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  1. Article ; Online: Large impacted foreign body in maxillofacial region: an occupational hazard.

    Nilesh, Kumar / Kshirsagar, Ashok Y

    BMJ case reports

    2021  Volume 14, Issue 1

    MeSH term(s) Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery ; Humans
    Language English
    Publishing date 2021-01-28
    Publishing country England
    Document type Journal Article ; Case Reports
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-239400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Characterization of genetic polymorphisms in oral cancer-related genes pertaining to oxidative stress, carcinogen detoxifying, and DNA repair: A case-control study.

    Tata, Neville Hoshedar / Kshirsagar, Ashok / Nangare, Nitin

    Journal of cancer research and therapeutics

    2022  Volume 18, Issue 4, Page(s) 1023–1029

    Abstract: Background: The genetic polymorphism in the DNA repair and maintenance genes leads to mutations and deregulated growth hormones which have implications in cancer. Apart from identified carcinogens such as tobacco, specific genetic polymorphisms ... ...

    Abstract Background: The genetic polymorphism in the DNA repair and maintenance genes leads to mutations and deregulated growth hormones which have implications in cancer. Apart from identified carcinogens such as tobacco, specific genetic polymorphisms correspond to an individual's risk of oral cancer. The current study aims at identification of differences in genetic polymorphisms in subjects with and without oral cancer in Karad, India.
    Aim/objectives: The aim of the study was to characterize genetic polymorphisms in oral cancer-related genes pertaining to oxidative stress, carcinogen detoxifying, and DNA repair.
    Methodology: A hospital-based case-control was conducted with 150 subjects sorted into cases (n = 75) and controls (n = 75). The polymerase chain reaction-based restriction fragment length polymorphism assay was used to genotype the polymorphisms of selected DNA repair, detoxifying, and oxidative stress-related genes.
    Results: In the cases group, among the DNA repair set, Gene-1 (XRCC1), Gene-3 (XRCC3), Xeroderma Pigmentosum Group-D gene (XPD), and human 8-oxoguanine DNA glycosylase (hOGG1) showed significant genetic polymorphism. Similarly, the genetic polymorphism in the carcinogen detoxifying genes-n-acetyl transferase, GSTP1, and oxidative stress-related gene catalase were noted.
    Statistical analysis: The Cramer's V/odds ratio was applied to estimate the association of genetic risk factors with oral cancer.
    Conclusion: The polymorphisms of XRCC1, XRCC3, XPD, and hOGG1 genes were associated with a higher susceptibility to oral cancer as compared to controls. This information may be a useful novel marker in oral oncology for primary prevention and intervention.
    MeSH term(s) Carcinogens ; Case-Control Studies ; Catalase/genetics ; DNA Glycosylases/genetics ; DNA Repair/genetics ; Genetic Predisposition to Disease ; Genotype ; Hormones ; Humans ; Mouth Neoplasms/genetics ; Oxidative Stress/genetics ; Polymorphism, Genetic ; Transferases/genetics ; X-ray Repair Cross Complementing Protein 1/genetics ; Xeroderma Pigmentosum Group D Protein/genetics
    Chemical Substances Carcinogens ; Hormones ; X-ray Repair Cross Complementing Protein 1 ; XRCC1 protein, human ; Catalase (EC 1.11.1.6) ; Transferases (EC 2.-) ; DNA Glycosylases (EC 3.2.2.-) ; Xeroderma Pigmentosum Group D Protein (EC 3.6.4.12)
    Language English
    Publishing date 2022-09-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.JCRT_1057_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of Nighttime Emergency Surgeries on Patients' Outcome: A Prospective Study.

    Kshirsagar, Ashok / Kannur, Shirish

    Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society

    2020  Volume 26, Issue 2, Page(s) 99–103

    Abstract: Background and aim: The aim of this study was to evaluate the relationship between the time of the day the surgery is conducted and its outcome to provide better protection for patients against fatigue-related errors and reduce the incidence of ... ...

    Abstract Background and aim: The aim of this study was to evaluate the relationship between the time of the day the surgery is conducted and its outcome to provide better protection for patients against fatigue-related errors and reduce the incidence of postoperative morbidity/mortality.
    Methods: All general surgical emergency operations recorded prospectively on the operation theater database of Krishna Hospital and Medical Research Centre, Karad, between April 01, 2018, and March 31, 2019, were included in this study. The operations were categorized according to whether they commenced during the daytime (08:01-20:00 h), or nighttime (20:01-08:00 h). The type of procedure and grade of the participating surgical personnel were also recorded.
    Results: In total, 1128 emergency operations were performed over the study period. The number of emergency procedures performed during the daytime and nighttime was 652 (57.8%) and 476 (42.2%), respectively. Laparotomies and complex vascular procedures collectively accounted for half of all the cases performed after midnight, whereas they represented only 30% of the combined daytime emergency workload. Thirty-two percent (
    Conclusion: When considering a surgical procedure, surgeons must bear in mind that cases that start after the routine hours may face an elevated risk of complications that warrants further evaluation and surgical start times are associated with risk-adjusted patient outcomes.
    Language English
    Publishing date 2020-07-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2641743-1
    ISSN 2278-7100 ; 1117-6806
    ISSN (online) 2278-7100
    ISSN 1117-6806
    DOI 10.4103/njs.NJS_32_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Giant splenic hemangioma in a 10-year-old boy treated with a spleen saving surgery.

    Kolekar, Shreesh / Chincholi, Tejas / Kshirsagar, Ashok / Patankar, Ritvij

    Journal of surgical case reports

    2017  Volume 2017, Issue 11, Page(s) rjx217

    Abstract: Tumors of spleen are rare. The most common benign tumor of spleen is hemangioma. Most splenic hemangiomas (SH) tend to be discovered in mid-30s to mid-50s. SH are discovered incidentally in most of the cases as they are usually asymptomatic. Small ... ...

    Abstract Tumors of spleen are rare. The most common benign tumor of spleen is hemangioma. Most splenic hemangiomas (SH) tend to be discovered in mid-30s to mid-50s. SH are discovered incidentally in most of the cases as they are usually asymptomatic. Small asymptomatic SH can be managed with observation. The treatment options for large hemangiomas are embolization of the splenic arterial branch, splenectomy by laparotomy or laparoscopy. Partial splenectomy can be done if the lesion is small and located at the poles of the spleen. We present a rare case of splenic hemangioma in a 10-year-old boy who presented with a painless palpable mass in the left upper abdomen. On CT scan-A large well-defined cystic lesion with few thin enhancing septa within it is seen involving the spleen. Laparotomy was done followed by Partial splenectomy. The histopathology report was suggestive of Cavernous Hemangioma of spleen.
    Language English
    Publishing date 2017-11-07
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjx217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Acute neonatal parotid abscess: A rare case report.

    Kolekar, Shreesh / Chincholi, Tejas S / Kshirsagar, Ashok / Porwal, Narendra

    African journal of paediatric surgery : AJPS

    2016  Volume 13, Issue 4, Page(s) 199–201

    Abstract: Acute suppurative parotitis is uncommon in children and is very rare in neonates. Most common organism isolated is Staphylococcus aureus. We present a 15-day-old full-term breast-fed female neonate with left-sided acute parotid abscess. The baby ... ...

    Abstract Acute suppurative parotitis is uncommon in children and is very rare in neonates. Most common organism isolated is Staphylococcus aureus. We present a 15-day-old full-term breast-fed female neonate with left-sided acute parotid abscess. The baby presented with a left preauricular swelling, pain and redness. Pus was exuded from left Stensen's duct on compression of the gland externally. Early diagnosis and proper intravenous antibiotics are the keys to the treatment.
    MeSH term(s) Abscess/diagnosis ; Abscess/therapy ; Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Drainage/methods ; Female ; Humans ; Infant, Newborn ; Parotid Gland/diagnostic imaging ; Parotitis/diagnosis ; Parotitis/therapy ; Rare Diseases ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/therapy ; Staphylococcus aureus/isolation & purification ; Ultrasonography
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2016-12-15
    Publishing country India
    Document type Case Reports
    ZDB-ID 2392865-7
    ISSN 0974-5998 ; 0974-5998
    ISSN (online) 0974-5998
    ISSN 0974-5998
    DOI 10.4103/0189-6725.194675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: High-grade myxofibrosarcoma-presented as a large mass of right upper arm.

    Jagtap, Sunil Vitthalrao / Jain, Akash / Jagtap, Swati S / Kshirsagar, Ashok Y

    Indian journal of pathology & microbiology

    2015  Volume 58, Issue 1, Page(s) 105–107

    Abstract: Myxofibrosarcoma is one of the rare soft tissue sarcomas. We present a case of a 65-year-old male having large soft tissue mass over right upper arm associated with surface ulceration. On histopathological study tumor was diagnosed as myxofibrosarcoma - ... ...

    Abstract Myxofibrosarcoma is one of the rare soft tissue sarcomas. We present a case of a 65-year-old male having large soft tissue mass over right upper arm associated with surface ulceration. On histopathological study tumor was diagnosed as myxofibrosarcoma - high grade according to modified FNCLCC grading system. Like many other tumors of connective tissue, soft tissue sarcoma exhibits high recurrence. In our case, tumor showed features of high grade with local recurrence, large size; however, no evidence of metastasis was noted. For this unpredictable clinical behavior, we are presenting this case.
    MeSH term(s) Aged ; Arm/pathology ; Fibrosarcoma/complications ; Fibrosarcoma/diagnosis ; Fibrosarcoma/pathology ; Histocytochemistry ; Humans ; Immunohistochemistry ; Male ; Microscopy ; Myxosarcoma/complications ; Myxosarcoma/diagnosis ; Myxosarcoma/pathology ; Skin Ulcer/etiology ; Skin Ulcer/pathology ; Soft Tissue Neoplasms/complications ; Soft Tissue Neoplasms/diagnosis ; Soft Tissue Neoplasms/pathology ; Vimentin/analysis
    Chemical Substances Vimentin
    Language English
    Publishing date 2015-01
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 197621-7
    ISSN 0974-5130 ; 0377-4929
    ISSN (online) 0974-5130
    ISSN 0377-4929
    DOI 10.4103/0377-4929.151203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 862: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Familial Multiple Basal Cell Carcinoma (Gorlin's Syndrome): A Case Report of a Father and Son.

    Nikam, Balkrishna / Kshirsagar, Ashok / Shivhare, Pratik / Garg, Amitoj

    Indian journal of dermatology

    2013  Volume 58, Issue 6, Page(s) 481–484

    Abstract: Gorlin syndrome is a rare familial disorder characterized by numerous basal cell carcinomas along with facial and skeletal findings. Here, we report a father and son case, presented with features of Gorlin syndrome. ...

    Abstract Gorlin syndrome is a rare familial disorder characterized by numerous basal cell carcinomas along with facial and skeletal findings. Here, we report a father and son case, presented with features of Gorlin syndrome.
    Language English
    Publishing date 2013-11-18
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/0019-5154.119965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 817: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Acute spontaneous gastric perforation in neonates

    Kshirsagar Ashok / Vasisth Gaurav / Ahire Manoj / Kanojiya Rajkamal / Sulhyan Sanjitsingh

    African Journal of Paediatric Surgery, Vol 8, Iss 1, Pp 79-

    A report of three cases

    2011  Volume 81

    Abstract: Gastric perforation in neonates is a rare, serious and life-threatening problem. The precise aetiology is obscure in most cases. By virtue of its high mortality rate, it requires prompt recognition and surgical intervention. We report three cases of ... ...

    Abstract Gastric perforation in neonates is a rare, serious and life-threatening problem. The precise aetiology is obscure in most cases. By virtue of its high mortality rate, it requires prompt recognition and surgical intervention. We report three cases of neonatal gastric perforation managed by early resuscitation and primary repair.
    Keywords Gastric perforation ; neonates ; pneumoperitoneum ; Pediatrics ; RJ1-570 ; Medicine ; R ; DOAJ:Pediatrics ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Surgery ; RD1-811 ; DOAJ:Surgery
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Congenital paraesophageal hiatus hernia with gastric volvulus

    Kshirsagar Ashok / Shinde S / Ahire M / Langade Y

    Journal of Indian Association of Pediatric Surgeons, Vol 13, Iss 1, Pp 36-

    2008  Volume 37

    Abstract: Paraesophageal hiatus hernia is rarely seen in the neonatal period. An intrathoracic gastric volvulus complicating such a hernia is rarer. The upper gastrointestinal tract contrast study is diagnostic. Rapid diagnosis and treatment is essential. It ... ...

    Abstract Paraesophageal hiatus hernia is rarely seen in the neonatal period. An intrathoracic gastric volvulus complicating such a hernia is rarer. The upper gastrointestinal tract contrast study is diagnostic. Rapid diagnosis and treatment is essential. It avoids lethal complications as gastric dilatation, gangrene and perforation, which in turn may lead to cardiopulmonary arrest.
    Keywords Congenital paraesophageal hiatus hernia ; gastric volvulus ; Surgery ; RD1-811 ; Medicine ; R ; DOAJ:Surgery ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2008-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Rhabdomyosarcoma of the breast - a rare malignancy.

    Bhosale, Suresh J / Kshirsagar, Ashok Y / Sulhyan, Soniya R / Sulhyan, Sanjitsingh R

    The American journal of case reports

    2013  Volume 14, Page(s) 250–252

    Abstract: Patient: Female, 60 FINAL DIAGNOSIS: Rhabdomyosarcoma of the breast Symptoms: Lump in axilla Medication: - Clinical Procedure: Mastectomy Specialty: Oncology.: Objective: Rare disease.: Background: Primary nonepithelial malignancies of the breast ... ...

    Abstract Patient: Female, 60 FINAL DIAGNOSIS: Rhabdomyosarcoma of the breast Symptoms: Lump in axilla Medication: - Clinical Procedure: Mastectomy Specialty: Oncology.
    Objective: Rare disease.
    Background: Primary nonepithelial malignancies of the breast include primary breast sarcomas, therapy-related breast sarcomas, the phyllodes tumors, and primary breast lymphomas. They account for less than 5% of all breast neoplasms.
    Case report: We report the case of a 60-year-old postmenopausal female diagnosed with rhabdomyosarcoma with infiltrating duct carcinoma. She was treated with modified radical mastectomy with axillary clearance and postoperative chemotherapy.
    Conclusions: Primary rhabdomyosarcoma of the breast in adults is extremely rare. Rhabdomyosarcomas in adults account for less than 3% of all adult primary soft-tissue sarcomas. Primary breast sarcomas usually present as large painless breast lumps with no associated skin and nipple changes or axillary lymphadenopathy; they are more aggressive and have more rapid growth than epithelial malignancies or benign breast lesions. The tumor can grow to large size, around 5.8 cm. Affected patients are typically women in their 50 s (ranging from 17 to 89 years), but it is also seen in men. The treatment of primary breast sarcomas requires a multidisciplinary approach. Surgery remains the mainstay of therapy. Chemotherapy has no clearly defined role in primary breast or soft-tissue sarcomas. The prognosis of primary breast sarcomas depends on the histologic grade and size of the tumor. They spread locally and hematogenously, but they are not usually associated with axillary lymphadenopathy.
    Language English
    Publishing date 2013-07-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.883976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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