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  1. AU="Krykorková, I"
  2. AU=Yan Bing
  3. AU="Nakos, Konstantinos"
  4. AU="Schreiner, Ryan"
  5. AU=Pltz T
  6. AU="Akhmanova, Anna" AU="Akhmanova, Anna"
  7. AU="Goretsky, Anton"
  8. AU="Cordoza, Makayla L"
  9. AU=Midoux Patrick AU=Midoux Patrick
  10. AU="Mundt, H M"
  11. AU=Tsivitse Susan

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  1. Artikel: Nedávno objevené hormony s úcastí v energetické homeostázi.

    Krykorková, I / Nedvídková, J

    Casopis lekaru ceskych

    2003  Band 142, Heft 2, Seite(n) 80–83

    Abstract: Adipocytal hormones resistin and adiponectin and gastric peptide ghrelin are recently discovered hormones, which are considered to take part in energy metabolism regulation. Resistin is expressed in adipose tissue only and its increased levels could ... ...

    Titelübersetzung Recently discovered hormones with a role in energy homeostasis.
    Abstract Adipocytal hormones resistin and adiponectin and gastric peptide ghrelin are recently discovered hormones, which are considered to take part in energy metabolism regulation. Resistin is expressed in adipose tissue only and its increased levels could cause insulin resistance and thus link obesity with type 2 diabetes. Adiponectin, as well as resistin, are products of genes, expressed in adipose tissue. Adiponectin could prevent development of aterosclerosis and it could play a role in anti-inflammatory reactions. Ghrelin is produced mainly in the stomach. Beside its role in long-term regulation of energy metabolism, it is involved in the short-term regulation of feeding. Main roles of resistin, adiponectin and ghrelin are summarised in the presented overview.
    Mesh-Begriff(e) Adiponectin ; Adipose Tissue/metabolism ; Collagen ; Complement C1q ; Energy Metabolism ; Ghrelin ; Hormones, Ectopic/metabolism ; Hormones, Ectopic/physiology ; Humans ; Intercellular Signaling Peptides and Proteins ; Peptide Hormones/metabolism ; Peptide Hormones/physiology ; Proteins/metabolism ; Proteins/physiology ; Resistin ; Stomach/metabolism
    Chemische Substanzen Adiponectin ; Ghrelin ; Hormones, Ectopic ; Intercellular Signaling Peptides and Proteins ; Peptide Hormones ; Proteins ; RETN protein, human ; RETNLB protein, human ; Resistin ; Complement C1q (80295-33-6) ; Collagen (9007-34-5)
    Sprache Tschechisch
    Erscheinungsdatum 2003-04-11
    Erscheinungsland Czech Republic
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 413441-2
    ISSN 1805-4420 ; 0008-7335
    ISSN (online) 1805-4420
    ISSN 0008-7335
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa.

    Nedvídková, Jara / Krykorková, Ivana / Barták, Vladimír / Papezová, Hana / Gold, Philip W / Alesci, Salvatore / Pacak, Karel

    The Journal of clinical endocrinology and metabolism

    2003  Band 88, Heft 4, Seite(n) 1678–1682

    Abstract: Studies have shown that ghrelin plays a major role in energy homeostasis and modulation of feeding behavior. However, little is known about the influence of food consumption on plasma ghrelin levels in humans. Therefore, we investigated responses of ... ...

    Abstract Studies have shown that ghrelin plays a major role in energy homeostasis and modulation of feeding behavior. However, little is known about the influence of food consumption on plasma ghrelin levels in humans. Therefore, we investigated responses of plasma ghrelin to food intake, meal volume and meal nutritional value in healthy volunteers and women with anorexia nervosa (AN). After overnight fasting, all subjects received either a standardized breakfast or fiber. Plasma ghrelin levels were measured before and after the meal. Fasting plasma ghrelin was significantly higher in AN patients than in controls (1,800.6 +/- 47.0 vs. 795.9 +/- 24.3 pg/ml, P < 0.001) (606.8 +/- 15.8 vs. 268.2 +/- 8.2 pmol/l, P < 0.001), and correlated negatively with percentage of body fat in both groups. Ghrelin levels markedly fell after consumption of either a standardized meal or fiber in controls, but not in anorexic women. Thus, we concluded that the acute plasma ghrelin response to food intake, which in healthy individuals is independent of meal caloric value, is impaired in women with AN. This abnormality may be part of a chronic adaptation to prolonged food restriction, which attempts to restore a normal feeding conduct by maintaining the drive to eat.
    Mesh-Begriff(e) Adipose Tissue ; Adult ; Anorexia Nervosa/blood ; Body Composition ; Dietary Fiber/administration & dosage ; Energy Intake ; Fasting ; Female ; Food ; Ghrelin ; Humans ; Nutritive Value ; Peptide Hormones/blood
    Chemische Substanzen Dietary Fiber ; Ghrelin ; Peptide Hormones
    Sprache Englisch
    Erscheinungsdatum 2003-04
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/jc.2002-021669
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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