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Article ; Online: Why are Skipping Breakfast and Skipping Staple Foods Inappropriate Dietary Patterns? The Association with Small Dense Low-Density Lipoprotein Cholesterol Levels.

Kubota, Yoshimi

Journal of atherosclerosis and thrombosis

2023 Volume 30, Issue 10, Page(s) 1313–1314

Language	English
Publishing date	2023-06-21
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2011474-6
ISSN	1880-3873 ; 1340-3478
ISSN (online)	1880-3873
ISSN	1340-3478
DOI	10.5551/jat.ED237
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Article: Understanding the Role of Biogenic Magnetite in Geomagnetic Paleointensity Recording: Insights From Ontong Java Plateau Sediments

Li, Jiaxi / Yamazaki, Toshitsugu / Usui, Yoichi / Sagawa, Takuya / Kubota, Yoshimi / Kuroda, Junichiro

Journal of geophysical research. 2022 June, v. 127, no. 6

2022

Abstract: Marine sediments can preserve continuous paleomagnetic intensity records. Different magnetic minerals may acquire remanent magnetizations differently, so that compositional variations of magnetic mineral assemblages in sediments may hinder extraction of ... ...

Abstract	Marine sediments can preserve continuous paleomagnetic intensity records. Different magnetic minerals may acquire remanent magnetizations differently, so that compositional variations of magnetic mineral assemblages in sediments may hinder extraction of reliable relative paleointensity (RPI) records. To better understand this issue, we conducted a paleo‐ and rock magnetic study of a sediment core from the Ontong Java Plateau, western equatorial Pacific Ocean. RPI estimated by normalizing natural remanent magnetization (NRM) with anhysteretic remanent magnetization (ARM) decreases downcore with an inverse correlation with the ratio of ARM susceptibility to saturation isothermal remanent magnetization. This relationship indicates that the RPI signal weakens as the proportion of biogenic magnetite increases. The NRM–ARM demagnetization diagrams obtained have concave‐down curvature. These observations indicate that the RPI recording efficiency of the biogenic component is lower than that of the terrigenous component if we assume that the magnetizations of the high‐ and low‐coercivity windows are carried dominantly by biogenic and terrigenous components, respectively. This assumption is supported by first‐order reversal curve measurements, transmission electron microscope observations, low‐temperature measurements, and extraction of silicate‐hosted magnetic inclusions from the sediments. Previous studies have suggested that the RPI recording efficiency of biogenic magnetite is higher than that of the terrigenous component, which disagrees with our results. Different concentrations of silicate‐hosted magnetic inclusions in different sedimentary environments might explain this contradiction. We conclude that biogenic magnetite contributes to RPI records with lower efficiency than unprotected terrigenous magnetic minerals in the studied sediments. Changing biogenic magnetite proportions distort ARM‐normalized RPI estimations.
Keywords	geophysics ; magnetism ; magnetite ; research ; transmission electron microscopes ; Pacific Ocean
Language	English
Dates of publication	2022-06
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ISSN	2169-9313
DOI	10.1029/2022JB024387
Database	NAL-Catalogue (AGRICOLA)

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Article: Early Pleistocene (Marine Isotope Stage 40–36) paleoceanography in the northwestern Pacific: Evidence from faunal and oxygen isotope analyses of planktonic foraminifera

Kuwano, Daisuke / Tsuchiya, Yuki / Kameo, Koji / Hayashi, Hiroki / Kubota, Yoshimi / Mantoku, Kanako / Oura, Yuma

Palaeogeography, palaeoclimatology, palaeoecology. 2022 Apr. 15, v. 592

2022

Abstract: The Mid-Pleistocene Transition (MPT) is characterized by a shift from a 41-kyr to a 100-kyr climate cycle of approximately 1.25–0.7 Ma. However, proxy records before the MPT are sparse in the northwestern Pacific region. To investigate the marine ... ...

Abstract	The Mid-Pleistocene Transition (MPT) is characterized by a shift from a 41-kyr to a 100-kyr climate cycle of approximately 1.25–0.7 Ma. However, proxy records before the MPT are sparse in the northwestern Pacific region. To investigate the marine environment around the oceanographic convergence zone of the northwestern Pacific prior to the MPT, we conducted biostratigraphic and oxygen isotope analyses of planktonic foraminifera derived from the upper part of the Kiwada Formation of the Kazusa Group, which is distributed in the Boso Peninsula, central Honshu, Japan. The interval investigated was deposited from Marine Isotope Stages (MIS) 41 to 36 (ca. 1.31–1.20 Ma). The last occurrence of Globigerinoides obliquus is emplaced 30 m above the tephra layer Kd1 during MIS 37. The first occurrence of Neogloboquadrina inglei is placed somewhere below the tephra layer Kd8 and is older than 1.310 Ma. Time-series environmental proxy changes in the planktonic foraminiferal assemblages and oxygen isotopes suggest that the marine environment off the Boso Peninsula was influenced by the Kuroshio Current and the transitional water close to the Kuroshio Front, while the latitudinal shifts of the Kuroshio Front were associated with the glacial-interglacial periods prior to the MPT. Our results suggest that obliquity variability played a significant role in the mid-latitude Pacific Ocean before the MPT, and the hydrographic change in the North Pacific Subtropical Gyre seems to be connected to high-latitude climatic changes. Moreover, the temporary southward migration of the Kuroshio and Subarctic fronts occurred during the late MIS 38, which may be associated with the stronger East Asian winter monsoon. Thus, mid-latitude Pacific oceanographic changes that occurred before the MPT may be linked not only to global remote connections but also to local atmospheric circulation.
Keywords	Japan ; Pleistocene epoch ; Retaria ; atmospheric circulation ; climate ; fauna ; latitude ; marine environment ; monsoon season ; oxygen ; oxygen isotopes ; palaeogeography ; paleoceanography ; paleoclimatology ; paleoecology ; plankton ; tephra ; time series analysis ; Pacific Ocean
Language	English
Dates of publication	2022-0415
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	417718-6
ISSN	0031-0182
ISSN	0031-0182
DOI	10.1016/j.palaeo.2022.110873
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Article ; Online: Millennial-scale paleotemperature change in the Japan Sea during Marine Isotope Stage 3: Impact of meridional oscillation of the subpolar front

Sagawa, Takuya / Hasegawa, Takashi / Narita, Yūsuke / Yokoyama, Masahiro / Kubota, Yoshimi / Okazaki, Yusuke / Goto, Akiko S. / Suzuki, Yoshiaki / Ikehara, Ken / Nakagawa, Takeshi

Palaeogeography, Palaeoclimatology, Palaeoecology. 2023 Sept., v. 626 p.111713-

2023

Abstract: The Japan Sea is a semi-closed marginal sea that has been significantly affected by fluctuations of the East Asian monsoon. Due to its geographic setting, the influence of the monsoon is significant especially during the last glacial period, when the low ...

Abstract	The Japan Sea is a semi-closed marginal sea that has been significantly affected by fluctuations of the East Asian monsoon. Due to its geographic setting, the influence of the monsoon is significant especially during the last glacial period, when the low sea level stand restricted surface water exchange with adjacent seas. Millennial-scale change in the summer monsoon controlled the input of freshwater and nutrients into the Japan Sea during Marine Isotope Stage (MIS) 3, resulting in the deposition of alternating dark- and light-colored sedimentary layers. However, the relationships between the sediment color alternations and winter sea surface conditions, such as temperature and salinity, are not understood. Here, we provide high-resolution Mg/Ca-based winter sea surface temperature (SST) records during MIS3 from two sediment cores from the southern Japan Sea. The SSTs at both sites showed millennial-scale fluctuations with significantly different amplitudes. The southern site had a larger SST amplitude with warmer in dark- and cooler in light-colored intervals. The SST difference between the two cores was greater in dark-colored intervals. The millennial-scale changes in SST difference are probably attributable to meridional migration of the subpolar front, induced by winter monsoons and inflow of the Tsushima Warm Current, which had a northerly (southerly) position during interstadials (stadials). The results suggest that the millennial-scale winter monsoon variability contributed to sediment color alternation via greater cooling during stadials, which enhanced ventilation, in conjunction with the summer monsoon-induced productivity change. Therefore, both the winter and summer monsoons are key drivers of the oceanographic condition in the Japan Sea.
Keywords	Japan ; color ; cooling ; freshwater ; monsoon season ; palaeogeography ; paleoclimatology ; paleoecology ; salinity ; sea level ; sediments ; summer ; surface water ; surface water temperature ; winter ; Japan Sea ; Sea surface temperature ; Winter monsoon ; Dansgaard–Oeschger events ; Subpolar front ; Planktonic foraminifera
Language	English
Dates of publication	2023-09
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	417718-6
ISSN	0031-0182
ISSN	0031-0182
DOI	10.1016/j.palaeo.2023.111713
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Palaeolithic voyage for invisible islands beyond the horizon.

Kaifu, Yousuke / Kuo, Tien-Hsia / Kubota, Yoshimi / Jan, Sen

Scientific reports

2020 Volume 10, Issue 1, Page(s) 19785

Abstract: How Palaeolithic maritime transportation originated and developed is one of the key questions to understand the world-wide dispersal of modern humans that began 70,000-50,000 years ago. However, although the earliest evidence of maritime migration to ... ...

Abstract	How Palaeolithic maritime transportation originated and developed is one of the key questions to understand the world-wide dispersal of modern humans that began 70,000-50,000 years ago. However, although the earliest evidence of maritime migration to Sahul (Australia and New Guinea) has been intensively studied, succeeding development of Paleolithic maritime activity is poorly understood. Here, we show evidence of deliberate crossing of challenging ocean that occurred 35,000-30,000 years ago in another region of the western Pacific, the Ryukyu Islands of southwestern Japan. Our analysis of satellite-tracked buoys drifting in the actual ocean demonstrated that accidental drift does not explain maritime migration to this 1200 km-long chain of islands, where the local ocean flows have kept the same since the late Pleistocene. Migration to the Ryukyus is difficult because it requires navigation across one of the world's strongest current, the Kuroshio, toward an island that lay invisible beyond the horizon. This suggests that the Palaeolithic island colonization occurred in a wide area of the western Pacific was a result of human's active and continued exploration, backed up by technological advancement.
Language	English
Publishing date	2020-12-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-76831-7
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Article: [Determinants of salt taste threshold among urban residents: the KOBE study].

Wakako, Minami / Sata, Mizuki / Kubota, Yoshimi / Nishida, Yoko / Kubo, Sachimi / Higashiyama, Aya / Hirata, Takumi / Kadota, Aya / Hirata, Aya / Miyazaki, Junji / Kawahara, Mizuki / Kuwabara, Kazuyo / Sugiyama, Daisuke / Miyamatsu, Naomi / Miyamoto, Yoshihiro / Okamura, Tomonori

Nihon koshu eisei zasshi] Japanese journal of public health

2023 Volume 70, Issue 5, Page(s) 300–310

Abstract: Objectives　Though having a high salt taste threshold has been associated with hypertension, its exact determinants remains unclear. This study aimed to identify the determinants of salt taste threshold in a community-based population and to determine the ...

Abstract	Objectives　Though having a high salt taste threshold has been associated with hypertension, its exact determinants remains unclear. This study aimed to identify the determinants of salt taste threshold in a community-based population and to determine the relationship between salt taste thresholds and the simultaneous presence of multiple determinants.Methods　Of the 1,117 participants of the baseline survey of the Kobe study, a cohort study of healthy urban residents, aged 40-74 years, with no history of cancer or cardiovascular diseases, nor undergoing treatment for hypertension, diabetes, or dyslipidemia, was conducted. Among them, 1,116 underwent the salt taste threshold test, and urine samples were collected to determine their estimated salt intake. The salt taste threshold test was carried out using SALSAVE
MeSH term(s)	Female ; Humans ; Cohort Studies ; Hypertension/epidemiology ; Sodium Chloride, Dietary/urine ; Taste Threshold ; Urban Population ; Male ; Middle Aged ; Aged
Chemical Substances	Sodium Chloride, Dietary
Language	Japanese
Publishing date	2023-03-10
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	45044-3
ISSN	0546-1766
ISSN	0546-1766
DOI	10.11236/jph.22-062
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Article ; Online: Determinants of double product: a cross-sectional study of urban residents in Japan.

Nakagoshi, Natsuko / Kubo, Sachimi / Nishida, Yoko / Kuwabara, Kazuyo / Hirata, Aya / Sata, Mizuki / Higashiyama, Aya / Kubota, Yoshimi / Hirata, Takumi / Tatsumi, Yukako / Kawamura, Kuniko / Miyazaki, Junji / Miyamatsu, Naomi / Sugiyama, Daisuke / Miyamoto, Yoshihiro / Okamura, Tomonori

Environmental health and preventive medicine

2023 Volume 28, Page(s) 37

Abstract: Background: The current study aimed to investigate the determinants of high double product (DP) by evaluating the association between resting DP, which is calculated as systolic blood pressure (SBP) multiplied by heart rate (HR), and blood test results ... ...

Abstract	Background: The current study aimed to investigate the determinants of high double product (DP) by evaluating the association between resting DP, which is calculated as systolic blood pressure (SBP) multiplied by heart rate (HR), and blood test results and lifestyle factors. Methods: This research included 973 participants in the baseline survey of the KOBE study, which included a cohort of urban residents. The possible DP determinants were identified by examining the association between lifestyle factors and laboratory findings and DP by analyzing covariance adjusted for sex and age. Logistic regression analysis was performed with high DP (SBP × HR ≥ 9145 mmHg beats/min or quintile according to sex) as outcome and DP determinants as independent variables. Results: Age, hematocrit, and gamma-glutamyl transferase (log) level were positively associated with a high DP in both men and women. In addition, a high DP was positively associated with Homeostatic Model Assessment for Insulin Resistance score in women alone. Meanwhile, the amount of exercise was negatively associated with a high DP in men alone. Conclusions: High DP values at rest were associated with insulin resistance, gamma-glutamyl transferase, and the amount of exercise in participants without underlying disease.
MeSH term(s)	Male ; Humans ; Female ; Cross-Sectional Studies ; Insulin Resistance ; Japan ; Urban Population ; Blood Pressure/physiology ; Heart Rate/physiology ; Transferases
Chemical Substances	Transferases (EC 2.-)
Language	English
Publishing date	2023-06-15
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2018758-0
ISSN	1347-4715 ; 1342-078X
ISSN (online)	1347-4715
ISSN	1342-078X
DOI	10.1265/ehpm.23-00002
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Article ; Online: Correction to: Determinants of double product: a cross-sectional study of urban residents in Japan.

Environmental health and preventive medicine

2023 Volume 28, Page(s) 74

Language	English
Publishing date	2023-12-06
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2018758-0
ISSN	1347-4715 ; 1342-078X
ISSN (online)	1347-4715
ISSN	1342-078X
DOI	10.1265/ehpm.23-00220
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Article ; Online: Roles of insolation forcing and CO

Lee, Kyung Eun / Clemens, Steven C / Kubota, Yoshimi / Timmermann, Axel / Holbourn, Ann / Yeh, Sang-Wook / Bae, Si Woong / Ko, Tae Wook

Nature communications

2021 Volume 12, Issue 1, Page(s) 5742

Abstract: Late Pleistocene changes in insolation, greenhouse gas concentrations, and ice sheets have different spatially and seasonally modulated climatic fingerprints. By exploring the seasonality of paleoclimate proxy data, we gain deeper insight into the ... ...

Abstract	Late Pleistocene changes in insolation, greenhouse gas concentrations, and ice sheets have different spatially and seasonally modulated climatic fingerprints. By exploring the seasonality of paleoclimate proxy data, we gain deeper insight into the drivers of climate changes. Here, we investigate changes in alkenone-based annual mean and Globigerinoides ruber Mg/Ca-based summer sea surface temperatures in the East China Sea and their linkages to climate forcing over the past 400,000 years. During interglacial-glacial cycles, there are phase differences between annual mean and seasonal (summer and winter) temperatures, which relate to seasonal insolation changes. These phase differences are most evident during interglacials. During glacial terminations, temperature changes were strongly affected by CO
Language	English
Publishing date	2021-09-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-021-26051-y
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Article ; Online: Relationship of urinary liver-type fatty acid-binding protein with cardiovascular risk factors in the Japanese population without chronic kidney disease: Sasayama study.

Kubota, Yoshimi / Higashiyama, Aya / Marumo, Mikio / Konishi, Masami / Yamashita, Yoshiko / Okamura, Tomonori / Miyamoto, Yoshihiro / Wakabayashi, Ichiro

BMC nephrology

2021 Volume 22, Issue 1, Page(s) 189

Abstract: Background: Urinary liver-type fatty acid-binding protein (L-FABP) is a well-known marker of proximal tubular impairment. We evaluated the relationship between cardiovascular disease (CVD) risk factors and levels of L-FABP in a cross-sectional community- ...

Abstract	Background: Urinary liver-type fatty acid-binding protein (L-FABP) is a well-known marker of proximal tubular impairment. We evaluated the relationship between cardiovascular disease (CVD) risk factors and levels of L-FABP in a cross-sectional community-based study. Participants with normoalbuminuria and normal estimated glomerular filtration rate (eGFR), that is, non-chronic kidney disease (non-CKD), were enrolled in this study. To the best of our knowledge, this is the first study to focus on the association between CVD risk factors and a proximal tubular marker in the Japanese general population with normoalbuminuria and normal eGFR. Methods: The present study is part of the Sasayama study. The participants included 1000 community residents (447 men and 553 women) aged 40-64 years without a history of CVD or renal dysfunction. Out of these participants 375 men and 477 women, defined as non-CKD, were included for further analysis. In each sex, the highest quintile group was considered to have high-normal L-FABP levels. A multiple logistic regression model was used to evaluate the relationship between risk factors for CVD and high-normal L-FABP levels in the non-CKD participants. We performed a similar analysis using the high-normal urinary albumin to creatinine ratio (UACR) as a dependent variable instead of L-FABP. Results: Among the non-CKD participants, in the highest quintile group (Q5, top 20%), L-FABP was ≥2.17 μg/gCre in men and ≥ 2.83 μg/gCre in women. In women, the multivariate odds ratio was 3.62 (1.45-9.00) for high-normal L-FABP in the presence of diabetes mellitus (DM) compared with that in the group without DM. However, the relationship between DM and the UACR level was not significant. In men, DM was significantly associated with high-normal UACR. However, the relationship with L-FABP levels was not significant. Conclusions: The presence of DM was more strongly related to high-normal L-FABP levels than to high-normal UACR in women even at the stage of normoalbuminuria and normal eGFR. Our results were also consistent with the findings of a previous study where women were more prone to nonalbuminuric renal impairment compared to men, although further studies are required to confirm the results.
MeSH term(s)	Adult ; Albuminuria ; Biomarkers/urine ; Cohort Studies ; Cross-Sectional Studies ; Datasets as Topic ; Diabetes Mellitus/urine ; Fatty Acid-Binding Proteins/urine ; Female ; Glomerular Filtration Rate ; Heart Disease Risk Factors ; Humans ; Japan ; Male ; Middle Aged ; Odds Ratio ; Sex Factors
Chemical Substances	Biomarkers ; FABP1 protein, human ; Fatty Acid-Binding Proteins
Language	English
Publishing date	2021-05-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041348-8
ISSN	1471-2369 ; 1471-2369
ISSN (online)	1471-2369
ISSN	1471-2369
DOI	10.1186/s12882-021-02398-8
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