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  1. Article ; Online: Come, Sweet Death: Why Endothelial Cells Die in Fructose.

    Kuebler, Wolfgang M

    American journal of respiratory cell and molecular biology

    2023  Volume 69, Issue 3, Page(s) 247–249

    MeSH term(s) Endothelial Cells/metabolism ; Fructose/metabolism ; Lung/metabolism ; Glycolysis ; Phosphoric Monoester Hydrolases/metabolism
    Chemical Substances Fructose (30237-26-4) ; Phosphoric Monoester Hydrolases (EC 3.1.3.2)
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2023-0195ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2851: Show issues Location:
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  2. Article ; Online: (V)aperçu on the harm of nicotine e-cigarettes.

    Kuebler, Wolfgang M

    The European respiratory journal

    2023  Volume 61, Issue 6

    MeSH term(s) Humans ; Nicotine/adverse effects ; Electronic Nicotine Delivery Systems ; E-Cigarette Vapor ; Tobacco Products ; Pneumonia
    Chemical Substances Nicotine (6M3C89ZY6R) ; E-Cigarette Vapor
    Language English
    Publishing date 2023-06-22
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00886-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  3. Article ; Online: Acute Respiratory Distress Syndrome: Biomarkers, Mechanisms, and Water Channels.

    Kuebler, Wolfgang M

    Anesthesiology

    2019  Volume 130, Issue 3, Page(s) 364–366

    MeSH term(s) Aquaporin 5 ; Biomarkers ; Dyspnea ; Humans ; Pneumonia ; Respiratory Distress Syndrome, Adult
    Chemical Substances Aquaporin 5 ; Biomarkers
    Language English
    Publishing date 2019-01-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000002607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.133: Show issues Location:
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    Zs.MO 199: Show issues

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  4. Article ; Online: Lessons from Cancer: Subcellular Drug Targeting of Mitochondrial HSP90 in Pulmonary Arterial Hypertension.

    Kuebler, Wolfgang M

    American journal of respiratory and critical care medicine

    2018  Volume 198, Issue 1, Page(s) 9–11

    MeSH term(s) Drug Delivery Systems ; HSP90 Heat-Shock Proteins ; Humans ; Hypertension, Pulmonary ; Neoplasms ; Vascular Remodeling
    Chemical Substances HSP90 Heat-Shock Proteins
    Language English
    Publishing date 2018-03-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201801-0200ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Lung-Brain Axis in Ventilator-induced Brain Injury: Enter IL-6.

    Witzenrath, Martin / Kuebler, Wolfgang M

    American journal of respiratory cell and molecular biology

    2021  Volume 65, Issue 4, Page(s) 339–340

    MeSH term(s) Brain/metabolism ; Brain Injuries ; Humans ; Interleukin-6/metabolism ; Lung/metabolism ; Ventilator-Induced Lung Injury ; Ventilators, Mechanical
    Chemical Substances Interleukin-6
    Language English
    Publishing date 2021-06-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2021-0233ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2851: Show issues Location:
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  6. Article ; Online: Connecting the dots: the role of connexins in the pulmonary vascular response to hypoxia.

    Witzenrath, Martin / Kuebler, Wolfgang M

    The European respiratory journal

    2021  Volume 57, Issue 3

    MeSH term(s) Connexins ; Humans ; Hypoxia ; Lung Diseases
    Chemical Substances Connexins
    Language English
    Publishing date 2021-03-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.04573-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 292: Show issues

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  7. Article ; Online: The CypA-netics of Ventilator-induced Lung Injury.

    Witzenrath, Martin / Kuebler, Wolfgang M

    American journal of respiratory and critical care medicine

    2021  Volume 204, Issue 4, Page(s) 385–387

    MeSH term(s) Humans ; Inflammation ; Ventilator-Induced Lung Injury
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202104-0919ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tides of Blood: Cyclic Changes in Lung Blood Volume during a Single Breath.

    Kuebler, Wolfgang M

    American journal of respiratory cell and molecular biology

    2017  Volume 57, Issue 4, Page(s) 386–387

    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2017-0219ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2851: Show issues Location:
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  9. Article ; Online: Implementation of Recommendations for Features and Measurements of Experimental Acute Lung Injury.

    Setiawan, Dwi Cahyo Budi / Simmons, Szandor / Michalick, Laura / Kuebler, Wolfgang M

    American journal of respiratory cell and molecular biology

    2023  Volume 69, Issue 4, Page(s) 484–487

    MeSH term(s) Humans ; Acute Lung Injury ; Respiration, Artificial
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2023-0085LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The oxygen dissociation curve of blood in COVID-19-An update.

    Böning, Dieter / Kuebler, Wolfgang M / Vogel, Dominik / Bloch, Wilhelm

    Frontiers in medicine

    2023  Volume 10, Page(s) 1098547

    Abstract: An impressive effect of the infection with SARS-Co-19 is the impairment of oxygen uptake due to lung injury. The reduced oxygen diffusion may potentially be counteracted by an increase in oxygen affinity of hemoglobin. However, hypoxia and anemia ... ...

    Abstract An impressive effect of the infection with SARS-Co-19 is the impairment of oxygen uptake due to lung injury. The reduced oxygen diffusion may potentially be counteracted by an increase in oxygen affinity of hemoglobin. However, hypoxia and anemia associated with COVID-19 usually decrease oxygen affinity due to a rise in [2,3-bisphosphoglycerate]. As such, COVID-19 related changes in the oxygen dissociation curve may be critical for oxygen uptake and supply, but are hard to predict. A Pubmed search lists 14 publications on oxygen affinity in COVID-19. While some investigations show no changes, three large studies found an increased affinity that was related to a good prognosis. Exact causes remain unknown. The cause of the associated anemia in COVID-19 is under discussion. Erythrocytes with structural alterations of membrane and cytoskeleton have been observed, and virus binding to Band 3 and also to ACE2 receptors in erythroblasts has been proposed. COVID-19 presentation is moderate in many subjects suffering from sickle cell disease. A possible explanation is that COVID-19 counteracts the unfavorable large right shift of the oxygen dissociation curve in these patients. Under discussion for therapy are mainly affinity-increasing drugs.
    Language English
    Publishing date 2023-02-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1098547
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