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  1. Article ; Online: Addressing comprehensive complexities a striking familial hypercholesterolemia case study.

    Rasheed, Shazia / Kubra, Ghulam / Baqai, Lubna / Raza, Muhammad Liaquat / Hassan, Fariha / Rizvi, Syed Ghazi Abbas

    The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

    2024  Volume 76, Issue 1, Page(s) 51

    Abstract: Background: Premature aortic involvement and comprehensive management strategies in familial hypercholesterolemia familial hypercholesterolemia (FH), a rare autosomal dominant genetic disorder, poses significant challenges due to its propensity for ... ...

    Abstract Background: Premature aortic involvement and comprehensive management strategies in familial hypercholesterolemia familial hypercholesterolemia (FH), a rare autosomal dominant genetic disorder, poses significant challenges due to its propensity for elevated low-density lipoprotein cholesterol, premature coronary heart disease, and vascular atherosclerosis.
    Case presentation: Unraveling Cardiovascular Complexities: A Striking Familial Hypercholesterolemia. This case study delves into a remarkable instance of FH in a 16-year-old female who presented with chest pain and worsening dyspnea. Diagnostic evaluation revealed distinct electrocardiographic changes, elevated troponin levels, and profound dyslipidemia. Remarkable findings on transthoracic echocardiography, computed tomography angiography, and catheterization prompted multidisciplinary interventions and demonstrated remarkable enhancements in ventricular function, mitral regurgitation, and aortic stenosis.
    Conclusion: The case study underscores the urgency of comprehensive management strategies in confronting the myriad challenges of FH, emphasizing the value of early intervention, innovative therapies, and rigorous imaging modalities for unraveling the intricate cardiovascular manifestations of this condition.
    Language English
    Publishing date 2024-04-20
    Publishing country Germany
    Document type Journal Article
    ISSN 2090-911X
    ISSN (online) 2090-911X
    DOI 10.1186/s43044-024-00483-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: In-Hospital Outcomes of Female Patients With Inferior Wall Myocardial Infarction.

    Kubra, Ghulam / Saghir, Tahir / Rasheed, Shazia / Rehan, Fariha Hasan / Ali, Asad / Abbas, Syed

    Cureus

    2021  Volume 13, Issue 2, Page(s) e13274

    Abstract: Background The aim of this study was to determine the in-hospital outcome of female patients with inferior wall myocardial infarction (MI). Methodology This study was conducted from January to December 2017 at the Department of Cardiology, National ... ...

    Abstract Background The aim of this study was to determine the in-hospital outcome of female patients with inferior wall myocardial infarction (MI). Methodology This study was conducted from January to December 2017 at the Department of Cardiology, National Institute of Cardiovascular Disease, Karachi. A total of 59 women admitted with inferior wall MI were enrolled in the study. In all patients, in-hospital outcomes were observed. Descriptive statistics were applied. Stratification was done using chi-square test, and p-value of ≤0.05 was considered significant. Results The mean age of study participants was 58.80 ± 9.17 years, while 247 (79.7%) participants were above 50 years of age. The mean onset of duration of sign and symptoms of inferior wall MI was 3.48 ± 1.53 hours. There were 36 (61.0%) patients who had diabetes mellitus, 46 (78.0%) had hypertension, 17 (28.8%) were obese, nine (15.3%) had a family history of MI, and three (5.1%) were smokers. There were 43 (72.9%) patients who were illiterate. In our study, eight (13.6%) females were found to have sinus bradycardia, seven (11.9%) had sinus tachycardia, three (5.1%) had atrial fibrillation, and 24 (40.7%) had complete heart block. Mortality was noted in five (8.5%) patients. Conclusions Women with an acute inferior wall MI had a higher rate of complete heart block and adverse in-hospital outcomes. Female gender itself with inferior wall MI may be at risk for in-hospital adverse outcomes.
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.13274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Expression Characterization of Flavonoid Biosynthetic Pathway Genes and Transcription Factors in Peanut Under Water Deficit Conditions.

    Kubra, Ghulam / Khan, Maryam / Munir, Faiza / Gul, Alvina / Shah, Tariq / Hussain, Adil / Caparrós-Ruiz, David / Amir, Rabia

    Frontiers in plant science

    2021  Volume 12, Page(s) 680368

    Abstract: Drought is one of the hostile environmental stresses that limit the yield production of crop plants by modulating their growth and development. Peanut ( ...

    Abstract Drought is one of the hostile environmental stresses that limit the yield production of crop plants by modulating their growth and development. Peanut (
    Language English
    Publishing date 2021-06-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2021.680368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Molecular characterization of

    Kubra, Ghulam / Khan, Maryam / Hussain, Sidra / Iqbal, Tooba / Muhammad, Jan / Ali, Hina / Gul, Alvina / Munir, Faiza / Amir, Rabia

    Saudi journal of biological sciences

    2021  Volume 28, Issue 4, Page(s) 2301–2315

    Abstract: ... Arachis ... ...

    Abstract Arachis hypogaea
    Language English
    Publishing date 2021-01-23
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2021.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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