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  1. Article ; Online: Impact of Precision Medicine in Oncology.

    Kucherlapati, Raju

    Cancer journal (Sudbury, Mass.)

    2023  Volume 29, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Precision Medicine ; Medical Oncology ; Neoplasms/genetics ; Neoplasms/therapy
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Zs.MO 163: Show issues

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  2. Book ; Conference proceedings: Report of the Second International Workshop on Human Chromosome 12 Mapping 1994

    Kucherlapati, Raju

    CW 12 ; held on June 20 - 22, 1994 at New Haven CT (USA)

    1994  

    Event/congress International Workshop on Human Chromosome 12 Mapping (2, 1994, NewHavenConn.)
    Author's details organized by R. Kucherlapati
    Keywords Chromosome Mapping / congresses ; Chromosomes, Human, Pair 12 / congresses
    Language English
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    Note In: Cytogenetics and cell genetics. - ISSN 0301-0171. - 67 (1994), S. 245 - 276
    HBZ-ID HT006401065
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 512 -67- verfügbar in Königswinter Königswinter

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  3. Book: Genetic recombination

    Kucherlapati, Raju

    1988  

    Author's details ed. by Raju Kucherlapati
    Keywords Recombination, Genetic ; Genetik ; Rekombination
    Subject Ladungsrekombination ; Ladungsneutralisation ; Allgemeine Genetik ; Erbbiologie ; Erbforschung ; Erblehre ; Vererbungslehre ; Vererbungswissenschaft ; Erblichkeitslehre
    Language English
    Size XII, 731 S. : Ill., graph. Darst.
    Publisher American Soc. for Microbiology
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT003331255
    ISBN 1-55581-004-7 ; 978-1-55581-004-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1989 A 3102 order for loan Magazin

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  4. Article ; Online: Oliver Smithies (1925-2017).

    Kucherlapati, Raju

    Nature

    2017  Volume 542, Issue 7640, Page(s) 166

    MeSH term(s) Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/therapy ; Animals ; Cystic Fibrosis ; Disease Models, Animal ; Genetic Therapy/history ; Genetic Therapy/methods ; Haptoglobins/chemistry ; History, 20th Century ; History, 21st Century ; Humans ; Mice ; Molecular Biology/history ; Mouse Embryonic Stem Cells/metabolism ; Mutagenesis, Site-Directed/history ; Mutagenesis, Site-Directed/methods ; Nobel Prize ; United Kingdom ; United States
    Chemical Substances Haptoglobins
    Language English
    Publishing date 2017--08
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/542166a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  5. Book: Gene transfer

    Kucherlapati, Raju

    1986  

    Author's details ed. by Raju Kucherlapati
    Keywords Cell Fusion ; Hybrid Cells ; Recombination, Genetic ; Genetic Engineering ; Genexpression ; Genregulation ; Rekombinante DNS ; Gentechnologie ; Gentransfer
    Subject Genübertragung ; Transfer ; Gentechnik ; Genchirurgie ; Genetic engineering ; Genetische Manipulation ; Genetische Technik ; Genmanipulation ; Recombinant DNA ; rDNS ; Rekombinierte DNS ; Rekombinante DNA ; Genetische Regulation ; Transkription ; Genaktivität
    Language English
    Size XIII, 447 S. : Ill., graph. Darst.
    Publisher Plenum Pr
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT002953174
    ISBN 0-306-42325-1 ; 978-0-306-42325-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1987 A 1980 order for loan Magazin

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  6. Article ; Online: Francis H. Ruddle (1929-2013): a pioneer in human gene mapping.

    Kucherlapati, Raju

    Proceedings of the National Academy of Sciences of the United States of America

    2013  Volume 110, Issue 24, Page(s) 9619–9620

    MeSH term(s) Chromosome Mapping/history ; Genomics/history ; History, 20th Century ; History, 21st Century ; Hybrid Cells/metabolism ; United States
    Language English
    Publishing date 2013-05-28
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1308094110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Genetically modified mouse models for biomarker discovery and preclinical drug testing.

    Kucherlapati, Raju

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2012  Volume 18, Issue 3, Page(s) 625–630

    Abstract: The ability to grow pluripotent mouse embryonic stem cells in culture, and to introduce precise genetic modifications into those cells through gene targeting, has greatly facilitated the generation of mouse models of human disease. This technology is ... ...

    Abstract The ability to grow pluripotent mouse embryonic stem cells in culture, and to introduce precise genetic modifications into those cells through gene targeting, has greatly facilitated the generation of mouse models of human disease. This technology is playing a particularly important role in cancer research. In addition to their use in elucidating the role of individual genes or combinations of 2 or more genes, the genetically engineered mouse models are being used to develop biomarkers and for preclinical drug testing. By examining plasma samples from tumor-bearing mice from mice carrying specific mutations in tumor suppressor genes and/or oncogenes, investigators can identify tumor-specific biomarkers that are overexpressed in the tumor cells. These markers are directly relevant to the corresponding human cancer. The ability to generate tumors at the correct anatomical site within the normal cellular environment is augmenting the use of xenografts in drug testing in a preclinical setting.
    MeSH term(s) Animals ; Biomarkers, Tumor/analysis ; Disease Models, Animal ; Drug Screening Assays, Antitumor/methods ; Humans ; Mice ; Mice, Transgenic ; Neoplasms/drug therapy ; Neoplasms/genetics
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2012-02-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-11-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Introduction for: frontiers of personalized cancer medicine.

    Kucherlapati, Raju

    Cancer journal (Sudbury, Mass.)

    2011  Volume 17, Issue 6, Page(s) 403–404

    MeSH term(s) Humans ; Medical Oncology/methods ; Medical Oncology/trends ; Neoplasms/diagnosis ; Neoplasms/therapy ; Personal Health Services/methods ; Personal Health Services/trends
    Language English
    Publishing date 2011-11
    Publishing country United States
    Document type Editorial
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0b013e31823e7006
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    Zs.MO 163: Show issues

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  9. Book: Genomics of cancer

    Kucherlapati, Raju

    (Wednesday afternoon lecture series)

    2014  

    Abstract: CIT): The understanding of the genetics and genomics of cancer is changing very rapidly. The ability to use next-generation sequencing technologies to dissect the genomes of individual cancer patients is helping to drive this increase in knowledge. In ... ...

    Institution National Institutes of Health (U.S.),
    Author's details Raju Kucherlapati
    Series title Wednesday afternoon lecture series
    Abstract (CIT): The understanding of the genetics and genomics of cancer is changing very rapidly. The ability to use next-generation sequencing technologies to dissect the genomes of individual cancer patients is helping to drive this increase in knowledge. In his lecture, Dr. Kucherlapati will describe some of the recent advances and how that knowledge is shedding light on the biology of cancer and helping us develop novel therapeutic approaches.For more information go to http://wals.od.nih.gov.
    MeSH term(s) Neoplasms/genetics ; Genome, Human ; Genomics/methods
    Language English
    Size 1 online resource (1 streaming video file (59 min.)) :, color, sound.
    Document type Book
    Note Closed-captioned. ; Title from title screen.
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Article: Personalized medicine for non-small-cell lung cancer.

    Kucherlapati, Raju

    Oncology (Williston Park, N.Y.)

    2010  Volume 24, Issue 5, Page(s) 399–400

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Genetic Markers ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Precision Medicine ; Protein Kinase Inhibitors/therapeutic use ; Receptor, Epidermal Growth Factor/antagonists & inhibitors ; Receptor, Epidermal Growth Factor/genetics
    Chemical Substances Genetic Markers ; Protein Kinase Inhibitors ; Receptor, Epidermal Growth Factor (EC 2.7.10.1)
    Language English
    Publishing date 2010-04-30
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1067950-9
    ISSN 0890-9091
    ISSN 0890-9091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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