patrick / Tiwari, Pari / Telford, Jennifer / Bressler, Brian / Enns, Robert

World journal of gastroenterology

2012 Volume 20, Issue 6, Page(s) 1574–1581

Abstract: Aim: To evaluate the effect of experience on the accuracy rate of computed tomography colonography (CTC) interpretation and patient preferences/satisfaction for CTC and colonoscopy.: Methods: A prospective, non-randomized, observational study ... ...

Abstract	Aim: To evaluate the effect of experience on the accuracy rate of computed tomography colonography (CTC) interpretation and patient preferences/satisfaction for CTC and colonoscopy. Methods: A prospective, non-randomized, observational study performed in a single, tertiary care center involving 90 adults who underwent CTC followed by colonoscopy on the same day. CTC was interpreted by an abdominal imaging radiologist and then a colonoscopy was performed utilizing segmental un-blinding and re-examination as required. A radiology resident and two gastroenterology (GI) fellows blinded to the results also interpreted the CTC datasets independently. Accuracy rates and trend changes were determined for each reader to assess for a learning curve. Results: Among 90 patients (57% male) aged 55 ± 8.9 years, 39 polyps ≥ 6 mm were detected in 20 patients and 13 polyps > 9 mm in 10 patients. Accuracy rates were 88.9% (≥ 6 mm) and 93.3% (> 9 mm) for the GI Radiologist, 89.8% (≥ 6 mm) and 98.9% (> 9 mm) for the Radiology Resident and 86.7% and 95.6% (≥ 6 mm) and 87.8% and 94.4% (> 9 mm) for each of the GI fellows respectively. The reader's accuracy rate did not change significantly with the percentage change rate ranging between -1.7 to 0.9 (P = 0.12 to 0.56). Patients considered colonoscopy more satisfactory than CTC (30% vs 4%, P < 0.0001), they felt less anxiety during colonoscopy (36% vs 7%, P < 0.0001), they experienced less pain or discomfort during colonoscopy compared to CTC (69% vs 4%, P < 0.0001) and colonoscopy was preferred by 77% of the participants as a repeat screening test for the future. Conclusion: No statistically significant learning curve was identified in CTC interpretation suggesting that further study is required to identify the necessary training to adequately interpret CTC scans.
MeSH term(s)	Adult ; Aged ; Colonography, Computed Tomographic ; Colonoscopy ; Colorectal Neoplasms/diagnosis ; False Positive Reactions ; Female ; Gastroenterology/education ; Humans ; Learning Curve ; Male ; Middle Aged ; Patient Preference ; Prospective Studies ; Regression Analysis ; Reproducibility of Results ; Surveys and Questionnaires
Language	English
Publishing date	2012-08-17
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v20.i6.1574
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6039: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito