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Article ; Online: Anti-seizure mechanisms of midazolam and valproate at the β2(L51M) variant of the GABA

Kuanyshbek, Alibek / Wang, Meng / Andersson, Åsa / Tuifua, Marie / Palmer, Elizabeth E / Sachdev, Rani K / Mu, Ting-Wei / Vetter, Irina / Keramidas, Angelo

Neuropharmacology

2022  Volume 221, Page(s) 109295

Abstract: Genetic sequencing is identifying an expanding number of variants of ... ...

Abstract Genetic sequencing is identifying an expanding number of variants of GABA
MeSH term(s) Humans ; Receptors, GABA-A/metabolism ; Valproic Acid/pharmacology ; Valproic Acid/therapeutic use ; Midazolam/pharmacology ; Midazolam/therapeutic use ; Epilepsy/drug therapy ; gamma-Aminobutyric Acid/therapeutic use
Chemical Substances Receptors, GABA-A ; Valproic Acid (614OI1Z5WI) ; Midazolam (R60L0SM5BC) ; gamma-Aminobutyric Acid (56-12-2)
Language English
Publishing date 2022-10-17
Publishing country England
Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID 218272-5
ISSN 1873-7064 ; 0028-3908
ISSN (online) 1873-7064
ISSN 0028-3908
DOI 10.1016/j.neuropharm.2022.109295
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