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  1. Article: [Evaluation of the clinical manifestations of COVID-19 in patients with aplastic anemia undergoing immunosuppressive therapy: a prospective cohort study (NICHE)].

    Zhao, J Y / Zhang, L L / Kuang, Z X / Xu, J / Wang, W W / Pan, H / Gao, Z / Li, W W / Fang, L W / Song, Z / Shi, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2024  Volume 44, Issue 11, Page(s) 900–905

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Anemia, Aplastic ; COVID-19 ; Prospective Studies ; Fever ; Immunosuppression Therapy ; Pharyngitis
    Language Chinese
    Publishing date 2024-01-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2023.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [A real-world study of 176 cases with aplastic anemia treated in outpatient].

    Zhang, L L / Yu, X / Fang, L W / Pan, H / Liang, Q / Zhao, J Y / Kuang, Z X / Shi, J

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2021  Volume 42, Issue 1, Page(s) 58–62

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Anemia, Aplastic ; Cyclosporine ; Humans ; Medicine, Chinese Traditional ; Outpatients ; Recurrence
    Chemical Substances Cyclosporine (83HN0GTJ6D)
    Language Chinese
    Publishing date 2021-03-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2021.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Dietary L-arginine supplementation enhances growth performance, intestinal antioxidative capacity, immunity and modulates gut microbiota in yellow-feathered chickens

    Ruan, D / Fouad, A.M / Fan, Q.L / Huo, X.H / Kuang, Z.X / Wang, H / Guo, C.Y / Deng, Y.F / Zhang, C / Zhang, J.H / Jiang, S.Q

    Poultry science. 2020 Dec., v. 99, no. 12

    2020  

    Abstract: This study investigated the effects of dietary Arginine (Arg) on performance, intestinal antioxidative capacity, immunity, and gut microbiota in Chinese yellow-feathered chickens. One thousand two hundred 1-day-old female Qingyuan partridge chickens were ...

    Abstract This study investigated the effects of dietary Arginine (Arg) on performance, intestinal antioxidative capacity, immunity, and gut microbiota in Chinese yellow-feathered chickens. One thousand two hundred 1-day-old female Qingyuan partridge chickens were randomly assigned to 5 groups with 6 replicates of 40 birds each. Chickens were fed diets with 5 levels of total Arg (8.5, 9.7, 10.9, 12.1, and 13.3 g/kg) without antibiotics for 30 d. The ADFI, ADG, and feed conversion ratio were improved with dietary Arg levels (P < 0.05). The proportions of CD3⁺ and CD4⁺/CD8⁺ lymphocytes responded in a linear (P < 0.05) manner and those of CD4⁺ in a linear or quadratic (P < 0.05) manner as dietary Arg levels increased. Dietary Arg level had a linear (P < 0.05) or quadratic (P < 0.05) effect on the gene expression of glutathione peroxidase 1, heme oxygenase 1, nuclear factor erythroid 2–related factor 2, and the activities of glutathione peroxidase and total antioxidative capacity in the jejunum and ileum. The relative expression of IL-1β, myeloid differentiation primary response 88, and Toll-like receptor 4 decreased linearly (P < 0.05) in the ileum with increasing dietary Arg levels; secretory IgA contents were increased. In addition, sequencing data of 16S rRNA indicated that dietary Arg increased the relative abundance of Firmicutes phylum, Romboutsia and Candidatus Arthromitus genera, while decreased that of Clostridium sensu stricto 1. A diet containing 12.1 g Arg/kg promoted growth performance, intestinal antioxidation, and innate immunity and modulated gut microbiota in yellow-feathered chickens.
    Keywords Clostridium ; Toll-like receptor 4 ; antibiotics ; antioxidant activity ; arginine ; chickens ; diet ; enzyme activity ; feed conversion ; females ; gene expression ; glutathione peroxidase ; growth performance ; heme oxygenase (biliverdin-producing) ; ileum ; innate immunity ; interleukin-1beta ; intestinal microorganisms ; jejunum ; ribosomal RNA ; sequence analysis
    Language English
    Dates of publication 2020-12
    Size p. 6935-6945.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2020.09.042
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Dietary L-arginine supplementation enhances growth performance, intestinal antioxidative capacity, immunity and modulates gut microbiota in yellow-feathered chickens.

    Ruan, D / Fouad, A M / Fan, Q L / Huo, X H / Kuang, Z X / Wang, H / Guo, C Y / Deng, Y F / Zhang, C / Zhang, J H / Jiang, S Q

    Poultry science

    2020  Volume 99, Issue 12, Page(s) 6935–6945

    Abstract: This study investigated the effects of dietary Arginine (Arg) on performance, intestinal antioxidative capacity, immunity, and gut microbiota in Chinese yellow-feathered chickens. One thousand two hundred 1-day-old female Qingyuan partridge chickens were ...

    Abstract This study investigated the effects of dietary Arginine (Arg) on performance, intestinal antioxidative capacity, immunity, and gut microbiota in Chinese yellow-feathered chickens. One thousand two hundred 1-day-old female Qingyuan partridge chickens were randomly assigned to 5 groups with 6 replicates of 40 birds each. Chickens were fed diets with 5 levels of total Arg (8.5, 9.7, 10.9, 12.1, and 13.3 g/kg) without antibiotics for 30 d. The ADFI, ADG, and feed conversion ratio were improved with dietary Arg levels (P < 0.05). The proportions of CD3
    MeSH term(s) Animal Feed/analysis ; Animals ; Arginine/pharmacology ; Bacteria/genetics ; Biodiversity ; Chickens/growth & development ; Chickens/immunology ; Chickens/microbiology ; Diet/veterinary ; Dietary Supplements/analysis ; Enzyme Activation/drug effects ; Female ; Gastrointestinal Microbiome/drug effects ; Gastrointestinal Microbiome/genetics ; Immunity/drug effects ; Intestines/drug effects ; Intestines/enzymology ; Oxidoreductases/metabolism ; RNA, Ribosomal, 16S/genetics ; Random Allocation
    Chemical Substances RNA, Ribosomal, 16S ; Arginine (94ZLA3W45F) ; Oxidoreductases (EC 1.-)
    Language English
    Publishing date 2020-09-30
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial, Veterinary
    ZDB-ID 242586-5
    ISSN 1525-3171 ; 0032-5791
    ISSN (online) 1525-3171
    ISSN 0032-5791
    DOI 10.1016/j.psj.2020.09.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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